... is a class A scavenger receptor that is found on particular subsets of macrophages. Scavenger receptors are pattern ... Other members of the class A scavenger receptors tend to have alpha helical coiled coil domains, but MARCO does not. The C- ... Bowdish DM, Gordon S (January 2009). "Conserved domains of the class A scavenger receptors: evolution and function". ... February 1995). "Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a ...
CD36 and scavenger receptor class BI are identified as genes encoding for oxidized LDL receptors and classified into scavenger ... A Drosophila class C scavenger receptor (dSR-C1) also has a mucin-like structure. Lectin-like oxidized LDL receptor-1 (LOX-1) ... Scavenger+receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human scavenger-like receptors in ... receptor scavenger receptor class B type I reveals its key role in HDL metabolism". Proceedings of the National Academy of ...
"Entrez Gene: SCARB2 scavenger receptor class B, member 2". "Protein sequence of human SCARB2 (Uniprot ID: Q14108)". Cardiac ... Mulcahy JV, Riddell DR, Owen JS (Feb 2004). "Human scavenger receptor class B type II (SR-BII) and cellular cholesterol efflux ... "Intraretinal lipid transport is dependent on high density lipoprotein-like particles and class B scavenger receptors". ... "Scavenger receptor B2 is a cellular receptor for enterovirus 71". Nature Medicine. 15 (7): 798-801. doi:10.1038/nm.1992. PMID ...
SR-BI functions as a receptor for high-density lipoprotein. Scavenger receptor class B, type I (SR-BI) is an integral membrane ... Valacchi G, Sticozzi C, Lim Y, Pecorelli A (July 2011). "Scavenger receptor class B type I: a multifunctional receptor". Annals ... Connelly MA, Williams DL (June 2004). "Scavenger receptor BI: a scavenger receptor with a mission to transport high density ... "Phosphatidylserine binding of class B scavenger receptor type I, a phagocytosis receptor of testicular sertoli cells". The ...
1996). "Structures of class A macrophage scavenger receptors. Electron microscopic study of flexible, multidomain, fibrous ... Kosswig N, Rice S, Daugherty A, Post SR (2003). "Class A scavenger receptor-mediated adhesion and internalization require ... This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by ... and interspecies reactivities of monoclonal antibodies against human class A macrophage scavenger receptors". Atherosclerosis. ...
"Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice". ... TRPV1 is the transient receptor potential cation channel subfamily V member 1 receptor (also termed capsaicin receptor or ... 13(S)-HODE stimulates the proliferation of human MCF-7 estrogen receptor positive and MBA-MD-231 estrogen receptor negative ... a scavenger receptor for oxidized low density lipoproteins, native lipoproteins, oxidized phospholipids, and long-chain fatty ...
The protein itself belongs to the class B scavenger receptor family which includes receptors for selective cholesteryl ester ... It imports fatty acids inside cells and is a member of the class B scavenger receptor family of cell surface proteins. CD36 ... April 2000). "Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in ... On macrophages CD36 forms part of a non-opsonic receptor (the scavenger receptor CD36/alpha-v beta-3 complex) and is involved ...
... of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B ... "Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I". Proc. Natl. Acad ... Silver DL (2002). "A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface ...
2002). "The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus". The EMBO Journal ... This work would later inform the development of a novel class of antiretroviral agents, HIV integrase inhibitors, and ...
"MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in ...
Basis for the Recognition of Oxidized Phospholipids in Oxidized Low Density Lipoproteins by Class B Scavenger Receptors CD36 ... "Oxidized high-density lipoprotein inhibits platelet activation and aggregation via scavenger receptor BI". Blood. 111 (4): 1962 ... of the Binding Site for Specific Oxidized Phospholipids and Oxidized Low Density Lipoprotein of Scavenger Receptor CD36". ...
The receptors for EV71 and CVA16 have been identified as P-selectin glycoprotein ligand-1 and scavenger receptor class B, ... PMID 29111273 Nishimura Y, Shimizu H (2012). "Cellular receptors for human enterovirus species A." Front Microbiol. 3: 105. doi ...
"Macrophage Class A Scavenger Receptor-Mediated Phagocytosis of Escherichia coli: Role of Cell Heterogeneity, Microbial Strain, ... Phagocytes recognize bacteria directly [e.g., through the so-called scavenger receptor A which recognizes bacterial ... Human cells have receptors that recognize pathogen-associated molecular patterns (PAMPs). When bacteria bind to these receptors ... which coat the bacteria and are recognized by the Fcγ receptors and integrinαmβ2 (complement receptor 3). For instance, ...
Toll-like receptors(TLRs), the scavenger receptor, CD14, and Mac-1. PRRs can be divided into three classes: signaling PRRs that ... Thus TGF-β signaling involves a direct pathway from the receptors on the surface of a cell to the nucleus. Toll-like receptors ... class switching to IgE and IgG4 during the development of immune responses. Ig is a class of antibody found only in mammals ... effectors via EP2 and EP4 receptors signaling. EP2 and EP4 receptors signal primarily through stimulatory G protein (Gs), ...
At the enterocyte cell wall, β-carotene is taken up by the membrane transporter protein scavenger receptor class B, type 1 ( ... At the enterocyte cell wall, β-carotene is taken up by the membrane transporter protein scavenger receptor class B, type 1 ( ... β-carotene is taken into cells via receptor SCARB1. Human tissues differ in expression of SCARB1, and hence β-carotene content ...
