Loading...
*  Atrial natriuretic peptide
Neutral endopeptidase (NEP) also known as neprilysin is the enzyme that metabolizes natriuretic peptides. Several inhibitors of ... c) All rights reserved Yan W, Sheng N, Seto M, Morser J, Wu Q (May 1999). "Corin, a mosaic transmembrane serine protease ... Yan W, Wu F, Morser J, Wu Q (Jul 2000). "Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic ... As a consequence, cGMP activates a cGMP-dependent kinase (PKG or cGK) that phosphorylates proteins at specific serine and ...
*  IgA specific serine endopeptidase
IgA-specific serine endopeptidase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular ... IgA protease (EC 3.4.21.72, IgA-specific serine endopeptidase, IgA proteinase, IgA-specific proteinase, immunoglobulin A ... where the X in the squence preferably is a Proline or Serine; the Y = Threonine, Serine or Alanine; and Z preferably is ...
*  Exosite
Serine Endopeptidases: Advances in Research and Application: 2011 Edition. ScholarlyAdditions. Retrieved 11 May 2013. http:// ...
*  Implantation (human embryo)
The extracellular matrix is degraded by serine endopeptidases and metalloproteinases. Examples of such metalloproteinases are ...
*  Factor X
It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and requires vitamin K for its ... Factor X is an enzyme, a serine endopeptidase, which plays a key role at several stages of the coagulation system. Factor X is ... Factor Xa is inactivated by protein Z-dependent protease inhibitor (ZPI), a serine protease inhibitor (serpin). The affinity of ... "Complementary DNA cloning and kinetic characterization of a novel intracellular serine proteinase inhibitor: mechanism of ...
*  Factor XII
It is the zymogen form of factor XIIa, an enzyme (EC 3.4.21.38) of the serine protease (or serine endopeptidase) class. In ... Chung DW, Fujikawa K, McMullen BA, Davie EW (May 1986). "Human plasma prekallikrein, a zymogen to a serine protease that ...
*  Pancreatic elastase
... 1 is a serine endopeptidase, a specific type of protease that has the amino acid serine at its active site ... Studies of human pancreatic elastase 1 have shown that this serine protease maps to the chromosomal region 12q13 and it is ... Elastases form a subfamily of serine proteases, characterized by a distinctive structure consisting of two beta barrel domains ... or serine elastase. The first isozyme, pancreatic elastase 1, was initially thought to be expressed in the pancreas. However it ...
*  Serine protease
... s (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins, in which serine serves as the ... Serine Peptidase Serine Proteases site at Saint Louis University (SLU) Serine proteases at the US National Library of Medicine ... The serine -OH attacks the carbonyl carbon, and the nitrogen of the histidine accepts the hydrogen from the -OH of the [serine ... Serine proteases are paired with serine protease inhibitors, which turn off their activity when they are no longer needed. ...
*  List of MeSH codes (D08)
... serine endopeptidases MeSH D08.811.277.656.300.760.030 --- acrosin MeSH D08.811.277.656.300.760.176 --- chymotrypsin MeSH ... endopeptidase clp MeSH D08.811.277.656.149.500 --- protease la MeSH D08.811.277.656.300 --- endopeptidases MeSH D08.811.277.656 ... endopeptidase clp MeSH D08.811.277.656.300.760.247 --- endopeptidase k MeSH D08.811.277.656.300.760.284 --- enteropeptidase ... Serine-type D-Ala-D-Ala carboxypeptidase MeSH D08.811.277.656.350.245.280 --- gamma-glutamyl hydrolase MeSH D08.811.277.656. ...
*  Peptidase Do
... such as Val-Val This Escherichia coli serine endopeptidase is essential for the clearance of denatured proteins from the inner- ... Pallen, M.J.; Wren, B.W. (1997). "The HtrA family of serine proteases". Mol. Microbiol. 26 (2): 209-221. doi:10.1046/j.1365- ... is an endopeptidase". J. Bacteriol. 172 (4): 1791-1797. doi:10.1128/jb.172.4.1791-1797.1990. PMC 208670 . PMID 2180903. Seol, J ... a large serine protease containing multiple subunits". Arch. Biochem. Biophys. 224 (2): 543-554. doi:10.1016/0003-9861(83)90242 ...
