Woitach JT, Zhang M, Niu CH, Thorgeirsson SS (Aug 1998). "A retinoblastoma-binding protein that affects cell-cycle control and ... Retinoblastoma-like protein 2 is a protein that in humans is encoded by the RBL2 gene. Retinoblastoma-like protein 2 has been ... Fusco C, Reymond A, Zervos AS (Aug 1998). "Molecular cloning and characterization of a novel retinoblastoma-binding protein". ... Fusco C, Reymond A, Zervos AS (Aug 1998). "Molecular cloning and characterization of a novel retinoblastoma-binding protein". ...
"Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein". Molecular and ... "The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein". ... Welch PJ, Wang JY (November 1993). "A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl ... The retinoblastoma protein (protein name abbreviated Rb; gene name abbreviated Rb, RB or RB1) is a tumor suppressor protein ...
"Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein". Molecular and ... Woitach JT, Zhang M, Niu CH, Thorgeirsson SS (Aug 1998). "A retinoblastoma-binding protein that affects cell-cycle control and ... Retinoblastoma-like 1 (p107), also known as RBL1, is a protein that in humans is encoded by the RBL1 gene. The protein encoded ... Fusco C, Reymond A, Zervos AS (Aug 1998). "Molecular cloning and characterization of a novel retinoblastoma-binding protein". ...
Retinoblastoma-binding protein 8 is a protein that in humans is encoded by the RBBP8 gene. The protein encoded by this gene is ... It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This ... "Entrez Gene: RBBP8 retinoblastoma binding protein 8". Li S, Ting NS, Zheng L, Chen PL, Ziv Y, Shiloh Y, Lee EY, Lee WH (July ... Fusco C, Reymond A, Zervos AS (October 1998). "Molecular cloning and characterization of a novel retinoblastoma-binding protein ...
The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell ... "Entrez Gene: RBBP9 retinoblastoma binding protein 9". Chen JZ, Yang QS, Wang S, Meng XF, Ying K, Xie Y, Ma YM (Aug 2002). " ... Woitach JT, Zhang M, Niu CH, Thorgeirsson SS (Aug 1998). "A retinoblastoma-binding protein that affects cell-cycle control and ... "Cloning and expression of a novel retinoblastoma binding protein cDNA, RBBP10". Biochemical Genetics. 40 (7-8): 273-82. doi: ...
It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The ... Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene. This protein is a ubiquitously ... Zhang Q, Vo N, Goodman RH (2000). "Histone binding protein RbAp48 interacts with a complex of CREB binding protein and ... Huang S, Lee WH, Lee EY (1991). "A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene ...
Retinoblastoma-binding protein 5 is a protein that in humans is encoded by the RBBP5 gene. The protein encoded by this gene is ... The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. ... It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. ... "Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping". Genomics. 27 (3): 511-9 ...
It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This ... Zhang Q, Vo N, Goodman RH (2000). "Histone binding protein RbAp48 interacts with a complex of CREB binding protein and ... "Entrez Gene: RBBP4 retinoblastoma-binding protein 4". Pavlopoulos E, Jones S, Kosmidis S, Close M, Kim C, Kovalerchik O, Small ... Qian YW, Wang YC, Hollingsworth RE Jr, Jones D, Ling N, Lee EY (September 1993). "A retinoblastoma-binding protein related to a ...
"The binding domain structure of retinoblastoma-binding proteins". Protein Science. 2 (2): 155-64. doi:10.1002/pro.5560020204. ... The function of T-antigen is controlled by phosphorylation, which attenuates the binding to the SV40 origin. Protein-protein ... T-antigen also binds and inactivates tumor suppressor proteins (p53, p105-Rb). This causes the cells to leave G1 phase and ... The TAg has a CUL7-binding domain, a TP53-binding domain, a Zinc finger, and a Superfamily 3 ATPase/Helicase domain. It has two ...
