Signs and symptoms of Parkinson's disease
The association of serotonin with mood and cognition may explain some of the side-effects observed in patients treated with L- ... doi:10.1016/j.neuropharm.2012.11.010 Stansley, B. J., & Yamamoto, B. K. (2015). L-Dopa and Brain Serotonin System Dysfunction. ... Dopa due to serotonin deficit. In most cases, motor symptoms predominate at early PD stages, while cognitive disturbances (such ... specifically the frontal lobe as well as those areas that produce serotonin, norepinephrine and dopamine), depression may ...
Zusanli
List of acupuncture points Dimitrov, N; Atanasova, D; Tomov, N; Sivrev, D; Lazarov, N (2017). "Acupuncture causes serotonin ... Acupuncture of Zusanli induces local serotonin release. Furthermore, the stimulation of this acupoint is shown to decrease ... muscarinic cholinergic receptors and serotonin receptors 5-HT1a and 5-HT3, was repeatedly evidenced. The stimulation of Zusanli ...
Ergotism
ISBN 0-8204-3354-3.[page needed] Eadie M. J. (July 2003). "Convulsive ergotism: epidemics of the serotonin syndrome?". Lancet ...
Talbina
Tsampa "Serotonin: Function, uses, SSRIs, and sources". 11 November 2020. Scully, Terence; Dumville, DN (1997). The art of ... and thus serotonin in the body. Ibn Sina, in his 11th century work The Canon of Medicine, wrote of the healing effects of ...
Pipamperone
... has low and likely insignificant affinity for the H1 and mACh receptors, as well as for other serotonin and ... Niemegeers CJ, Awouters F, Janssen PA (1990). "[Serotonin antagonism involved in the antipsychotic effect. Confirmation with ... due to its prominent serotonin antagonism. It is also used to normalise mood and sleep patterns and has antianxiety effects in ...
Seasonal affective disorder
One possibility is that SAD is related to a lack of serotonin, and serotonin polymorphisms could play a role in SAD, although ... Mice incapable of turning serotonin into N-acetylserotonin (by serotonin N-acetyltransferase) appear to express "depression- ... 5-HTP (an amino acid that helps to produce serotonin, and is often used to help those with depression) has also been suggested ... SSRI (selective serotonin reuptake inhibitor) antidepressants have proven effective in treating SAD. Effective antidepressants ...
Central nervous system fatigue
The increased synthesis of brain serotonin occurs because of a higher proportion of tryptophan, the serotonin precursor, in the ... serotonin (5-HT), noradrenaline, and dopamine. The roles of dopamine, noradrenaline, and serotonin in CNS fatigue is unclear, ... In the brain, serotonin is a neurotransmitter and regulates arousal, behavior, sleep, and mood, among other things. During ... Manipulations of serotonin and, especially, noradrenaline, have the opposite effect and force subjects to decrease power output ...
Dopamine reuptake inhibitor
Kintscher, U (2012). "Reuptake Inhibitors of Dopamine, Noradrenaline, and Serotonin". Reuptake Inhibitors of Dopamine, ... with little to no effect on the norepinephrine or serotonin transporters) Armodafinil (R-enantiomer of modafinil; somewhat more ...
Ergine
"Serotonin and serotonin receptors in hallucinogen action". Handbook of the Behavioral Neurobiology of Serotonin. Handbook of ... Ergine interacts with serotonin, dopamine, and adrenergic receptors similarly to but with lower affinity than lysergic acid ... diethylamide (LSD). The psychedelic effects of ergine can be attributed to activation of serotonin 5-HT2A receptors. The ...
Venlafaxine
An abortive serotonin syndrome state, in which some but not all of the symptoms of the full serotonin syndrome are present, has ... The development of a potentially life-threatening serotonin syndrome (also classified as "serotonin toxicity") may occur with ... and triptans and with drugs that impair metabolism of serotonin (including MAOIs)[citation needed]. Serotonin syndrome symptoms ... As with other serotonin reuptake inhibitors (SRIs), these effects are generally short-lived, lasting only 3 to 5 days, and ...
