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*  Thiol S-methyltransferase
Bremer J; Greenberg DM (1961). "Enzymic methylation of foreign sulfhydryl compounds". Biochim. Biophys. Acta. 46 (2): 217-224. ...
*  Tiopronin
Jaffe, Israeli A. (March 1986). "Adverse effects profile of sulfhydryl compounds in man". The American Journal of Medicine. 80 ... which are broadly similar to those of D-penicillamine and other compounds containing active sulfhydryl groups. Its ...
*  SLC26A2
2003). "In vitro proteoglycan sulfation derived from sulfhydryl compounds in sulfate transporter chondrodysplasias". Pediatr ...
*  Johanna Budwig
Budwig believed sulphydryl compounds were important to cellular metabolism and cellular respiration. Budwig researched the ... theory that a low oxygen environment would develop in the absence of sulphydryl groups and/or fatty acid partners that would ... a researcher at the German Federal Health Office she noted many cancer drugs being evaluated in the 1950s contained sulphydryl ...
*  Cell cycle
The pattern of resistance and sensitivity correlates with the level of sulfhydryl compounds in the cell. Sulfhydryls are ... The deciding factor is availability of nitrogens and storage of energy rich compounds at the deciding point called check point ...
*  Cinitapride
... prostaglandins and sulfhydryl compounds". Pharmacology. 54 (4): 193-202. doi:10.1159/000139487. PMID 9211565. Alarcón de la ...
*  Isosorbide mononitrate
Sulfhydryl-containing compounds. The metabolism of organic nitrates to nitric oxide is dependent on the presence of sulfhydryl ... Concomitant administration of other exogenous sources of sulfhydryl groups such as methionine and captopril may produce a ...
*  Glutathione
Jara JR, Aroca P, Solano F, Martinez JH, Lozano JA (November 1988). "The role of sulfhydryl compounds in mammalian ... The sulfhydryl group (SH) of cysteine serves as a proton donor and is responsible for its biological activity. Cysteine is the ... Additionally, compounds such as N-acetylcysteine (NAC) and alpha lipoic acid (ALA, not to be confused with the unrelated alpha- ... An exception to this case involves the sensitivity of GSH to the electrophilic compound's relative concentration. In high ...
*  Cystinuria
... lysine and ornithine in relation to genetic findings in patients with cystinuria treated with sulfhydryl compounds". Urological ...
*  Methacrylonitrile
For example via epoxide hydratase (EH) or via interactions with a sulfhydryl compound, which leads to the formation of a ... Methacrylonitrile (or 2-Methylprop-2-enenitrile), MeAN in short, is a chemical compound that is an unsaturated aliphatic ... "unsaturated compounds formed by a burning cigarette. Anal. Proc. 21, 135 Farooqui, M. Y. H. and M. M. Mumtaz (1991). " ...
*  Thiosalicylic acid
... is an organosulfur compound containing carboxyl and sulfhydryl functional groups. Its molecular formula is ...
*  2-Iminothiolane
... reacts witih primary amines efficienty at pH 7 to 9, creating aminidine compounds with a sulfhydryl group. Thus ... It is a thiolating reagent that reacts with primary amine groups, such as those of amino acids, to form sulfhydryl groups. ... 2-Iminothiolane is a cyclic thioimidate compound also known as Traut's reagent. ...
*  Ulcerative colitis
Compounds that contain sulfhydryl may have an effect in ulcerative colitis (under a similar hypothesis that the sulfa moiety of ... Since then, many 5-ASA compounds have been developed with the aim of maintaining efficacy but reducing the common side effects ... Salim AS (1992). "Role of sulphydryl-containing agents in the management of recurrent attacks of ulcerative colitis. A new ...
*  Mesna
... is a organosulfur compound. It works by altering the breakdown products of cyclophosphamide and ifosfamide found in the ... Mesna assists to detoxify these metabolites by reaction of its sulfhydryl group with α,β-unsaturated carbonyl containing ... Mesna reduces the toxicity of urotoxic compounds that may form after chemotherapy administration. Mesna is a water-soluble ... This conjugation reaction inactivates the urotoxic compounds to harmless metabolites. The metabolites are then excreted in the ...
*  Acetylcholine
Organic mercurial compounds, such as methylmercury, have a high affinity for sulfhydryl groups, which causes dysfunction of the ... Acetylcholine is synthesized in certain neurons by the enzyme choline acetyltransferase from the compounds choline and acetyl- ... muscarine is a compound found in the mushroom Amanita muscaria; nicotine is found in tobacco. Nicotinic acetylcholine receptors ...
