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*  Walker motifs
Implications for substrate specificity". J. Biol. Chem. 273 (34): 21714-20. doi:10.1074/jbc.273.34.21714. PMID 9705307. ... and is also found in a variety of proteins with phosphorylated substrates. These include ATP synthase (α and β subunits), ...
*  PNGase F
Multiplicity and substrate specificity". Biochimica et Biophysica Acta. 657 (2): 457-67. doi:10.1016/0005-2744(81)90331-4. PMID ... Tachibana Y, Yamashita K, Kobata A (1982). "Substrate specificity of mammalian endo-beta-N-acetylglucosaminidase: study with ... PNGase F lacks selectivity for outer carbohydrate structure, resulting in broad specificity, making it a useful tool for ... These endoglycosidases have more specificity in cleavage and are less sensitive to protein conformation than PNGase F. All of ...
*  ACP1
Implications for substrate specificity". J. Biol. Chem. 273 (34): 21714-20. doi:10.1074/jbc.273.34.21714. PMID 9705307. Tailor ...
*  Violaxanthin de-epoxidase
Goss, R. (2003). "Substrate specificity of the violaxanthin de-epoxidase of the primitive green alga Mantoniella squamata ( ... Lipid composition and substrate specificity". Arch. Biochem. Biophys. 190 (2): 514-522. doi:10.1016/0003-9861(78)90305-3. PMID ...
*  Strictosidine synthase
... the enzyme possesses a high degree of substrate specificity, with the indole moiety of tryptamine required for substrate ... McCoy E, Galan MC, O'Connor SE (2006). "Substrate specificity of strictosidine synthase". Bioorg. Med. Chem. Lett. 16 (9): 2475 ... have suggested that strictosidine synthase can be easily manipulated to have a broader range of substrate specificity. For ... Upon substrate binding, secologanin's position is located at the pocket's entrance, where the positively charged residues His ...
*  EPHX1
... has broad substrate specificity. EPHX1 detoxifies low molecular weight chemicals, e.g., butadiene, benzene, styrene, etc ... Oesch F (1974). "Purification and specificity of a human microsomal epoxide hydratase". Biochem. J. 139 (1): 77-88. doi:10.1042 ... Androstene oxide and epoxyestratrienol have been shown as endogenous EPHX1 substrates. EPHX1 also metabolizes endocannabinoid 2 ... Structure-activity relationships for substrates and inhibitors". Biochemistry. 10 (26): 4858-66. doi:10.1021/bi00802a005. PMID ...
*  Tryptophan alpha,beta-oxidase
Substrate specificity and mechanistic implications". J. Biol. Chem. 270 (40): 23540-5. doi:10.1074/jbc.270.40.23540. PMID ... the two substrates of this enzyme are L-tryptophan and O2, whereas its two products are alpha,beta-didehydrotryptophan and H2O2 ...
*  OGT (gene)
Domain structure and substrate specificity". The Journal of Biological Chemistry. 275 (15): 10983-8. doi:10.1074/jbc.275.15. ... or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains 9 or 14 ... Whelan SA, Dias WB, Thiruneelakantapillai L, Lane MD, Hart GW (Feb 2010). "Regulation of insulin receptor substrate 1 (IRS-1)/ ... but the structure of a binary complex with UDP and a ternary complex with UDP and a peptide substrate has been researched. The ...
*  ALPPL2
Implication for a substrate specificity". The Journal of Biological Chemistry. 276 (12): 9158-65. doi:10.1074/jbc.M009250200. ...
*  Haloalkane dehalogenase
Koudelakova T, Chovancova E, Brezovsky J, Monincova M, Fortova A, Jarkovsky J, Damborsky J (2011). "Substrate Specificity of ... To begin, aspartate 124 is perfectly aligned with the substrate. It will drive off the halogen and form an ester functionality ... the two substrates of this enzyme are 1-haloalkane and H2O, whereas its two products are primary alcohol and halide. This ... a dehalogenase of wide substrate range from an Arthrobacter sp". J. Bacteriol. 169 (11): 5016-21. PMC 213902 . PMID 3667524. ...
*  Trypanothione-disulfide reductase
Marsh IR, Bradley M (1997). "Substrate specificity of trypanothione reductase". Eur. J. Biochem. 243 (3): 690-4. doi:10.1111/j. ... the two substrates of this enzyme are trypanothione and NADP+, whereas its 3 products are trypanothione disulfide, NADPH, and ... Subversive Substrates and Antitrypanosomal Properties". ChemMedChem. 2 (12): 1708-12. doi:10.1002/cmdc.200700172. PMID 17918760 ...
*  Robert K. Crane
"Substrate specificity of brain hexokinase". Journal of Biological Chemistry 210, 1954, pp. 581-595. Robert K. Crane, Richard A ...
