Traumatic brain injury Spinal cord injury Alzheimer's disease Aging Stroke Epilepsy Alcoholism Drug abuse Fluoro-jade may also ... Duckworth, E.A.M.; Butler, T.; Collier, L.; Collier, S.; Pennypacker, K. R. (2006). "NF-kappaB protects neurons from ischemia ... "Fluoro-Jade B stains quiescent and reactive astrocytes in the rodent spinal cord". J. Neurotrauma. 20 (11): 1223-1231. doi: ... "Fluoro-jade stains quiescent and reactive astrocytes in the rodent spinal cord". J. Neurotrauma. 20 (11): 1223-1231. doi: ...
Joseph Yanai) Kang KS, Kim SW, Oh YH, Yu JW, Kim KY, Park HK, Song CH, Han H (2005). "A 37-year-old spinal cord-injured female ... Critical Limb Ischemia Research is underway to develop various sources for stem cells, and to apply stem cell treatments for ... 21 (1 Spinal Cord Disorders): 201-205. doi:10.1212/01.CON.0000461094.76563.be. PMID 25651226. Du, Li; Rachul, Christen; Guo, ... However, the human trial was not initiated until October 13, 2010 in Atlanta for spinal cord injury research. On November 14, ...
Acute trauma to the brain or spinal cord results in gliosis, most often in its severe form with the development of a glial scar ... ischemia, and stroke. Additionally, gliosis is present in a wide variety of CNS pathologies, including Alzheimer's disease, ...
... and in spinal cord injury. He has also been a film actor and is currently a member of the Board of Trustees of the Doris Duke ... states: "The concept of generation of free radicals during ischemia was first presented by Demopoulos, Flamm and co-workers ... "Oxidative damage following cerebral ischemia depends on reperfusion - a biochemical study in rat". Journal of Cellular and ...
... and his anatomical studies of the brain and spinal cord. He regarded English anatomist Thomas Willis (1621-1675) as a major ... This collateral blood supply reduces ischemia and protects that part of myocardium from complete necrosis. Among his written ...
Shay, J.; Gonatas, N. K. (1973). "Electron microscopy of cat spinal cord subject to circulatory arrest and deep local ... Shay, J.; Ames, III (1976). "Retina Subjected to Components of Ischemia In Vitro: Selective Vulnerability and Minimum Lethal ... "Morphometry of an ischemic lesion of cat spinal cord". The American Journal of Pathology. 72 (3): 397-402. PMC 1904035. PMID ...
... a 3mm deep furrow on the anterior side of the spinal cord, to the anterior horn of the spinal cord, the ventral grey matter of ... causing local ischemia and vessel damage which result in tumor spillage into the Virchow-Robin spaces and providing access to ... Infiltration of the spinal cord parenchyma is found with destruction of the pia mater. Tumor cell infiltration is associated ... More regarding the effects of NM on spinal cord is discussed later. Tumor cells may also seed the choroid plexus, where CSF is ...
Neurostimulation, from a device such as a spinal cord stimulator (SCS), for refractory angina has been shown to be effective in ... Myocardial ischemia, the most frequent cause of cardiac pain, is the most common cause of death in the United States. Urinary ... nerve fibers entering the spinal cord at the same level as the superficial, somatic structures experiencing the pain. This ... "Symptomatic relief precedes improvement of myocardial blood flow in patients under spinal cord stimulation". Curr Control ...
In vitro spinal cord cultures with glutamate transport inhibitors led to degeneration of motor neurons, which was counteracted ... During ischemia, the brain has been observed to have an unnaturally high concentration of extracellular glutamate. This is ... Since spinal NMDA receptors link the area of pain to the brain's pain processing center, the thalamus, these glutamate ... In the case of traumatic brain injury or cerebral ischemia (e.g., cerebral infarction or hemorrhage), acute neurodegeneration ...
