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*  Directed differentiation
co-culture with stromal cells or feeder cells, and on specific culture substrates: support cells and matrices provide ... introduced in the cells. The starting material can be either pluripotent stem cells (PSCs), or either differentiated cell type ... human immortalized cells or primary cultures from biopsies, which their limitations. Clinically-relevant cell types i.e. cell ... "Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells". The Journal of Cell Biology. ...
*  Stroma of cornea
Stromal transparency is mainly a consequence of the remarkable degree of order in the arrangement of the collagen fibrils in ... Apart from the cells, the major non-aqueous constituents of the stroma are collagen fibrils and proteoglycans. The collagen ... Branch MJ, Hashmani K, Dhillon P, Jones DR, Dua HS, Hopkinson A (Aug 3, 2012). "Mesenchymal stem cells in the human corneal ... The lamellæ are produced by keratocytes (corneal connective tissue cells), which occupy about 10% of the substantia propria. ...
*  Stromal cell
Fibroblasts and pericytes are among the most common types of stromal cells. The interaction between stromal cells and tumor ... bone marrow stromal cells have been described to be involved in human haematopoiesis and inflammatory processes. Stromal cells ... Stromal cells are connective tissue cells of any organ, for example in the uterine mucosa (endometrium), prostate, bone marrow ... cannot spread throughout the body because the cancer cells require nearby stromal cells to continue their division. The loss of ...
*  Lymph node stromal cell
... dendritic cells move to the T cell zone or to the B cell follicle along the fibroblast reticular cell network. Dendritic cells ... Most lymph node stromal cells preferentially express DF1, an Aire-like transcription modulator. Lymph node stromal cells can be ... Stromal cells originate from multipotent mesenchymal stem cells. Lymph nodes are enclosed in an external fibrous capsule and ... Lymph node stromal cells can give rise to a number of malignancies including: follicular dendritic cell sarcoma; fibroblastic ...
*  Stromal cell-derived factor
There are several stromal cell derived factors: Stromal cell-derived factor-1 (SDF-1, SDF1, Sdf1) Stromal cell-derived factor-1 ... Stromal cell-derived factor-2 (SDF-2, SDF2, Sdf2) Stromal cell-derived factor-3 (SDF-3, SDF3, Sdf3) Stromal cell-derived factor ...
*  Stromal cell-derived factor 1
It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small ... Zheng H, Fu G, Dai T, Huang H (2007). "Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha ... Stellos K, Gawaz M (March 2007). "Platelets and stromal cell-derived factor-1 in progenitor cell recruitment". Seminars in ... "Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy". Lancet. 362 ( ...
*  GPR126
... is all widely expressed on stromal cells. The N-terminal fragment of GPR126 contains C1r-C1s, Uegf and Bmp1 (CUB), and ... Mogha A, Benesh AE, Patra C, Engel FB, Schöneberg T, Liebscher I, Monk KR (Nov 2013). "Gpr126 functions in Schwann cells to ... Forced GPR126 expression in COS-7 cells enhances cAMP levels by coupling to heterotrimeric Gαs/i proteins. GPR126 has been ... Upon lipopolysaccharide (LPS) or thrombin stimulation, expression of GPR126 is induced by MAP kinases in endothelial cells. ...
*  Stem cell secretome
The stem cell secretome, (also referred to as the stromal cell secretome), is a collective term for the paracrine soluble ... stem cell factor (SCF), granulocyte colony-stimulating factor (G-CSF) and stromal cell-derived factor (SDF-1) both in vitro and ... "The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration". Cytotherapy. 18 (1 ... "Secretome of mesenchymal stem/stromal cells in regenerative medicine". Biochimie. Special section : The Mesenchymal Stem Cell ...
*  Vaginal adenosis
... epithelial and stromal cells in vaginal adenosis show characteristic fusion through the basal lamina or with stromal ... Roberts, Daniel K.; Walker, Nola J.; Parmley, Tim H.; Horbelt, Douglas V. (1988). "Interaction of epithelial and stromal cells ... Its mucinous cells resemble the normal cervical lining, while its tuboendometrial cells resemble the lining of normal fallopian ... Association with clear cell adenocarcinoma in diethylstilbestrol-exposed offspring". Cancer. 54 (5): 869-875. doi:10.1002/1097- ...
