Somatic cell
Mitotic cell division is only seen in diploid somatic cells. Only some cells like germ cells take part in reproduction. As ... Like all cells, somatic cells contain DNA arranged in chromosomes. If a somatic cell contains chromosomes arranged in pairs, it ... "somatic cell nuclear transfer" and involves removing the nucleus from a somatic cell, usually a skin cell. This nucleus ... There are approximately 220 types of somatic cell in the human body. Theoretically, these cells are not germ cells (the source ...
Somatic cell count
A somatic cell count (SCC) is a cell count of somatic cells in a fluid specimen, usually milk. In dairying, the SCC is an ... White blood cells (leukocytes) constitute the majority of somatic cells in question. The number of somatic cells increases in ... the somatic cell count shall be not more than 400,000 cells per milliliter. The somatic cell count limit is 750,000 in the ... and are based on the somatic cell count and the bacteria plate count. Generally a lower somatic cell count indicates better ...
Somatic cell nuclear transfer
The second being a somatic cell, referring to the cells of the human body. Skin cells, fat cells, and liver cells are only a ... the somatic cell nucleus is reprogrammed by its host egg cell. The ovum, now containing the somatic cell's nucleus, is ... What is left is a somatic cell and an enucleated egg cell. These are then fused by inserting the somatic cell into the 'empty' ... "Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer". Cell. 153 (6): 1228-38. doi:10.1016/j.cell.2013.05.006. ...
Somatic Cell and Molecular Genetics
"Somatic Cell & Molecular Genetics". Retrieved 24 April 2011. "Somatic cell and molecular genetics. - NLM Catalog result". ... Somatic Cell Genetics. 1 (1): 1-2. doi:10.1007/BF01538728. Davidson, Richard L. (November 1983). "Editorial". Somatic Cell ... Somatic Cell and Molecular Genetics was a peer-reviewed scientific journal in the fields of cell biology and molecular genetics ... Somatic Cell and Molecular Genetics is fully indexed in Index Medicus, MEDLINE, and PubMed. Davidson, Richard L. (January 1975 ...
Somatic embryogenesis
... is an artificial process in which a plant or embryo is derived from a single somatic cell. Somatic ... Why somatic plant cells start to form embryos? In: Mujid, Abdul and Samaj, Josef. eds. Somatic Embryogenesis. Plant Cell ... Embryo production through somatic embryogenesis can be used to study cell differentiation in plants. Plant Cell Tiss. Org. Cult ... Description of somatic-embryo- forming single cells in carrot suspension cultures employing video cell tracking. Planta 194: ...
Somatic mutation and recombination tests
"Genotoxicity of two arsenic compounds in germ cells and somatic cells ofDrosophila melanogaster". Environmental and Molecular ... Carmona, Erico R.; Creus, Amadeu; Marcos, R. (January 2011). "Genotoxic effects of two nickel-compounds in somatic cells of ... It's worth noting that measuring mitotic recombination in somatic cells is important for genotoxicity screening since abnormal ... as well as nondisjunction and homologous mitotic recombination in w/w+ somatic cells of Drosophila in vivo These tests are ...
Somatic fusion
Somatic cells of different types can be fused to obtain hybrid cells. Hybrid cells are useful in a variety of ways, e.g., (i) ... Chromosome mapping through somatic cell hybridization is essentially based on fusion of human and mouse somatic cells. ... the cell wall of one cell of each type of plant using cellulase enzyme to produce a somatic cell called a protoplast The cells ... Subsequently, the two nuclei also fuse to yield a hybrid cell with a single nucleus. A generalized scheme for somatic cell ...
Uridine monophosphate synthase
Somatic Cell Genetics. 9 (3): 359-74. doi:10.1007/BF01539144. PMID 6574608. S2CID 29498380. McClard RW, Black MJ, Livingstone ... Somatic Cell and Molecular Genetics. 21 (3): 161-75. doi:10.1007/bf02254768. PMID 7482031. S2CID 21932938. Kanchanaphum P, ... Cell. 122 (6): 957-68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923. ... Lin T, Suttle DP (May 1995). "UMP synthase activity expressed in deficient hamster cells by separate transferase and ...
