Semialdehyde
In organic chemistry, a semialdehyde is a compound containing an aldehyde and a carboxylic acid functional groups. ...
Succinic semialdehyde
When the oxidation of succinic semialdehyde to succinic acid is impaired, accumulation of succinic semialdehyde takes place ... Succinic semialdehyde (SSA) is a GABA metabolite. It is formed from GABA by the action of GABA transaminase (4-aminobutyrate ... SSA is oxidized into succinic acid by the enzyme succinic semialdehyde dehydrogenase, which uses NAD+ as a cofactor. ... Transaminase (aminotransferase) Succinic semialdehyde dehydrogenase deficiency Lide, David R. (1998), Handbook of Chemistry and ...
Aspartate-semialdehyde dehydrogenase
BLACK S, WRIGHT NG (1955). "Aspartic beta-semialdehyde dehydrogenase and aspartic beta-semialdehyde". J. Biol. Chem. 213 (1): ... L-aspartate-beta-semialdehyde:NADP+ oxidoreductase, (phosphorylating), aspartic beta-semialdehyde dehydrogenase, and ASA ... Aspartate-semialdehyde dehydrogenase may be cis-regulated by an Asd RNA motif found in the 5' UTR of some Asd genes. This ... Other names in common use include aspartate semialdehyde dehydrogenase, aspartic semialdehyde dehydrogenase, ...
Glutamate-1-semialdehyde
... is a molecule formed from by the reduction of tRNA bound glutamate, catalyzed by glutamyl-tRNA ... Glutamate-5-semialdehyde Beale SI (August 1990). "Biosynthesis of the Tetrapyrrole Pigment Precursor, delta-Aminolevulinic Acid ... It is isomerized by glutamate-1-semialdehyde 2,1-aminomutase to give aminolevulinic acid in the biosynthesis of porphyrins, ...
Glutamate-5-semialdehyde
Reduction of glutamic acid semialdehyde with sodium borohydride gives hydroxyaminovaleric acid. Glutamate-1-semialdehyde Baich ... Glutamate-5-semialdehyde is a non-proteinogenic amino acid involved in both the biosynthesis and degradation of proline and ... It is synthesized by the reduction of glutamyl-5-phosphate by glutamate-5-semialdehyde dehydrogenase. ... A (1971). "The Biosynthesis of Proline in Escherichia coli: Phosphate-Dependent Glutamate-semialdehyde Dehydrogenase (NADP), ...
2-Hydroxymuconate semialdehyde
... is formed from catechol by the enzyme catechol 2,3-dioxygenase during the degradation of ... It is hydrolysed into formate and 2-oxopent-4-enoate by 2-hydroxymuconate-semialdehyde hydrolase. Sala-Trepat JM, Evans WC ( ...
Aminoadipate-semialdehyde dehydrogenase
"Entrez Gene: Aminoadipate-semialdehyde dehydrogenase". Retrieved 2017-01-02. Wang L, Jil C, Xu Y, Xu J, Dai J, Wu Q, Wu M, Zou ... Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene. This gene encodes a member of ...
Malonate-semialdehyde dehydrogenase
In enzymology, a malonate-semialdehyde dehydrogenase (EC 1.2.1.15) is an enzyme that catalyzes the chemical reaction 3- ... Nakamura K, Bernheim F (June 1961). "Studies on malonic semialdehyde dehydrogenase from Pseudomonas aeruginosa". Biochimica et ...
2-Aminomuconic semialdehyde
... is a metabolite of tryptophan. Muconic acid Ommochrome He, Z.; Spain, J. (1999-08-01). "Preparation ...
Aminocarboxymuconate-semialdehyde decarboxylase
The enzyme aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) catalyzes the chemical reaction 2-amino-3-(3-oxoprop-1 ... 2-aminomuconate-semialdehyde-forming). Other names in common use include picolinic acid carboxylase, picolinic acid ... alpha-amino-beta-carboxymuconate-epsilon-semialdehyde, beta-decarboxylase, 2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy- ... 1-yl)but-2-enedioate ⇌ {\displaystyle \rightleftharpoons } 2-aminomuconate semialdehyde + CO2 This enzyme belongs to the family ...
Succinate-semialdehyde dehydrogenase
... succinic semialdehyde dehydrogenase, succinyl semialdehyde dehydrogenase, and succinate semialdehyde:NAD+ oxidoreductase. This ... Succinate-semialdehyde dehydrogenase is found in organisms ranging across the tree of life from bacteria to humans. It is ... In enzymology, a succinate-semialdehyde dehydrogenase (SSADH) (EC 1.2.1.24) is an enzyme that catalyzes the chemical reaction ... The systematic name of this enzyme class is succinate-semialdehyde:NAD+ oxidoreductase. Other names in common use include ...
