A decrease in antibodies (also known as immune globulins) may lead to an increased susceptibility to infections. And the loss ... Therefore, it is useful to categorize patients based on their serum albumin levels, if less than normal (typically less than ... serum). Congenital molecular abnormalities, or dysfunctional lymphatic drainage might cause epithelial matrix changes. ...

Lipid-soluble hormones must bond to carrier plasma glycoproteins (e.g., thyroxine-binding globulin (TBG)) to form ligand- ... For instance, high blood sugar (serum glucose concentration) promotes insulin synthesis. Insulin then acts to reduce glucose ... as well as binding globulins Neurons and mental activity Environmental changes, e.g., of light or temperature One special group ...

Two precursor oligosaccharides exist, type 1 and type 2. Type 1 is found in secretions and in the serum. Type 2 is found ... Lewis antibodies are generally reactive at room temperature and only occasionally at 37 C and AHG phase (antihuman globulin). ... both free in serum and in secretions) to make the Le(a) antigen. The le gene is an amorph. The Lewis antigen produced on free ... shed their Lewis antigens and acquire the Lewis phenotype of the recipient Lewis antibodies are quickly adsorbed by free serum ...

"Bound" Globulin in the skin of patients with chronic discoid lupus erythematosus", The Lancet, 7 March 1964, PMID 14100191, pp ... He authored many articles on enzyme histochemical studies of the skin and nephelometric studies of serum in drug allergy ... "Bound globulin in the skin of patients with chronic discoid lupus erythematosus and systemic lupus erythematosus". He pioneered ...

Negative sera from patients with other autoimmune diseases (systemic lupus erythematosus, rheumatoid arthritis, and multiple ... Treatment often includes a course of antithymocyte globulin (ATG) and several months of treatment with ciclosporin to modulate ... First-line treatment for aplastic anemia consists of immunosuppressive drugs-typically either anti-lymphocyte globulin or anti- ... Corticosteroids are generally ineffective, though they are used to ameliorate serum sickness caused by ATG. Normally, success ...

It is a barrier to blood proteins such as albumin and globulin. The part of the podocyte in contact with the glomerular ... that repels negatively charged molecules such as serum albumin. The mesangium is a space which is continuous with the smooth ... and blood proteins such as albumin and globulin. Underlying causes for glomerular injury can be inflammatory, toxic or ...

Constans J, Oksman F, Viau M (August 1981). "Binding of the apo and holo forms of the serum vitamin D-binding protein to human ... Human GC is a glycosylated alpha-globulin, ~58 kDa in size. Its 458 amino acids are coded for by 1690 nucleotides on chromosome ... Svasti J, Kurosky A, Bennett A, Bowman BH (April 1979). "Molecular basis for the three major forms of human serum vitamin D ... Cooke NE, David EV (December 1985). "Serum vitamin D-binding protein is a third member of the albumin and alpha fetoprotein ...

Classical approach is to incubate antibodies with target cells and source of complement (serum). Then cell death is determined ... adding antihuman globulin (AHG), removing unbound antibodies before adding complement, separation of T cell and B cell subset. ... The basic version involves incubation of patient's serum with donor's lymphocytes and second incubation after adding rabbit ...

However, reaching an effective serum concentration of acyclovir typically requires intravenous administration, making its use ... zoster-immune globulin (ZIG), and vidarabine. Acyclovir is frequently used as the drug of choice in primary VZV infections, and ...

It has also been shown that conjugation of some drugs to the Fc region of IgG or serum albumin to generate fusion proteins ... "Endocytosis of hepatitis B immune globulin into hepatocytes inhibits the secretion of hepatitis B virus surface antigen and ... Ghetie V, Hubbard JG, Kim JK, Tsen MF, Lee Y, Ward ES (March 1996). "Abnormally short serum half-lives of IgG in beta 2- ... May 2014). "Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding". The Journal of Biological ...

