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*  Serotonin-norepinephrine-dopamine reuptake inhibitor
They are an extension of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors ( ... A serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), also known as a triple reuptake inhibitor (TRI), is a type of ... 2011). "SEP-225289 serotonin and dopamine transporter occupancy: A PET study". Journal of Nuclear Medicine. 52 (7): 1150-5. doi ... Another thing that is important and should be mentioned is the risk for serotonin syndrome when incorporating the element of 5- ...
*  5-HT2B receptor
Serotonin transporter: 5-HT2B receptors regulate serotonin release via the serotonin transporter, and are important both to ... Research claims serotonin 5-HT2B receptors have effect on liver regeneration. 5-HT receptor GRCh38: Ensembl release 89: ... 5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the ... Doly S, Valjent E, Setola V, Callebert J, Hervé D, Launay JM, Maroteaux L (Mar 2008). "Serotonin 5-HT2B receptors are required ...
*  Tryptophan hydroxylase
The pathway for the synthesis of serotonin from tryptophan Metabolic pathway from tryptophan to serotonin Molecular and ... The activity of tryptophan hydroxylase (i.e. the rate at which it converts L-tryptophan into the serotonin precursor L-5- ... Ichiyama A, Nakamura S, Nishizuka Y, Hayaishi O (Apr 1970). "Enzymic studies on the biosynthesis of serotonin in mammalian ... Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the neurotransmitter serotonin. Tyrosine ...
*  Reuptake inhibitor
Serotonin reuptake inhibitor Serotonin-norepinephrine reuptake inhibitor Norepinephrine-dopamine reuptake inhibitor Serotonin- ... increases inhibitor binding to the human serotonin transporter by an allosteric mechanism. Comparison with other serotonin ... Instead of binding to the active site on the serotonin transporter, they bind to an allosteric site, which exerts its effects ... A few of the selective serotonin reuptake inhibitors (SSRIs) such as the dextro-enantiomer of citalopram appear to be ...
*  5-HT receptor
The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand. The serotonin ... The 7 general serotonin receptor classes include a total of 14 known serotonin receptors. The specific types have been ... Smriga M, Torii K (2003). "L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated ... Serotonin)". Pharmacol. Rev. 46 (2): 157-203. PMID 7938165. Frazer A, Hensler JG (1999). "Chapter 13: Serotonin Receptors". In ...
*  Fenclonine
The effects of serotonin depletion from fenclonine are so drastic that serotonin cannot even be detected immunohistochemically ... It is used in scientific research in humans and animals to investigate the effects of serotonin depletion. α-Methyl-para- ... Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion ... which is a rate-limiting enzyme in the biosynthesis of serotonin. It has been used experimentally to treat carcinoid syndrome, ...
*  Serotonin syndrome
Serotonin toxicity has a rapid onset after the administration of a serotonergic drug and responds to serotonin blockade such as ... The cause of serotonin toxicity or accumulation is an important factor in determining the course of treatment. Serotonin is ... In cases of serotonin syndrome caused by monoamine oxidase inhibitors oxygenation will not help to dispatch serotonin. In such ... Some experts prefer the terms serotonin toxicity or serotonin toxidrome, to more accurately reflect that it is a form of ...
*  5-HT2C receptor agonist
5-HT receptor 5-HT2 receptor 5-HT2C receptor Serotonin receptor agonist Serotonin antagonist Serotonin Lorcaserin Vabicaserin ... Serotonin 5-HT2 receptors are stimulated by monoamine neurotransmitters including serotonin, dopamine and norepinephrine. 5-HT2 ... Dexfenfluramine inhibits serotonin reuptake, stimulating the release of serotonin. In 1996, dexfenfluramine became the first ... Later, animal studies showed that serotonin receptor agonists might act as a mediator of satiety. Serotonin has been implicated ...
*  Osemozotan
Ago, Y.; Nakamura, S.; Baba, A.; Matsuda, T. (2008). "Neuropsychotoxicity of abused drugs: effects of serotonin receptor ... 5-HT1A receptor stimulation influences the release of various neurotransmitters including serotonin, dopamine, norepinephrine, ... and is used to investigate the role of 5-HT1A receptors in modulating the release of dopamine and serotonin in the brain, and ... a serotonin 1A-receptor agonist, on methamphetamine-induced c-Fos expression in prefrontal cortical neurons". Biological & ...
*  TPH1
Walther DJ, Peter JU, Bashammakh S, Hörtnagl H, Voits M, Fink H, Bader M (January 2003). "Synthesis of serotonin by a second ... TPH1 was first discovered to synthesize serotonin in 1988 and was thought that there only was a single TPH gene until 2003, ... including serotonin, melatonin, tryptamine, N-methyltryptamine, and N,N-dimethyltryptamine. TPH1 is expressed in the body, but ... "Serotonin and melatonin synthesis in peripheral blood mononuclear cells: stimulation by interferon-gamma as part of an ...
*  Serotonin
If serotonin is released in the blood faster than the platelets can absorb it, the level of free serotonin in the blood is ... Serotonin's presence in insect venoms and plant spines serves to cause pain, which is a side-effect of serotonin injection. ... Serotonin occurs in several mushrooms of the genus Panaeolus. Serotonin is used by a variety of single-cell organisms for ... Serotonin in the brain is not usually degraded after use, but is collected by serotonergic neurons by serotonin transporters on ...
*  Serotonin (album)
Serotonin is the fourth album by Mystery Jets, released in the UK on 5 July 2010. The album is produced by Chris Thomas. " ... "Serotonin by Mystery Jets". Retrieved 19 September 2016. "BBC review". "DiS review". "Green Shoelace review". "One Thirty BPM ... "Review: Serotonin". Allmusic. Retrieved 12 July 2010. "FutureTunez review". "Pitchfork review". "Mystery Jets reveal new album ...
