They display significant amino acid sequence homology. Sixteen cysteine residues, forming 8 disulfide bonds, are strictly ... Piscivorin has the following amino acid sequence. Piscivorin reduces high potassium-evoked smooth muscle contraction, but does ... A sequence comparison of piscivorin and other CRISP family proteins suggests that the Glu186 residue is the crucial site for ... The nucleotide sequence of piscivorin cDNA spans 1323 bp, containing an open reading frame of 240 codons. ...
Marcus F, Gontero B, Harrsch PB, Rittenhouse J (Mar 1986). "Amino acid sequence homology among fructose-1,6-bisphosphatases". ... Fructose bisphosphatase deficiency Fructose Gluconeogenesis Metabolism Marcus F, Harrsch PB (May 1990). "Amino acid sequence of ... IMPase and FBPase share a sequence motif (Asp-Pro-Ile/Leu-Asp-Gly/Ser-Thr/Ser) which has been shown to bind metal ions and ... do not show any significant sequence similarity to the enzymes from other organisms. The Bacillus subtilis enzyme is inhibited ...
This is not to be confused with conservation in amino acid sequences, where the amino acid at a specific position has been ... Homology among DNA, RNA, or proteins is typically inferred from their nucleotide or amino acid sequence similarity. Significant ... A sequence alignment of mammalian histone proteins. Sequences are the middle 120-180 amino acid residues of the proteins. ... Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the ...
It was subsequently cloned and sequenced by Radhey Gupta and coworkers. The amino acid sequence showed a strong homology to ... The cytoplasmic HSP60 contains a signal sequence of 26 amino acids on the N terminus. This sequence is highly degenerate and is ... With respect to the amino acid sequence, the cytoplasmic HSP60 has an N-terminal sequence not found in the mitochondrial ... Moreover, HSP60's amino acid sequence bears a similarity to its homolog in plants, bacteria, and humans. Heat shock proteins ...
Amino acid sequence of MTA2 shares 68.2% homology with MTA1's sequence. MTA2 domains include, a BAH (Bromo-Adjacent Homology), ... inclusive of three protein-coding transcripts but predicted to code for two polypeptides of 688 amino acids and 495 amino acids ... The murine Mta2 consists of a 3.1-kb protein-coding transcript to code a protein of 668 amino acids, and five non-coding RNAs ... MTA2 was initially recognized as an MTA1 like 1 gene, named MTA1-L1, from a large scale sequencing of randomly selected clones ...
... they share gene sequence and amino acid sequence homology. They all also possess conserved amino acids that are important for ... those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before ... The CC chemokine (or β-chemokine) proteins have two adjacent cysteines (amino acids), near their amino terminus. There have ... A loop of approximately ten amino acids follows the first two cysteines and is known as the N-loop. This is followed by a ...
... coding for 2,710 amino acids. TcdA and TcdB share 63% homology in their amino acid sequences. These genes are expressed during ... A centrally located hydrophobic domain containing a cluster of 172 highly conserved hydrophobic amino acids is thought to be ... which transfers a glucose molecule from UDP-Glucose and covalently attaches it to conserved amino acids in target molecules. ... Due to its homology with other proteins of similar function, as well as the location of the gene between tcdA and tcdB, tcdE is ...
Over 200 subtilases are presently known, more than 170 of which with their complete amino acid sequence. Subtilase is ... Based on sequence homology, a subdivision into six families has been proposed. The proprotein-processing endopeptidases kexin, ... These preferentially cleave C-terminally to paired basic amino acids. Members of this subfamily can be identified by subtly ... with the mature catalytic domains containing approximately 375 amino acids. The defining features of these enzymes are a unique ...
Kleeman TA, Wei D, Simpson KL, First EA (Jun 1997). "Human tyrosyl-tRNA synthetase shares amino acid sequence homology with a ... by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, ... 2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40-5. doi:10.1038/ ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
There is a high homology in the amino acid sequence within each family. Each family couples to the same second messenger ...
... is a 36-amino acid peptide found in the venom of the deathstalker scorpion (Leiurus quinquestriatus) which blocks ... Chlorotoxin has a considerable sequence homology to the class of small insectotoxins. Chlorotoxin is the first reported high- ... It is a peptide consisting of 36 amino acids, with 8 cysteines forming 4 disulfide bonds. ...
Lottspeich F, Geiger R, Henschen A, Kutzbach C (1980). "N-Terminal amino acid sequence of human urinary kallikrein homology ... Complete amino acid sequence and sites of glycosylation". Int. J. Pept. Protein Res. 33 (4): 237-49. doi:10.1111/j.1399- ... 1986). "N-terminal amino acid sequence of human urinary prokallikrein". J. Biochem. 99 (3): 989-92. PMID 3635530. Baker AR, ... Kellermann J, Lottspeich F, Geiger R, Deutzmann R (1988). "Human urinary kallikrein--amino acid sequence and carbohydrate ...