"The retinoblastoma binding protein RBP2 is an H3K4 demethylase". Cell. 128 (5): 889-900. doi:10.1016/j.cell.2007.02.013. ISSN ... He continued to reveal the function of Tet proteins in zygotic DNA demethylation, germ cell development, and genomic imprinting ... By discovering two enzymatic activities of two PcG protein complexes, Zhang has contributed significantly to our current ... "Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification". Nature. 466 (7310): ...
It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB ... "Characterization of the retinoblastoma binding proteins RBP1 and RBP2". Oncogene. 8 (11): 3149-56. PMID 8414517. Otterson GA, ... forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses ... "Estrogen receptor isoform-specific regulation of the retinoblastoma-binding protein 1 (RBBP1) gene: roles of AF1 and enhancer ...
Klose, Rob (2007). "The retinoblastoma binding protein RBP2 is an H3K4 demethylase". Cell. 128 (5): 889-900. doi:10.1016/j.cell ... where he studied the methyl CpG binding protein MeCP2, part of the DNA methylation system, which is associated with Rett ... Klose, Rob (2005). "DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG". Mol. Cell ... Klose, Rob (2013). "ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection". Biochem Soc Trans. 41 (3): ...
"Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein". Molecular and ... "Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein". Molecular and ... to retinoblastoma protein which regulates cell proliferation. It was formerly known as Retinoblastoma Binding Protein 2 (RBP2 ... The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, ...
The Dyson Lab studies the retinoblastoma protein. Working as a post-doctoral fellow in the laboratory of Dr. Ed Harlow, Dyson ... "The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product". Science. 243 (4893): 934-7. ... demonstrated that the retinoblastoma protein can form complexes in vitro with the E7 oncoprotein of Human papilloma virus type- ... This result implicated pRB binding to E7 as a step in human papilloma virus-associated carcinogenesis. More recently, Dyson's ...
Chan SW, Hong W (July 2001). "Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated ... "Entrez Gene: DBI diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)". Kos M, Reid G, Denger ... March 2000). "Tamoxifen-bound estrogen receptor (ER) strongly interacts with the nuclear matrix protein HET/SAF-B, a novel ... March 2000). "The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action". Proceedings ...
Choubey D, Lengyel P (Mar 1995). "Binding of an interferon-inducible protein (p202) to the retinoblastoma protein". The Journal ... Tumor suppressor p53-binding protein 1 also known as p53-binding protein 1 or 53BP1 is a protein that in humans is encoded by ... "Entrez Gene: TP53BP1 tumor protein p53 binding protein 1". Bouwman P, Aly A, Escandell JM, Pieterse M, Bartkova J, van der ... "The 8-kDa dynein light chain binds to p53-binding protein 1 and mediates DNA damage-induced p53 nuclear accumulation". The ...
"Pax-6 interactions with TATA-box-binding protein and retinoblastoma protein". Invest. Ophthalmol. Vis. Sci. 40 (7): 1343-50. ... Sp1 and cAMP-response-element-binding protein-binding protein (CBP/p300)". Biochem. J. 339 (3): 751-8. doi:10.1042/0264-6021: ... The TATA-binding protein (TBP) is a general transcription factor that binds specifically to a DNA sequence called the TATA box ... gene is mediated by interactions of Msx1 protein with a multi-protein transcriptional complex containing TATA-binding protein, ...
... have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle ... Lees JA, Saito M, Vidal M, Valentine M, Look T, Harlow E, Dyson N, Helin K (Dec 1993). "The retinoblastoma protein binds to a ... Transcription factor E2F3 is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member ... "Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members". ...
Retinoblastoma-binding protein 6 is a protein that in humans is encoded by the RBBP6 gene. The retinoblastoma tumor suppressor ... "Entrez Gene: RBBP6 retinoblastoma binding protein 6". Chibi M, Meyer M, Skepu A, G Rees DJ, Moolman-Smook JC, Pugh DJ (Dec 2008 ... "cDNA sequence and chromosomal localization of a novel human protein, RBQ-1 (RBBP6), that binds to the retinoblastoma gene ... pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated ...
... have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle ... Lees JA, Saito M, Vidal M, Valentine M, Look T, Harlow E, Dyson N, Helin K (January 1994). "The retinoblastoma protein binds to ... Transcription factor E2F2 is a protein that in humans is encoded by the E2F2 gene. The protein encoded by this gene is a member ... "Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members". ...