*  Fructose-bisphosphate aldolase)-lysine N-methyltransferase
"Polypeptide substrate specificity of PsLSMT. A set domain protein methyltransferase". J. Biol. Chem. 282: 27857-27864. doi: ...
*  Placental alkaline phosphatase
Implication for a substrate specificity". J. Biol. Chem. 276 (12): 9158-65. doi:10.1074/jbc.M009250200. PMID 11124260. Spurway ... substrate proteins associate with the transamidase subunit gpi8p". J. Biol. Chem. 276 (19): 15975-82. doi:10.1074/jbc. ...
*  ADH7
Structural basis for substrate specificity". The Journal of Biological Chemistry. 272 (30): 18558-63. doi:10.1074/jbc.272.30. ... Active-site amino acid sequence explains substrate specificity compared with liver isozymes". The Journal of Biological ... Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, ...
*  Riboflavin kinase
McCormick DB; Butler RC (1962). "Substrate specificity of liver flavokinase". Biochim. Biophys. Acta. 65 (2): 326-332. doi: ... the two substrates of this enzyme are ATP and riboflavin, whereas its two products are ADP and FMN. Riboflavin is converted ...
*  Estradiol 17beta-dehydrogenase
Kinetics and substrate specificities". J. Biol. Chem. 234: 2609-14. PMID 14413943. Molecular and Cellular Biology portal. ... H+ The 3 substrates of this enzyme are estradiol-17beta, NAD+, and NADP+, whereas its 4 products are estrone, NADH, NADPH, and ...
*  ADAM33
Zou J, Zhang R, Zhu F, Liu J, Madison V, Umland SP (March 2005). "ADAM33 enzyme properties and substrate specificity". ...
*  Tripeptide aminopeptidase
Substrate specificity and effects of inhibitors". Biochim. Biophys. Acta. 706: 229-238. doi:10.1016/0167-4838(82)90491-5. PMID ...
*  Amine oxidase (copper-containing)
I. Substrate specificity and electrophoresis studies". Biochem. J. 71 (3): 477-84. PMC 1196820 . PMID 13638253. Boyer, P.D., ... "Kinetic and structural analysis of substrate specificity in two copper amine oxidases from Hansenula polymorpha". Biochemistry ... The active site is buried and requires a conformational change to allow the substrate access. The N2 and N3 N-terminal domains ... In prokaryotes, the enzyme enables various amine substrates to be used as sources of carbon and nitrogen. This enzyme belongs ...
*  Carboxypeptidase A6
Lyons, P. J.; Fricker, L. D. (2010). "Substrate Specificity of Human Carboxypeptidase A6". Journal of Biological Chemistry. 285 ... CPA6 may have additional roles in processing peptides and proteins in vivo, but the nature of these substrates and the effects ...
*  Arylesterase
I. Substrate specificity and electrophoresis studies". Biochem. J. 71 (3): 477-84. PMC 1196820 . PMID 13638253. Bosmann HB ( ... are lactonases with overlapping and distinct substrate specificities". J. Lipid Res. 46: 1239-47. doi:10.1194/jlr.M400511- ... are lactonases with overlapping and distinct substrate specificities". The Journal of Lipid Research. 46: 1239-1247. doi: ... Characterization of an arylesterase of guinea pig cerebral cortex utilizing p-nitrophenyl acetate as substrate". Biochim. ...
*  Isopenicillin N synthase
Retrieved from Encyclopædia Britannica Online: [1] Miller FD, Chapman JL, Queener SW (1992). "Substrate specificity of ... This allows for the binding of the substrate ACV to the deprotonated thiol group of the cysteine residue. This ligation of the ... and two water molecules in the absence of a bound substrate. Just two histidine residues and one aspartic acid residue are ... "Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation". Nature. 387 (6635): ...
*  Ribosylpyrimidine nucleosidase
Substrate specificity, gene expression, and regulation". J. Biol. Chem. 276 (2): 884-94. doi:10.1074/jbc.M008300200. PMID ... the two substrates of this enzyme are pyrimidine nucleoside and H2O, whereas its two products are D-ribose and pyrimidine base ...
*  Ricinine nitrilase
I. REACTION PRODUCT AND SUBSTRATE SPECIFICITY". J. Biol. Chem. 239: 4257-62. PMID 14247679. HOOK RH, ROBINSON WG (1964). " ... the two substrates of this enzyme are ricinine and H2O, whereas its two products are 3-carboxy-4-methoxy-N-methyl-2-pyridone ...
*  UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase
"Acyl chain specificity of the acyltransferases LpxA and LpxD and substrate availability contribute to lipid A fatty acid ...