DDT and its breakdown product DDE disturb estrogenic activity and possibly lead to breast cancer. Fetal DDT exposure reduces ... Pesticide resistance describes the decreased susceptibility of a pest population to a pesticide that was previously effective ... Children under the age of six months are more apt to experience exposure from breast milk and inhalation of small particles. ... Recent increases in childhood cancers in throughout North America, such as leukemia, may be a result of somatic cell mutations ...
Wu Q, Wang C, Lu Z, Guo L, Ge Q (July 2012). "Analysis of serum genome-wide microRNAs for breast cancer detection". Clinica ... C polymorphism in microRNA target sites contributes to lung cancer susceptibility". Oncogene. 32 (2): 242-50. doi:10.1038/onc. ... "Serum microRNA profiling and breast cancer risk: the use of miR-484/191 as endogenous controls". Carcinogenesis. 33 (4): 828-34 ... "Microarray analysis of colorectal cancer stromal tissue reveals upregulation of two oncogenic miRNA clusters". Clinical Cancer ...
"Highly homologous hS100A15 and hS100A7 proteins are distinctly expressed in normal breast tissue and breast cancer". Cancer ... "Gene from a psoriasis susceptibility locus primes the skin for inflammation". Science Translational Medicine. 2 (61): 61ra90. ... "CD1a and S100 antigen expression in skin Langerhans cells in patients with breast cancer". The Journal of Pathology. 163 (1): ... They may be present in some breast epithelial cells. S100 proteins have been implicated in a variety of intracellular and ...
Genetic polymorphisms of genes that encode subunits of TFIIH are known to be associated with increased cancer susceptibility in ... many tissues, e.g.; skin tissue, breast tissue and lung tissue. Mutations in the subunits (such as XPD and XPB) can lead to a ... isolated from cancer cell known that time as Basic transcription factor 2, Also, it is isolated from yeast known transcription ... "A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells under Hypoxia". iScience. 23 (9): 101536. Bibcode:2020iSci... ...
... including breast cancer, non-small cell lung cancer, and colorectal cancer. LOX expression was also detected in megakaryocytes ... "The effect of lysyl oxidase polymorphism on susceptibility and prognosis of nonsmall cell lung cancer". Tumour Biology. 33 (6 ... In a rodent model of breast cancer, a small-molecule or antibody inhibitors of LOX abolished metastasis. LOX secreted by ... "Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy". Proceedings of the National Academy ...
Révillion F, Lhotellier V, Hornez L, Bonneterre J, Peyrat JP (January 2008). "ErbB/HER ligands in human breast cancer, and ... variants of the NRG3 gene have been linked to a susceptibility to schizophrenia. An increase in Isoform-specific models of NRG3 ... These groups of proteins also aid cell-cell associations in the breast, heart and skeletal muscles. Four different kinds of ... receptor heterodimerization in development and cancer". The EMBO Journal. 19 (13): 3159-67. doi:10.1093/emboj/19.13.3159. PMC ...
Postmenopausal hormone use and breast cancer associations differ by hormone regimen and histologic subtype. Cancer. 2009 Mar 1; ... and inherited susceptibility genes. She served as a member of the National Cancer Institute's Board of Scientific Counselors, ... "Postmenopausal hormone use and breast cancer associations differ by hormone regimen and histologic subtype". Cancer. 115 (5): ... advancing understanding of the risk factors for breast and ovarian cancers, and research on hormone replacement therapy and ...
In addition to these studies, breast cancer risk studies were performed demonstrating a significant increased breast cancer ... Krzystyniak, Krzystof; Hugo, Patrice; Flipo, Denis; Fournier, Michel (September 1985). "Increased susceptibility to mouse ... "Organochlorine exposure and breast cancer survival". Journal of Clinical Epidemiology. 53 (3): 323-330. doi:10.1016/s0895-4356( ... in which adults showed an increased susceptibility to the compounds compared to children in rats. Like related polychlorinated ...
In human breast cancer samples low expression of the DARC protein is significantly associated with estrogen receptor status, ... A connection has been found between HIV susceptibility and the expression of the Duffy antigen. The absence of the DARC ... "Enhanced expression of Duffy antigen receptor for chemokines by breast cancer cells attenuates growth and metastasis potential ... Men of black African descent are at greater risk of prostate cancer than are men of either European or Asian descendant (60% ...
"Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs". BMC Cancer. 5 ... EMSY has been shown to associate with atopy and susceptibility to poly-sensitisation. EMSY has been shown to interact with ... "EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer". Cell. 115 (5): 523-35. doi:10.1016/S0092-8674(03)00930-9. ... "EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer". Cell. 115 (5): 523-35. doi:10.1016/S0092-8674(03)00930-9. ...