PNU-142633
The serotonin system : history, neuropharmacology, and pathology. M. D. Tricklebank, Eileen Daly. London, United Kingdom. 2019 ... Serotonin receptor antagonists, Phenylpiperazines, Benzamides, Isochromenes, All stub articles, Nervous system drug stubs). ...
Matthew Koma
Medved, Matt (May 29, 2014). "Code First Play: Audien & Matthew Koma, 'Serotonin'". Billboard. Woodruff, Chase (May 22, 2014 ... "Serotonin". Also in May 2014, Afrojack's album Forget the World, which featured two songs written and sung by Koma, "Keep our ...
Migraine
Low levels of the neurotransmitter serotonin, also known as 5-hydroxytryptamine (5-HT), are also believed to be involved. ... Hamel E (November 2007). "Serotonin and migraine: biology and clinical implications". Cephalalgia. 27 (11): 1293-300. doi: ...
7-Chloro-AMT
... though several closely related compounds are known to act as serotonin-dopamine releasing agents and agonists of the 5-HT2A ... Serotonin receptor agonists, Chloroarenes, All stub articles, Nervous system drug stubs). ... "Alpha-ethyltryptamines as dual dopamine-serotonin releasers". Bioorganic & Medicinal Chemistry Letters. 24 (19): 4754-4758. doi ...
Major depressive disorder
A 2022 review found no consistent evidence supporting the serotonin hypothesis, linking serotonin levels and depression. Immune ... Andrews PW, Bharwani A, Lee KR, Fox M, Thomson JA (April 2015). "Is serotonin an upper or a downer? The evolution of the ... July 2022). "The serotonin theory of depression: a systematic umbrella review of the evidence". Mol Psychiatry. doi:10.1038/ ... Zisook S, Rush AJ, Haight BR, Clines DC, Rockett CB (February 2006). "Use of bupropion in combination with serotonin reuptake ...
Alexithymia
The 5-HTTLPR region on the serotonin transporter gene influences the transcription of the serotonin transporter that removes ... Kano M, Mizuno T, Kawano Y, Aoki M, Kanazawa M, Fukudo S (1 January 2012). "Serotonin transporter gene promoter polymorphism ... Another study examining the 5-HT1A receptor, a receptor that binds serotonin, found higher levels of alexithymia among those ... Gong P, Liu J, Li S, Zhou X (December 2014). "Serotonin receptor gene (5-HT1A) modulates alexithymic characteristics and ...
5,N,N-TMT
The synthesis of 5-hydroxytryptamine (serotonin) and related tryptamines". Journal of the Chemical Society (Resumed): 3493-6. ... Glennon RA, Gessner PK (April 1979). "Serotonin receptor binding affinities of tryptamine analogues". Journal of Medicinal ... a correlation with serotonin receptor affinities". Psychopharmacology. 68 (2): 155-8. doi:10.1007/BF00432133. PMID 6776558. ...
7,N,N-TMT
2,N,N-TMT 5,N,N-TMT 7-Methyl-αET 7-Chloro-AMT Glennon RA, Liebowitz SM, Mack EC (August 1978). "Serotonin receptor binding ... DOBU, DOAM). 7-TMT also weakly inhibits reuptake of serotonin but with little effect on dopamine or noradrenaline reuptake. ... Glennon RA, Gessner PK (April 1979). "Serotonin receptor binding affinities of tryptamine analogues". Journal of Medicinal ... Serotonin receptor agonists, Tryptamines, Dimethylamino compounds, All stub articles, Nervous system drug stubs). ...
5-HT1B receptor
"Entrez Gene: HTR1B 5-hydroxytryptamine (serotonin) receptor 1B". "5-hydroxytryptamine (serotonin) receptor 1B, G protein- ... "Serotonin in Gut Linked to Bone Formation". Medpage Today. Archived from the original on 2016-03-03. Hoyer D, Hannon JP, Martin ... Quist JF, Barr CL, Schachar R, Roberts W, Malone M, Tannock R, Basile VS, Beitchman J, Kennedy JL (Jan 2003). "The serotonin 5- ... Tsai SJ, Wang YC, Chen JY, Hong CJ (2003). "Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A ...
