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*  Hypothalamic-pituitary-somatotropic axis
... somatostatin), and ghrelin (GHS) are involved in the control of GH secretion from the pituitary gland. The HPS axis is involved ...
*  Somatostatin
In addition, somatostatin release from delta cells can act in a paracrine manner. In the stomach, somatostatin acts directly on ... "Entrez Gene: Somatostatin". Shen LP, Pictet RL, Rutter WJ (August 1982). "Human somatostatin I: sequence of the cDNA". ... Somatostatin inhibits insulin and glucagon secretion. Somatostatin has two active forms produced by alternative cleavage of a ... Humans have only one somatostatin gene, SST. Synonyms of somatostatin are as follows: growth hormone-inhibiting hormone (GHIH) ...
*  Somatostatin receptor
There are five known somatostatin receptors: SST1 (SSTR1) SST2 (SSTR2) SST3 (SSTR3) SST4 (SSTR4) SST5 (SSTR5) All are G protein ... Somatostatin Receptor at the US National Library of Medicine Medical Subject Headings (MeSH). ... "Classification and nomenclature of somatostatin receptors". Trends Pharmacol. Sci. 16 (3): 86-8. doi:10.1016/S0165-6147(00) ...
*  Somatostatin family
The Somatostatin family is a protein family with somatostatin as titular member, a hormone which inhibits the release of the ...
*  Somatostatin receptor 3
Shekel Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene. Somatostatin acts at many sites ... "Entrez Gene: SSTR3 somatostatin receptor 3". Yamada Y, Reisine T, Law SF, Ihara Y, Kubota A, Kagimoto S, Seino M, Seino Y, Bell ... somatostatin receptor 3 at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ... Corness JD, Demchyshyn LL, Seeman P, Van Tol HH, Srikant CB, Kent G, Patel YC, Niznik HB (April 1993). "A human somatostatin ...
*  Somatostatin receptor 1
Somatostatin receptor type 1 is a protein that in humans is encoded by the SSTR1 gene. Somatostatin acts at many sites to ... "In vitro characterization of somatostatin receptors in the human thymus and effects of somatostatin and octreotide on cultured ... "Entrez Gene: SSTR1 somatostatin receptor 1". Yamada Y, Post SR, Wang K, Tager HS, Bell GI, Seino S (January 1992). "Cloning and ... somatostatin receptor type 1 at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates ...
*  Somatostatin receptor 5
Somatostatin receptor type 5 is a protein that in humans is encoded by the SSTR5 gene. Somatostatin acts at many sites to ... 2001). "Mutation of somatostatin receptor type 5 in an acromegalic patient resistant to somatostatin analog treatment". J. Clin ... somatostatin receptor type 5) with preferential affinity for somatostatin-28". Mol. Pharmacol. 45 (3): 417-27. PMID 7908405. ... "Entrez Gene: SSTR5 somatostatin receptor 5". Yamada Y, Post SR, Wang K, et al. (1992). "Cloning and functional characterization ...
*  Somatostatin receptor 4
Somatostatin receptor type 4 is a protein that in humans is encoded by the SSTR4 gene. Somatostatin acts at many sites to ... "Entrez Gene: SSTR4 somatostatin receptor 4". Patel YC (July 1999). "Somatostatin and its receptor family". Frontiers in ... "Cloning and expression of a human somatostatin-14-selective receptor variant (somatostatin receptor 4) located on chromosome 20 ... Yamada Y, Stoffel M, Espinosa R, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (February 1993). "Human somatostatin receptor ...
*  Somatostatin receptor 2
Somatostatin receptor type 2 is a protein that in humans is encoded by the SSTR2 gene. Somatostatin acts at many sites to ... "Entrez Gene: SSTR2 somatostatin receptor 2". Zitzer H, Hönck HH, Bächner D, Richter D, Kreienkamp HJ (Nov 1999). "Somatostatin ... Somatostatin receptor 2 has been shown to interact with SHANK2. Most pituitary adenomas express SSTR2, but other somatostatin ... somatostatin receptor 2 at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ...
*  Functional Ensemble of Temperament
Somatostatin; PRL: prolactin; OXY: oxytocin; SubP: Substance P; NPY: Neuropeptide Y; KOPr, MOPr, DOPr: kappa-, mu- and delta- ...
*  Octreotide scan
It is also called somatostatin receptor scintigraphy (SRS). Octreotide, a drug similar to somatostatin, is radiolabeled with ... The radioactive octreotide attaches to tumor cells that have receptors for somatostatin. A gamma camera detects the radioactive ... Retrieved Mars 2011 Kwekkeboom, DJ; Krenning, EP (April 2002). "Somatostatin receptor imaging". Seminars in nuclear medicine. ... Somatostatin Receptor Imaging with 111In-Pentetreotide" (PDF). Neuroendocrinology. 90 (2): 184-189. doi:10.1159/000225946. PMID ...
