December 2020). "CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells". Signal Transduction and Targeted ... Yurchenko V, O'Connor M, Dai WW, Guo H, Toole B, Sherry B, Bukrinsky M (November 2001). "CD147 is a signaling receptor for ... Yurchenko V, O'Connor M, Dai WW, Guo H, Toole B, Sherry B, Bukrinsky M (November 2001). "CD147 is a signaling receptor for ... June 2002). "Active site residues of cyclophilin A are crucial for its signaling activity via CD147". The Journal of Biological ...

Signal Transduction and Targeted Therapy. 3 (1): 22. doi:10.1038/s41392-018-0025-6. PMC 6107554. PMID 30151243. Wang Y (April ... Some of the oncogenic signaling molecules identified that upregulate TBX3 include TGF-β, BRAF-MAPK, c-Myc, AKT, and PLCᗴ/PKC. ... TBX3 has been functionally connected to the regulation of the Wnt signalling, thereby providing a novel explanation of how ... April 2011). "Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling". The ...

Nunès JA, Truneh A, Olive D, Cantrell DA (January 1996). "Signal transduction by CD28 costimulatory receptor on T cells. B7-1 ... Chang TT, Kuchroo VK, Sharpe AH (2002). "Role of the B7-CD28/CTLA-4 pathway in autoimmune disease". Signal Transduction ... In this case, in the absence of co-stimulatory signals, the interaction of dendritic and T cells leads to T cell anergy. The ... T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of ...

Other Simons' paper, on role of lipid rafts in the signal transduction is second highest cited work and Simons is fourth ... Simons, K.; Toomre, D. (1 October 2000). "Lipid rafts and signal transduction". Nature Reviews. Molecular Cell Biology. 1 (1): ... highest cited scientist in the field of signal transduction. Kai Simons was also recognized by ISI Web of Knowledge, as one of ...

May 2009). "Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors". British ... Signal Transduction and Targeted Therapy. 6 (1): 205. doi:10.1038/s41392-021-00630-3. PMC 8141052. PMID 34023856. Zhuang Y, ... Nishi A, Kuroiwa M, Shuto T (July 2011). "Mechanisms for the modulation of dopamine d(1) receptor signaling in striatal neurons ...

Allosteric mechanisms of signal transduction. Science (2005), 308: 1424-1428 Stuart J Edelstein, Olivier Schaad, Eric Henry, ...

Signal Transduction and Targeted Therapy. 6 (1): 201. doi:10.1038/s41392-021-00572-w. PMC 8165101. PMID 34054126. Curigliano G ... This signal pathway regulates cellular functions such as growth and survival. It is strictly regulated in healthy cells, but is ... Hoxhaj G, Manning BD (February 2020). "The PI3K-AKT network at the interface of oncogenic signalling and cancer metabolism". ...

Signal Transduction and Targeted Therapy. 5 (1): 8. doi:10.1038/s41392-020-0110-5. ISSN 2059-3635. PMC 7005297. PMID 32296030. ... Phoenix rising is a process by which dead cells send signals that promote growth and division, generating new cells. After a ... Through the process of apoptosis, the dying tumor cells provide growth signals and repair radiation-damaged tumors. PGE2 is ... Targeting CSC surface markers, the ABC cascade, the microenvironment, or signal cascades could all help kill CSCs. There are ...

Signal Transduction and Targeted Therapy. 5 (1): 72. doi:10.1038/s41392-020-0186-y. PMC 7239890. PMID 32435053. Hou X, Sun M, ... as the contribution of other sample components to mass spectrometer noise can drown out relevant signal. Therefore, SPROX ...

Bacterial swimming is used in bacterial taxis (mediated by specific receptors and signal transduction pathways) for the ... Parkinson, John S. (1993). "Signal transduction schemes of bacteria". Cell. 73 (5): 857-871. doi:10.1016/0092-8674(93)90267-t. ... Chemoreceptors detect attractants or repellents and stimulate responses through a signalling cascade that controls the ...

