Loading...
*  Exon junction complex
The core of the EJC contains the protein eukaryotic initiation factor 4A-III (eIF4A-III; a DEAD-box RNA helicase) bound to an ... Within this complex, UPF2 and UPF3 act cooperatively to promote ATPase and RNA helicase of UPF1. The EJC core stably anchors ... UAP56 is recognized as an RNA helicase but acts as a splicing factor required for early splicesome assembly. Another factor ... "NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity". Nature Structural ...
*  DDX39
... and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ... ATP-dependent RNA helicase DDX39 is an enzyme that in humans is encoded by the DDX39 gene. This gene encodes a member of the ... Aug 1995). "The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family". ... Sugiura T, Sakurai K, Nagano Y (2007). "Intracellular characterization of DDX39, a novel growth-associated RNA helicase". Exp. ...
*  Primosome
The primosome attaches 1-10 RNA nucleotides to the single stranded DNA creating a DNA-RNA hybrid. This sequence of RNA is used ... The primosome consists of seven proteins: DnaG primase, DnaB helicase, DnaC helicase assistant, DnaT, PriA, Pri B, and PriC. At ... The RNA bases are ultimately replaced with DNA bases by RNase H nuclease (eukaryotes) or DNA polymerase I nuclease (prokaryotes ... Then the DnaB-DnaC helicase complex attaches along with DnaT. This structure is referred to as the pre-primosome. Finally, DnaG ...
*  RIG-I
... are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA ... "The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses". Nature Immunology ... "The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses". Nature Immunology ... RIG-I contains a RNA helicase-DEAD box motifs and a caspase recruitment domain (CARD). RIG-I is involved in viral double- ...
*  RNA Helicase A
The RNA-binding domains and RGG box influence and regulate RNA helicase activity.The DHX9 gene is located on the long arm q of ... DEAD/DEAH box helicases are proteins, and are putative RNA helicases. They are implicated in a number of cellular processes ... This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as ... Zhang S, Grosse F (Apr 1997). "Domain structure of human nuclear DNA helicase II (RNA helicase A)". The Journal of Biological ...
*  RNA helicase database
The RNA helicase database stores data (sequence, structures...) about RNA helicases. Helicase Jankowsky, Anja; Guenther Ulf- ... "The RNA helicase database". Nucleic Acids Res. England. 39 (Database issue): D338-41. doi:10.1093/nar/gkq1002. PMC 3013637 . ...
*  Vasa gene
Vasa is an RNA binding protein with an ATP-dependent RNA helicase that is a member of the DEAD box family of proteins. The vasa ... The Vasa gene is a member of the DEAD box family of RNA helicases in Drosophila melanogaster. Its human ortholog, Ddx4, is ... Linder P, Lasko P (April 2006). "Bent out of shape: RNA unwinding by the DEAD-box helicase Vasa". Cell. 125 (2): 219-21. doi: ... It uses ATP dependent RNA helicase catalytic activity to regulate the translation of multiple mRNAs. Vasa unwinds the duplex ...
*  ZGRF1
These paralogs operate under a SPF1 RNA helicase motif. Mov10, a paralog, and probable RNA helicase is required for RNA- ... A majority of these proteins are in the RNA helicase family. There are no known paralogs to the large N-terminal portion of the ... Jankowsky E (Jan 2011). "RNA helicases at work: binding and rearranging". Trends in Biochemical Sciences. 36 (1): 19-29. doi: ... with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA ...
*  Rhodococcus fascians
The hyp codifies for an RNA-helicase; mutants for this gene are hypervirulent. Also, hyp is involved in post transcriptional ...
*  DDX1
2002). "An RNA helicase, DDX1, interacting with poly(A) RNA and heterogeneous nuclear ribonucleoprotein K". J. Biol. Chem. 277 ... are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ... "An RNA helicase, DDX1, interacting with poly(A) RNA and heterogeneous nuclear ribonucleoprotein K". J. Biol. Chem. United ... ATP-dependent RNA helicase DDX1 is an enzyme that in humans is encoded by the DDX1 gene. DEAD box proteins, characterized by ...
*  EIF4A
Caruthers JM, Johnson ER, McKay DB (Nov 2000). "Crystal structure of yeast initiation factor 4A, a DEAD-box RNA helicase". ... Pause A, Sonenberg N (Jul 1992). "Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor ... In addition these proteins are helicases that function to unwind double-stranded RNA. The mechanisms governing the basic ... Lin D, Pestova TV, Hellen CU, Tiedge H (May 2008). "Translational control by a small RNA: dendritic BC1 RNA targets the ...
*  DEAD/DEAH box helicase
... a representative DEAD-box RNA helicase". RNA. 5 (12): 1526-34. doi:10.1017/S1355838299991410. PMC 1369875 . PMID 10606264. de ... The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ... Aubourg S, Kreis M, Lecharny A (January 1999). "The DEAD box RNA helicase family in Arabidopsis thaliana". Nucleic Acids Res. ... The DEAD/DEAH box helicases are a family of proteins whose purpose is to unwind nucleic acids. ...
*  DDX17
... are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ... Probable ATP-dependent RNA helicase DDX17 (p72) is an enzyme that in humans is encoded by the DDX17 gene. DEAD box proteins, ... Wilson BJ, Bates GJ, Nicol SM, Gregory DJ, Perkins ND, Fuller-Pace FV (Aug 2004). "The p68 and p72 DEAD box RNA helicases ... Wilson BJ, Bates GJ, Nicol SM, Gregory DJ, Perkins ND, Fuller-Pace FV (2005). "The p68 and p72 DEAD box RNA helicases interact ...
