Sulindac
... is much more likely than other NSAIDs to cause damage to the liver or pancreas, though it is less likely to cause ... Sulindac is a prodrug, derived from sulfinylindene, that is converted in the body to the active NSAID. More specifically, the ... Sulindac seems to have a property, independent of COX-inhibition, of reducing the growth of polyps and precancerous lesions in ... Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed as Clinoril. Imbaral ...
Analgesic
"Aclin Sulindac" (PDF). TGA eBusiness Services. Alphapharm Pty Limited. 8 November 2011. Archived from the original on 15 ...
Malcolm VandenBurg
Hayes, TB; Fyvie, A; Janke, PG; Vandenburg, MJ; Currie, WJ (March 1984). "Sulindac versus ibuprofen in sprains and strains". ...
Exisulind
Sulindac "Exisulind: Aptosyn, FGN 1, Prevatac, sulindac sulfone". Drugs in R&D. 5 (4): 220-6. 2004. doi:10.2165/00126839- ... It is the sulfone derivative of sulindac, an NSAID. Unlike sulindac, it has known effects on prostaglandin synthesis. It was ... Sulindac Sulfone, FGN-1) as a chemopreventive agent in patients with familial adenomatous polyposis". Clinical Cancer Research ... "Inhibition of Angiogenesis by Sulindac and its Sulfone Metabolite (FGN-1): a Potential Mechanism for Their Antineoplastic ...
Pharmacomicrobiomics
Strong, HA; Renwick, AG; George, CF; Liu, YF; Hill, MJ (1987). "The reduction of sulphinpyrazone and sulindac by intestinal ... Strong, HA; Renwick, AG; George, CF; Liu, YF; Hill, MJ (1987). "The reduction of sulphinpyrazone and sulindac by intestinal ...
Flavin-containing monooxygenase
Hamman MA, Haehner-Daniels BD, Wrighton SA, Rettie AE, Hall SD (July 2000). "Stereoselective sulfoxidation of sulindac sulfide ...
Familial adenomatous polyposis
Another investigational agent is sulindac, also used in combination with NSAIDs. Prior to reaching the advanced stages of ... "Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis". New England Journal of Medicine. ... sulindac combination therapy versus each as monotherapy in patients with familial adenomatous polyposis (FAP): design and ...
Essential fatty acid
"Tissue prostaglandin levels in familial adenomatous polyposis patients treated with sulindac". Diseases of the Colon and Rectum ...
Herbert Weissbach (biochemist)
Weissbach, H (2009). "Sulindac confers high level ischemic protection to the heart through late preconditioning mechanisms". ... Weissbach, H (2012). "Combination of Sulindac and Dichloroacetate Kills Cancer Cells via Oxidative Damage". PLOS ONE. 7 (7): ... Weissbach, H (2014). "Pharmacological protection of retinal pigmented epithelial cells by sulindac involves PPARα". Proceedings ...
Hepatotoxicity
... sulindac, phenylbutazone, piroxicam, diclofenac and indomethacin. Glucocorticoids are so named due to their effect on the ...
Thalidomide
"Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits". British Journal of ...
Immunomodulatory imide drug
"Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits". Br. J. Cancer. 79 (1 ...
Flavin-containing monooxygenase 3
... tamoxifen and sulindac sulfide; and agrichemicals, such as organophosphates and carbamates [14-22]. Cashman JR (September 2000 ...
Mutual Pharmaceutical Co. v. Bartlett
In 1978 the FDA approved an anti-inflammatory pain reliever called sulindac under the brand name Clinoril. When the patent ...
Tocolytic
"Fetal cardiac function and ductus arteriosus during indomethacin and sulindac therapy for threatened preterm labor: A ...
Caesarean section
"High perinatal survival in monoamniotic twins managed by prophylactic sulindac, intensive ultrasound surveillance, and Cesarean ...
Monoamniotic twins
Sulindac has been used experimentally in some monoamniotic twins, lowering the amount of amniotic fluid and thereby inhibiting ...
Apc, wnt signaling pathway regulator
... and oral sulindac treatment in the colon and rectum of patients with familial adenomatous polyposis". Dis. Colon Rectum. 44 (8 ...
Fundic gland polyposis
Esaki, M; Matsumoto, T; Mizuno, M; Kobori, Y; Yoshimura, R; Yao, T; Iida, M (2002). "Effect of sulindac treatment for ...
Personalized onco-genomics
A second round of RET inhibitors (sorafenib and sulindac) administration provided an additional 3 months of disease ...
Indometacin
For patients taking lithium (e.g. for treatment of depression or bipolar disorder), less toxic NSAIDs such as sulindac or ...
Indene
... such as sulindac. Indene occurs naturally in coal-tar fractions boiling around 175-185 °C. It can be obtained by heating this ...
ATC code M01
M01AA05 Clofezone M01AA06 Kebuzone QM01AA90 Suxibuzone QM01AA99 Combinations M01AB01 Indometacin M01AB02 Sulindac M01AB03 ...
Cholestasis
... sulindac, chlorpromazine, erythromycin, prochlorperazine, cimetidine, estrogen, and statins can cause cholestasis and may ...
Flurbiprofen
... and sulindac.: 34 It was patented in 1964 by Boots UK and approved for medical use in 1987. It was approved in the US in 1988; ...
Nonsteroidal anti-inflammatory drug
Oxaprozin Loxoprofen Pelubiprofen Zaltoprofen Fenbufen Tiaprofenic acid Carprofen Indomethacin Acemetacin Tolmetin Sulindac ...
Index of oncology articles
... sulindac - superior vena cava - superior vena cava syndrome - supraclavicular lymph node - supraglottic laryngectomy - ...
List of drugs: Suc-Sul
... sulindac (INN) sulisatin (INN) sulisobenzone (INN) sulla sulmarin (INN) sulmazole (INN) sulmepride (INN) Sulmeprim sulnidazole ...
List of MeSH codes (D04)
... sulindac MeSH D04.615.562.050 - anthracyclines MeSH D04.615.562.050.050 - aclarubicin MeSH D04.615.562.050.200 - daunorubicin ...