Succinylglutamate-semialdehyde dehydrogenase
Other names in common use include succinylglutamic semialdehyde dehydrogenase, N-succinylglutamate 5-semialdehyde dehydrogenase ... In enzymology, a succinylglutamate-semialdehyde dehydrogenase (EC 1.2.1.71) is an enzyme that catalyzes the chemical reaction N ... The systematic name of this enzyme class is N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase. ... 2 H+ The 3 substrates of this enzyme are N-succinyl-L-glutamate 5-semialdehyde, NAD+, and H2O, whereas its 3 products are N- ...
Tartronate-semialdehyde synthase
... hydroxymalonic semialdehyde carboxylase, tartronic semialdehyde carboxylase, glyoxalate carboligase, and glyoxylate carboxy- ... The enzyme tartronate-semialdehyde synthase (EC 4.1.1.47) catalyzes the chemical reaction 2 glyoxylate ⇌ {\displaystyle \ ... The systematic name of this enzyme class is glyoxylate carboxy-lyase (dimerizing tartronate-semialdehyde-forming). Other names ... rightleftharpoons } tartronate semialdehyde + CO2 This enzyme belongs to the family of lyases, specifically the carboxy-lyases ...
Aminomuconate-semialdehyde dehydrogenase
Other names in common use include 2-aminomuconate semialdehyde dehydrogenase, 2-hydroxymuconic acid semialdehyde dehydrogenase ... alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase, and 2-hydroxymuconic semialdehyde dehydrogenase. Ichiyama A, Nakamura ... 2-hydroxymuconate semialdehyde dehydrogenase, alpha-aminomuconic epsilon-semialdehyde dehydrogenase, ... In enzymology, an aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) is an enzyme that catalyzes the chemical reaction 2- ...
Methylmalonic acid semialdehyde
... is an intermediate in the metabolism of thymine and valine. Methylmalonate-semialdehyde ...
Glutarate-semialdehyde dehydrogenase
V. Glutaric semialdehyde dehydrogenase". Journal of Biochemistry. 49: 154-7. PMID 13717359. Portal: Biology v t e (EC 1.2.1, ... The systematic name of this enzyme class is glutarate-semialdehyde:NAD+ oxidoreductase. This enzyme is also called glutarate ... In enzymology, a glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) is an enzyme that catalyzes the chemical reaction glutarate ... 2 H+ The 3 substrates of this enzyme are glutarate semialdehyde, NAD+, and H2O, whereas its 3 products are glutarate, NADH, and ...
Tartronic acid semialdehyde
... is the organic compound with the formula OCHCH(OH)CO2H. The molecule has three functional groups, ... Tartronate semialdehyde is produced and consumed on a prodigious scale as an intermediate in photorespiration, an undesirable ... A near neutral pH, it exists as the hydrated carboxylate (HO)2CHCH(OH)CO2−, which is referred to as tartronate semialdehyde. ... CO2 This condensation is catalyzed by tartronate-semialdehyde synthase. Leegood RC (May 2007). "A Welcome Diversion from ...
Methylmalonate semialdehyde dehydrogenase
... may refer to: Methylmalonate-semialdehyde dehydrogenase (acylating) ALDH6A1 This ... disambiguation page lists articles associated with the title Methylmalonate semialdehyde dehydrogenase. If an internal link led ...
Alpha-aminoadipic semialdehyde synthase
... is an enzyme encoded by the AASS gene in humans and is involved in their major lysine ... Alpha-aminoadipic semialdehyde synthase is encoded for by the AASS gene, and mutations in this gene lead to hyperlysinemia. ... The alpha-aminoadipic semialdehyde synthase protein catalyzes the first two steps in the mammalian L-lysine degradation via ... "Alpha-aminoadipic semialdehyde synthase, mitochondrial". UniProt. Retrieved 2017-03-04. Houten SM, Te Brinke H, Denis S, Ruiter ...
Methylmalonate-semialdehyde dehydrogenase (acylating)
In enzymology, a methylmalonate-semialdehyde dehydrogenase (acylating) (EC 1.2.1.27) is an enzyme that catalyzes the chemical ... Sokatch JR, Sanders LE, Marshall VP (1968). "Oxidation of methylmalonate semialdehyde to propionyl coenzyme A in Pseudomonas ... Stines-Chaumeil C, Talfournier F, Branlant G (2006). "Mechanistic characterization of the MSDH (methylmalonate semialdehyde ... crystallization and preliminary X-ray diffraction data of methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis" ( ...
2-hydroxymuconate-semialdehyde hydrolase
In enzymology, a 2-hydroxymuconate-semialdehyde hydrolase (EC 3.7.1.9) is an enzyme that catalyzes the chemical reaction 2- ... The systematic name of this enzyme class is 2-hydroxymuconate-semialdehyde formylhydrolase. Other names in common use include 2 ... the two substrates of this enzyme are 2-hydroxymuconate semialdehyde and H2O, whereas its two products are formate and 2- ... hydroxymuconate semialdehyde + H2O ⇌ {\displaystyle \rightleftharpoons } formate + 2-oxopent-4-enoate Thus, ...