GLB1
Somatic Cell Genetics. 5 (2): 147-58. doi:10.1007/BF01539157. hdl:2027.42/45554. PMID 113895. S2CID 21896411. Yoshida K, Oshima ... Elastin-derived peptides are chemotactic for some cell types and can alter cell cycle progression. The ability of the GLB1- ... Hinek A, Bodnaruk TD, Bunda S, Wang Y, Liu K (Oct 2008). "Neuraminidase-1, a subunit of the cell surface elastin receptor, ... complex to influence cell proliferation appears to be indirect and involve removal of sialic acid from extracellular and cell ...
NARS (gene)
Somatic Cell Genet. 9 (2): 215-33. doi:10.1007/BF01543178. PMID 6836455. S2CID 42353500. Beaulande M, Tarbouriech N, Hartlein M ... 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. ... doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685. v t e (Articles with short description, Short description ... "Isolation and characterization of interspecific heat-resistant hybrids between a temperature-sensitive chinese hamster cell ...
IDH2
"Human mitochondrial NADP-dependent isocitrate dehydrogenase in man-mouse somatic cell hybrids". Cytogenetics and Cell Genetics ... Shimizu N, Giles RE, Kucherlapati RS, Shimizu Y, Ruddle FH (January 1977). "Somatic cell genetic assignment of the human gene ... IDH2 mutations may allow prolonged survival of glioma and ICC cancer cells, but not AML cells. The reason for this is unknown. ... Somatic Cell Genetics. 3 (1): 47-60. doi:10.1007/BF01550986. PMID 564083. S2CID 32512064. Champion MJ, Brown JA, Shows TB (1979 ...
4F2 cell-surface antigen heavy chain
"Genetic and biochemical characterization of a human surface determinant on somatic cell hybrids: the 4F2 antigen". Somatic Cell ... Somatic Cell Genet. 9 (3): 333-44. doi:10.1007/BF01539142. PMID 6190235. S2CID 22972681. Haynes BF, Hemler ME, Mann DL, ... to its cell surface antigen on dispersed adenomatous parathyroid cells raises cytosolic calcium and inhibits parathyroid ... that induces multinucleated giant cell formation of monocytes and HIV gp160-mediated cell fusion. FRP-1 and 4F2/CD98 are ...
ATP5PF
Somatic Cell Genetics. 8 (2): 223-44. doi:10.1007/BF01538679. PMID 9732751. S2CID 12445064. Wang H, Oster G (Nov 1998). "Energy ... Oster G, Wang H (Mar 2003). "Rotary protein motors". Trends in Cell Biology. 13 (3): 114-21. doi:10.1016/S0962-8924(03)00004-7 ...
Adenosine kinase
... mutation at the adenosine kinase locus in Chinese hamster cells". Somatic Cell Genetics. 4 (6): 715-35. doi:10.1007/BF01543160 ... In cultured mammalian cells, mainly Chinese hamster ovary (CHO) cells, many kinds of mutants that are affected in AdK and show ... high-frequency mutants of CHO cells involve deletions of several introns and exons". DNA and Cell Biology. 20 (1): 53-65. doi: ... "Role of S-adenosylhomocysteine in adenosinemediated toxicity in cultured mouse T lymphoma cells". Cell. 12 (4): 931-8. doi: ...
Thymidine kinase
Köhler G, Pearson T, Milstein C (May 1977). "Fusion of T and B cells". Somatic Cell Genetics. 3 (3): 303-12. doi:10.1007/ ... cells. The negative cells can then be expanded and used for the fusion with TK+ plasma cells. After fusion, the cells are grown ... TK1 is synthesized by the cell during the S phase of cell division. After cell division is completed, TK1 is degraded ... Cells prepare for cell division by making some of the enzymes required during the division. They are not normally present in ...
