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*  Ovarian follicle
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries. It secretes hormones that influence ...
*  3D bioprinting
In some processes, the cells are encapsulated in cellular spheroids 500μm in diameter. This aggregation of cells does not ... There is a "scaffold-free" model that uses self-assembling spheroids that subjects to fusion and cell arrangement to resemble ... The application of biomimicry in bioprinting involves creating both identical cellular and extracellular parts of organs. For ...
*  Titanocene Y
Weber H, Claffey J, Hogan M, Pampillón C, Tacke M (2008). "Analyses of Titanocenes in the spheroid-based cellular angiogenesis ...
*  Glucose-6-phosphate isomerase
"GPI/AMF inhibition blocks the development of the metastatic phenotype of mature multi-cellular tumor spheroids". Biochimica et ... One study showed that the external layers of breast tumor spheroids (BTS) secrete GPI, which induces epithelial-mesenchymal ...
*  3D cell culture
3D spheroids more closely resemble in vivo tissue in terms of cellular communication and the development of extracellular ... spheroids are 3-6 times softer than MCF 10A (normal epithelial) spheroids. Spheroids co-cultured with tumor and healthy cells ... Spheroids can be grown with a few different methods. One common method is to use low cell adhesion plates, typically a 96 well ... 3D spheroids have been cultured in a lab setting for up to 302 days while still maintaining healthy, non-cancerous growth. ...
*  3D cell culturing by magnetic levitation
Shown in the picture above is an invasion assay of magnetically levitated multicellular spheroids. Fluorescence images of human ... such as for increasing the accuracy of cellular assays as shown in the figure below. ...
*  Tissue engineering
They are easy to open and close, so that cell spheroids can be removed for testing, yet the chamber is able to maintain 100% ... In this methodology, all material in the construct is cellular or material produced directly by the cells themselves. Doris ... Scaffolds are materials that have been engineered to cause desirable cellular interactions to contribute to the formation of ... Friedrich J, Seidel C, Ebner R, Kunz-Schughart LA (2009). "Spheroid-based drug screen: considerations and practical approach". ...
*  Evolution of cells
... and multi-cellular organisms could be achieved.[citation needed] The common ancestor of the now existing cellular lineages ( ... Partitioning may have begun from cell-like spheroids formed by proteinoids, which are observed by heating amino acids with ... Scientific interest in cellular evolution started to pick up once the universal phylogenetic tree, the framework within which ... It is postulated that this symbiotic partnership progressed via the cellular fusion of the partners to generate a chimeric or ...
*  Lentoid
Disc Oblate sphere Spheroid Timeline of Art History: Lentoid seal with a griffin, Minoan Crete C. Michael Hogan, Knossos ... The term is most often used in describing jewelry and cellular phenomena in microbiology. Since ancient times, the lentoid ...
*  Water tower
A water spheroid looks like a water sphere, but the top is wider than it is tall. A spheroid looks like a round pillow that is ... or cellular telephone service. In hilly regions, local topography can be substituted for structures to elevate the tanks. These ... Both spheres and spheroids are special-case ellipsoids: spheres have symmetry in 3 directions, spheroids have symmetry in 2 ... A cross section of a spheroid in two directions (east-west or north-south) is an ellipse, but in only one direction (top-bottom ...
*  Archean life in the Barberton Greenstone Belt
Because the Earth is 4.5 billion years old, there is a window of about one billion years for cellular life to evolve from a ... Though there is no established range of sizes for each type, spheroid microfossils can be as small as about 8 μm, filamentous ... There is also ongoing work within the scientific community to solve the problem of how cellular life evolved in a hostile early ... It is important to note that cellular life existed 3.5 billion years ago and thus it evolved prior to this time. ...
*  Embryoid body
Tung, Y. C.; Hsiao, A. Y.; Allen, S. G.; Torisawa, Y. S.; Ho, M.; Takayama, S. (2011). "High-throughput 3D spheroid culture and ... "Magnetic manipulation and spatial patterning of multi-cellular stem cell aggregates". Integrative Biology. 3 (12): 1224-1232. ... In contrast to monolayer cultures, however, the spheroid structures that are formed when ESCs aggregate enables the non- ... Chang, T. T.; Hughes-Fulford, M. (2009). "Monolayer and Spheroid Culture of Human Liver Hepatocellular Carcinoma Cell Line ...
*  Robotic sperm
The sperm cell is the actuation source for the magnetic microstructure and can propel it to cancer spheroids. At this location ... "Cellular Cargo Delivery: Toward Assisted Fertilization by Sperm-Carrying Micromotors". Nano Letters. 16: 555-561. Bibcode: ...
