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*  Copper toxicity
... such as with the superoxide radical through Cu-Zn dependent superoxide dismutase.[not in citation given] Excessive free copper ...
*  SOD3
... superoxide dismutase 3, extracellular". Zelko IN, Mariani TJ, Folz RJ (August 2002). "Superoxide dismutase multigene ... Extracellular superoxide dismutase [Cu-Zn] is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member ... Oury TD, Crapo JD, Valnickova Z, Enghild JJ (July 1996). "Human extracellular superoxide dismutase is a tetramer composed of ... Serra V, von Zglinicki T, Lorenz M, Saretzki G (February 2003). "Extracellular superoxide dismutase is a major antioxidant in ...
*  Copper peptide GHK-Cu
... superoxide dismutase (SOD), detoxification (metallothioneins), blood clotting (blood clotting factors V and VIII), melanin ...
*  Free-radical theory of aging
Lund DD, Chu Y, Miller JD, Heistad DD (2009). "Protective effect of extracellular superoxide dismutase on endothelial function ... "Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans". PLoS Genetics. 5 (2): ... demonstrated the role of endogenous extracellular superoxide dismutase in protecting against endothelial dysfunction during the ... beta-carotene and Superoxide dismutase will slow the process of aging by preventing free radicals from oxidizing sensitive ...
*  Superoxide dismutase
... the reaction of superoxide with SOD is first order with respect to superoxide concentration. Moreover, superoxide dismutase has ... "Phenotypes of mice lacking extracellular superoxide dismutase and copper- and zinc-containing superoxide dismutase". The ... Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the ... Superoxide dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the ...
*  Superoxide dismutase mimetics
Superoxide dismutase (SOD) mimetics are synthetic compounds that mimic the native superoxide dismutase enzyme. SOD mimetics ... Mn (III) Salen complexes are found to be more stable than other iron or manganese mimics of superoxide dismutase. In certain ... Thompson, JS; Chu, Y; Glass, J; Tapp, A; Brown, SA (May 2010). "The manganese superoxide dismutase mimetic, M40403, protects ... Miller, Anne-Francis (April 2004). "Superoxide dismutases: active sites that save, but a protein that kills". Current Opinion ...
*  Nickel superoxide dismutase
... (Ni-SOD) is a metalloenzyme that, like the other superoxide dismutases, protects cells from ... repressing the transcription of other superoxide dismutases. In particular, expression of iron superoxide dismutase (Fe-SOD) is ... Sheng, Yuewei (2014). "Superoxide Dismutases and Superoxide Reductases". Chemical Reviews. 114: 3854-3918. doi:10.1021/ ... Nickel superoxide dismutase is primarily found in bacteria. The only know example of a eukaryote expressing a nickel containing ...
*  Cytochrome c
McCord JM, Fridovich I (Nov 1969). "Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)". The Journal of ... However, superoxide is often produced with nitric oxide. In the presence of nitric oxide, the reduction of cytochrome c3+ is ... As superoxide is produced, the number of oxidized cytochrome c3+ increases, and reduced cytochrome c2+ decreases. ... and it does so by removing superoxide (O2-) and hydrogen peroxide (H2O2) from mitochondria. Therefore, not only is cytochrome c ...
*  Streptomyces seoulensis
ISBN 0-387-68233-3. CS1 maint: Extra text: authors list (link) Packer, edited by Lester (2002). Superoxide dismutase. San Diego ... from is involved in expression of nickel-containing superoxide dismutase". FEMS Microbiology Letters. 228 (1): 21-26. doi: ... "Examination of the Nickel Site Structure and Reaction Mechanism in Superoxide Dismutase". Biochemistry. 38 (12): 3744-3752. doi ...
*  Aconitase
Gardner, Paul R. (2002). "Aconitase: Sensitive target and measure of superoxide". Superoxide Dismutase. Methods in Enzymology. ... The iron sulfur cluster is highly sensitive to oxidation by superoxide. Aconitase employs a dehydration-hydration mechanism. ...