Partch, Carrie (2006). "Signal Transduction Mechanisms of Cryptochrome". {{cite journal}}: Cite journal requires ,journal= ( ... Following Partch's earliest research at OHSU, she began to home in on cryptochrome proteins and their signal transduction ... Partch's PhD research focused on signal transduction mechanisms by cryptochrome proteins. In her post-doctoral research, Partch ... "Role of Structural Plasticity in Signal Transduction by the Cryptochrome Blue-Light Photoreceptor". Biochemistry. 44 (10): 3795 ...

"Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities". Signal Transduction and Targeted ...

Thus, conventional and novel PKCs are activated through the same signal transduction pathway as phospholipase C. On the other ... Biancani P, Harnett KM (2006). "Signal transduction in lower esophageal sphincter circular muscle, PART 1: Oral cavity, pharynx ... Serine/threonine-specific protein kinase Signal transduction Yasutomi Nishizuka, discovered protein kinase C Ccdc60 Wilson CH, ... CARD-CC signal transduction nodes". The FEBS Journal. 288 (5): 1630-1647. doi:10.1111/febs.15522. ISSN 1742-4658. PMID 32790937 ...

They are indispensable for signal transduction and cell regulation, often via kinases and phosphatases. They also generate ... ISBN 978-981-4463-92-8. Krauss G (2003). "The Regulations of Enzyme Activity". Biochemistry of Signal Transduction and ... Changeux JP, Edelstein SJ (June 2005). "Allosteric mechanisms of signal transduction". Science. 308 (5727): 1424-1428. Bibcode: ... Tsai CJ, Del Sol A, Nussinov R (March 2009). "Protein allostery, signal transmission and dynamics: a classification scheme of ...

Signal Transduction and Targeted Therapy. 6 (1): 206. doi:10.1038/s41392-021-00642-z. ISSN 2059-3635. PMC 8149719. PMID ...

Wang, Nian; Wu, Runliu; Tang, Daolin; Kang, Rui (2021-01-19). "The BET family in immunity and disease". Signal Transduction and ... Bromodomains, as the "readers" of lysine acetylation, are responsible in transducing the signal carried by acetylated lysine ...

Bulcha, J (2021). "Viral vector platforms within the gene therapy landscape". Signal Transduction and Targeted Therapy. 6 (1): ... Analogous to the way computers operate through electronic signals, cells process and transmit information through molecules. ... Vector engineering can increase AAV transduction efficiency (by optimizing the transgene cassette), vector tropism (using ... also known as protein transduction domains (PTDs) Ligand conjugates Protein or Sugar based nanoassemblies (e.g. Chitosan) ...

Cheng G, Schoenberger SP (2002). "CD40 signaling and autoimmunity". Signal Transduction Pathways in Autoimmunity. Current ... In the macrophage, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L (CD154) ... Ni CZ, Welsh K, Leo E, Chiou CK, Wu H, Reed JC, Ely KR (September 2000). "Molecular basis for CD40 signaling mediated by TRAF3 ... Furthermore, many features and purposes of the CD40 signaling pathway in B cells were made determined to the detection of CD40 ...

Liu T, Zhang L, Joo D, Sun SC (14 July 2017). "NF-κB signaling in inflammation". Signal Transduction and Targeted Therapy. 2 (1 ... Among the PRRs, TLRs play a major role in signal transduction leading to cytokine production. The binding of MAMPs to TLR ... Forman HJ, Torres M (December 2002). "Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling". ... Macrophages supply both signals required for T helper cell activation: 1) Macrophages present antigen peptide-bound MHC class ...

Signal Transduction and Targeted Therapy. 7 (1): 91. doi:10.1038/s41392-022-00952-w. PMC 8931182. PMID 35304437. Xiao M, Li J, ...

Fleming I, Busse R (Aug 1999). "Signal transduction of eNOS activation". Cardiovascular Research. 43 (3): 532-41. doi:10.1016/ ... Collins B, Davis M, Hancock J, Parton R (Jun 2012). "Structure-based Reassessment of the Caveolin Signaling Model: Do Caveolae ... NOS3 variants may also affect the responses to drugs that affect NO signaling, such as statins, angiotensin-converting enzyme ... Lisanti MP, Scherer PE, Tang Z, Sargiacomo M (Jul 1994). "Caveolae, caveolin and caveolin-rich membrane domains: a signalling ...