Leucyl-tRNA synthetase
Somatic Cell Genetics. 6 (5): 667-687. doi:10.1007/BF01538645. PMID 6933703. S2CID 11128003. "Entrez Gene: LARS leucyl-tRNA ... of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". ... corrects the heat sensitive lesion associated with reduced leucyl-tRNA synthetase activity in ts025Cl Chinese hamster cells". ...
PDE4B
Somatic Cell and Molecular Genetics. 20 (2): 75-86. doi:10.1007/BF02290677. PMID 8009369. S2CID 19182571. McLaughlin MM, ... Arp J, Kirchhof MG, Baroja ML, Nazarian SH, Chau TA, Strathdee CA, Ball EH, Madrenas J (Nov 2003). "Regulation of T-cell ... Cytogenetics and Cell Genetics. 69 (1-2): 11-4. doi:10.1159/000133927. PMID 7835077. Bolger GB, Rodgers L, Riggs M (Nov 1994 ... "Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication". ...
PDE4A
Somatic Cell and Molecular Genetics. 20 (2): 75-86. doi:10.1007/BF02290677. PMID 8009369. S2CID 19182571. "PDE4A ... Sullivan M, Egerton M, Shakur Y, Marquardsen A, Houslay MD (Sep 1994). "Molecular cloning and expression, in both COS-1 cells ... Zhou L, Thompson WJ, Potter DE (Jul 1999). "Multiple cyclic nucleotide phosphodiesterases in human trabecular meshwork cells" ( ... expressed in Sf9 cells". Archives of Biochemistry and Biophysics. 394 (1): 54-60. doi:10.1006/abbi.2001.2513. PMID 11566027. ...
Granulocyte colony-stimulating factor
Somatic Cell and Molecular Genetics. 13 (6): 679-84. doi:10.1007/BF01534488. PMID 3499671. S2CID 10909775. Le Beau MM, Lemons ... White blood cells The G-CSF-receptor is present on precursor cells in the bone marrow, and, in response to stimulation by G-CSF ... Another form of rhG-CSF called lenograstim is synthesised in Chinese Hamster Ovary cells (CHO cells). As this is a mammalian ... Deotare U, Al-Dawsari G, Couban S, Lipton JH (September 2015). "G-CSF-primed bone marrow as a source of stem cells for ...
List of OMIM disorder codes
CLCNKA Basal cell carcinoma, somatic; 605462; PTCH1 Basal cell carcinoma, somatic; 605462; PTCH2 Basal cell carcinoma, somatic ... RNF139 Renal cell carcinoma, clear cell, somatic; 144700; OGG1 Renal cell carcinoma, papillary, 1; 605074; PRCC Renal cell ... T cell-negative, B-cell/natural killer-cell positive; 608971; CD3D Severe combined immunodeficiency, T cell-negative, B-cell/ ... T cell-negative, B-cell/natural killer-cell positive; 608971; PTPRC Severe combined immunodeficiency, T-cell negative, B-cell/ ...
CDC27
Somatic Cell and Molecular Genetics. 21 (5): 351-5. doi:10.1007/BF02257470. hdl:2027.42/45546. PMID 8619132. S2CID 9614052. ... "Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells". The Journal of Cell ... "Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells". The Journal of Cell ... Cell division cycle protein 27 homolog is a protein that in humans is encoded by the CDC27 gene. The protein encoded by this ...
PDE4D
Somatic Cell and Molecular Genetics. 20 (2): 75-86. doi:10.1007/BF02290677. PMID 8009369. S2CID 19182571. Baecker PA, Obernolte ... These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including ... cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells". ... cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells". ...
Syndecan 1
Somatic Cell and Molecular Genetics. 16 (5): 501-505. doi:10.1007/BF01233200. PMID 2173154. S2CID 43270934. Mali M, Jaakkola P ... It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood. For plasma ... The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for ... The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and ...
Gabriella Campadelli-Fiume
"Cytogenetics of somatic cell hybrids. I. Progression of stemlines in continuous uncloned cultures of man-mouse cell hybrids". ... HSV entry into the cell Viral assembly in cell HSV exit out of the cell Viral induced alteration of exocytic pathway Herpes ... Coexpression of UL20p and gK Inhibits Cell-Cell Fusion Mediated by Herpes Simplex Virus Glycoproteins gD, gH-gL, and Wild-Type ... Cell Genet. 23 (4): 221-30. doi:10.1159/000131332. PMID 446093. Entry of Herpes Simplex Virus Mediated by Chimeric Forms of ...
