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*  Protein S
... homologous to plasma steroid hormone-binding proteins such as sex hormone-binding globulin and corticosteroid-binding globulin ... In the circulation, Protein S exists in two forms: a free form and a complex form bound to complement protein C4b-binding ... Griffin JH, Gruber A, Fernández JA (1992). "Reevaluation of total, free, and bound protein S and C4b-binding protein levels in ... Protein S also binds to the nascent complement complex C5,6,7 and prevents this complex from inserting into a membrane. This ...
*  Sex hormone-binding globulin
... (SHBG) or sex steroid-binding globulin (SSBG) is a glycoprotein that binds to the two sex hormones ... If HNF4A level is low then COUP-TF binds to the first site and turns off production of SHBG. Sex hormone-binding globulin is ... Selva DM, Hammond GL (Jul 2009). "Thyroid hormones act indirectly to increase sex hormone-binding globulin production by liver ... Rosner W, Hryb DJ, Khan MS, Nakhla AM, Romas NA (1999). "Sex hormone-binding globulin mediates steroid hormone signal ...
*  Segesterone acetate
... is bound to albumin. It does not bind to sex hormone-binding globulin. Segesterone acetate, also known as ... It does not bind significantly to the androgen receptor, estrogen receptor, or mineralocorticoid receptor. Segesterone acetate ... A.R. Genazzani (15 May 2001). Hormone Replacement Therapy and Cardiovascular Disease: The Current Status of Research and ...
*  Sexual dimorphism
"Diverse Roles for Sex Hormone-Binding Globulin in Reproduction". biolreprod.org. Cordelia Fine (August 2010). Delusions of ... male fetuses may be shielded from the masculinizing effects of androgen through the action of sex-hormone binding globulin. The ... Bateman's principle Sex differences List of homologues of the human reproductive system Sex differences in humans Sex ... "because it is easier to manipulate hormone levels than the expression of sex chromosome genes, the effects of hormones have ...
*  Steroid hormone receptor
Rosner W, Hryb DJ, Kahn SM, Nakhla AM, Romas NA (Mar 2010). "Interactions of sex hormone-binding globulin with target cells". ... Sex hormones: Progesterone) 4: Androgen receptor (AR; NR3C4, AR) (Sex hormones: Testosterone) Intracellular steroid hormone ... Sex hormone-binding globulin (SHBG) is thought to mainly function as a transporter and reservoir for the estradiol and ... binds Thyroid hormone (though not technically steroid hormones, thyroid hormones can be grouped here because their receptors ...
*  3,4-Divanillyltetrahydrofuran
The compound has been found to occupy binding sites of sex hormone-binding globulin (SHBG), thereby reducing the ability of ... Schöttner M; Gansser D; Spiteller G. (1997). "Interaction of lignans with human sex hormone binding globulin (SHBG)". Z ... SHBG to bind additional steroid hormones such as estrogens and androgens, mostly testosterone and estradiol. Certain extracts ...
*  Testosterone
In plasma, 98% of testosterone is bound to protein, with 65% bound to sex hormone-binding globulin (SHBG) and 33% bound weakly ... Cumming DC, Wall SR (November 1985). "Non-sex hormone-binding globulin-bound testosterone as a marker for hyperandrogenism". ... sex hormone-binding globulin (SHBG). In males, testosterone is synthesized primarily in Leydig cells. The number of Leydig ... the male sex hormone, into estradiol, the female sex hormone. However no clear association between body mass index and ...
*  Hypertrichosis
One medicinal option suppresses testosterone by increasing the sex hormone-binding globulin. Another controls the ... Hypertrichosis is diagnosed clinically by the occurrence of hair in excess of what is expected for age, sex, and ethnicity in ... It is linked to excessive male hormones in women, thus symptoms may include acne, deepening of the voice, irregular menstrual ... Increases in androgen (male hormone) levels are the primary cause of most hirsutism cases. If caused by increased levels of ...
*  Benign prostatic hyperplasia
... gonadotrophins and sex hormone-binding globulin in prostatic hyperplasia". Annals of Saudi Medicine. 28 (3): 174-8. doi:10.4103 ... "Serum sex hormones and measures of benign prostatic hyperplasia". The Prostate. 61 (2): 124-31. doi:10.1002/pros.20080. PMID ... Estrogen has a key role in the growth of cells in the prostate and DHT is an anabolic hormone many times more potent than ... In both of these cell types, DHT binds to nuclear androgen receptors and signals the transcription of growth factors that are ...
*  Steroid hormone
... bound to specific carrier proteins such as sex hormone-binding globulin or corticosteroid-binding globulin. Further conversions ... Some examples are sex hormone-binding globulin (SHBG), corticosteroid-binding globulin, and albumin. Most studies say that ... A steroid hormone is a steroid that acts as a hormone. Steroid hormones can be grouped into two classes: corticosteroids ( ... and then bind to steroid hormone receptors (which may be nuclear or cytosolic depending on the steroid hormone) to bring about ...