Cai L, de Beer MC, de Beer FC, van der Westhuyzen DR (Jan 2005). "Serum amyloid A is a ligand for scavenger receptor class B ... These receptors include the G protein-coupled chemoattractant receptor FPR2 (formyl peptide receptor 2), believed to mediate ... The P2X7 purinergic receptor is another receptor used by SAA1 for a number of cellular functions including the activation of ... This effect is believed to be mediated through FPR2, a G protein-coupled chemoattractant receptor. The same receptor also ...
The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich ... the scavenger receptor cysteine-rich domain (SRCR). This domain may be implicated in the binding of extracellular molecules and ... SARS-CoV-2 uses the SARS-CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming. Cleavage of the ... domain in the stem region that has been examined through mutational analysis is the low density lipoprotein receptor class A ...
... and related proteins such as class A macrophage scavenger receptors, ectodysplasin A or the MARCO1 receptor, are also part of ... Cellular receptors for collagens belong to the family of β1 integrins. Collagen XXIII interacts in an ion-and conformation- ...
The taste receptors are able to detect enzymes in the water and help the fish identify if it is from a possible food source or ... The abyssal zone scavengers Coryphaenoides armatus possess one small mandible barbel that they use to search the seafloor for ... This class of genes are signalling genes that provide migrating cells directional information during morphogenesis. In most ...
... receptors identified for receptor-mediated endocytosis of nanoparticle delivery systems are the scavenger receptor class B type ... I (SR-BI), LDL receptor (LRP1), transferrin receptor, and insulin receptor. As long as a receptor exists on the endothelial ... ApoE constituents bind to nanoparticles, and then this complex binds to a low-density lipoprotein receptor (LDLR) in the BBB ... This mechanism also relies on certain receptors located on the luminal surface of endothelial cells of the BBB. Ligands coated ...
... β-carotene is taken up by the membrane transporter protein scavenger receptor class B, type 1 (SCARB1). Absorbed β-carotene is ... Unlike retinol, β-carotene is taken up by enterocytes by the membrane transporter protein scavenger receptor B1 (SCARB1). The ... Unlike retinol, β-carotene is taken up by enterocytes by the membrane transporter protein scavenger receptor B1 (SCARB1), which ... The receptors undergo a conformational change that causes co-repressors to dissociate from the receptors. Coactivators can then ...
Scavenger Receptor Class D, Member 1, SCARD1, and LAMP4. The mouse equivalent is known as "macrosialin". CD68 is functionally ... Cluster of differentiation Lysosome-associated membrane glycoprotein Scavenger receptor (immunology) GRCh38: Ensembl release 89 ... the scavenger receptor family, whose members typically function to clear cellular debris, promote phagocytosis, and mediate the ...
In rat it has been shown that LSECs express scavenger receptors (SR) class A, B, E and H. The latter exists as stabilin-1 (SR- ... Moreover, LSECs also express high levels of the macrophage mannose receptor (MMR) and the Fc-gamma receptor IIb2 (FcγRIIb2), ... The abundant expression of receptors such as the endocytic FcγRIIb2 and pattern recognition receptors (PRRs) i.e. toll like ... density lipoprotein receptor‐related protein‐1). The capacity of LSECs as scavengers of blood borne waste assigns an important ...
... activatory receptor on NK cells and by various receptors on other cells including Fc receptor and scavenger class A receptor. ... On T cells and B cells, trogocytosis is triggered when the T cell receptor (TCR) on T cells or B cell receptor (BCR) on B cells ... Patel, Dhaval M.; Arnold, Paula Y.; White, Gregory A.; Nardella, John P.; Mannie, Mark D. (15 November 1999). "Class II MHC/ ... Trogocytosis is specifically triggered by antigen receptor signalling on T and B cells, by killer inhibitory and killer ...
Pages 376-379 Characterization of the Isoflavone Pratensein as a Novel Transcriptional Up-Regulator of Scavenger Receptor Class ...
... may stand for: Macrophage scavenger receptor class A, a receptor found in macrophages New York Metropolitan Squash ...
... class F scavenger receptors (SCARF1, SCARF2), stabilins (STAB1, STAB2), agrin (AGRIN), angiopoietin-1 receptor (TEK), perlecan ... This leads to cell signalling through integrins and dystroglycan (and possibly other receptors) recruited to the adherent ... Neurons of the peripheral nervous system express integrin receptors that attach to laminins and promote neuroregeneration after ... sulphatides and the cell surface receptor dystroglycan. Laminin G-containing proteins appear to have a wide variety of roles in ...
As a class, ginsenosides exhibit a large variety of subtle and difficult-to-characterize biological effects when studied in ... Some ginsenosides have also been shown to be partial agonists of steroid hormone receptors. It is not known how these ... Ginsenosides have been observed to increase internal antioxidant enzymes and act as a free-radical scavenger. Ginsenosides Rg3 ... Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family ...
H 2S is also active in the brain, where it increases the response of the NMDA receptor and facilitates long term potentiation, ... Gasotransmitters is a class of neurotransmitters. The molecules are distinguished from other bioactive endogenous gaseous ... be carried to remote targets by scavengers and released there, and modulate functions of remote target cells; It is ... As such, its effects do not rely on the cognate membrane receptors. It can have endocrine, paracrine, and autocrine effects. In ...
... and melatonin receptor 2 (nanomolar binding affinity), both of which belong to the class of G-protein coupled receptors (GPCRs ... although melatonin receptor 1 is also Gq-coupled. Melatonin also acts as a high-capacity free radical scavenger within ... "Melatonin receptors , G protein-coupled receptors , IUPHAR/BPS Guide to Pharmacology". www.guidetopharmacology.org. Retrieved 7 ... Emet M, Ozcan H, Ozel L, Yayla M, Halici Z, Hacimuftuoglu A (June 2016). "A Review of Melatonin, Its Receptors and Drugs". The ...