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*  Spiro compound
... rings is called the spiro atom; in carbocyclic spiro compounds like spiro[5.5]undecane (see image at right), the spiro-atom is ... The atom connecting the two rings is called the spiro-atom; in carbocyclic spiro compounds, the spiro-atom is a quaternary ... is a spiro compound in its own right, and yields the further spiro carbinol and the alicyclic spiro hydrocarbon after two ... Nomenclature for spiro compounds was first discussed by Adolf von Baeyer in 1900. Spiro compounds are named with the infix ...
*  Thorpe-Ingold effect
The formation and stability of spiro-compounds. Part I. Spiro-Compounds from cyclohexane". J. Chem. Soc., Trans. 107: 1080. doi ... This compounds are active in the cleavage of the RNA model compound HPNP. Substitution of the methylene group of the parent ...
*  Prospidium chloride
Chemically, it is a spiro compound. Benenson, E. V.; Timina, O. B. (1994). "Prospidine versus methotrexate pulse in highly ...
*  Fenestrane
They can be regarded as spiro compounds twice over. Because of their inherent strain and instability, fenestranes are of ... compounds and their salts are more likely to form crystalline compounds suitable for X-ray analysis than low-molecular-weight ... A fenestrane in organic chemistry is a type of chemical compound with a central quaternary carbon atom which serves as a common ...
*  Alicyclic compound
Spiro compounds have two or more rings that are connected through only one carbon atom. The mode of ring-closing in the ... An alicyclic compound is an organic compound that is both aliphatic and cyclic. They contain one or more all-carbon rings which ... Alicyclic compounds may have one or more aliphatic side chains attached. The simplest alicyclic compounds are the monocyclic ... Isotoluenes are a prominent class of compounds with exocyclic double bonds. The placement of double bonds in many alicyclic ...
*  Geodia exigua
... is a species of sponges that produces the sesquiterpene spiro compound exiguamide. The species was first ...
*  Tetraethoxymethane
... whereby spiro compounds can also be obtained. Spiro orthocarbonates (SOCs) are of some industrial interest, as they are used as ... Tetraethoxymethane can be used as a solvent and for the alkylation of CH-acidic compounds (e.g. phenols and carboxylic acids). ... D.T. Vodak et al., One-Step Synthesis and Structure of an Oligo(spiro-orthocarbonate), J. Am. Chem., Soc., 124, 4942-4943 (2002 ... R. Acosta Ortiz et al., Novel diol spiro orthocarbonates derived from glycerol as anti-shrinkage additives for the cationic ...
*  Fluorescamine
... is a spiro compound that is not fluorescent itself, but reacts with primary amines to form highly fluorescent ...
*  Fenspiride
... (INN, brand names Eurespal, Pneumorel and others) is an oxazolidinone spiro compound used as a drug in the treatment ...
*  Ring (chemistry)
Cyclic compound Polycyclic compound Heterocyclic compound Bicyclic molecule Spiro compound IUPAC, Compendium of Chemical ... is termed a polycyclic compound. A molecule containing no rings is called an acyclic or open-chain compound. A homocycle or ... A molecule containing one or more rings is called a cyclic compound, and a molecule containing two or more rings (either in the ... the "Gold Book") (1997). Online corrected version: (1995) "Homocyclic compounds". IUPAC, Compendium of Chemical Terminology, ...
*  Polycyclic compound
... such as in spiro compounds), and bridged cyclics such as the longifolene example. Though poly- literally means "many", there is ... as well as heterocyclic aromatic compounds with multiple rings (where heteroaromatic compounds are aromatic compounds that ... In the field of organic chemistry, a polycyclic compound is an organic chemical featuring several closed rings of atoms, ... In general, the term polycyclic includes polycyclic aromatic compounds, including polycyclic aromatic hydrocarbons, ...
*  Spiropentane
... discovery in 1887 until the structure of the molecule was determined.According to the nomenclature rules for spiro compounds, ... The spiro hydrocarbon can be separated from the byproducts (2-methyl-1-butene, 1,1-dimethylcyclopropane, methylenecyclobutane) ... It is the simplest spiro-connected cycloalkane, a triangulane. It took several years after the ... the systematic name is spiro[2.2]pentane. However, there can be no constitutive isomeric spiropentanes, hence the name is ...
*  Bicyclic molecule
Fused and bridged bicyclic compounds get the prefix bicyclo, whereas spirocyclic compounds get the prefix spiro. In between the ... An example of a spirocyclic compound is the photochromic switch spiropyran. In fused bicyclic compounds, two rings share two ... When naming simple fused bicyclic compounds, the same method as for bridged bicyclic compounds is applied, except the third ... In spirocyclic compounds, the two rings share only one single atom, the spiro atom, which is usually a quaternary carbon. ...
*  Spirolactone
... are a group of steroids which are both spiro compounds and lactones and which feature these two structural properties combined ... is the unsubstituted parent or prototype compound of the spirolactones, and is one of a few of the simplest members of the ... compounds (e.g., SC-9420 for spironolactone). The spirolactones include the marketed drugs spironolactone (SC-9420; Aldactone ...