Signal Transduction and Targeted Therapy. 5 (1): 269. doi:10.1038/s41392-020-00372-8. PMC 7670843. PMID 33203855. Flower, ... It is a type I transmembrane protein with an N-terminal signal peptide, an ectodomain that has an immunoglobulin fold, and a C- ... terminal endoplasmic reticulum retention signal sequence. The structure contains seven beta strands which form two beta sheets ...

Signal Transduction in the Retina. CRC Press. pp. 273-. ISBN 978-1-4200-0716-9. Thiriet M (14 December 2011). Signaling at the ... These receptors bind growth factor and cytokine signaling proteins in the TGF-beta family such as TGFβs (TGFβ1, TGFβ2, TGFβ3), ... In the transduction pathway, ligand-bound type II receptors activate type I receptors by phosphorylation, which then ... December 1992). "TGF beta signals through a heteromeric protein kinase receptor complex". Cell. 71 (6): 1003-14. doi:10.1016/ ...

... and is important for signal transduction. The Dsh protein functions both in planar polarity and Wnt signalling, where it ... Gammons M, Bienz M (April 2018). "Multiprotein complexes governing Wnt signal transduction". Current Opinion in Cell Biology. ... Schwarz-Romond T, Merrifield C, Nichols BJ, Bienz M (November 2005). "The Wnt signalling effector Dishevelled forms dynamic ... Case LB, Ditlev JA, Rosen MK (May 2019). "Regulation of Transmembrane Signaling by Phase Separation". Annual Review of ...

TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB ... Schneider C, Hübinger G (Jul 2002). "Pleiotropic signal transduction mediated by human CD30: a member of the tumor necrosis ... Horie R, Higashihara M, Watanabe T (Jan 2003). "Hodgkin's lymphoma and CD30 signal transduction". International Journal of ... Kurts C, Carbone FR, Krummel MF, Koch KM, Miller JF, Heath WR (Mar 1999). "Signalling through CD30 protects against autoimmune ...

Soh UJ, Dores MR, Chen B, Trejo J (May 2010). "Signal transduction by protease-activated receptors". British Journal of ... thus resensitizing the cell to thrombin and resetting the signal transduction pathway. Finding selective agonists for PAR1 has ... Chen B, Siderovski DP, Neubig RR, Lawson MA, Trejo J (January 2014). "Regulation of protease-activated receptor 1 signaling by ... This internalization and degradation process is necessary for the termination of receptor signaling. In order to regain ...

Gerhard Krauss (2008). Biochemistry of signal transduction and regulation. Wiley-VCH. pp. 235-. ISBN 978-3-527-31397-6. ... Small GTPases act as molecular switches in signaling pathways, which act to regulate functions of other proteins. They are ... The rate of GTP hydrolysis for small GTPases is generally too slow to create physiologically relevant transient signals, and ...

This signal transduction is not crucial. Activation of cell effector mechanisms trough IL-33/ST2 is present also in TRAF6 ... This cardioprotective IL-33 signal is counterbalanced by the level of soluble ST2, which binds IL-33 and makes it unavailable ... "Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N- ... an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated ...

Schwartz MA, Schaller MD, Ginsberg MH (1995). "Integrins: emerging paradigms of signal transduction". Annual Review of Cell and ... Akiyama SK, Yamada SS, Yamada KM, LaFlamme SE (Jun 1994). "Transmembrane signal transduction by integrin cytoplasmic domains ... Integrins link the actin cytoskeleton with the extracellular matrix and they transmit signals bidirectionally between the ... Burridge K, Chrzanowska-Wodnicka M (1996). "Focal adhesions, contractility, and signaling". Annual Review of Cell and ...

Cebulla CM, Miller DM, Sedmak DD (2000). "Viral inhibition of interferon signal transduction". Intervirology. 42 (5-6): 325-30 ... define a gene family involved in signal transduction". Proceedings of the National Academy of Sciences of the United States of ... "The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals". The EMBO Journal. ... Signal transducer and activator of transcription 2 is a protein that in humans is encoded by the STAT2 gene. It is a member of ...