*  Subtilisin
... serine endopeptidase). The structure of subtilisin has been determined by X-ray crystallography. It is a 275-residue globular ... Subtilisins belong to subtilases, a group of serine proteases that - like all serine proteases - initiate the nucleophilic ... It is structurally unrelated to the chymotrypsin-clan of serine proteases, but uses the same type of catalytic triad in the ... Polgár L (1987). "Structure and function of serine proteases". In Brocklehurst K; Neuberger A. Hydrolytic enzymes. Amsterdam: ...
*  List of EC numbers (EC 3)
Pancreatic endopeptidase E EC 3.4.21.71: Pancreatic elastase II EC 3.4.21.72: IgA-specific serine endopeptidase EC 3.4.21.73: u ... Ste24 endopeptidase EC 3.4.24.85: S2P endopeptidase EC 3.4.24.86: ADAM 17 endopeptidase EC 3.4.24.87: ADAMTS13 endopeptidase EC ... ADAM10 endopeptidase EC 3.4.24.82: ADAMTS-4 endopeptidase EC 3.4.24.83: anthrax lethal factor endopeptidase EC 3.4.24.84: ... Now considered EC 3.4.21.25, cucumisin EC 3.4.21.57: Leucyl endopeptidase EC 3.4.21.58: Deleted entry: prohormone serine ...
*  Glutamyl endopeptidase I
S. epidermidis glutamyl endopeptidase GluSE Also called S. epidermidis serine protease (Esp). S. warneri glutamyl endopeptidase ... subtilis glutamyl endopeptidase GluBS Enterococcus E. faecalis glutamyl endopeptidase SprE Glutamyl endopeptidase is in at ... Glutamyl endopeptidase I is a family of extracellular bacterial serine proteases. The proteases within this family have been ... purification and characterization of isoforms of an extracellular serine glutamyl endopeptidase of Enterococcus faecalis with ...
*  Kexin
"Yeast KEX2 gene encodes an endopeptidase homologous to subtilisin-like serine proteases". Biochem. Biophys. Res. Commun. 156: ... paired-basic endopeptidase, yeast cysteine proteinase F, paired-basic endopeptidase, andrenorphin-Gly-generating enzyme, ... Fuller RS, Brake A, Thorner J (1989). "Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine ... Mizuno K, Nakamura T, Ohshima T, Tanaka S, Matsuo H (1989). "Characterization of KEX2-encoded endopeptidase from yeast ...
*  Aureolysin
... it proteolytically activates the zymogen of the serine protease glutamyl endopeptidase, which in turn is the activator of ... An immunization survey of human serum samples suggests that exposure to S. aureus glutamyl endopeptidase is common, although a ... and serine protease (sspA) transcription in Staphylococcus aureus by sarA, rot and agr (RNAIII)". International journal of ... "Activation of the SspA serine protease zymogen of Staphylococcus aureus proceeds through unique variations of a trypsinogen- ...
*  Leucyl endopeptidase
... (EC 3.4.21.57, plant Leu-proteinase, leucine-specific serine proteinase, leucine endopeptidase, spinach ... CS1 maint: Multiple names: authors list (link) Leucyl endopeptidase at the US National Library of Medicine Medical Subject ... serine proteinase (leucine specific), spinach leucine-specific serine proteinase, Leu-proteinase) is an enzyme. This enzyme ... the leucine specific serine proteinase from spinach (Spinacia oleracea L.) leaves". Plant Physiol. 81: 812-816. doi:10.1104/pp. ...
*  Angiostatin
13 KD serine protease, or 24KD endopeptidase. Angiostatin is known to bind many proteins, especially to angiomotin and ...
*  Glutamyl endopeptidase GluV8
... staphylococcal serine proteinase) is an extracellular bacterial serine protease of the glutamyl endopeptidase I family that was ... Glutamyl endopeptidase is in S. aureus expressed from the gene sspA within the operon ssp. Downstream of sspA, the operon also ... Glutamyl endopeptidase is expressed as a zymogen that, in order to become fully active, has been modified both through ... Glutamyl endopeptidase can inhibit the activation of targets within the complement system. It is indicated to cause inhibition ...