"Oestrogenic activity of parabens in MCF7 human breast cancer cells". J. Steroid Biochem. Mol. Biol. 80 (1): 49-60. doi:10.1016/ ... Löffler H, Effendy I (May 1999). "Skin susceptibility of atopic individuals". Contact Derm. 40 (5): 239-42. doi:10.1111/j.1600- ... ISBN 978-0-470-92680-2. Agner T (1991). "Susceptibility of atopic dermatitis patients to irritant dermatitis caused by sodium ... "Government Says 2 Common Materials Pose Risk of Cancer". The New York Times. Archived from the original on 2019-03-28. ...
The majority of breast diseases either originate from lactiferous ducts or are closely related. The high susceptibility to ... most breast cancers arise from the ductal epithelium (see ductal carcinoma in situ) phyllodes tumor and intraductal papilloma ... Ramsay, D. T.; Kent, J. C.; Hartmann, R. A.; Hartmann, P. E. (2005). "Anatomy of the lactating human breast redefined with ... of the breast mastalgia is frequently caused by an imbalance of breast secretion in the lobules and resorption in the ducts ...
... including leading a study showing an association between Epstein-Barr virus infection and breast cancer in Sudan. Ibrahim won ... human genetic variation contributing to susceptibility to infectious diseases such as malaria and leishmaniasis, and cancer ... He has studied the impact of genetics on susceptibility to diseases including malaria and leishmaniasis. He has also studied ... September 1, 2003). "SLC11A1 (formerly NRAMP1) and susceptibility to visceral leishmaniasis in The Sudan". European Journal of ...
... and breast cancer. Simultaneously, chronic social stressors results in the individual being more susceptible to viral infection ... The enhanced susceptibility to various viral infections maintained the hypothesis that social stress was generally ... social stressors have been linked with altered gene expression in various tissues in addition to immune cells including breast ... gene expression produced by social stress is more likely to result in inflammation-related diseases including various cancers, ...
... breast cancer and Esophageal cancer. Another notable achievement was in establishing a link to the susceptibility of cancer and ... "Comparative morphology of normal mammary glands of four strains of mice varying in their susceptibility to breast cancer". In ... She was a great inspiration to Indian women scientists to work on cancer research, in particular on the subject cancer among ... When Ranadive was working for Tata Memorial Cancer Hospital in Bombay (which later became Cancer Research Centre) in the ...
"In vivo gene expression profile analysis of human breast cancer progression". Cancer Res. 59 (22): 5656-61. PMID 10582678. Ju H ... "TP53BP2 locus is associated with gastric cancer susceptibility". Int J Cancer. 117 (6): 957-60. doi:10.1002/ijc.21281. PMID ... Trigiante G, Lu X (March 2006). "ASPP [corrected] and cancer". Nature Reviews Cancer. 6 (3): 217-26. doi:10.1038/nrc1818. PMID ... J. Cancer. 83 (4): 456-64. doi:10.1002/(SICI)1097-0215(19991112)83:4. 3.0.CO;2-5. PMID 10508479. Mori T, Okamoto H, Takahashi N ...
"VARS2 V552V variant as prognostic marker in patients with early breast cancer". Med. Oncol. 28 (4): 1273-80. doi:10.1007/s12032 ... major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility ... "VARS2 V552V variant as prognostic marker in patients with early breast cancer". Med. Oncol. 28 (4): 1273-80. doi:10.1007/s12032 ...
The American Cancer Society mentioned a 2004 study that found parabens in the breast tissue of mastectomy patients but did not ... However, a recent study has found that prenatal exposure to paraben can increase a child's susceptibility to chronic dermatitis ... "Oestrogenic activity of parabens in MCF7 human breast cancer cells". J Steroid Biochem Mol Biol. 80 (1): 49-60. doi:10.1016/ ... including effects on the male reproductive tract or breast cancer" Animal experiments have shown that parabens have weak ...
... expression also increases with increasing Gleason score (more advanced stages) of prostate cancer. In a study on breast ... QSER1 was also noted as a susceptibility gene for Parkinson's disease. GRCh38: Ensembl release 89: ENSG00000060749 - Ensembl, ... Altered expression of QSER1 is noted in pathological cardiomyopathy, Burkitt's Lymphoma, prostate cancer, and some breast ... cancer response to paclitaxel and fluorouracil‐doxorubicin‐cyclophosphamide chemotherapy, it was noted that breast cancer lines ...
These included the NIEHS Breast Cancer and the Environment Research Centers Program, the NIEHS/EPA Centers for Children's ... Collman became chief of DERT's Susceptibility and Population Health Branch, a post she held until being named acting director ...