Hinds PW, Mittnacht S, Dulic V, Arnold A, Reed SI, Weinberg RA (September 1992). "Regulation of retinoblastoma protein ... Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase of the cell cycle that determines ... Cyclin E/CDK2 phosphorylates retinoblastoma protein (Rb) to promote G1 progression. Hyper-phosphorylated Rb will no longer ... Protein pages needing a picture, Genes on human chromosome 19, Genes on human chromosome 8, Cell cycle regulators, Proteins). ...
... and retinoblastoma-binding protein". The Journal of Biological Chemistry. 280 (31): 28507-18. doi:10.1074/jbc.M413687200. PMID ... "N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso". Molecular Cell. 12 (3): 723-34 ... This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with a JmjN domain, a JmjC domain, a JD2H ... Zhang D, Yoon HG, Wong J (August 2005). "JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human ...
2006). "The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta". J. Biol. Chem. 281 (2): 858-66. ... The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C ... 1998). "Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta". Nature. 394 (6694): 697-700. ... "Entrez Gene: DGKZ diacylglycerol kinase, zeta 104kDa". Luo, Bai; Prescott Stephen M; Topham Matthew K (Oct 2003). "Protein ...
2005). "Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein". J. Biol. Chem. 280 ( ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355-64. doi: ...
... encodes an actin-binding protein.[supplied by OMIM] ENC1 has been shown to interact with Retinoblastoma protein. Model ... Zhao L, Gregoire F, Sul HS (Jun 2000). "Transient induction of ENC-1, a Kelch-related actin-binding protein, is required for ... Ectoderm-neural cortex protein 1 is a protein that in humans is encoded by the ENC1 gene. DNA damage and/or hyperproliferative ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ...
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of ... Cao J, Gao T, Stanbridge EJ, Irie R (Aug 2001). "RBP1L1, a retinoblastoma-binding protein-related gene encoding an antigenic ... AT-rich interactive domain-containing protein 4B is a protein that in humans is encoded by the ARID4B gene. ...
The MC160 protein binds heat shock protein 90, keeping it from stabilizing I Kappa Kinase (IKK). IKK is a protein that ... The MC007 protein sequesters retinoblastoma protein (pRb) on the mitochondria membrane, inactivating it. The pRb protein is ... When MC160 binds heat shock protein 90, IKK is degraded and the inhibitor remains bound to NF-κB, thus making NF-κB not ... The MC054 long protein binds Interleukin 18 which blocks its two binding sites. Interleukin-18 a pro-inflammatory cytokine ...
Qian YW, Wang YC, Hollingsworth RE, Jones D, Ling N, Lee EY (August 1993). "A retinoblastoma-binding protein related to a ... is essential for binding to DDB1 (a larger 127 kDa protein). Together, the two proteins form a UV-damaged DNA binding protein ... DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene. As indicated by Rapić-Otrin et al. in ... Zhu Q, Battu A, Ray A, Wani G, Qian J, He J, Wang QE, Wani AA (June 2015). "Damaged DNA-binding protein down-regulates ...
... have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle ... Yu X, Chini CC, He M, Mer G, Chen J (October 2003). "The BRCT domain is a phospho-protein binding domain". Science. 302 (5645 ... Nicolas E, Ait-Si-Ali S, Trouche D (August 2001). "The histone deacetylase HDAC3 targets RbAp48 to the retinoblastoma protein ... E2F Retinoblastoma protein GRCh38: Ensembl release 89: ENSG00000101412 - Ensembl, May 2017 GRCm38: Ensembl release 89: ...
"Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein". Molecular Biology of the Cell ... TMPO beta is a human homolog of the murine protein LAP2. LAP2 plays a role in the regulation of nuclear architecture by binding ... Furukawa K (Aug 1999). "LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction". Journal of ... Furukawa K (Aug 1999). "LAP2 binding protein 1 (L2BP1/BAF) is a candidate mediator of LAP2-chromatin interaction". Journal of ...