... interaction of 70 drugs with testosterone-binding globulin and corticosteroid-binding globulin in human plasma". J. Clin. ... steady-state serum levels of the sulfur-containing metabolites". J Clin Pharmacol. 29 (4): 342-7. doi:10.1002/j.1552-4604.1989. ... A study assessed the interaction of spironolactone and 7α-TS with sex hormone-binding globulin and found that they had very low ... steady-state serum levels of the sulfur-containing metabolites". J Clin Pharmacol. 29 (4): 342-7. doi:10.1002/j.1552-4604.1989. ...

... and the addition of anti-human globulin (AHG) reagent. Anti-human globulin is an antibody directed against human IgG antibodies ... Indirect antiglobulin testing is used to detect antibodies in plasma/serum, whereas direct antiglobulin testing is used to ... system antigens and their characteristics must be identified when such antibodies are detected in a potential recipient's serum ...

The Vroman effect, named after Leo Vroman, describes the process of competitive protein adsorption to a surface by blood serum ... Under stagnant conditions initial protein deposition takes place in the sequence: albumin; globulin; fibrinogen; fibronectin; ...

Antithymocyte globulin (ATG) was originally developed as one of various tested preparations of antilymphocyte globulin (ALG) ... Since the discovery of a link between antilymphocyte serum (ALS) and lymphocyte depletion by Metchnikoff in 1899, various ... leading to testing of ATG derived from rabbit serum. Thymoglobulin was the first commercial rabbit-derived ATG to be introduced ... "Rabbit Antithymocyte Globulin (Thymoglobulin®)". Drugs. 70 (6): 691-732. doi:10.2165/11315940-000000000-00000. ISSN 0012-6667. ...

"The relationship between serum levels of insulin and sex hormone-binding globulin in men: The effect of weight loss". The ... Circulating serum levels of IGF-1 are increased with vertex balding, although this study did not look at mRNA expression at the ... Serum indices of hepatic function and surrogate markers for diabetes, previously used, show less correlation with SHBG by ... Zhang Y, Xu J, Jing J, Wu X, Lv Z (October 2018). "Serum Levels of Androgen-Associated Hormones Are Correlated with Curative ...

In the winter rainy season, there is an increase in blood urea nitrogen, albumin, and globulin. Some components of the blood ... Most hematological, serum biochemical, and electrolyte values are consistent between males and females. However, females have ... significantly higher red blood cell counts, hematocrit, total leucocyte (white blood cell) counts, and total serum bilirubin ...

Chemical similarities to polypetide chains of myeloma globulins and normal gamma-globulins". The Journal of Experimental ... Von Behring and Kitasato put forward the theory of humoral immunity, proposing that a mediator in serum could react with a ... Conversely, most gamma-globulins are antibodies, which is why the two terms were historically used as synonyms, as were the ... Rho(D) immune globulin antibodies are specific for human RhD antigen. Anti-RhD antibodies are administered as part of a ...

Siber also developed Cytogam, the first Cytomegalovirus immune Globulin, BabyBIG, the first infant botulism immune globulin, ... Shahid, NS; Steinhoff, MC; Hoque, SS; Begum, T; Thompson, C; Siber, GR (November 11, 1995). "Serum, breast milk, and infant ... Dagan, R; Givon-Lavi, N; Fraser, D; Lipsitch, M; Siber, GR; Kohberger, R (August 1, 2005). "Serum serotype-specific ... "Respiratory syncytial virus-enriched globulin for the prevention of acute otitis media in high risk children". The Journal of ...

Khan MA, Kumar Y, Tayyab S (2003). "Bilirubin binding properties of pigeon serum albumin and its comparison with human serum ... and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and ... Nishio H, Dugaiczyk A (1996). "Complete structure of the human alpha-albumin gene, a new member of the serum albumin multigene ... Nishio H, Heiskanen M, Palotie A, Bélanger L, Dugaiczyk A (1996). "Tandem arrangement of the human serum albumin multigene ...

