... is molecularly similar to serotonin (5-HT), and is a 5-HT receptor (types 5-HT1D and 5-HT1B) agonist. Sumatriptan's ... Injected sumatriptan is more effective than other formulations. Oral sumatriptan can be used also in the treatment of post- ... When injected, sumatriptan is faster-acting (usually within 10 minutes), but the effect lasts for a shorter time. Sumatriptan ... Sumatriptan is also shown to decrease the activity of the trigeminal nerve, which presumably accounts for sumatriptan's ...
Comparison with placebo and oral sumatriptan". Functional Neurology. 15 (Suppl 3): 196-201. PMID 11200792. Zhao Y, Shen LH, ... lysine acetylsalicylate has comparable efficacy to sumatriptan for migraine. Clinical trials on the use of lysine ...
Zecuity, a sumatriptan transdermal patch, was approved by the US FDA in January 2013. The sumatriptan nasal powder was approved ... Sumatriptan and zolmitriptan are also available as nasal sprays. For sumatriptan, a number of other application forms are ... Comparison of sumatriptan and dihydroergotamine showed that dihydroergotamine has high affinity and sumatriptan has medium ... In studies, newer triptans are mostly compared to sumatriptan. They are better than sumatriptan for their longer half-life in ...
Arora A, Arora S (September 2006). "Spontaneous splenic infarction associated with sumatriptan use". J Headache Pain. 7 (4): ... sumatriptan or bevacizumab. In a single-center retrospective cases review, people who were admitted to the hospital with a ...
A third Migraleve variant, Migraleve Ultra, contains sumatriptan. The pink tablet is supposed to be taken before the yellow ... The active ingredient of Migraleve Ultra is 50 mg sumatriptan, similar to Imigran recovery. The Product Licence Holder is: ...
A schematic drawing of the binding of sumatriptan to 5-HT1D receptor can be seen in figure 4. One study showed that sumatriptan ... The sumatriptan nasal spray provides faster onset of action than the tablets but it produces a similar headache response at 2 ... Sumatriptan was first launched in the Netherlands in 1991 and became available in the United States during 1993. Triptans are ... The U.S. Food and Drug Administration (FDA) approved a new drug April 15, 2008, which is a combination of sumatriptan 85 mg and ...
Therapeutic treatment for the prodromal phase, characterized by the anticipation of an episode, consists of sumatriptan (nasal ... "Adult Cyclic Vomiting Syndrome Successfully Treated with Intranasal Sumatriptan". Journal of General Internal Medicine. 25 (1 ...
Sumatriptan and zolmitriptan have both been shown to improve symptoms during an attack with sumatriptan being superior. Because ... Valproate, sumatriptan, and oxygen are not recommended as preventive measures. Botulinum toxin injections have shown limited ... The hallucinogen DMT has a chemical structure that is similar to the triptan sumatriptan, indicating a possible shared ... The other primarily recommended treatment of acute attacks is subcutaneous or intranasal sumatriptan. ...
This finding provided an incentive for the development of sumatriptan. Novartis withdrew it from the U.S. market after taking ... Dahlöf C, Maassen Van Den Brink A (April 2012). "Dihydroergotamine, ergotamine, methysergide and sumatriptan - basic science in ...
Subcutaneous sumatriptan autoinjectors are used to terminate cluster headache attacks. Naloxone autoinjectors are being ...
Several antimigraine drugs, available by the trade names of Imitrex- sumatriptan; Zomig - Zolmitriptan; Migranal - ...
Triptans such as sumatriptan are effective for both pain and nausea in up to 75% of migraineurs. They are the initially ... as PDF Archived 2010-03-31 at the Wayback Machine Derry, Christopher J.; Derry, Sheena; Moore, R Andrew (2012). "Sumatriptan ( ...
Further clinical studies of intranasal administration of sumatriptan (ST) can help evaluate efficacy and safety of such ... A nasal spray containing sumatriptan demonstrated a significant reduction of migraine pain. ... "Harnessing Intranasal Delivery Systems of Sumatriptan for the Treatment of Migraine". BioMed Research International. 2022: ...