L-aminoadipate-semialdehyde dehydrogenase
Other names in common use include: aminoadipate semialdehyde dehydrogenase, 2-aminoadipate semialdehyde dehydrogenase, alpha- ... 2-aminoadipic semialdehyde dehydrogenase, L-alpha-aminoadipate delta-semialdehyde oxidoreductase, L-alpha-aminoadipate delta- ... semialdehyde:NAD+ oxidoreductase, L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine, and dinucleotide oxidoreductase ... In enzymology, a L-aminoadipate-semialdehyde dehydrogenase (EC 1.2.1.31) is an enzyme that catalyzes the chemical reaction L-2- ...
Succinic semialdehyde dehydrogenase deficiency
The succinic semialdehyde can be converted into either succinic acid by SSADH or to GHB by the enzyme succinic semialdehyde ... Succinate semialdehyde is considered a reactive carbonyl and may lead to increased oxidative stress. This stress is believed to ... Finally, succinic semialdehyde dehydrogenase levels can be measured in cultured leukocytes of the patient. This occurs due to ... Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare autosomal recessive disorder of the degradation pathway of ...
Succinate-semialdehyde dehydrogenase (acylating)
... coenzyme-A-dependent succinate-semialdehyde dehydrogenase) is an enzyme with systematic name succinate semialdehyde:NADP+ ... Succinate-semialdehyde+dehydrogenase+(acylating) at the U.S. National Library of Medicine Medical Subject Headings (MeSH) ... Söhling B, Gottschalk G (February 1993). "Purification and characterization of a coenzyme-A-dependent succinate-semialdehyde ... Succinate-semialdehyde dehydrogenase (acylating) (EC 1.2.1.76, succinyl-coA reductase, ...
Malonate-semialdehyde dehydrogenase (acetylating)
V. Direct conversion of malonic semialdehyde to acetyl-coenzyme A". The Journal of Biological Chemistry. 235: 589-94. PMID ... In enzymology, a malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) is an enzyme that catalyzes the chemical ... This enzyme is also called malonic semialdehyde oxidative decarboxylase. This enzyme participates in 4 metabolic pathways: ...
L-Aspartic-4-semialdehyde
... (also L-aspartate-4-semialdehyde) is an α-amino acid derivative of aspartate. It is an important ... L-Aspartate-4-semialdehyde is synthesized by the enzyme aspartate semialdehyde dehydrogenase, which catalyzes the following ... This reaction, which turns L-aspartate-4-semialdehyde into homoserine is shown below: L-Aspartate-4-semialdehyde + NAD(P)H + H+ ... L-aspartate-4-semialdehyde + NADP+ + phosphate Once L-aspartate-4-semialdehyde is synthesized, the molecule can then progress ...
Succinate-semialdehyde dehydrogenase (NADP+)
... (EC 1.2.1.79, succinic semialdehyde dehydrogenase (NADP+), succinyl semialdehyde ... NADP-dependent succinate-semialdehyde dehydrogenase, GabD) is an enzyme with systematic name succinate-semialdehyde:NADP+ ... succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD)". ... Succinate-semialdehyde+dehydrogenase+(NADP+) at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Portal: ...
4-hydroxymuconic-semialdehyde dehydrogenase
In enzymology, a 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) is an enzyme that catalyzes the chemical reaction 4- ... The systematic name of this enzyme class is 4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase. This enzyme participates in ... 2 H+ The 3 substrates of this enzyme are 4-hydroxymuconic semialdehyde, NAD+, and H2O, whereas its 3 products are maleylacetate ... hydroxymuconic semialdehyde + NAD+ + H2O ⇌ {\displaystyle \rightleftharpoons } maleylacetate + NADH + ...
Glutamate-5-semialdehyde dehydrogenase
... glutamate semialdehyde dehydrogenase, and glutamate-gamma-semialdehyde dehydrogenase. This enzyme participates in urea cycle ... In enzymology, a glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) is an enzyme that catalyzes the chemical reaction L- ... The systematic name of this enzyme class is L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating). Other names in ... Baich A (July 1971). "The biosynthesis of proline in Escherichia coli: phosphate-dependent glutamate -semialdehyde ...
2-Amino-3-carboxymuconic semialdehyde
... is enzymatically converted to 2-aminomuconate via 2-aminomuconic semialdehyde. "UniProt ... 2-Amino-3-carboxymuconic semialdehyde is an intermediate in the metabolism of tryptophan in the tryptophan-niacin catabolic ... "Human Metabolome Database: Showing metabocard for 2-Amino-3-carboxymuconic acid semialdehyde (HMDB0001330)". hmdb.ca. Retrieved ... Quinolinate is a neurotoxin formed nonenzymatically from 2-amino-3-carboxymuconic semialdehyde in mammalian tissues. ...