One example of an imidazolate complex from biochemistry is found at the active site of copper-containing superoxide dismutase. ...
"A retrospective study of the prevalence of the canine degenerative myelopathy associated superoxide dismutase 1 mutation (SOD1: ...
... and characterization of a novel cold-active superoxide dismutase from the Antarctic strain Aspergillus glaucus 363" (PDF). ...
Mutations in the superoxide dismutase 1 (SOD-1) gene was discovered to be linked to the development of ALS. Cudkowicz partnered ...
SOD1, which codes for superoxide dismutase 1, is the second most common gene associated with ALS and causes about 12% of ... In 1993, scientists discovered that mutations in the gene (SOD1) that produces the Cu-Zn superoxide dismutase (SOD1) enzyme ... "Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury ... This enzyme is a powerful antioxidant that protects the body from damage caused by superoxide, a toxic free radical generated ...
Gaudet, Mia M. (2005). Interactions of lifestyle factors, manganese superoxide dismutase, catechol-O-methyltransferase, and the ... Her 2005 dissertation was titled Interactions of lifestyle factors, manganese superoxide dismutase, catechol-O- ...
Oxidative Stress Response: Proteins such as catalase, superoxide dismutase, & alkyl hydroperoxide reductase protect the ...
One other successful approach is sequence analysis of the manganese-dependent superoxide dismutase gene, described by Poyart et ...
"A retrospective study of the prevalence of the canine degenerative myelopathy associated superoxide dismutase 1 mutation (SOD1: ...
Coenzyme Q10 Manganese, particularly when in its +2 valence state as part of the enzyme called superoxide dismutase (SOD). ...
Thiffault C, Quirion R, Poirier J (March 1998). "Effect of the MAO-B inhibitor, MDL72974, on superoxide dismutase activity and ...
As a mitigative, supplementation of 2 mg/day copper as glycinate chelate safely increases Cu-Zn superoxide dismutase activity. ...
Superoxide dismutase, malate dehydrogenase (decarboxylating), ferredoxin, adenylate kinase and NADH:ferredoxin oxido-reductase ...
Copper is also found in many superoxide dismutases, proteins that catalyze the decomposition of superoxides by converting it ( ... Copper is an integral part of the antioxidant enzyme copper-zinc superoxide dismutase, and has a role in iron homeostasis as a ... Levels of copper-containing enzymes, such as cytochrome c oxidase, superoxide dismutase, and diaminase oxidase, vary not only ... zinc superoxide dismutase). It is called "copper chaperone for SOD1" (CCS), and excellent animal data supports its use as a ...
... and superoxide dismutase. In 2011, several compounds (antifungals, fungicides, and biocides) where shown to effectively inhibit ...
Superoxide dismutases protect against oxidative stress but have little or no effect on lifespan in C. elegans"". Genes and ... "No increase in life span in Caenorhabditis elegans upon treatment with the superoxide dismutase mimetic EUK-8"". Free Radical ... "Increased lifespan from over-expression of superoxide dismutase in C. elegans is not caused by decreased oxidative damage"". ...
... and superoxide dismutase) to "neutralise" reactive oxygen species. It also forms the dark-brown, water-soluble pigment melanin ...
Another mouse model was generated in which a mutation of superoxide dismutase I (SOD1) is expressed in an Aptx−/− mouse. The ...
January 1994). "The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in ... Administration of recombinant human superoxide dismutase (rh-SOD) in recipients of cadaveric renal allografts demonstrated ...
Huret JL (March 1987). "Down syndrome with duplication of a region of chromosome 21 containing the CuZn superoxide dismutase ...
... and superoxide dismutase (encoded by sodC). It has also been found, using comparative proteomic analysis with B. pseudomallei, ...
Zn Superoxide Dismutase". Journal of Molecular Biology. 324 (2): 247-256. doi:10.1016/S0022-2836(02)01090-2. PMID 12441104. ...
Superoxide is a free radical and causes biochemical damage, but is neutralised by the action of the enzyme superoxide dismutase ... also formed in small quantities when the dissociation of oxyhemoglobin results in the formation of methemoglobin and superoxide ...
Diethyldithiocarbamate inhibits superoxide dismutase, which can both have antioxidant and oxidant effects on cells, depending ...
Some (but not all) studies have shown that the activity of the superoxide dismutase enzyme is elevated in Down syndrome. SOD ...
Superoxide Dismutase (SOD)". Angew. Chem. 46 (7): 1079-1082. doi:10.1002/anie.200603093. PMID 17191298. Marchetti, Alessandro; ...
Kumar S, Kalyanasundaram GT, Gummadi SN (Feb 2011). "Differential response of the catalase, superoxide dismutase and glycerol-3 ...
Genes that encode the enzyme superoxide dismutase are also common, and this gene also has an established role in chromate ... and superoxide". J. Bacteriol. 190 (21): 6996-7003. doi:10.1128/JB.00289-08. PMC 2580707. PMID 18776016. (Orphaned articles ...
Additionally, M. stellatus makes use of scavenging enzymes including: catalase, superoxide dismutase, glutathione reductase, ...
... superoxide dismutases, thioredoxin reductase and thioredoxins. Deficiencies in the availability of these antioxidant proteins ...