Retinoblastoma-binding protein 8 is a protein that in humans is encoded by the RBBP8 gene. The protein encoded by this gene is ... It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This ... "Entrez Gene: RBBP8 retinoblastoma binding protein 8". Li S, Ting NS, Zheng L, Chen PL, Ziv Y, Shiloh Y, Lee EY, Lee WH (July ... "Molecular cloning and characterization of a novel retinoblastoma-binding protein". Genomics. 51 (3): 351-8. doi:10.1006/geno. ...
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell ... "Entrez Gene: RBBP9 retinoblastoma binding protein 9". Chen JZ, Yang QS, Wang S, Meng XF, Ying K, Xie Y, Ma YM (Aug 2002). " ... RBBP9 has been shown to interact with Retinoblastoma protein. GRCh38: Ensembl release 89: ENSG00000089050 - Ensembl, May 2017 ... "A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability". Nature Genetics. 19 (4): ...
It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The ... Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene. This protein is a ubiquitously ... Huang S, Lee WH, Lee EY (1991). "A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene ... "Entrez Gene: RBBP7 retinoblastoma binding protein 7". "Peripheral blood lymphocytes data for Rbbp7". Wellcome Trust Sanger ...
Retinoblastoma-binding protein 5 is a protein that in humans is encoded by the RBBP5 gene. The protein encoded by this gene is ... The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. ... It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. ... "Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping". Genomics. 27 (3): 511-9 ...
The Dyson Lab studies the retinoblastoma protein. Working as a post-doctoral fellow in the laboratory of Dr. Ed Harlow, Dyson ... demonstrated that the retinoblastoma protein can form complexes in vitro with the E7 oncoprotein of Human papilloma virus type- ... "The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product". Science. 243 (4893): 934-7. ...
It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This ... "Entrez Gene: RBBP4 retinoblastoma-binding protein 4". Pavlopoulos E, Jones S, Kosmidis S, Close M, Kim C, Kovalerchik O, Small ... "RBBP4 retinoblastoma binding protein 4 [Homo sapiens (human)]". Home - Gene - NCBI. Bethesda, MD: National Center for ... Histone-binding protein RBBP4 (also known as RbAp48, or NURF55) is a protein that in humans is encoded by the RBBP4 gene. This ...
Retinoblastoma-binding protein 6 is a protein that in humans is encoded by the RBBP6 gene. The retinoblastoma tumor suppressor ... "Entrez Gene: RBBP6 retinoblastoma binding protein 6". Chibi M, Meyer M, Skepu A, G Rees DJ, Moolman-Smook JC, Pugh DJ (Dec 2008 ... "cDNA sequence and chromosomal localization of a novel human protein, RBQ-1 (RBBP6), that binds to the retinoblastoma gene ... pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated ...
DNA dependent polymerase alpha (Pol α) has been shown to interact with Retinoblastoma protein, PARP1 and RBMS1. DNA Polymerase ... Takemura M, Kitagawa T, Izuta S, Wasa J, Takai A, Akiyama T, Yoshida S (November 1997). "Phosphorylated retinoblastoma protein ... Niki T, Galli I, Ariga H, Iguchi-Ariga SM (June 2000). "MSSP, a protein binding to an origin of replication in the c-myc gene, ... Coverley D, Kenny MK, Lane DP, Wood RD (1992). "A role for the human single-stranded DNA binding protein HSSB/RPA in an early ...
HDACs are involved in the pathway by which the retinoblastoma protein (pRb) suppresses cell proliferation. The pRb protein is ... Brehm A, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T (February 1998). "Retinoblastoma protein recruits histone ... Non-histone proteins such as transcription factors are also targets for acetylation with varying functional effects. ... through modulating that the acetylation/deactylation of histones and/or non-histone proteins such as transcription factors. ...
"The binding domain structure of retinoblastoma-binding proteins". Protein Science. 2 (2): 155-64. doi:10.1002/pro.5560020204. ... Protein-protein interactions between T-antigen and DNA polymerase-alpha directly stimulate replication of the virus genome. T- ... SV40 large TAg, other polyomavirus large T antigens, adenovirus E1a proteins, and oncogenic human papillomavirus E7 proteins ... "Molecular determinants for the complex formation between the retinoblastoma protein and LXCXE sequences". The Journal of ...
CDKCs bind and phosphorylate members of the retinoblastoma (Rb) protein family. Members of the Rb protein family are tumor ... Functions of the retinoblastoma protein. Bioessays. 1999 Nov;21(11):950-8. Lundberg AS, Weinberg RA. Functional inactivation of ... Activity of CDKCs is controlled by phosphorylation of target proteins, as well as binding of inhibitory proteins. Although ... is a protein complex formed by the association of an inactive catalytic subunit of a protein kinase, cyclin-dependent kinase ( ...
Retinoblastoma protein, Retinoblastoma-like protein 1, Retinoblastoma-like protein 2, SAP30, SATB1, SIN3A, SIN3B, SPEN, SUDS3, ... It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell ... Nicolas E, Ait-Si-Ali S, Trouche D (August 2001). "The histone deacetylase HDAC3 targets RbAp48 to the retinoblastoma protein ... Brehm A, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T (February 1998). "Retinoblastoma protein recruits histone ...
Kouzarides, T.; Brehm, A.; Miska, E. A.; McCance, D. J.; Reid, J. L.; Bannister, A. J. (1998). "Retinoblastoma protein recruits ... Kouzarides, T.; Brehm, A.; Miska, E. A.; McCance, D. J.; Reid, J. L.; Bannister, A. J. (1998). "Retinoblastoma protein recruits ... "The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in ... Bartke, T.; Vermeulen, M.; Xhemalce, B.; Robson, S. C.; Mann, M.; Kouzarides, T. (2010). "Nucleosome-Interacting Proteins ...
