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*  Neutrophil cytosolic factor 4
The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a ...
*  Antimicrobial properties of copper
Samuni, A.; Chevion, M.; Czapski, G. (1984). "Roles of Copper and Superoxide Anion Radicals in the Radiation-Induced ... Copper facilitates deleterious activity in superoxide radicals. Repeated redox reactions on site-specific macromolecules ...
*  Copper toxicity
... such as with the superoxide radical through Cu-Zn dependent superoxide dismutase.[not in citation given] Excessive free copper ...
*  SOD3
... superoxide dismutase 3, extracellular". Zelko IN, Mariani TJ, Folz RJ (August 2002). "Superoxide dismutase multigene ... Extracellular superoxide dismutase [Cu-Zn] is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member ... Adachi T, Ohta H, Yamada H, Futenma A, Kato K, Hirano K (November 1992). "Quantitative analysis of extracellular-superoxide ... Oury TD, Crapo JD, Valnickova Z, Enghild JJ (July 1996). "Human extracellular superoxide dismutase is a tetramer composed of ...
*  Neutrophil cytosolic factor 2
This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene ...
*  Copper peptide GHK-Cu
... superoxide dismutase (SOD), detoxification (metallothioneins), blood clotting (blood clotting factors V and VIII), melanin ...
*  Free-radical theory of aging
Afanas'ev suggests the superoxide dismutation activity of CuZnSOD demonstrates an important link between life span and free ... Miyazawa found mitochondrial superoxide anion production can lead to organ atrophy and dysfunction via mitochondrial- mediated ... Strictly speaking, the free radical theory is only concerned with free radicals such as superoxide ( O2− ), but it has since ... Free radicals that are thought to be involved in the process of aging include superoxide and nitric oxide. Specifically, an ...
*  Superoxide dismutase
... the reaction of superoxide with SOD is first order with respect to superoxide concentration. Moreover, superoxide dismutase has ... SOD out-competes damaging reactions of superoxide, thus protecting the cell from superoxide toxicity. The reaction of ... Because the uncatalysed dismutation reaction for superoxide requires two superoxide molecules to react with each other, the ... oxidation of superoxide) Cu+-SOD + O2− + 2H+ → Cu2+-SOD + H2O2 (oxidation of copper; reduction of superoxide) The general form ...
*  Superoxide
A superoxide, also known as hyperoxide, is a compound that contains the superoxide anion with the chemical formula O− 2. The ... Superoxides are found in alkali metals and alkali earth metals. Superoxides are compounds in which the oxidation number of ... Because superoxide is toxic, nearly all organisms living in the presence of oxygen contain isoforms of the superoxide- ... As a free radical, superoxide has a strong EPR signal, and it is possible to detect superoxide directly using this method when ...
*  Potassium superoxide
It is a rare example of a stable salt of the superoxide ion. Potassium superoxide is used as a CO 2 scrubber, H 2O dehumidifier ... Potassium superoxide is produced by burning molten potassium in an atmosphere of oxygen. K + O 2 → KO 2 The salt consists of K+ ... Potassium superoxide is the inorganic compound with the formula KO 2. It is a yellow paramagnetic solid that decomposes in ... Even dry superoxide can produce an impact-sensitive explosive compound when combined with organic oils such as kerosene. In ...
*  Superoxide reductase
... is an enzyme that catalyzes the conversion of highly reactive and toxic superoxide (O2−) into less toxic ... "Reaction of the desulfoferrodoxin from Desulfoarculus baarsii with superoxide anion. Evidence for a superoxide reductase ... Yeh AP, Hu Y, Jenney FE, Adams MW, Rees DC (2000). "Structures of the superoxide reductase from Pyrococcus furiosus in the ... The 3 substrates of this enzyme are reduced rubredoxin, superoxide, and H+, whereas its two products are rubredoxin and H2O2. ...
*  Lithium superoxide
... (LiO2) is an inorganic compound which has only been isolated in matrix isolation experiments at 15-40 K. It ... Lithium superoxide is extremely reactive because of the odd electron present in the π* molecular orbital. There have been quite ... Rarely are superoxides stable for any significant amount of time as they exist merely as transition states. In January 2016, ... Das, U.; Lau, K.C.; Redfern, P.C.; Curtiss, L.A. Structure and Stability of Lithium Superoxide Clusters and Relevance to Li-O2 ...
*  Sodium superoxide
... is the inorganic compound with the formula NaO2. This yellow-orange solid is a salt of the superoxide anion. ... It crystallizes in the NaCl motif.[citation needed] Hayyan M., Hashim M.A., AlNashef I.M., Superoxide Ion: Generation and ... DOI: 10.1021/acs.chemrev.5b00407 Stephen E. Stephanou, Edgar J. Seyb Jr., Jacob Kleinberg "Sodium Superoxide" Inorganic ...
*  Superoxide dismutase mimetics
Superoxide dismutase (SOD) mimetics are synthetic compounds that mimic the native superoxide dismutase enzyme. SOD mimetics ... Mn) is reduced by superoxide, yielding molecular oxygen and a reduced form of manganese (Mn-1). The metal (Mn-1) is then ... Mn (II) complexes are found to be more stable in vivo and have high specificity for the superoxide anion, preventing unwanted ... Mn (III) Salen complexes are found to be more stable than other iron or manganese mimics of superoxide dismutase. In certain ...