*  Stroma (tissue)
Stromal tissue falls into the functional class that contributes to the body's support and movement. The cells which make up ... immune system blood cells causing inflammatory response. Fixed cells - cells that are permanent inhabitants of the tissue. ... Stroma is made of various types of stromal cells. Examples of stroma include: stroma of iris stroma of cornea stroma of ovary ... Stromal tissue is primarily made of extracellular matrix containing connective tissue cells. Extracellular matrix is primarily ...
*  Mir-193 microRNA precursor family
Cismasiu, V. B.; Radu, E.; Popescu, L. M. (2011). "MiR-193 expression differentiates telocytes from other stromal cells". ... Stem Cells and Development. 21 (13): 2508-2519. doi:10.1089/scd.2011.0695. PMC 3424971 . PMID 22384930. ... "MicroRNA-193 Pro-Proliferation Effects for Bone Mesenchymal Stem Cells After Low-Level Laser Irradiation Treatment Through ...
*  Voltage-dependent anion channel
"The Cell Surface Proteome of Human Mesenchymal Stromal Cells". PLoS ONE. 6 (5): e20399. doi:10.1371/journal.pone.0020399. PMC ... and role in mitochondrial function in cell life and death". Cell Biochem. Biophys. 39 (3): 279-92. doi:10.1385/CBB:39:3:279. ... "Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells". J. Cell Biol. 152 (2): 237 ... There is debate as to whether or not this channel is expressed in the cell surface membrane. This major protein of the outer ...
*  Vemurafenib
Stromal cell secretion of hepatocyte growth factor (HGF). In a phase I clinical study, vemurafenib (then known as PLX4032) was ... Activates the ERK Pathway and Enhances Cell Migration and Proliferation of BRAF(WT) Melanoma Cells". Pigment Cell Melanoma Res ... Vemurafenib causes programmed cell death in melanoma cell lines. Vemurafenib interrupts the B-Raf/MEK step on the B-Raf/MEK/ERK ... Cancer cells begin to overexpress cell surface protein PDGFRB, creating an alternative survival pathway. A second oncogene ...
*  SDF4
J Cell Biol. 133 (2): 257-68. doi:10.1083/jcb.133.2.257. PMC 2120788 . PMID 8609160. "Entrez Gene: SDF4 stromal cell derived ... binding proteins localised to the secretory pathway of mammalian cells". FEBS Lett. 466 (1): 11-8. doi:10.1016/S0014-5793(99) ... Cell. 18 (7): 2473-80. doi:10.1091/mbc.E06-10-0950. PMC 1924827 . PMID 17442889. ...
*  Granulopoiesis
"Candida albicans can stimulate stromal cells resulting in enhanced granulopoiesis". Stem Cells Dev. 13 (1): 39-50. doi:10.1089/ ... Pluripotential hemopoietic stem cell Myeloblast Promyelocyte Eosino/neutro/basophilic myelocyte Metamyelocyte Band cell (Stab ... cell) Granulocytes (Eosino/neutro/basophil) It can be stimulated by Candida albicans. Basu S, Zhang HH, Quilici C, Dunn AR ( ...
*  Gonadal tissue neoplasm
These tissues arise from the sex cord and stromal cells. The tumor may be derived from these tissues, or produce them. Although ... A gonadal tissue neoplasm is a tumor having any histology characteristic of cells or tissues giving rise to the gonads. ...
*  Hemangioblastoma
... s are composed of endothelial cells, pericytes and stromal cells. In VHL syndrome the von Hippel-Lindau protein ... Hemangioblastomas are most commonly composed of stromal cells in small blood vessels and usually occur in the cerebellum, brain ... In these dysfunctional cells pVHL cannot degrade HIF-1α, causing it to accumulate. HIF-1α causes the production of vascular ... They may be associated with other diseases such as polycythemia (increased blood cell count), pancreatic cysts and Von Hippel- ...
*  BST1
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that ... a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth". Proc Natl Acad Sci U S A. 91 (12): ... "Entrez Gene: BST1 bone marrow stromal cell antigen 1". Human BST1 genome location and BST1 gene details page in the UCSC Genome ... 1996). "Elevated levels of the soluble form of bone marrow stromal cell antigen 1 in the sera of patients with severe ...