*  Cyclopentenone prostaglandins
eIF4A: eIF4A is an RNA helicase is essential for protein translation. 15-Deoxy-Δ12,14-PGJ2 forms an adduct with cysteine 264 in ...
*  RHAU
... (RNA Helicase associated with AU-rich element, also known as DHX36 or G4R1) is a 114-kDa human RNA helicase of the DEAH- ... "Recruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain". The Journal of Biological Chemistry. ... "Characterizing functional domains of the RNA helicase RHAU involved in subcellular localization and RNA interaction" (PDF). [ ... Abdelhaleem M, Maltais L, Wain H (June 2003). "The human DDX and DHX gene families of putative RNA helicases". Genomics. 81 (6 ...
*  DHX36
... are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ... "Recruitment of the RNA helicase RHAU to stress granules via a unique RNA-binding domain". J. Biol. Chem. 283 (50): 35186-98. ... "Characterizing functional domains of the RNA helicase RHAU involved in subcellular localization and RNA interaction" (PDF). [ ... Probable ATP-dependent RNA helicase DHX36 also known as DEAH box protein 36 (DHX36) or MLE-like protein 1 (MLEL1) or G4 ...
*  DEAD box
Tanaka N, Schwer B (July 2005). "Characterization of the NTPase, RNA-binding, and RNA helicase activities of the DEAH-box ... DDX3X DEAD/DEAH box helicase RNA helicase Walker A motif Johnson, E. R.; McKay, D. B. (1999). "Crystallographic structure of ... a representative DEAD-box RNA helicase". RNA. 5 (12): 1526-1534. doi:10.1017/S1355838299991410. PMC 1369875 . PMID 10606264. ... DEAD box proteins are considered to be RNA helicases and many have been found to be required in cellular processes such as pre- ...
*  DDX31
... are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ... Abdelhaleem M, Maltais L, Wain H (2004). "The human DDX and DHX gene families of putative RNA helicases". Genomics. 81 (6): 618 ...
*  PRMT1
Smith WA, Schurter BT, Wong-Staal F, David M (May 2004). "Arginine methylation of RNA helicase a determines its subcellular ... Côté J, Boisvert FM, Boulanger MC, Bedford MT, Richard S (January 2003). "Sam68 RNA binding protein is an in vivo substrate for ... "The Arginine-1493 Residue in QRRGRTGR1493G Motif IV of the Hepatitis C Virus NS3 Helicase Domain Is Essential for NS3 Protein ... "Methylation of SPT5 regulates its interaction with RNA polymerase II and transcriptional elongation properties". Mol. Cell. 11 ...
*  SARNP
Sugiura T, Sakurai K, Nagano Y (2007). "Intracellular characterization of DDX39, a novel growth-associated RNA helicase". Exp. ...
*  Frequency (gene)
It interacts at all times with FRH (FRQ-interacting RNA helicase; an essential DEAD box-containing RNA helicase in Neurospora) ... Cheng P, He Q, He Q, Wang L, Liu Y (January 2005). "Regulation of the Neurospora circadian clock by an RNA helicase". Genes & ... Shi M, Collett M, Loros JJ, Dunlap JC (2010). "FRQ-interacting RNA helicase mediates negative and positive feedback in the ... Hurley JM, Larrondo LF, Loros JJ, Dunlap JC (December 2013). "Conserved RNA helicase FRH acts nonenzymatically to support the ...
*  Potyvirus
CI (~71 kDa) is an RNA helicase with ATPase activity. It is also involved in membrane attachment. NIa (~50 kDa) is cleaved into ... NIb (~59 kDa) is an RNA-dependent RNA polymerase. The functions of the 6K1 (~6 kDa) is not known. 6K2 (~6 kDa) protein, having ... Replication follows the positive stranded RNA virus replication model. Positive-stranded RNA virus transcription is the method ... It also interacts with eukaryotic initiation factor 4 (eIF4). It acts as a viral RNA silencing suppressor. The function of P3 ...
*  Semliki Forest virus
Gomez De Cedrón, M.; Ehsani, N.; Mikkola, M. L.; García, J. A.; Kääriäinen, L. (1999). "RNA helicase activity of Semliki Forest ... Replication occurs via a negative strand intermediate giving rise to a full length genomic RNA for export in new virions and a ... The Semliki Forest virus is a positive-stranded RNA virus with a genome of approximately 13,000 base pairs which encodes nine ... The 5' two thirds of the genome encode four non-structural proteins concerned with RNA synthesis and the structural proteins ...
*  EP300
Rossow KL, Janknecht R (January 2003). "Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300". ...
*  DHX32
... are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ... Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 is an enzyme that in humans is encoded by the DHX32 gene. ... 2007). "Nuclear and mitochondrial localization of the putative RNA helicase DHX32". Exp. Mol. Pathol. 81 (3): 245-8. doi: ... Abdelhaleem M (2002). "The novel helicase homologue DDX32 is down-regulated in acute lymphoblastic leukemia". Leuk. Res. 26 (10 ...
*  DDX46
... are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary ... Probable ATP-dependent RNA helicase DDX46 is an enzyme that in humans is encoded by the DDX46 gene. This gene encodes a member ... "Prp5 bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA". EMBO J. 23 (2): 376-85. doi:10.1038/sj. ...
*  Chris Higgins (academic)
Py, B. A.; Higgins, C. F.; Krisch, H. M.; Carpousis, A. J. (1996). "A DEAD-box RNA helicase in the Escherichia coli RNA ...