They share 57% amino acid sequence homology and have some pharmacological characteristics in common. Both receptors are Gi- ... indicating a high degree of evolutionary conservation of genetic sequence, which suggests that the 5-HT1E receptor has an ...
The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J Biol Chem. 1978, ... Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature. 1983, 306 (5943): 609-11. PMID 6358902. doi: ...
... according to sequence homology. The synthetases specific for alanine, asparagine, aspartic acid, glycine, histidine, lysine, ... The aminoacyl-tRNA synthetases (EC 6.1.1.) catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a ... These proteins differ widely in size and oligomeric state, and have limited sequence homology. The 20 aminoacyl-tRNA ... Cusack S, Leberman R, Hartlein M (1991). "Sequence, structural and evolutionary relationships between class 2 aminoacyl-tRNA ...
Some of the proteins participating in T3SS share amino-acid sequence homology to flagellar proteins. Some of the bacteria ... Recognition is done through a secretion signal-a short sequence of amino acids located at the beginning (the N-terminus) of the ... This is done in order to define the function of specific amino acids or regions in a protein. The introduction of a gene or a ... usually within the first 20 amino acids), that the needle complex is able to recognize. Unlike other secretion systems, the ...
... have high homology. They have 65% amino acid sequences in common and 92% homology within their kinase domains. ROCKs are ... Mammalian ROCK consists of a kinase domain, a coiled-coil region and a Pleckstrin homology (PH) domain, which reduces the ... ROCK can also be regulated by lipids, in particular arachidonic acid, and protein oligomerization, which induces N-terminal ...
Huhtala ML, Seppälä M, Närvänen A, Palomäki P, Julkunen M, Bohn H (Jun 1987). "Amino acid sequence homology between human ... Julkunen M, Seppälä M, Jänne OA (Dec 1988). "Complete amino acid sequence of human placental protein 14: a progesterone- ... This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have ... Vaisse C, Atger M, Potier B, Milgrom E (1990). "Human placental protein 14 gene: sequence and characterization of a short ...
... complete amino acid sequence and homologies". Science. 230 (4732): 1385-8. Bibcode:1985Sci...230.1385G. doi:10.1126/science. ... A short stretch of acidic amino acids located between the D1 and D2 domains has auto-inhibitory functions. This 'acid box' ... Although these factors possess remarkably similar sequence homology, they do not bind FGFRs and are involved in intracellular ... These proteins had a high degree of amino acid identity but were determined to be distinct mitogens. Human FGF2 occurs in low ...
... and at 786 amino acids is the longest one.[10] Amino acid sequence homology of this isoform of human CASS4 with other family ... but lacks obvious similarity at the level of primary amino acid sequence. It also lacks a YDYVHL sequence at the N-terminal end ... 786 amino acids, considered the major isoform), the third one contains 6 exons and encodes a shorter isoform b (732 amino acids ... 349 amino acids). Cumulatively, the CASS4 transcripts are most highly expressed in spleen and lung among normal tissues, and ...
H9401 has 99.679% sequence homology with Ames Ancestor with an amino acid sequence homology of 99.870%. H9401 has a circular ... These include 1) N-glycosylation of N-acetyl-muramic acid, 2) O-acetylation of N-acetylmuramic acid and 3) N-deacetylation of N ... The sequencing coverage level suggests a molecular ratio of pXO1:pXO2:chromosome as 3:2:1 which is identical to the Ames ... Due to the high pathogenecity and sequence similarity to the Ames Ancestor, H9401 will be used as a reference for testing the ...
"Nucleotide and amino acid sequences of human intestinal alkaline phosphatase: close homology to placental alkaline phosphatase ... 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ... "Cloning and sequencing of human intestinal alkaline phosphatase cDNA". Proc. Natl. Acad. Sci. U.S.A. 84 (3): 695-8. doi:10.1073 ...
The complete amino acid sequence has been defined and it displays 68% sequence homology with charybdotoxin. Iberiotoxin binds ... Iberiotoxin is a 37-amino acid peptide. The formula is C179H274N50O55S7. It is also known as "Potassium channel toxin alpha-KTx ...
... homologies and mechanistic implications of deduced amino acid sequences". Cell. 44 (4): 597-607. doi:10.1016/0092-8674(86)90269 ... 2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci ...
The order of these seven LSm proteins in this ring is not known, but based on amino acid sequence homology with the Sm proteins ... Each of the seven Sm proteins has greater amino acid sequence homology to a corresponding Lsm protein than to the other Sm ... such as multiple sequence alignment of the primary structure (amino acid sequence), and structural alignment of the tertiary ... comparisons between the various LSm homologs identified two sequence motifs, 32 nucleic acids long (14 amino acids), that were ...
They each share about 25% amino acid sequence identity with RAD51 and with each other.[28] ... RAD51 is involved in the search for homology and strand pairing stages of the process. ... In humans, RAD51 is a 339-amino acid protein that plays a major role in homologous recombination of DNA during double strand ... "Nucleic Acids Research. 25 (19): 3868-74. doi:10.1093/nar/25.19.3868. PMC 146972 . PMID 9380510.. ...