... has been shown to interact with Retinoblastoma protein. GRCh38: Ensembl release 89: ENSG00000114316 - Ensembl, May 2017 ... 2001). "The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein". Oncogene. 20 (39): 5538-5542. doi:10.1038/ ... In the mouse and human the USP4 protein is encoded by a gene containing 22 exons. This protein is a member of cysteine ... Ubiquitin specific protease 4 (USP4) is an enzyme that cleaves ubiquitin from a number of protein substrates. Prior to the ...
It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB ... ARID4A has been shown to interact with Retinoblastoma protein. GRCh38: Ensembl release 89: ENSG00000032219 - Ensembl, May 2017 ... The protein encoded by this gene is a ubiquitously expressed nuclear protein. ... "Characterization of the retinoblastoma binding proteins RBP1 and RBP2". Oncogene. 8 (11): 3149-56. PMID 8414517. Otterson GA, ...
Klose, Rob (2007). "The retinoblastoma binding protein RBP2 is an H3K4 demethylase". Cell. 128 (5): 889-900. doi:10.1016/j.cell ... Klose, Rob (2013). "ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection". Biochem Soc Trans. 41 (3): ... he studied the methyl CpG binding protein MeCP2, part of the DNA methylation system, which is associated with Rett Syndrome. He ...
... to retinoblastoma protein which regulates cell proliferation. It was formerly known as Retinoblastoma Binding Protein 2 (RBP2 ... The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, ... of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. ... "Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein". Molecular and ...
Craven RJ, Cance WG, Liu ET (1995). "The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb". Cancer ... The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and ... FRK has been shown to interact with retinoblastoma protein. GRCh38: Ensembl release 89: ENSG00000111816 - Ensembl, May 2017 ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi:10.1038 ...
Lin-9 homolog is a protein that is encoded by the LIN9 gene in humans. LIN9 has been shown to interact with the retinoblastoma ... Osterloh L, von Eyss B, Schmit F, Rein L, Hübner D, Samans B, Hauser S, Gaubatz S (Jan 2007). "The human synMuv-like protein ... a pRB-associated protein". The EMBO Journal. 23 (23): 4627-38. doi:10.1038/sj.emboj.7600470. PMC 533054 . PMID 15538385. " ... "Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target ...
... the Cyclin D/Cdk4 complex phosphorylates Retinoblastoma protein (pRb). Once the Retinoblastoma protein has been phosphorylated ... Under non-dividing conditions (when the cell is in the G0 phase of the cell cycle), Retinoblastoma protein (Rb) is bound with ... The Cyclin D/Cdk4 complex is a multi-protein structure consisting of the proteins Cyclin D and cyclin-dependent kinase 4, or ... First and foremost, under non-dividing conditions multiple proteins can inhibit the Cyclin D/Cdk4 complex by binding Cdk4 and ...
Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA (1992). "Regulation of retinoblastoma protein functions by ... This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to ... G1/S-specific cyclin-E1 is a protein that in humans is encoded by the CCNE1 gene. The protein encoded by this gene belongs to ... Retinoblastoma-like protein 2, and SMARCA4. Cyclin E GRCh38: Ensembl release 89: ENSG00000105173 - Ensembl, May 2017 GRCm38: ...
This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell ... Nicolas E, Ait-Si-Ali S, Trouche D (August 2001). "The histone deacetylase HDAC3 targets RbAp48 to the retinoblastoma protein ... E2F Retinoblastoma protein GRCh38: Ensembl release 89: ENSG00000101412 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... Transcription factor E2F1 is a protein that in humans is encoded by the E2F1 gene. The protein encoded by this gene is a member ...
Nicolas E, Ait-Si-Ali S, Trouche D (August 2001). "The histone deacetylase HDAC3 targets RbAp48 to the retinoblastoma protein ... independent repression activities to retinoblastoma family proteins". Mol. Cell. Biol. 19 (10): 6632-41. doi:10.1128/mcb.19.10. ... "Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3". EMBO J. 19 (16): 4342-50. doi: ... HDAC3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from ...
... is composed of the following protein domains and motifs: retinoblastoma protein (pRb) binding motif; cyclin box ... The cyclin D1-CDK4 complex promotes passage through the G1 phase by inhibiting the retinoblastoma protein (pRb). Cyclin D1-CDK4 ... Dowdy SF, Hinds PW, Louie K, Reed SI, Arnold A, Weinberg RA (May 1993). "Physical interaction of the retinoblastoma protein ... Ikeguchi M, Sakatani T, Ueta T, Kaibara N (Sep 2001). "Cyclin D1 expression and retinoblastoma gene protein (pRB) expression in ...
Dowdy SF, Hinds PW, Louie K, Reed SI, Arnold A, Weinberg RA (1993). "Physical interaction of the retinoblastoma protein with ... This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 ... G1/S-specific cyclin-D3 is a protein that in humans is encoded by the CCND3 gene. The protein encoded by this gene belongs to ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. doi:10.1038/ ...
Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein. Mol. Biol. Cell. December 2002 ... endoplasmic reticulum unfolded protein response. · protein localization to nucleus. · sterol regulatory element binding protein ... It stays associated with the membrane through protein-protein interactions of itself and other membrane associated proteins, ... activation of signaling protein activity involved in unfolded protein response. · mitotic nuclear envelope disassembly. · ...