Ogunyemi, A; Adams, D (May 1998). "Migraine-like symptoms triggered by occipital lobe seizures: response to sumatriptan". The ...
Triptans such as sumatriptan are medications used to stop an active migraine headache (an abortive medication). Triptans are ... Sumatriptan does not prevent other migraine headaches from starting in the future. For increased effectiveness at stopping ... Some people may find that they respond to one type of sumatriptan better than another. Most side effects are mild, including ... Law S, Derry S, Moore RA (April 2016). "Sumatriptan plus naproxen for the treatment of acute migraine attacks in adults". The ...
This includes methotrexate for juvenile idiopathic arthritis and sumatriptan for treatment of migraines. Most injector pens are ... "Subcutaneous sumatriptan delivery devices: comparative ease of use and preference among migraineurs". Patient Preference and ...
Drugs involving succinate include metoprolol succinate, sumatriptan succinate, Doxylamine succinate or solifenacin succinate.[ ...
Amital D, Fostick L, Sasson Y, Kindler S, Amital H, Zohar J (May 2005). "Anxiogenic effects of Sumatriptan in panic disorder: a ...
A 2010 review found rizatriptan to be more efficacious and tolerable than sumatriptan. Rizatriptan and other triptans can cause ... Göbel H (2010). "Efficacy and tolerability of rizatriptan 10 mg compared with sumatriptan 100 mg: an evidence-based analysis". ... Like the other triptans sumatriptan and zolmitriptan, rizatriptan induces vasoconstriction-possibly by inhibiting the release ...
It is a derivative of the migraine medication sumatriptan, but while CP-122,288 is 40,000 times more potent than sumatriptan as ... Waeber C, Moskowitz MA (September 1995). "[3H]sumatriptan labels both 5-HT1D and 5-HT1F receptor binding sites in the guinea ... 5-MeO-MPMI CP-135807 Eletriptan Lee WS, Moskowitz MA (October 1993). "Conformationally restricted sumatriptan analogues, CP- ... a conformationally restricted analogue of sumatriptan". European Journal of Pharmacology. 276 (3): 271-6. doi:10.1016/0014-2999 ...
Shaat, Ahmed Mohamed; Abdalgaleil, Mohamed Mahmoud (2021-01-01). "Is theophylline more effective than sumatriptan in the ...
Fanciullacci M, Sicuteri R, Alessandri M, Geppetti P (March 1995). "Buspirone, but not sumatriptan, induces miosis in humans: ...
Russia - Classified as a Schedule I narcotic, including its derivatives (see sumatriptan and zolmitriptan). Serbia - DMT, along ...
Triptans such as sumatriptan, rizatriptan, and naratriptan are 5-HT1B receptor agonists that are used to abort migraine and ... Triptans such as eletriptan, naratriptan, and sumatriptan are agonists of the 5-HT1F receptor. Lasmiditan is a selective 5-HT1F ... In addition to being 5-HT1B agonists, triptans (i.e. sumatriptan, almotriptan, zolmitriptan, naratriptan, eletriptan, ...
... was shown not to interact with ethinylestradiol, norgestimate or the migraine drug sumatriptan. It is expected to ...
Many synthetic tryptamines have also been made, including the migraine drug sumatriptan, and psychedelic drugs. A 2022 study ...
Cohen ML, Schenck K, Nelson D, Robertson DW (January 1992). "Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D ... 5-Carboxamidotryptamine 5-Methoxytryptamine BW-723C86 Sumatriptan Lyon RA, Titeler M, Seggel MR, Glennon RA (January 1988). " ...
The triptan drug class includes 1st generation sumatriptan (which has poor bioavailability), and second generation zolmitriptan ...
Abortive therapy for cluster headaches includes subcutaneous sumatriptan (injected under the skin) and triptan nasal sprays. ...
Bouchelet I, Cohen Z, Case B, Séguéla P, Hamel E (Aug 1996). "Differential expression of sumatriptan-sensitive 5- ... Oxymetazoline Sumatriptan (vasoconstrictor in migraine) Zolmitriptan 5-Carboxamidotryptamine CGS-12066A CP-93,129 (peripherally ...