Fibromyalgia
... and neurotransmitters such as serotonin. Changes in the gut biome alter serotonin levels, leading to autonomic nervous system ... Serotonin is the most widely studied neurotransmitter in fibromyalgia. It is hypothesized that an imbalance in the ... Welsch P, Üçeyler N, Klose P, Walitt B, Häuser W (February 2018). "Serotonin and noradrenaline reuptake inhibitors (SNRIs) for ... Goldenberg et al suggest that tramadol works via its serotonin and norepinephrine reuptake inhibition, rather than via its ...
Mosapride
Odaka T, Suzuki T, Seza A, Yamaguchi T, Saisho H (August 2006). "[Serotonin 5- HT4 receptor agonist (mosapride citrate)]". ... Serotonin receptor agonists, Benzamides, Morpholines, Phenol ethers, Chloroarenes, Fluoroarenes, Ethoxy compounds, Carboxamides ...
Esketamine
Rakesh G, Pae CU, Masand PS (August 2017). "Beyond serotonin: newer antidepressants in the future". Expert Review of ...
Melanin-concentrating hormone
Dopamine antagonist
Benperidol binds D2 and some serotonin receptors. It is absorbed very easily and has a high first pass effect. Chlorpromazine ... These drugs are not only dopamine antagonists at the receptor specified, but also act on serotonin receptor 5HT2A. (Citation ...
2,5-Dimethoxy-4-iodoamphetamine
In neuroscience research, [125I]-R-(−)-DOI is used as a radioligand and indicator of the presence of 5-HT2A serotonin receptors ... Yu B, Becnel J, Zerfaoui M, Rohatgi R, Boulares AH, Nichols CD (November 2008). "Serotonin 5-hydroxytryptamine(2A) receptor ... Pelletier M, Siegel RM (December 2009). "Wishing away inflammation? New links between serotonin and TNF signaling". Mol. Interv ... Yu, B; Becnel, J; Zerfaoui, M; Rohatgi, R; Boulares, AH; Nichols, CD (2008). "Serotonin 5-Hydroxytryptamine2A Receptor ...
CPCA
That is, if serotonin receptor activation is requisite for maximal efficacy, the difference SERT affinity between (-)-cis-CPCA ... These serotonin based antidepressants, in case of Paxil N-normethyl also some acetylcholinergic according to texts.[citation ... March 2011). "Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine ... March 2011). "Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine ...
Abram Hoffer
ISBN 978-0-12-374240-7. Müller, CP (2009). Jacobs B (ed.). Handbook of the Behavioral Neurobiology of Serotonin. Academic Press ...
Fluorine
ISBN 978-92-893-2562-2. Preskorn, Sheldon H. (1996). Clinical Pharmacology of Selective Serotonin Reuptake Inhibitors. Caddo: ... Many current antidepressants receive this same treatment, including the selective serotonin reuptake inhibitors: citalopram, ... had several side effects due to their non-selective interference with neurotransmitters other than the serotonin target; the ...
3,4-Dichloroamphetamine
It acts as a highly potent and selective serotonin releasing agent (SSRA) and binds to the serotonin transporter with high ... Serotonin-norepinephrine-dopamine releasing agents, Serotonin releasing agents, Substituted amphetamines, All stub articles, ... Fuller RW, Hines CW, Mills J (April 1965). "Lowering of brain serotonin level by chloramphetamines". Biochemical Pharmacology. ... "Distinct recognition of substrates by the human and Drosophila serotonin transporters". The Journal of Pharmacology and ...
Premenstrual water retention
Cochrane Gynaecology and Fertility Group) (June 2013). "Selective serotonin reuptake inhibitors for premenstrual syndrome". The ...