... spinal cord disorders, glomerulonephritis, head trauma, neoplasias, preeclampsia and eclampsia, hyperthyroidism and ... During a hypertensive crisis, this can lead to acute kidney ischemia, with hypoperfusion, involvement of other organs, and ... Hypertensives also have an increased cerebrovascular resistance which puts them at greater risk of developing cerebral ischemia ... Excessive reduction in blood pressure can precipitate coronary, cerebral, or kidney ischemia and, possibly, infarction.[ ...
13: Disordered Cardiovascular Control After Spinal Cord Injury". In Verhaagen, Joost; McDonald, John W. (eds.). Spinal Cord ... intestinal ischemia, or infected medical devices. Anaphylactic shock is treated with epinephrine. The use of vasopressin ... tone normally supported by the sympathetic nervous system due to injury to the central nervous system especially spinal cord ...
This is usually found after a rapid, locally triggered inflammatory response to acute traumatic injury in the spinal cord and ... Insults to neurons in the central nervous system caused by infection, trauma, ischemia, stroke, recurring seizures, autoimmune ... ischemia, stroke, autoimmune responses or neurodegenerative disease. In healthy neural tissue, astrocytes play critical roles ...
... including repair of the spinal cord, muscles, and other critically important tissues) has not yet been achieved. Early versions ... Unconsciousness occurs within 10 seconds without circulating oxygenated blood (brain ischemia). Cell death and irreversible ...
Intrauterine hypoxia can cause cellular damage that occurs within the central nervous system (the brain and spinal cord). This ... Ischemia is a restriction in blood supply to any tissue, muscle group, or organ, causing a shortage of oxygen. Ischemia is ... Common disorders that can cause respiratory disfunction include trauma to the head and spinal cord, nontraumatic acute ... focal cerebral ischemia, cerebral infarction, and global cerebral ischemia. Prolonged hypoxia induces neuronal cell death via ...
... spinal cord injury, traumatic brain injury, and stroke. A total of 113 injections were performed on the 31 patients, with one ... Cerebral ischemia/reperfusion (I/R) injury is the main pathophysiological process present in ischemic stroke. Apelin regulates ... This is due to the noradrenergic pain inhibitory system that is employed by these drugs, coupled with spinal receptors that ... Examples include the treatment of Spinal Muscular Atrophy (SMA), the administration of chemotherapy in gliomas, and the ...
"Tonic inhibitory role of α4β2 subtype of nicotinic acetylcholine receptors on nociceptive transmission in the spinal cord in ... Xenon is cardioprotective in ischemia-reperfusion conditions by inducing pharmacologic non-ischemic preconditioning. Xenon is ... Thus, the low frequencies of the sound wave produced by the same direct vibration of the vocal cords would be enhanced, ... Hence, xenon vibrates more slowly in the vocal cords when exhaled and produces lowered voice tones (low-frequency-enhanced ...
Psychological and behavioral issues in the treatment of pain after spinal cord injury. Topics in Spinal Cord Injury, 7, 73-83. ... 2007) An interactive model of pain and myocardial ischemia. Psychosomatic Medicine, 69(7), 632-9. PMID 17766689 Boyd C, Boult C ... PMID 1633388 Elliott, T.R. & Wegener, S.T. (Eds.). (1992). Chronic pain and spinal cord injury (Special section). The Clinical ... San Jose Mercury News Bor, Jonathan (July 30, 2000). Baltimore's street violence creates an epidemic of spinal cord injuries. ...
TRAAK is only expressed in neuronal tissue, and can be found in the brain, spinal cord, and retina, which suggests that it has ... High TRAAK channel density has also been implicated in the resulting cerebral ischemia following the event of a stroke. Tandem ... "Deletion of TRAAK potassium channel affects brain metabolism and protects against ischemia". PLOS ONE. 7 (12): e53266. Bibcode: ...
The visceral sensory information from the gut traveling to the spinal cord, termed the visceral afferent, is non-specific and ... Locations and associated conditions include: Diffuse Peritonitis Vascular: mesenteric ischemia, ischemic colitis, Henoch- ... Therefore, visceral afferent information traveling to the spinal cord can present in the distribution of the somatic afferent ... of the gut has an associated visceral afferent nerve that transmits sensory information from the viscera to the spinal cord, ...