*  Descriptor (Chemistry)
See: Spiro compound The prefix "spiro" followed by a Von-Baeyer descriptor describes in the nomenclature of organic compounds ... More generally, iso is a compound which is isomeric to the n compound (a compound in which individual atoms or atomic groups ... "spiro" is provided with a prefix ("dispiro", "trispiro", etc.) corresponding to the number of spiro atoms. Typically "spiro" is ... for cyclo this is only the case in inorganic compounds. In organic compounds, "cyclo" is frequently used as a name component, ...
*  Spiropentadiene
... and followed by two successive reactions with chlorocarbene generated from methyllithium and dichloromethane to spiro compound ... The simplest spiro-connected cycloalkene, it is very unstable-decomposing even below −100 °C-due to its high bond strain and ... In contrast to the carbon parent this compound is stable with a melting point of 216 to 218 °C. The angle between the two rings ... doi:10.1016/S0040-4039(99)01293-9. Iwamoto, T.; Tamura, M.; Kabuto, C.; Kira, M. (2000). "A Stable Bicyclic Compound with Two ...
*  Bombyx mori
A novel spiro-heterocyclic compound identified by the silkworm infection model inhibits transcription in Staphylococcus aureus ... They also created implants made of silk and drug compounds which can be implanted under the skin for steady and gradual time ...
*  Bridged compounds
... and from spiro compounds that have two rings linked by a single atom. Bridged compounds may be fully carbocyclic (all carbon) ... A bridged compound is a chemical compound, generally an organic compound, but also possibly inorganic, that has two or more ... distinguishes bridged compounds from fused ring compounds that have two rings linked by two adjacent atoms, ... "Extension and Revision of the von Baeyer System for Naming Polycyclic Compounds (Including Bicyclic Compounds); (IUPAC ...
*  Debromoaplysiatoxin
This compound combines spiro acetal, hemiactal and diolide functionalities, which result in peculiar biological activities. To ... Therefore, this compound is of interest for study: by finding which groups cause the tumor-promoting activity, and removing ... The compound was first isolated from the digestive tract of the sea hare Stylocheilus longicauda. Accidental skin contact with ... This indicates that the compound isn't excreted by the animals causing a higher risk of death related to the amount of food ...
*  TNP-ATP
... as is characteristic of a Meiseinheimer spiro complex compound linking. To see the exact method of preparion, please refer to T ... TNP refers to the chemical compound 2,4,6-trinitrophenol, also known as Picric acid. It is a primary constituent of many ... Adenosine's ribose moiety can be trinitrophenylated by 2,4,6-trinitrobenzene-1-sulfonate (TNBS). The resulting compound assumes ...
*  Organic chemistry
Such compounds are termed spiro and are important in a number of natural products. One important property of carbon is that it ... Both saturated (alicyclic) compounds and unsaturated compounds exist as cyclic derivatives. The most stable rings contain five ... Converting individual petroleum compounds into different types of compounds by various chemical processes led to organic ... The depiction of organic compounds with drawings is greatly simplified by the fact that carbon in almost all organic compounds ...
*  Excited state
... and TDDFT Studies of Charge Transfer Processes in Mixed-Valence Compounds: Application to the Spiro Molecule". The Journal of ...
*  Expanding Monomers
Compound classes which are fulfilling these requirements are spiro orthoesters, spiro orthocarbonates, bicyclic ketal lactones ... The epoxide cyclohexene oxide and the lactone γ-butyrolactone are reacting to the spiro orthoester spiro-7-9-dioxacyclo[4.3.0] ... The polymerization of a cyclic compound causes therefore a smaller volume shrinkage because cyclic compounds are already ... Spiro orthoesters are forming, when homopolymerized, polyether polyesters. The reaction mechanism is not yet clear in details, ...
*  Discovery and development of tubulin inhibitors
Preparation of 10-α-spiro epoxide and its 7-MOM ether gave compounds having comparable cytotoxicity and tubulin assembly ... These compounds inhibit cell mitosis by binding to the protein tubulin in the mitotic spindle and preventing polymerization or ... The first known compound which binds to tubulin was colchicine, it was isolated from the autumn crocus, Colchicum autumnale, ... Discover new compounds active against drug-resistant cancers with different mechanism than drugs have been already known. ...
*  Metal-organic framework
... or spiro-links, or a coordination compound extending through repeating coordination entities in two or three dimensions; and ... These compounds employ amino acids(L- or D-aspartate) together with dipyridyls as struts. The coordination chemistry is such ... While the nickel-based compounds are marginally porous, on account of tiny channel dimensions, the copper versions are clearly ... Metal-organic frameworks (MOFs) are compounds consisting of metal ions or clusters coordinated to organic ligands to form one ...
*  Sigma-1 receptor
... spiro[1H-isobenzofuran-3,4'-piperidine] 1'-benzyl-6-methoxy-1-phenyl-spiro[6H-furo[3,4-c]pyrazole-4,4'-piperidine] (−)-(S)-4- ... Much is known about the binding affinity of hundreds of synthetic compounds to the σ1 receptor. An endogenous ligand for the σ1 ... 1. N-substituted spiro[piperidine-4,4'-thieno[3,2-c]pyrans]". Journal of Medicinal Chemistry. 51 (20): 6531-7. doi:10.1021/ ... assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and ...