*  Joe M. McCord
Keele BB, McCord JM, Fridovich I (November 1970). "Superoxide dismutase from escherichia coli B. A new manganese-containing ... McCord JM, Fridovich I (November 1969). "Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)". J. Biol. ... he and his supervisor Irwin Fridovich were the first to describe the enzymatic activity of superoxide dismutase. McCord joined ... "The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy". Free ...
*  Irwin Fridovich
Fridovich I (1995). "Superoxide radical and superoxide dismutases". Annual Review of Biochemistry. 64: 97-112. doi:10.1146/ ... zinc superoxide dismutase (SOD),-to protect organisms from the toxic effects of superoxide free radicals formed as a byproduct ... Kresge N, Simoni RD, Hill RL (2006). "Forty Years of Superoxide Dismutase Research: the Work of Irwin Fridovich (JBC Classics: ... His discovery of the superoxide dismutase reaction essentially started the field of oxygen free radicals in biology and ...
*  Petkau effect
Petkau also discovered that superoxide dismutase was elevated in the leukocytes (white blood cells) in a sub-population of ... Petkau conducted further experiments with simulated cells in 1976 and found that the enzyme superoxide dismutase protected the ... Petkau, A. (June 1987). "Role of superoxide dismutase in modification of radiation injury". The British Journal of Cancer. ... 10 mSv in 6 months), further supporting the hypothesis that superoxide dismutase is a radioprotective agent. Thus, Petkau's ...
*  Metalloprotein
Otherwise, the superoxide ion must be destroyed before it does unwanted damage in a cell. The superoxide dismutase enzymes ... It involves both oxidation and reduction of superoxide ions. The superoxide dismutase (SOD) group of enzymes increase the rate ... This enzyme also contains zinc ions for stabilization and is activated by copper chaperone for superoxide dismutase (CCS). ... Packer, L. (editor) (2002). Superoxide Dismutase: 349 (Methods in Enzymology). Academic Press. ISBN 0-12-182252-4. CS1 maint: ...
*  CCS (gene)
Copper chaperone for superoxide dismutase is a metalloprotein that is responsible for the delivery of Cu to superoxide ... Culotta VC, Klomp LW, Strain J, Casareno RL, Krems B, Gitlin JD (Sep 1997). "The copper chaperone for superoxide dismutase". ... Moore SD, Chen MM, Cox DW (2000). "Cloning and mapping of murine superoxide dismutase copper chaperone (Ccsd) and mapping of ... Rae TD, Torres AS, Pufahl RA, O'Halloran TV (Feb 2001). "Mechanism of Cu,Zn-superoxide dismutase activation by the human ...
*  Resveratrol
... manganese superoxide dismutase in disease". Free Radic. Res. 34 (4): 325-36. doi:10.1080/10715760100300281. PMID 11328670. ...
*  Superoxide reductase
Jenney FE, Verhagen MF, Cui X, Adams MW (1999). "Anaerobic microbes: oxygen detoxification without superoxide dismutase". ... Superoxide reductase is an enzyme that catalyzes the conversion of highly reactive and toxic superoxide (O2−) into less toxic ... "Reaction of the desulfoferrodoxin from Desulfoarculus baarsii with superoxide anion. Evidence for a superoxide reductase ... Yeh AP, Hu Y, Jenney FE, Adams MW, Rees DC (2000). "Structures of the superoxide reductase from Pyrococcus furiosus in the ...
*  SOD2
Superoxide dismutase 2, mitochondrial (SOD2), also known as manganese-dependent superoxide dismutase (MnSOD), is an enzyme ... As a member of the iron/manganese superoxide dismutase family, this protein transforms toxic superoxide, a byproduct of the ... Zelko IN, Mariani TJ, Folz RJ (Aug 2002). "Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD ( ... This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a ...