*  Androgen-binding protein
Sex hormone-binding globulin (SHBG) Androgen-Binding Protein at the US National Library of Medicine Medical Subject Headings ( ... ABP has the same amino acid sequence as sex hormone-binding globulin (SHBG); the difference is the site of production and the ... Because ABP binds to T and DHT, these hormones are made less lipophilic and become concentrated within the luminal fluid of the ... Androgen-binding protein (ABP) is a glycoprotein (beta-globulin) produced by the Sertoli cells in the seminiferous tubules of ...
*  Free androgen index
Instead around half is tightly bound to sex hormone binding globulin, and the other half is weakly bound to albumin. Only a ... The ratio is the total testosterone level divided by the sex hormone binding globulin (SHBG) level, and then multiplying by a ... "Empirical estimation of free testosterone from testosterone and sex hormone-binding globulin immunoassays". Eur. J. Endocrinol ... Since only the free testosterone is able to bind to tissue receptors to exert its effects, it is believed that free ...
*  SNAPAP
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". The Journal of ... Snapin has been established to be a promoter of vesicle docking, as it plays a role in binding to SNAP-25, which together ... "Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin". Human Molecular Genetics. 15 (20): 3041-54. doi: ... "Identification and characterization of Snapin as a ubiquitously expressed SNARE-binding protein that interacts with SNAP23 in ...
*  FLOT1
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem ...
*  SORD
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem ... 1993). "Membrane-bound sorbitol dehydrogenase in human red blood cells. Studies in normal subjects and in enzyme-deficient ...
*  UBE2O
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem ... Characterization of a coiled-coil copine-binding motif". J. Biol. Chem. 278 (12): 10048-54. doi:10.1074/jbc.M212632200. PMID ...
*  APEH (gene)
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem ... 1991). "Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but ...
*  SRI (gene)
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". The Journal of ... Wang SL, Tam MF, Ho YS, Pai SH, Kao MC (February 1995). "Isolation and molecular cloning of human sorcin a calcium-binding ... Brownawell AM, Creutz CE (August 1997). "Calcium-dependent binding of sorcin to the N-terminal domain of synexin (annexin VII ... Brownawell AM, Creutz CE (August 1997). "Calcium-dependent binding of sorcin to the N-terminal domain of synexin (annexin VII ...
*  EIF3F
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem ... Possible roles in RNA binding and macromolecular assembly". J. Biol. Chem. 272 (43): 27042-52. doi:10.1074/jbc.272.43.27042. ...
*  MXD4
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". The Journal of ... The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex ... "Human liver specific transcriptional factor TCP10L binds to MAD4". Journal of Biochemistry and Molecular Biology. 37 (4): 402-7 ...
*  APOBEC3C
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". The Journal of ... The crystal structure of A3C suggests a putative HIV-1 vif binding region. A3C was found to inhibit LINE-1 elements by directly ... "The APOBEC3C crystal structure and the interface for HIV-1 Vif binding". Nature Structural & Molecular Biology. 19 (10): 1005- ... "Vif Proteins from Diverse Human Immunodeficiency Virus/Simian Immunodeficiency Virus Lineages Have Distinct Binding Sites in ...
*  PSTPIP2
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem ... cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase". J Biol Chem. 273 (46): 30487-96. doi: ...
*  NOMO1
"Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin". J. Steroid Biochem ... Haffner C, Frauli M, Topp S, Irmler M, Hofmann K, Regula JT, Bally-Cuif L, Haass C (Aug 2004). "Nicalin and its binding partner ...
*  Polycystic ovary syndrome
The oral contraceptives increase sex hormone binding globulin production, which increases binding of free testosterone. This ... The Free androgen index (FAI) of the ratio of testosterone to sex hormone-binding globulin (SHBG) is high and is meant to be a ... There are often low levels of sex hormone-binding globulin, in particular among obese or overweight women.[citation needed] ... The ratio of LH (Luteinizing hormone) to FSH (Follicle-stimulating hormone), when measured in international units, is elevated ...
*  Estrogen (medication)
Estrogens are typically bound to albumin and/or sex hormone-binding globulin in the circulation. They are metabolized in the ... levels to castrate concentrations and decreasing free testosterone levels by increasing sex hormone-binding globulin (SHBG) ... They are one of three types of sex hormone agonists, the others being androgens/anabolic steroids like testosterone and ... Oh DM, Phillips, TJ (2006). "Sex Hormones and Wound Healing". Wounds. 18 (1): 8-18. MedlinePlus DrugInfo medmaster-a682922. ...
*  7α-Thioprogesterone
... and shows very low binding to sex hormone-binding globulin (SHBG) but high affinity for corticosteroid-binding globulin (CBG) ... interaction of 70 drugs with testosterone-binding globulin and corticosteroid-binding globulin in human plasma". J. Clin. ... Pugeat MM, Dunn JF, Nisula BC (1981). "Transport of steroid hormones: ... The drug has also been assessed at steroid hormone-associated carrier proteins, ...
*  Anordrin
Song S, Chen JK, He ML, Zuo SH, Fotherby K (1987). "Effect of Anordrin on serum levels of sex hormone binding globulin, ... It binds to the estrogen receptor but does not bind to the androgen receptor or the progesterone receptor. In animals, anordrin ... and A-homo-5 alpha-androstane derivatives with the androgen receptor and the epididymal androgen-binding protein". Steroids. 37 ...