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*  Rho family of GTPases
Virtually all eukaryotic cells form such processes upon Rho activation. Fibroblasts such as Swiss 3T3 cells are often used to ... Before the cell can bud, Cdc42 is used to locate the region of the cell's membrane that will begin to bulge into the new cell. ... began expressing activated Rho protein in Swiss 3T3 fibroblasts. By the mid-1990s, Rho proteins had been observed to affect the ... Before cells can undergo key processes such as budding, mitosis, or locomotion, it must have some manner of cell polarity. One ...
*  Translationally-controlled tumor protein
"Transcriptional and translational control of cytoplasmic proteins after serum stimulation of quiescent Swiss 3T3 cells". ... Telerman A, Amson R. "TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease". Results and Problems in Cell Differentiation ... Expressing TCTP in U2OS (Human Bone Osteosarcoma Epithelial Cells) protected them from cell death induced by etoposide over ... Reducing TCTP (dTCTP) levels in Drosophila reduces cell size, cell number and organ size, which mimicsDrosophila Rheb (dRheb) ...
*  Start point (yeast)
in 1985 provided evidence for a commitment point in Swiss 3T3 cells, or mouse embryo fibroblasts, when grown in serum-rich or ... "Kinetic Analysis of Regulatory Events in G1 Leading to Proliferation or Quiescence of Swiss 3T3 Cells." PNAS 82 (1985): 5365- ... Thus, larger cells spend less time in the Start checkpoint compared to smaller cells. Morgan, David. The Cell Cycle: Principles ... "Distinct Interactions Select and Maintain a Specific Cell Fate." Molecular Cell 43.4 (2011): 528-39. Mitosis Cell cycle S-phase ...
*  IFRD1
Varnum BC, Lim RW, Herschman HR (1989). "Characterization of TIS7, a gene induced in Swiss 3T3 cells by the tumor promoter ... Cell Res. 288 (1): 35-50. doi:10.1016/S0014-4827(03)00130-7. PMID 12878157. Micheli L, Leonardi L, Conti F, Buanne P, Canu N, ... Cell. Biol. 24 (8): 3514-25. doi:10.1128/mcb.24.8.3514-3525.2004. PMC 381666 . PMID 15060170. Micheli L, Leonardi L, Conti F, ... Cell. Biol. 25 (6): 2242-59. doi:10.1128/MCB.25.6.2242-2259.2005. PMC 1061592 . PMID 15743821. Vietor I, Vadivelu SK, Wick N, ...
*  COX-3
... a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase ... Cao C, Matsumura K, Yamagata K, Watanabe Y (September 1996). "Endothelial cells of the rat brain vasculature express ...
*  COX-2 inhibitor
... a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase ... However, when the ability of all these compounds to kill tumor cells in cell culture was investigated, it turned out that the ... a recent study with various malignant tumor cells showed that celecoxib could inhibit the growth of these cells, even though ... In vitro, the use of COX-2 inhibitors lowers the level of active HDM2 found in neuroblastoma cells. The exact process of how ...
*  3T3 cells
The 3T3 cell line has become the standard fibroblast cell line. Todaro and Green originally obtained their 3T3 cells from Swiss ... 3T3' cells. Specifically, "3T3-L1" is one of the current lines. Swiss 3T3 can be inhibited by temazepam and other ... Cellosaurus entry for 3T3 Nikon MicroscopyU Digital Video Gallery: 3T3 Cell Motility - a set of films of 3T3 cells in culture. ... These cells are also contact inhibited. The cells are sensitive to sarcoma virus and leukemia virus focus formation. 3T3 cells ...
*  MDia1
Further it was shown that p140mDia1 binds to the GTP-bound form of RhoA only by precipitation from Swiss 3T3 cell lysates. ... "The Rho-mDia1 Pathway Regulates Cell Polarity and Focal Adhesion Turnover in Migrating Cells through Mobilizing Apc and c-Src ... Live-cell imaging analysis revealed that mDia1 indeed assembles stress fibers, which are connected at one of their ends to ... Cell Biol. 11: 62-74. doi:10.1038/nrm2816. PMID 19997130. Watanabe N, Madaule P, Reid T, Ishizaki T, Watanabe G, Kakizuka A, ...