*  Prolyl endopeptidase
... is a large cytosolic enzyme that belongs to a distinct class of serine peptidases. It was first described ... Prolyl endopeptidase is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues ... prolyl endopeptidase, human at the US National Library of Medicine Medical Subject Headings (MeSH) Prolyl Endopeptidase entry ... "Entrez Gene: PREP prolyl endopeptidase". Oliveira EB, Martins AR, Camargo AC (May 1976). "Isolation of brain endopeptidases: ...
*  Endopeptidase So
... (EC 3.4.21.67, E. coli cytoplasmic proteinase, proteinase So, Escherichia coli serine proteinase So) is an ... Endopeptidase So at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology portal. ... Chung, C.H.; Goldberg, A.L. (1983). "Purification and characterization of protease So, a cytoplasmic serine protease in ... or Bz-Arg-OEt This is an Escherichia coli cytoplasmic endopeptidase. Goldberg, A.L.; Swamy, K.H.S.; Chung, C.H.; Larimore, F.S ...
*  Cathepsin C
... exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases". The EMBO ... Cathepsin C functions as a key enzyme in the activation of granule serine peptidases in inflammatory cells, such as elastase ... Cathepsin C appears to be a central coordinator for activation of many serine proteases in immune/inflammatory cells. Cathepsin ...
*  Lysyl endopeptidase
... a lysine-specific serine protease". J. Biol. Chem. 264: 3832-3839. PMID 2492988. Lysyl endopeptidase at the US National Library ... Lysyl endopeptidase (EC 3.4.21.50, Achromobacter proteinase I, Achromobacter lyticus alkaline proteinase I, protease I, ... of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology portal Lysyl Endopeptidase is the registered ...
*  Clp protease family
Endopeptidase Clp ATP-dependent Clp protease proteolytic subunit Maurizi MR, Clark WP, Katayama Y, Rudikoff S, Pumphrey J, ... In molecular biology, the CLP protease family is a family of serine peptidases belong to the MEROPS peptidase family S14 (ClpP ... endopeptidase family, clan SK). ClpP is an ATP-dependent protease that cleaves a number of proteins, such as casein and albumin ...
*  Proteinase K
Tritirachium album serine proteinase, Tritirachium album proteinase K) is a broad-spectrum serine protease. The enzyme was ... In molecular biology Proteinase K (EC 3.4.21.64, protease K, endopeptidase K, Tritirachium alkaline proteinase, ... Temperatures above 65 °C, trichloroacetic acid (TCA) or the serine protease-inhibitors AEBSF, PMSF or DFP inhibit the activity ... EDTA or by other serine protease inhibitors like Nα-Tosyl-Lys Chloromethyl Ketone (TLCK) and Nα-Tosyl-Phe Chloromethyl Ketone ( ...
*  Endopeptidase La
... (EC 3.4.21.53, ATP-dependent serine proteinase, lon proteinase, protease La, proteinase La, ATP-dependent lon ... Endopeptidase La at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology portal. ... serine protease La) is an enzyme. This enzyme catalyses the following chemical reaction Hydrolysis of proteins in presence of ... proteinase, ATP-dependent protease La, Escherichia coli proteinase La, Escherichia coli serine proteinase La, gene lon protease ...
*  Alpha-lytic endopeptidase
This enzyme is a serine protease that catalyses the breakage of peptide bonds using a hydrolysis chemical reaction. Alpha-lytic ... Alpha-lytic endopeptidase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology ... Alpha-lytic endopeptidase or Alpha-lytic protease (EC 3.4.21.12, myxobacter alpha-lytic proteinase, alpha-lytic proteinase, ... Polgar, L. (1987). "Structure and function of serine proteases". In Neuberger, A.; Brocklehurst, K. New Comprehensive ...
*  Endopeptidase inhibitor
... serine, and threonine proteases Nafamostat - inhibitor of trypsin, tryptase, and various other serine proteases Pacifastins - ... An endopeptidase inhibitor is a drug that inhibits one or more endopeptidase enzymes. Endopeptidases are one of two types of ... Endopeptidases cleave peptide bonds of non-terminal amino acids (that is, they cut proteins/peptides into two chains), whereas ... Some examples of endopeptidase inhibitors include the following: Neprilysin inhibitors Selective neprilysin inhibitors ...