I: Demonstration of antibrain globulins by fluorescent antibody techniques. Arch Gen Psychiat 16: 1-9. (Schizophrenia, Blood ... the substance obtained from serum of patients with schizophrenia. Am J Psychiatry 114: 917-919 1958 Time, April 13, 1953, [1]) ...

Pathological jaundice in newborns should be suspected when the serum bilirubin level rises by more than 5 mg/dL per day, serum ... It is the main constituent of total protein (the remaining constituents are primarily globulins). Albumin levels are decreased ... When the total serum bilirubin increases over 95th percentile for age during the first week of life for high risk babies, it is ... Serum NT levels are higher during 2nd and 3rd trimesters in pregnancy. Ceruloplasmin is an acute phase protein synthesized in ...

... a ceruloplasmin-like protein which is immunologically similar to serum ceruloplasmin. The occluding junctions of Sertoli cells ... also called testosterone-binding globulin) increases testosterone concentration in the seminiferous tubules to lightly ...

Blood serum tests can also provide useful information about the osmolality of the body's extracellular fluids. A decrease in ... such as in patients with autoimmune chronic hepatitis with severely elevated globulin levels. Psychogenic polydipsia is an ... and can on rare occasions be life-threatening as the body's serum sodium level is diluted to an extent that seizures and ... osmolality caused by excess water intake will decrease the serum concentration of red blood cells, blood urea nitrogen (BUN), ...

This technique demonstrated that a rabbit antibody against human globulin would induce agglutination of human red cells "coated ... In 1904, Donath and Landsteiner suggested a serum factor was responsible for hemolysis in paroxysmal cold hemoglobinuria. ... they demonstrated the presence of abnormal hemolysins in the sera of patients with acquired hemolytic anemia and postulated an ... Increased red cell breakdown Elevated serum bilirubin (unconjugated) Excess urinary urobilinogen Reduced plasma haptoglobin ...

High-dose intravenous gamma-globulin has also been suggested for the treatment of severe eczema in patients with HIES and ... described two boys with similar symptoms as well as coarse facies, eosinophilia, and elevated serum IgE levels. These two ... Kimata H (March 1995). "High-dose intravenous gamma-globulin treatment for hyperimmunoglobulinemia E syndrome". The Journal of ... concentrations of the serum antibody IgE. Inheritance can be autosomal dominant or autosomal recessive. Many patients with ...

I]n 1944 [he] identified a rare condition in which two patients experienced a thickening of their blood serum, bleeding of the ... globulin. Waldenström's entry on "Who Named It" Robert A. Kyle and Kenneth C. Anderon, "A Tribute to Jan Gosta Waldenström", ...

Factor VII (also known as serum prothrombin conversion accelerator or proconvertin, precipitated by barium sulfate) was ... it was identified in the 1950s and is alternatively called antihemophilic globulin due to its capability to correct hemophilia ...

Kyne, L; Warndy, M; Qamar, A; Kelly, CP (10 February 2000). "Asymptomatic carriage of Clostridum difficile and serum levels of ... "Treatment with intravenously administered gamma globulin of chronic relapsing colitis induced by Clostridium difficile toxin". ...

Those with myeloma will typically display a rouleaux formation on a peripheral smear and a large globulin gap, indicative of a ... "VISCS Clinical Viscosity Serum Test". Mayoclinic. May 1, 1995. Archived from the original on November 4, 2019. Retrieved ... Blood transfusions should be used with caution as they can increase serum viscosity. Hydration is a temporizing measure to ... Even after treatment, the condition will recur unless the underlying disorder is treated.[citation needed]Serum viscosity and ...

Other signs of metabolic syndrome include high blood pressure, decreased fasting serum HDL cholesterol, elevated fasting serum ... low testosterone-binding globulin) in men can be attributed to metabolic syndrome. Various strategies have been proposed to ... high serum triglycerides, and low serum high-density lipoprotein (HDL). Metabolic syndrome is associated with the risk of ... Kogiso T, Moriyoshi Y, Shimizu S, Nagahara H, Shiratori K (2009). "High-sensitivity C-reactive protein as a serum predictor of ...