*  RPS6KA2
Willard FS, Crouch MF (2001). "MEK, ERK, and p90RSK are present on mitotic tubulin in Swiss 3T3 cells: a role for the MAP ... Cell. 6 (1): 41-51. doi:10.1016/S1097-2765(00)00006-X. PMID 10949026. Gudi T, Casteel DE, Vinson C, et al. (2001). "NO ... Cell. Biol. 15 (8): 4353-63. PMC 230675 . PMID 7623830. Wong EV, Schaefer AW, Landreth G, Lemmon V (1996). "Involvement of ... Cell. Biol. United States. 23 (14): 4796-804. doi:10.1128/MCB.23.14.4796-4804.2003. ISSN 0270-7306. PMC 162206 . PMID 12832467 ...
*  Alan Hall
He first realised that the addition of bovine fetal calf serum (FCS) to Swiss 3T3 cells increased the polymerisation of actin ... DNA from a rhabdomyosarcoma cell line and a fibrosarcoma cell line transformed a NIH/3T3 mouse fibroblast cell line. After ... to localise the mutant V12rac1 protein after being microinjected into the cytoplasm of confluent serum-starved Swiss 3T3 cells ... cells. Downregulation of RhoA in the HBE cell lines using siRNAs showed a lack of apical junction formation in contrast with ...
*  Discovery and development of cyclooxygenase 2 inhibitors
... cDNA species encoding a protein with similar structure to COX-1 while studying phorbol-ester-induced genes in Swiss 3T3 cells. ... COX-2 plays a major role in prostaglandin biosynthesis in inflammatory cells and in the central nervous system. Prostaglandin ... COX-1 is responsible for the synthesis of prostaglandin and thromboxane in many types of cells, including the gastro-intestinal ...
*  PLCB1
... for the termination of insulin-like growth factor I-induced activation of nuclear phospholipase C beta1 in Swiss 3T3 cells". J ... Cell Biol. 4 (5): 329-36. doi:10.1038/ncb781. PMID 11941371. Poduri A, Chopra SS, Neilan EG, Elhosary PC, Kurian MA, Meyer E, ... Cell. Biol. 21 (9): 2981-90. doi:10.1128/MCB.21.9.2981-2990.2001. PMC 86927 . PMID 11287604. Vitale M, Matteucci A, Manzoli L, ... an appraisal of phospholipase C beta 1 behavior in myelodysplastic and leukemia cells". Adv. Enzyme Regul. 47: 2-9. doi:10.1016 ...
*  Pasteurella multocida
... and focal contact assembly in Swiss 3T3 cells. J Biol Chem. 5 Jan 1996; 271(1):439-45. HS agar, by Labconsult, PDF. HS agar, by ... Genetic transformation is the process by which a recipient bacterial cell takes up DNA from a neighboring cell and integrates ... The host cell cycle is also modulated by the toxin, which can act as an intracellular mitogen. P. multocida has been observed ... This bacterium can be effectively treated with β-lactam antibiotics, which inhibit cell wall synthesis. It can also be treated ...
*  List of MeSH codes (A11)
3t3 cells MeSH A11.251.210.700.080 - balb 3t3 cells MeSH A11.251.210.700.550 - nih 3t3 cells MeSH A11.251.210.700.775 - Swiss ... 3t3 cells MeSH A11.329.228.900.080 - balb 3t3 cells MeSH A11.329.228.900.550 - nih 3t3 cells MeSH A11.329.228.900.775 - Swiss ... 3t3-l1 cells MeSH A11.329.228.950 - mesangial cells MeSH A11.329.372.300 - epithelioid cells MeSH A11.329.372.368 - foam cells ... u937 cells MeSH A11.251.210.200 - cho cells MeSH A11.251.210.505 - l cells (cell line) MeSH A11.251.210.520 - llc-pk1 cells ...