Serum amyloid A1
Somatic Cell and Molecular Genetics. 15 (6): 477-501. doi:10.1007/BF01534910. PMID 2595451. S2CID 19607294. Polyak K, Xia Y, ... Cell. 163 (2): 381-93. doi:10.1016/j.cell.2015.08.061. PMC 4621768. PMID 26411290. Ji YR, Kim HJ, Bae KB, Lee S, Kim MO, Ryoo ... Cell. 163 (2): 381-93. doi:10.1016/j.cell.2015.08.061. PMC 4621768. PMID 26411290. Kisilevsky R, Tam SP (2002). "Acute phase ... This finding, which is based on both Saa1/Saa2 knockout mice and ex vivo studies of T cells, strongly suggest a local ...
RNA Helicase A
Somatic Cell and Molecular Genetics. 25 (1): 33-9. doi:10.1023/B:SCAM.0000007138.44216.3a. PMID 10925702. S2CID 29684315. Reddy ... Lee CG, Hurwitz J (Mar 1992). "A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3' to 5' ... Loor G, Zhang SJ, Zhang P, Toomey NL, Lee MY (Dec 1997). "Identification of DNA replication and cell cycle proteins that ... The Journal of Cell Biology. 152 (1): 75-85. doi:10.1083/jcb.152.1.75. PMC 2193649. PMID 11149922. Takasaki Y, Kogure T, ...
Ceruloplasmin
Somatic Cell and Molecular Genetics. 13 (3): 285-92. doi:10.1007/BF01535211. PMID 3474786. S2CID 45686258. Holmberg CG, Laurell ... Experimental Cell Research. 143 (1): 91-102. doi:10.1016/0014-4827(83)90112-X. PMID 6337857. Kressner MS, Stockert RJ, Morell ... and the export of iron from cells for transport through transferrin. Mutations have been known to disrupt the binding of copper ... Molecules and Cells. 20 (2): 167-72. PMID 16267389. "Ceruloplasmin Test: MedlinePlus Medical Test". medlineplus.gov. Retrieved ...
Theodore Puck
Puck was an early pioneer of "somatic cell genetics" and single-cell plating ( i.e. "cloning" .) This work allowed the genetics ... Tjio, J. H.; Puck, Theodore T. (1 August 1958). "Genetics of somatic mammalian cells. II. Chromosomal constitution of cells in ... He developed the CHO cell line from Chinese hamster ovarian cells for this work. These cells are still widely utilized in the ... Puck with the assistance of Philip I. Marcus, successfully cloned a HeLa cell in 1955. Puck made many basic discoveries in ...
Thyrotropin-releasing hormone receptor
Somatic Cell and Molecular Genetics. 19 (6): 577-80. doi:10.1007/BF01233384. PMID 8128317. S2CID 44982871. Duthie SM, Taylor PL ... Somatic Cell and Molecular Genetics. 19 (6): 577-80. doi:10.1007/BF01233384. PMID 8128317. S2CID 44982871. Gershengorn MC (1993 ... The TRHR is found on the cell membrane of thyrotropes of the anterior pituitary. When the TRHR is activated it associates with ... Detection in living cells using bioluminescence resonance energy transfer". The Journal of Biological Chemistry. 276 (16): ...
P2RY1
Somatic Cell and Molecular Genetics. 22 (5): 419-24. doi:10.1007/BF02369897. PMID 9039850. S2CID 28971344. Maier R, Glatz A, ... "The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells". FEBS Letters. ... are involved in calcium signalling in glioma C6 cells". British Journal of Pharmacology. 132 (2): 393-402. doi:10.1038/sj.bjp. ... "ADP-evoked phospholipase C stimulation and adenylyl cyclase inhibition in glioma C6 cells occur through two distinct nucleotide ...