*  Moexipril
A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types". Journal of Medicinal Chemistry. 29 ( ... and is metabolized in the liver to form the pharmacologically active compound moexiprilat. Formation of moexiprilat is caused ... "Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. ...
*  Branched-chain amino acid aminotransferase
... sulfhydryl, or Cu2+ or Co2+ reagents/compounds Enzyme catalyzes reaction best with branched chain amino acids (in order from ... In Cucumis melo (melon), BCATs have been found to play a role in developing aroma volatile compounds that give melons their ... As fermentation proceeds, these α-ketoacids degrade into a class of compounds known as methyl-branched volatiles that include ... The branched-chain amino acid aminotransferases help to produce compounds like isovaleric acid, isobutyric acid, 2- and 3- ...
*  Thiophenol
... s also describes a class of compounds formally derived from thiophenol itself. All have a sulfhydryl group (-SH) ... The prefix thio- implies a sulfur-containing compound and when used before a root word name for a compound which would normally ... Thiophenol is an organosulfur compound with the formula C6H5SH, sometimes abbreviated as PhSH. This foul-smelling colourless ... There are several methods of synthesis for thiophenol and related compounds, although thiophenol itself is usually purchased ...
*  Thiol
In organic chemistry, a thiol (/ˈθaɪɔːl/, /ˈθaɪɒl/) is an organosulfur compound that contains a carbon-bonded sulfhydryl (R-SH ... These compounds are detectable by the human nose at concentrations of only 10 parts per billion. Human sweat contains (R)/(S)-3 ... Sulfhydryl groups in the active site of an enzyme can form noncovalent bonds with the enzyme's substrate as well, contributing ... The effect of the latter compound is present only at low concentrations. The pure mercaptan has an unpleasant odor. Natural gas ...
*  Pan-assay interference compounds
... chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS". ... Pan-assay interference compounds, also referred to as PAINS in the assay or simply PAINS, are chemical compounds that are often ... Baell JB, Holloway GA (April 2010). "New substructure filters for removal of pan assay interference compounds (PAINS) from ... the accuracy of filters with regard to compounds they flag and don't flag has been criticized. Drug discovery Dahlin JL, ...
*  Arsenic biochemistry
However, the monomethylated compound was shown to be more reactive and more toxic than the inorganic arsenic compounds to human ... Enzymes and receptors that contain thiol or sulfhydryl functional groups are actively targeted by arsenite (III) metabolites. ... This compound is then converted to a mono-methylated arsenic (III) compound using Glutathione S-Transferase Omega-1 (GSTO1). ... Representative organoarsenic compounds found in nature. Arsenobetaine, one of the most common arsenic compound in nature. Also ...
*  Miguel Ondetti
He settled on using a sulfhydryl group which binds strongly to zinc. Ondetti had discovered Captopril, an ACE inhibitor with ... U.S. Patent 3,740,385 "N-Terminal Derivatives of Secretin", filed May 1970, issued June 1973 U.S. Patent 4,199,512 "Compounds ... "Compounds for alleviating angiotensin related hypertension", filed February 1978, issued July 1982 U.S. Patent 4,722,810 " ... His group tried thousands of compounds from the Squibb library, but none yielded satisfying results. After reading literature ...
*  Glutathione S-transferase
... of GSH-via a sulfhydryl group-to electrophilic centers on a wide variety of substrates in order to make the compounds more ... However, some endogenous compounds, e.g., bilirubin, can inhibit the activity of GSTs. In mammals, GST isoforms have cell ... The compounds targeted in this manner by GSTs encompass a diverse range of environmental or otherwise exogenous toxins, ... Because the GST protein has a strong binding affinity for GSH, beads coated with the compound can be added to the protein ...
*  Butanethiol
... is a very noxious and caustic chemical compound, and at sufficiently high concentrations, it produces serious ... except that sulfur-containing sulfhydryl group (-SH) replaces the oxygen-containing hydroxyl group (-OH) in the molecule. ... which are organic compounds with molecular formulas and structural formulas similar to alcohols, ...
*  Propanethiol
... is an organic compound with the molecular formula C3H8S. It belongs to the group of thiols. It is a colorless ... except that sulfur-containing sulfhydryl group (-SH) replaces the oxygen-containing hydroxyl group in the molecule. ... Propanethiol is chemically classified among the thiols, which are organic compounds with molecular formulas and structural ...