The IRF7 pathway was shown to be silenced in some metastatic breast cancer cell lines, which may help the cells avoid the host ... The IRF7 gene and product were shown to be defective in a patient with severe susceptibility to H1N1 influenza, while ... "Entrez Gene: IRF7 interferon regulatory factor 7". Bidwell (2012). "Silencing of Irf7 pathways in breast cancer cells promotes ... susceptibility to other viral diseases such as CMV, RSV, and parainfluenza was unaffected. IRF7 has been shown to interact with ...
"Digital dermatoglyphics and breast cancer". Breast Cancer Research and Treatment. 2 (3): 261-265. doi:10.1007/BF01806940. ISSN ... is any value in the examination of dermal ridge patterns for the diagnosis of disease or for identifying disease susceptibility ... In 1982, Seltzer, et al., conducted a study on patients with breast cancer, and concluded that the presence of six or more ... whorls on a woman's fingertips indicated her being at high risk for breast cancer. Although the study of dermatoglyphics has ...
ZBTB10 in breast cancer". Molecular Cancer Therapeutics. 11 (7): 1421-31. doi:10.1158/1535-7163.MCT-12-0026. PMC 4924623. PMID ... "The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis". The Journal of ... The effects of betulinic acid as an anticancer agent in breast cancer is found to be cannabinoid receptor dependent. Betulinic ... In contrast, epithelial tumors, such as breast, colon, small cell lung and renal cell carcinomas, as well as T-cell leukemia ...
SNP's in NAALADL2 have also been identified in cancer risk GWAS's for breast cancer and Lung cancer. It has been shown that the ... May 2015). "Two susceptibility loci identified for prostate cancer aggressiveness". Nature Communications. 6: 6889. Bibcode: ... In breast cancer, multicellular tumor spheroids (MTS) are 3D cell cultures which acquire differentiated cell-cell junctions and ... September 2007). "A genome-wide association study of breast and prostate cancer in the NHLBI's Framingham Heart Study". BMC ...
... a breast cancer risk assessment test. Beginning from discussions among the alumni of the University of Oklahoma Medical School ... In 2007, Tang uncovered a molecular mechanism that links an Alzheimer's susceptibility gene (known as E4) to the process of ... Thompson led to the creation of a test for assessing breast cancer risk in women. Marketed as OncoVue, the test is produced by ... liver and bladder cancers. In 2006, molecular biologist Gary J. Gorbsky and his lab were the first to reverse the process of ...
"Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: systematic evidence review for ... The five main types of gynecologic cancer include cervical cancer, ovarian cancer, endometrial cancer, vaginal cancer, and ... While ovarian cancer accounts for only 3% of cancers for women in the U.S., it is the fifth leading cause of cancer-related ... "SEER Cancer Statistics Review, 1975-2004." National Cancer Institute (2007). "What Are the Key Statistics About Cervical Cancer ...
June 2019). "Genome-wide enriched pathway analysis of acute post-radiotherapy pain in breast cancer patients: a prospective ... Direk K, Lau W, Small KS, Maniatis N, Andrew T (September 2014). "ABCC5 transporter is a novel type 2 diabetes susceptibility ... Zhao M, Wang T, Liu Q, Cummins S (July 2017). "Copy number alteration of neuropeptides and receptors in multiple cancers". ... Studies have found having high expression of FAM131A is prognostically unfavorable for patients with ovarian cancer or ...
"CYP2C19*17 is associated with decreased breast cancer risk" (PDF). Breast Cancer Research and Treatment. 115 (2): 391-6. doi: ... "Common variants in the CYP2C19 gene are associated with susceptibility to endometriosis". Fertility and Sterility. 102 (2): 496 ... this allele have not been associated with cardiovascular diseases but clearly show a decreased risk of developing breast cancer ... or stroke in a study of 5,740 participants of the cardiovascular cohort of the Malmö Diet and Cancer study; since other studies ...
Breast: mS100a7a15 is weakly expressed in normal mammary gland tissue. Breast cancer: mS100a7a15 is upregulated in DMBA induced ... "Gene from a psoriasis susceptibility locus primes the skin for inflammation". Science Translational Medicine. 2 (61): 61ra90. ... Breast Cancer Research and Treatment (Submitted manuscript). 134 (1): 71-80. doi:10.1007/s10549-011-1920-5. PMID 22189627. ... BMC Cancer. 5: 17. doi:10.1186/1471-2407-5-17. PMC 553966. PMID 15717926. Büchau, AS; Hassan, M; Kukova, G; Lewerenz, V; ...
6-sialyltransferase with altered expression in breast cancer". Mol Med. 8 (1): 42-55. doi:10.1007/BF03402002. PMC 2039932. PMID ... 2007). "Variants of the ST6GALNAC2 promoter influence transcriptional activity and contribute to genetic susceptibility to IgA ...