*  Serotonin (disambiguation)
Serotonin is a neurotransmitter. Serotonin may also refer to: Serotonin, the professional wrestling stable Serotonin (album), ... the 3rd album from British band The Mystery Jets Serotonin transporter Serotonin reuptake inhibitor. ...
*  Serotonin pathway
Serotonin is also implicated in sensory processing, as sensory stimulation causes an increase in extracellular serotonin in the ... Serotonin pathways are thought to modulate eating, both the amount as well as the motor processes associated with eating. The ... The function of serotonin in mood is more nuanced, with some evidence pointing towards increased levels leading to depression, ... Serotonin pathways projecting into the limbic forebrain are also involved in emotional processing, with decreased serotonergic ...
*  Desoxyfructo-serotonin
... is a leprostatic agent. Mester de Parajd L, Balakrishnan S, Saint-Andre P, Mester de Parajd M (1982). " ... "Deoxyfructo-serotonin: a new drug with anti-leprosy activity". Annales de microbiologie. 133 (3): 427-432. ...
*  Serotonin transporter
The Serotonin Transporter first binds a sodium ion, followed by the Serotonin, and then a chloride ion, thus it is allowed, ... This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner ... The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 ... The serotonin transporter removes serotonin from the synaptic cleft back into the synaptic boutons. Thus, it terminates the ...
*  Arachidonoyl serotonin
... (N-arachidonoyl-serotonin, AA-5-HT) is an endogenous lipid signaling molecule. It was first described in ... "Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid ...
*  Serotonin releasing agent
A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft. A ... They act as serotonin-norepinephrine-dopamine releasing agents (SNDRAs) and also agonize serotonin receptors such as those in ... Many tryptamines, such as DMT, DET, DPT, DiPT, psilocin, and bufotenin, are SRAs as well as non-selective serotonin receptor ... αET and αMT, also tryptamines, are SNDRAs and non-selective serotonin receptor agonists that were originally thought to be ...
*  Serotonin receptor agonist
A serotonin receptor agonist is an agonist of one or more serotonin receptors. They activate serotonin receptors in a manner ... Activation of the 5-HT2A receptor is also implicated in serotonin syndrome caused by indirect serotonin receptor agonists like ... Drugs that increase extracellular serotonin levels such as serotonin reuptake inhibitors (e.g., fluoxetine, venlafaxine), ... In contrast, for reasons that are unknown, LSD, which is an agonist of both the 5-HT2A receptor and many other serotonin ...
*  Serotonin receptor antagonist
A serotonin antagonist, or serotonin receptor antagonist, is a drug used to inhibit the action at serotonin (5-HT) receptors. ... Reserpine Depletes serotonin stores in the brain, heart, and many other organs and has been used in hypertension and psychosis ... Serotonin Antagonists at the US National Library of Medicine Medical Subject Headings (MeSH) MeSH list of agents 82012702. ... Please note, that although some non-selective serotonin antagonists may have an particular affinity for a specific 5-HT ...
*  Serotonin reuptake inhibitor
A serotonin reuptake inhibitor (SRI) is a type of drug which acts as a reuptake inhibitor of the neurotransmitter serotonin (5- ... A closely related type of drug is a serotonin releasing agent (SRA), an example of which is fenfluramine. Many SRIs exist, an ... Li C, Shan L, Li X, Wei L, Li D (2014). "Mifepristone modulates serotonin transporter function". Neural Regen Res. 9 (6): 646- ... SRIs are not synonymous with selective serotonin reuptake inhibitors (SSRIs), as the latter term is usually used to describe ...
*  Selective serotonin reuptake inhibitor
Serotonin syndrome is typically caused by the use of two or more serotonergic drugs, including SSRIs. Serotonin syndrome is a ... Serotonin levels within the synapse drop, then rise again, ultimately leading to downregulation of post-synaptic serotonin ... SSRIs inhibit the reuptake of serotonin. As a result, the serotonin stays in the synaptic gap longer than it normally would, ... The most commonly reported severe effect following SSRI overdose is serotonin syndrome; serotonin toxicity is usually ...
*  Serotonin-dopamine releasing agent
A serotonin-dopamine releasing agent (SDRA) is a type of drug which induces the release of serotonin and dopamine in the body ... Monoamine releasing agent Serotonin releasing agent Dopamine releasing agent Serotonin-norepinephrine-dopamine releasing agent ... UWA-101 is an SDRI that, based on its chemical structure, may also have efficacy as a releasing agent of serotonin and dopamine ... A closely related type of drug is a serotonin-dopamine reuptake inhibitor (SDRI). A number of tryptamine derivatives have been ...
*  Serotonin-norepinephrine reuptake inhibitor
Selective serotonin reuptake inhibitors (SSRIs) selectively inhibit the reuptake of serotonin and are a widely used group of ... Agents with dual serotonin and norepinephrine reuptake inhibition (SNRIs) are sometimes called non-tricyclic serotonin and ... SSNRIs can be contrasted with the more widely used selective serotonin reuptake inhibitors (SSRIs), which act upon serotonin ... Serotonin is synthesized from an amino acid called L-tryptophan. Active transport system regulates the uptake of tryptophan ...
*  Allosteric serotonin reuptake inhibitor
... is a type of selective serotonin reuptake inhibitor (SSRI). Currently only escitalopram ... non-overlapping binding sites for the two different isomers on the serotonin transporter. Escitalopram, thus, binds not only to ...