*  Glisodin
Superoxide dismutase Oxidative stress Antioxidants C. Muth; Y. Glenz; M. Klaus; P. Radermacher; Guenter Speit; X. Leverve (2004 ... Superoxide dismutase (SOD) helps to slow the creation of ROS, ultimately playing a key role in the defense against cell damage ... which typically contains high quantities of the enzyme superoxide dismutase (SOD) Gliadin, a wheat protein designed to protect ...
*  SOD1
Superoxide dismutase [Cu-Zn] also known as superoxide dismutase 1 or SOD1 is an enzyme that in humans is encoded by the SOD1 ... SOD1 binds copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals ... "Entrez Gene: SOD1 superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))". Danial NN, Korsmeyer SJ (January ... Pan L, Yoshii Y, Otomo A, Ogawa H, Iwasaki Y, Shang HF, Hadano S (2012). "Different human copper-zinc superoxide dismutase ...
*  Oxygen toxicity
Oury, TD; Ho, YS; Piantadosi, Claude A; Crapo, JD (1992). "Extracellular superoxide dismutase, nitric oxide, and central ... Freiberger, John J; Coulombe, Kathy; Suliman, Hagir; Carraway, Martha-sue; Piantadosi, Claude A (2004). "Superoxide dismutase ... One species produced by the body, the superoxide anion (O 2−), is possibly involved in iron acquisition. Higher than normal ... Thom, Steven R (1992). "Inert gas enhancement of superoxide radical production". Archives of Biochemistry and Biophysics. 295 ( ...
*  Cat cognitive support diets
Manganese functions as a co-factor for another form of superoxide dismutase (Mn-SOD) that is only found within mitochondria, ... Webb, Craig B.; Lehman, Tracy L.; McCord, Kelly W. (October 2008). "Effects of an oral superoxide dismutase enzyme ... Zinc and copper are co-factors for superoxide dismutase to form Cu-Zn-SOD, an antioxidant enzyme that catalyzes the breakdown ... of superoxide radical into normal oxygen molecules or hydrogen peroxide by adding or removing an electron. A study by Webb et ...
*  Molecular graphics
Three-dimensional structure of Cu, Zn superoxide dismutase. Superoxide and superoxide disumases. Ed. By A.M. Michelson, J.M. ... The Richardson group published partial atomic structure results of the protein superoxide dismutase the same year, in 1977. All ...
*  Iron oxide
The enzyme superoxide dismutase can also catalyze this reaction. Once H₂O₂ has been synthesized, it can diffuse through ... O₂ + e⁻ → O₂•⁻ The formation of the superoxide anion (O₂•⁻) is catalyzed by a transmembrane enzyme called NADPH oxidase. The ...
*  Protandim
CMX-1152 was claimed to upregulate the production of the endogenous antioxidant enzymes superoxide dismutase, catalase, and ... Robbins, Delira; Zhao, Yunfeng (2011). "The Role of Manganese Superoxide Dismutase in Skin Cancer". Enzyme Research. 2011: 1-7 ... "The induction of human superoxide dismutase and catalase in vivo: A fundamentally new approach to antioxidant therapy". Free ... supplement that increases the body's antioxidant defenses by upregulating superoxide dismutase, catalase, and glutathione ...
*  Senescence
Superoxide dismutase, a protein that protects against the effects of mitochondrial free radicals, can extend yeast lifespan in ... Under normal aerobic conditions, approximately 4% of the oxygen metabolized by mitochondria is converted to superoxide ion, ...
*  QPNC-PAGE
Therefore, copper chaperone for superoxide dismutase is proposed to be one of the most promising biomarkers of Cu toxicity in ... Youn HD, Kim EJ, Roe JH, Hah YC, Kang SO (1996). "A novel nickel-containing superoxide dismutase from Streptomyces spp". ... Gray EH, De Vos KJ, Dingwall C, Perkinton MS, Miller CC (2010). "Deficiency of the copper chaperone for superoxide dismutase ... Improperly folded metal proteins, for example, CCS or Cu/Zn-superoxide dismutase (SOD1) present in brain, blood or other ...