*  Madin-Darby Canine Kidney cells
They cultured acini of MDCK cells in collagen gels with or without Swiss 3T3 fibroblasts, in which media could exchange but the ... MDCK cells are used for a wide variety of cell biology studies including cell polarity, cell-cell adhesions (termed adherens ... Epithelial cells in culture grow normally as tight clusters. However, they could be induced to break cell-cell contacts and ... Epithelial cells are typically nonmotile, but can become motile by inhibiting cell-cell junctions or by addition of growth ...
*  Induced stem cells
While initial studies revealed that co-culturing epithelial cells with Swiss 3T3 cells J2 was essential for CRC induction, with ... human iPS cell-derived myeloid cell lines as unlimited cell source for dendritic cell-like antigen-presenting cells". Gene ... "Human Somatic Cell Nuclear Transfer Using Adult Cells". Cell Stem Cell. 14 (6): 777-80. doi:10.1016/j.stem.2014.03.015. PMID ... Fusion of somatic cells with pluripotent stem cells and Transformation of somatic cells into stem cells, using the genetic ...
*  FLII
2001). "The flightless I protein colocalizes with actin- and microtubule-based structures in motile Swiss 3T3 fibroblasts: ... Cell. Biol. 22 (10): 3518-26. doi:10.1128/MCB.22.10.3518-3526.2002. PMC 133791 . PMID 11971982. Bi W, Yan J, Stankiewicz P, et ... Cell. Biol. 24 (5): 2103-17. doi:10.1128/MCB.24.5.2103-2117.2004. PMC 350567 . PMID 14966289. Beausoleil SA, Jedrychowski M, ... 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. ...
*  Protein O-GlcNAc transferase
OGT cleaves Host Cell Factor C1, at one of the 6 repeat sequences. The TPR repeat domain of OGT binds to the carboxyl terminal ... "O15294 (OGT1_HUMAN) Reviewed, UniProtKB/Swiss-Prot". UniProt. Liu F, Shi J, Tanimukai H, Gu J, Gu J, Grundke-Iqbal I, Iqbal K, ... AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes". J. Biol. Chem. 285 (8): 5204- ... OGT glycosylates many proteins including: Histone H2B, AKT1, PFKL, KMT2E/MLL5, MAPT/TAU, Host cell factor C1, and SIN3A. O- ...
*  Jean Lindenmann
... constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virus. Cell 44: ... He served in the Swiss Armed Forces. Lindenmann gained a fellowship from the Swiss Academy of Medical Sciences to do ... those cells became resistant to further infections from live viruses. In 1957, Lindenmann and Isaacs discovered that the cells ... Lindenmann was born on September 18, 1924, in Zagreb, Yugoslavia (present-day Croatia), to a Swiss father and a French mother ...
*  C-Met
Kochhar KS, Johnson ME, Volpert O, Iyer AP (1995). "Evidence for autocrine basis of transformation in NIH-3T3 cells transfected ... Proto-Oncogene Proteins c-met at the US National Library of Medicine Medical Subject Headings (MeSH) UniProtKB/Swiss-Prot entry ... Normally, only stem cells and progenitor cells express MET, which allows these cells to grow invasively in order to generate ... phagocytes and NK cells), thus forming a bridge between an effector and a target cells. This induces the effector cell ...
*  OGT (gene)
OGT cleaves Host Cell Factor C1, at one of the 6 repeat sequences. The TPR repeat domain of OGT binds to the carboxyl terminal ... "O15294 (OGT1_HUMAN) Reviewed, UniProtKB/Swiss-Prot". UniProt. Liu F, Shi J, Tanimukai H, Gu J, Gu J, Grundke-Iqbal I, Iqbal K, ... AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes". The Journal of Biological ... OGT glycosylates many proteins including: Histone H2B, AKT1, PFKL, KMT2E/MLL5, MAPT/TAU, Host cell factor C1, and SIN3A. O- ...