*  Nickel superoxide dismutase
... (Ni-SOD) is a metalloenzyme that, like the other superoxide dismutases, protects cells from ... Sheng, Yuewei (2014). "Superoxide Dismutases and Superoxide Reductases". Chemical Reviews. 114: 3854-3918. doi:10.1021/ ... The equation for the disproportionation of superoxide is shown below: 2 O 2 − + 2 H + → N i c k e l S u p e r o x i d e D i s m ... Nickel superoxide dismutase is primarily found in bacteria. The only know example of a eukaryote expressing a nickel containing ...
*  Cytochrome c
However, superoxide is often produced with nitric oxide. In the presence of nitric oxide, the reduction of cytochrome c3+ is ... As superoxide is produced, the number of oxidized cytochrome c3+ increases, and reduced cytochrome c2+ decreases. ... McCord JM, Fridovich I (Nov 1969). "Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)". The Journal of ... and it does so by removing superoxide (O2-) and hydrogen peroxide (H2O2) from mitochondria. Therefore, not only is cytochrome c ...
*  Streptomyces seoulensis
ISBN 0-387-68233-3. CS1 maint: Extra text: authors list (link) Packer, edited by Lester (2002). Superoxide dismutase. San Diego ... from is involved in expression of nickel-containing superoxide dismutase". FEMS Microbiology Letters. 228 (1): 21-26. doi: ... "Examination of the Nickel Site Structure and Reaction Mechanism in Superoxide Dismutase". Biochemistry. 38 (12): 3744-3752. doi ...
*  Aconitase
Gardner, Paul R. (2002). "Aconitase: Sensitive target and measure of superoxide". Superoxide Dismutase. Methods in Enzymology. ... The iron sulfur cluster is highly sensitive to oxidation by superoxide. Aconitase employs a dehydration-hydration mechanism. ...
*  Joe M. McCord
Keele BB, McCord JM, Fridovich I (November 1970). "Superoxide dismutase from escherichia coli B. A new manganese-containing ... McCord JM, Fridovich I (November 1969). "Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)". J. Biol. ... he and his supervisor Irwin Fridovich were the first to describe the enzymatic activity of superoxide dismutase. McCord joined ... "The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy". Free ...
*  Oxidative stress
... in some cases catalyzing the production of superoxide from dioxygen or hydrogen peroxide from superoxide. The immune system ... These include superoxide (•O− 2), nitric oxide (•NO) and their particularly reactive product, peroxynitrite (ONOO-). Although ... Base damage is mostly indirect and caused by reactive oxygen species (ROS) generated, e.g. O2− (superoxide radical), OH ( ... Some of the less reactive of these species (such as superoxide) can be converted by oxidoreduction reactions with transition ...
*  Irwin Fridovich
Fridovich I (1995). "Superoxide radical and superoxide dismutases". Annual Review of Biochemistry. 64: 97-112. doi:10.1146/ ... zinc superoxide dismutase (SOD),-to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct ... Kresge N, Simoni RD, Hill RL (2006). "Forty Years of Superoxide Dismutase Research: the Work of Irwin Fridovich (JBC Classics: ... He spent the rest of his career studying the biochemical mechanisms of SOD and of biological superoxide toxicity, using ...
*  Reactive nitrogen species
... superoxide) → ONOO− (peroxynitrite) Superoxide anion (O2−) is a reactive oxygen species that reacts quickly with nitric oxide ( ... RNS are produced in animals starting with the reaction of nitric oxide (•NO) with superoxide (O2•−) to form peroxynitrite (ONOO ... Guzik TJ, West NE, Pillai R, Taggart DP, Channon KM (June 2002). "Nitric oxide modulates superoxide release and peroxynitrite ... Reactive nitrogen species (RNS) are a family of antimicrobial molecules derived from nitric oxide (•NO) and superoxide (O2•−) ...
*  Peroxynitrous acid
It is formed in vivo from the diffusion-controlled reaction of nitrogen monoxide (•NO) and superoxide (O•− 2). It isomerises ...
*  Molecular graphics
Three-dimensional structure of Cu, Zn superoxide dismutase. Superoxide and superoxide disumases. Ed. By A.M. Michelson, J.M. ... The Richardson group published partial atomic structure results of the protein superoxide dismutase the same year, in 1977. All ...
*  Dual oxidase 1
This unstable superoxide, generated at the extracellular surface, may rapidly convert to hydrogen peroxide and be utilized by ... The current model for ROS generation by C. elegans DUOX1 (CeDUOX1) proposes that superoxide is generated through reduction of ... Cross AR, Jones OT (May 1991). "Enzymic mechanisms of superoxide production". Biochim. Biophys. Acta. 1057 (3): 281-98. doi: ... superoxide dismutase activity, instead of peroxidase activity; a novel peroxidase mechanism; a protein-protein or Ca2+ induced ...