*  Rhodobacter sphaeroides
Also, when exposed to a reduction in the partial pressure of oxygen, R. sphaeroides develops invaginations in its cellular ... Twenty sRNAs were experimentally identified in Rhodobacter spheroids, and the abundant ones were shown to be affected by ...
*  Organoid
... s provide an opportunity to create cellular models of human disease, which can be studied in the laboratory to better ... "Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids". Nature ... Cellular and Developmental Biology. 38 (2): 181-191. doi:10.1002/bies.201500111. ISSN 1521-1878. PMC 4737349 . PMID 26666846. ... a protocol for culturing cerebral organoids derived from stem cells that mimic the developing human brain's cellular ...
*  Cell-based models
On-lattice models such as cellular automata or cellular potts restrict the spatial arrangement of the cells to a fixed grid. ... Drasdo, Dirk; Höhme, Stefan (2005). "A single-cell-based model of tumor growth in vitro : monolayers and spheroids". Physical ... The mechanical interactions are then carried out according to literature-based rules (cellular automata) or by minimizing the ... "A review of spatial computational models for multi-cellular systems, with regard to intestinal crypts and colorectal cancer ...
*  ROR1
... form spheroids, or engraft immune-deficient mice. Moreover, such treatment inhibited the growth of tumor xenografts, which in ... Molecular and Cellular Biology. 21 (24): 8329-35. doi:10.1128/MCB.21.24.8329-8335.2001. PMC 99997 . PMID 11713269. Baskar S, ... on which it seems to play a functional role in promoting migration/invasion or spheroid formation in vitro and tumor ...
*  CRISPR
These CRISPR-generated cellular models, with isogenic controls, provide a new way to study human disease and test drugs. Gene ... "Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids". Nature ... CRISPR can be utilized to create human cellular models of disease. For instance, applied to human pluripotent stem cells CRISPR ... "Directing cellular information flow via CRISPR signal conductors". Nature Methods. 13 (11): 938-944. doi:10.1038/nmeth.3994. ...
*  Knee cartilage replacement therapy
The cells grow in self-organized spheroid matrices which are implanted via injected fluid or inserted tissue matrix. For years ... Some additional examples of cartilage failure mechanisms include cellular matrix linkage rupture, chondrocyte protein synthesis ...
*  MYOT
Spheroid Body Myopathy and Distal Myopath. The mechanism underlying the pathology is still under investigation. It has been ... Molecular and Cellular Biology. 29 (3): 822-34. doi:10.1128/MCB.01454-08. PMC 2630697 . PMID 19047374. Moza M, et al. (2007). " ... "A mutation in myotilin causes spheroid body myopathy". Neurology. 65 (12): 1936-40. doi:10.1212/01.wnl.0000188872.28149.9a. ...
*  Dielectrophoresis
... in cellular terms, the cytoplasm), 2 is the shell (in a cell, the membrane). r1 is the radius from the centre of the sphere to ... as oblate spheroids) or long thin tubes (as prolate ellipsoids) allowing the approximation of the dielectrophoretic response of ...
*  Cytochrome P450, family 1, member A1
"AHR/CYP1A1 interplay triggers lymphatic barrier breaching in breast cancer spheroids by inducing 12(S)-HETE synthesis". Hum Mol ... Molecular and Cellular Biology portal. ...
*  Nucleosome
The maintenance of a repressed or activated status of a gene is often necessary for cellular differentiation. Although histones ... ISBN 0-8153-4072-9. Olins AL, Olins DE (January 1974). "Spheroid chromatin units (v bodies)". Science. 183 (4122): 330-2. doi: ...
*  Cell culture
... is also a key technique for cellular agriculture, which aims to provide both new products and new ways of ... "384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids". Biotechnology and ... There are a variety of platforms used to facilitate the growth of three-dimensional cellular structures including scaffold ... Cell-to-cell contact can stimulate cellular differentiation. Genetic and epigenetic alterations, with a natural selection of ...
*  Neurodegeneration
Axonal swelling and spheroids have been observed in many different neurodegenerative diseases. This suggests that defective ... provide in vitro evidence that the primary cellular sites where SOD1 mutations act are located on astrocytes. Astrocytes then ... As research progresses, many similarities appear that relate these diseases to one another on a sub-cellular level. Discovering ... and abnormal interactions with other cellular proteins. PolyQ studies often use a variety of animal models because there is ...
*  List of OMIM disorder codes
PIK3CA Combined cellular and humoral immune defects with granulomas; 233650; RAG1 Combined cellular and humoral immune defects ... spheroid body; 182920; TTID Myopathy, X-linked, with postural muscle atrophy; 300696; FHL1 Myosclerosis, congenital; 255600; ...