... microdiscectomy and placement of a spinal cord stimulator. The MILD procedure aims to relieve spinal cord compression by ... compression and/or ischemia of a single or multiple nerve roots within an intervertebral foramen or the central spinal canal. ... to enter the spinal cord and release pressure on the nerve roots. Laminoplasty and spinal fusion surgeries are other ... Yang YM, Yoo WK, Bashir S, Oh JK, Kwak YH, Kim SW (2018). "Spinal Cord Changes After Laminoplasty in Cervical Compressive ...
... spinal cord injury, those with injury above thoracic vertebrae 5 (T5) will have hypomotility problems within the bowel acute ... because intestinal segments have more prolonged contact and intestinal distention causes serosal injury and ischemia. It is ...
ISBN 978-0-07-180092-1. Lee BY, Guerra J (1994). "Axillofemoral bypass graft in a spinal cord injured patient with impending ... and critical limb ischemia.[citation needed] The physical examination usually shows weakened femoral pulses and a reduced ankle ...
... spinal column irregularities may tweak the spinal cord briefly when the head or back is turned, flexed, or extended into brief ... Reactive hyperaemia, which occurs when blood flow is restored after a period of ischemia, may be accompanied by paresthesia, e. ... pesticides Post Polio Syndrome Rabies Radiation poisoning Sarcoidosis Scorpion stings Spinal disc herniation or injury Spinal ...
Multiple sclerosis Spinal cord lesions Mechanical outlet obstruction Internal intussusception Enterocele Dissipation of force ... The prognosis for non-ischemic cases of SBO is good with mortality rates of 3-5%, while prognosis for SBO with ischemia is fair ... Complications may include sepsis, bowel ischemia and bowel perforation. About 3.2 million cases of bowel obstruction occurred ... bowel ischemia or perforation from prolonged distension or pressure from a foreign body and subsequently sepsis due to bowel ...
In the central nervous system ASIC's are usually found in the dorsal horn of the spinal cord. ASIC1 is specifically ... suggesting ASIC channels play a major role in the development of the pathological states resulting from acidosis and ischemia ...
... receptors in the mouse spinal cord". Life Sciences. 68 (6): 719-25. doi:10.1016/s0024-3205(00)00975-9. PMID 11205886. Nagase H ... intracerebroventricular injection of delta-opioid receptor agonist TAN-67 or antagonist naltrindole on acute cerebral ischemia ... appearance of irreversible damages of cardiomyocytes and exacerbates myocardial contractility dysfunction during ischemia and ...
... spinal cords, arteries and other tissues. Following this, Panitch was named one of four University Faculty Scholars from the ... she was the recipient of a 2019 Science Translation and Innovative Research Grant to help fund her research with ischemia- ...
... involvement of Sulfatase 1 in modulating Shh signaling in the ventral spinal cord". The Journal of Neuroscience. 26 (19): 5037- ... Investigators found that HSPGs such as perlecan and collagen type XVIII are modified during human renal ischemia/reperfusion, ... heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/ ...
American actor, director, producer, and writer Christopher Reeve had the acute form of SMA syndrome as a result of spinal cord ... from prolonged mesenteric ischemia), gastric distention, spontaneous upper gastrointestinal bleeding, hypovolemic shock, and ... Spinal Cord. 40 (2): 88-91. doi:10.1038/sj.sc.3101255. PMID 11926421. Barsoum MK, Shepherd RF, Welch TJ (August 2008). "Patient ... Errico, Thomas J. "Surgical Management of Spinal Deformities", 458 Buresh CT, Graber MA (2006). "Unusual Causes of Recurrent ...
Paraesthesias or weakness involving a dermatome indicate probable spinal cord or spinal nerve root involvement. Although it is ... Deep, non-localised pain not affected by movement suggests bone medulla involvement, with ischaemia due to blood vessel ... Distribution of spinal cord lesions may be related to vascular supply. There is still uncertainty regarding the aetiology of ... Necrosis has frequently been reported in the lower cervical, thoracic, and upper lumbar regions of the spinal cord. A ...