*  Corneal keratocyte
West-Mays JA, Dwivedi DJ (2006). "The keratocyte: corneal stromal cell with variable repair phenotypes". Int. J. Biochem. Cell ... "Interleukin-1alpha downregulates extracellular-superoxide dismutase in human corneal keratoconus stromal cells". Mol. Vis. 13: ... Cell Dev. Biol. 19 (2): 100-12. doi:10.1016/j.semcdb.2007.10.004. PMID 18077195. Lassen N, Pappa A, Black WJ, Jester JV, Day BJ ... Cell Dev. Biol. 19 (2): 82-93. doi:10.1016/j.semcdb.2007.09.015. PMC 2275913 . PMID 17997336. Lassen N, Black WJ, Estey T, ...
*  Sp7 transcription factor
Tu Q, Valverde P, Chen J (2006). "Osterix enhances proliferation and osteogenic potential of bone marrow stromal cells". ... In mesenchymal precursor cells expressing Runx-2, Sp7 expression will induce these cells to differentiate into osteoblasts, and ... "Telomerase accelerates osteogenesis of bone marrow stromal stem cells by upregulation of CBFA1, osterix, and osteocalcin". ... Kaback LA, Soung do Y, Naik A, Smith N, Schwarz EM, O'Keefe RJ, Drissi H (2008). "Osterix/Sp7 regulates mesenchymal stem cell ...
*  Plant matrix metalloproteinase
Its RNA was taken from stromal cells in human breast carcinomas. Based on the PUMP sequence and functionality of carcinomas in ... The most basic description of the plant extracellular matrix (ECM) is the cell wall, but it is actually the cell surface ... The ECM is composed of the primary and secondary cell walls, along with the intercellular gap between its neighboring cells. ... In the leaves, the MMP gene was expressed in the phloem, developing xylem elements, neighboring mesophyll cell layers, and ...
*  Deferoxamine
"Proliferation and differentiation of bone marrow stromal cells under hypoxic conditions". Biochemical and Biophysical Research ... It is also used to induce hypoxia-like environment in mesenchymal stem cells. Chelation therapy "Deferoxamine Mesylate". The ... Deferoxamine may modulate expression and release of inflammatory mediators by specific cell types. Deferoxamine is being ... "Iron chelator triggers inflammatory signals in human intestinal epithelial cells: Involvement of p38 and extracellular signal- ...
*  CRABP2
"Retinoic acid suppresses in-vitro decidualization of human endometrial stromal cells". Molecular Human Reproduction. 2 (3): 185 ... Structures such as the limbs, hindbrain and cranial neural crest cells have been shown to be excessively sensitive to high ... cells that produce large amounts of retinoic acid and may play a role in mediating the effects of retinoic acid in the cell. A ... Cytogenetics and Cell Genetics. 76 (1-2): 17-8. doi:10.1159/000134502. PMID 9154115. Brar AK, Kessler CA, Meyer AJ, Cedars MI, ...
*  25-Hydroxyvitamin D3 1-alpha-hydroxylase
Zhou S, LeBoff MS, Glowacki J (Jan 2010). "Vitamin D metabolism and action in human bone marrow stromal cells". Endocrinology. ... immune cells, and bone (osteoblasts). The enzyme catalyzes the hydroxylation of Calcifediol to calcitriol (the bioactive form ... T cell attraction to the epidermal chemokine CCL27" (PDF). Nature Immunology. 8 (3): 285-93. doi:10.1038/ni1433. PMID 17259988 ... "1alpha-hydroxylase and innate immune responses to 25-hydroxyvitamin D in colonic cell lines". The Journal of Steroid ...
*  UBL7
Ubiquitin-like 7 (bone marrow stromal cell-derived) is a protein in humans that is encoded by the UBL7 gene. GRCh38: Ensembl ...
*  CD34
It may also mediate the attachment of stem cells to bone marrow extracellular matrix or directly to stromal cells. The CD34 ... Cells expressing CD34 (CD34+ cell) are normally found in the umbilical cord and bone marrow as hematopoietic cells, or in ... in a cell surface glycoprotein and functions as a cell-cell adhesion factor. ... endothelial cells of blood vessels but not lymphatics (except pleural lymphatics), mast cells, a sub-population dendritic cells ...
*  Forkhead box d1
BF2 and stromal cell have essential function during kidney Morphogenesis. Placental growth factor (PIGF) is a direct and ... Delayed expression of FOX D1 causes decreased glioma cell growth and reduce cell migration. There is a high probability that ... FOX D1 is expressed by two kidney derived cell line COS 7 and 293 cells. It also has high degree of sequence similarity with ... First, PIGF initiates stromal signal that regulate epithelial differentiation which functions as a growth factor in reactive ...