*  Krenning score
The Krenning score is used to grade the uptake intensity of neuroendocrine tumors on somatostatin receptor imaging such as ... "Somatostatin receptor imaging". Seminars in nuclear medicine. 32 (2): 84-91. doi:10.1053/snuc.2002.31022. PMID 11965603. ...
*  Delirium
Broadly, delirium may be associated with: increased serotoninergic and dopamine signalling; reversible fall in somatostatin; ...
*  List of OMIM disorder codes
SHH Somatostatin analog, resistance to; 102200; SSTR5 Sorsby fundus dystrophy; 136900; TIMP3 Sotos syndrome; 117550; NSD1 ...
*  Glossary of diabetes
Somatostatin A hormone made by the delta cells of the pancreas (in areas called the islets of Langerhans). Scientists think it ... Delta cells make somatostatin, a hormone that is believed to control how the beta cells make and release insulin and how the ... which make somatostatin; F cells which make pancreatic polypeptide, and D1 cells, about which little is known. The names of the ...
*  Growth hormone
Other drugs like octreotide (somatostatin agonist) and bromocriptine (dopamine agonist) can be used to block GH secretion ... hypoglycemia, arginine and propranolol by inhibiting somatostatin release deep sleep niacin as nicotinic acid (Vitamin B3) ... Guillemin R, Gerich JE (1976). "Somatostatin: physiological and clinical significance". Annu. Rev. Med. 27: 379-88. doi:10.1146 ... GHIH or somatostatin) into the hypophyseal portal venous blood surrounding the pituitary. GH release in the pituitary is ...
*  Nardilysin
Gomez, S.; Gluschankof, P.; Morel, A.; Cohen, P. (1985). "The somatostatin-28 convertase of rat brain cortex is associated with ... A novel endoprotease that cleaves before the arginine-lysine doublet is involved in somatostatin-28 convertase activity of rat ... Gluschankof, P.; Gomez, S.; Morel, A.; Cohen, P. (1987). "Enzymes that process somatostatin precursors. ...
*  Arcuate nucleus
Centrally projecting neurons that make somatostatin; the neurosecretory somatostatin neurons that regulate growth hormone ... GHRH neurons help to control growth hormone (GH) secretion in conjunction with somatostatin and NPY. NPY/AgRP neurons and POMC/ ... 375-401 Kawano H, Daikoku S (1988). "Somatostatin-containing neuron systems in the rat hypothalamus: retrograde tracing and ... and somatostatin. Proopiomelanocortin (POMC) is a precursor polypeptide that is cleaved into MSH and β-endorphin and expressed ...
*  Octreotide
Since octreotide resembles somatostatin in physiological activities, it can: inhibit secretion of many hormones, such as ... Uhl W, Anghelacopoulos SE, Friess H, Büchler MW (1999). "The role of octreotide and somatostatin in acute and chronic ... Octreotide (trade name Sandostatin, among others) is an octapeptide that mimics natural somatostatin pharmacologically, though ... Octreotate, a closely related peptide Gøtzsche PC, Hróbjartsson A (2008). "Somatostatin analogues for acute bleeding ...
*  Vapreotide
... (Sanvar) is a synthetic somatostatin analog. It is used in the treatment of esophageal variceal bleeding in patients ...
*  Gastrointestinal bleeding
Somatostatin and octreotide, while recommended for varicial bleeding, have not been found to be of general use for non variceal ... "Somatostatin analogues for acute bleeding oesophageal varices". Cochrane Database of Systematic Reviews (3): CD000193. doi: ...
*  Regulation of gastric function
Low intragastric pH stimulates antral D cells to release somatostatin. Somatostatin inhibits gastrin release from G cells. ... 4.)In both the antrum and corpus, the vagus nerve inhibits D cells, thus reducing their release of somatostatin and reducing ...
*  Pylorus
These endocrine cells including D cells, which release somatostatin. (Somatostatin is responsible for shutting off acid ...
*  SNED1
... somatostatin (SST), somatostatin receptor 2 (SSTR2)as well as a variety of other somatostatin receptors, spermine synthase (SMS ... All of the somatostatin related proteins are involved in the inhibition of hormones. There is very little known about TMEM132C ... This protein is predicted to interact with somatostatin, spermidine synthase and TMEM132C. SNED1 is located on the plus strand ... somatostatin receptor ligands". Journal of Molecular Neuroscience. 18 (1-2): 15-27. doi:10.1385/JMN:18:1-2:15. PMID 11931345. ...
*  Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
Some patients have been treated with somatostatin analogs. Although the cough associated with DIPNECH tends to diminish on this ...