Tran KH, Ilsen PF (August 2007). "Peripheral retinal neovascularization in talc retinopathy". Optometry. 78 (8): 409-414. doi: ... Related retinal vasculature conditions include central retinal artery occlusion, central retinal vein occlusion and ... Cocaine is associated with retinal toxicity mainly through its negative impacts on the retinal vasculature. Cocaine use causes ... Hayreh SS (2014-12-08). "Retinal Survival Time and Visual Outcome in Central Retinal Artery Occlusion". Ocular Vascular ...
Retinal detachment: estimated at 0.36 percent. Choroidal neovascularization: estimated at 0.33 percent. Uveitis: estimated at ... Ruiz-Moreno JM, Alió JL (2003). "Incidence of retinal disease following refractive surgery in 9,239 eyes". Journal of ... Those with Fuchs' corneal endothelial dystrophy, corneal epithelial basement membrane dystrophy, retinal tears, autoimmune ... sometimes resulting in corneal neovascularization-the growth of blood vessels into the cornea. This causes a slight lengthening ...
... suppresses retinal neovascularization and endothelial cell proliferation. The antiangiogenic residues 24-57 were shown to ... This group was studying human retinal cell development by identifying secreted factors produced by the retinal pigmented ... "Pigment epithelium-derived factor suppresses ischemia-induced retinal neovascularization and VEGF-induced migration and growth ... "Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization". Journal of Cellular Physiology. 188 (2): ...
2001). "Pigment epithelium-derived factor inhibits retinal and choroidal neovascularization". J Cell Physiol. 188 (2): 253-263 ... 2011). "AAV Mediated GDNF Secretion From Retinal Glia Slows Down Retinal Degeneration in a Rat Model of Retinitis Pigmentosa". ... "rAAV.sFlt-1 gene therapy achieves lasting reversal of retinal neovascularization in the absence of a strong immune response to ... and the various retinal layers act as physical barriers for the delivery of drugs and vectors to the deeper retinal layers. ...
... has been implicated in ischemia-induced retinal neovascularization. Dysregulation of miRNA expression is thought to ... July 2008). "MicroRNAs regulate ocular neovascularization". Mol. Ther. 16 (7): 1208-16. doi:10.1038/mt.2008.104. PMC 3033219. ...
"Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization". Nature Medicine. 21 (5): 483-491. doi: ...
... inhibits pathologic retinal neovascularization". Invest. Ophthalmol. Vis. Sci. 53 (8): 5066-75. doi:10.1167/iovs.12-9627. PMID ...
Retinal neovascularization occurs in 20% of cases within the first 6-12 months of occlusion and depends on the area of retinal ... Central retinal vein occlusion Central retinal artery occlusion Branch retinal artery occlusion "Retina and vitreous". Basic ... Branch retinal vein occlusion is a common retinal vascular disease of the elderly. It is caused by the occlusion of one of the ... The second indication of laser treatment is in case of neovascularization. Retinal photocoagulation is applied to the involved ...
Wang W, Li Z, Sato T, Oshima Y (20 November 2012). "Tenomodulin inhibits retinal neovascularization in a mouse model of oxygen- ... Tnmd mRNA was detected in eyes, more specifically in the sclerocornea, tendon of the extraocular muscle and the retinal ... TNMD transduction in human retinal and umbilical vein endothelial cells resulted in reduced cell proliferation or migration, ...
Gendron RL, Good WV, Adams LC, Paradis H (2001). "Suppressed expression of tubedown-1 in retinal neovascularization of ... "Tubedown associates with cortactin and controls permeability of retinal endothelial cells to albumin". Journal of Cell Science ...
"Blockade of Sphingosine-1-phosphate Reduces Macrophage Influx and Retinal and Choroidal Neovascularization". Journal of ...
Choroidal neovascularization (CNV) is the most common complication associated with Serpiginous choroiditis. It is crucial to ... High-doses of intravenous pulse steroids can help preserve retinal function. Immunosupressive agents can help lengthen periods ... and recurrent bilateral inflammatory disease involving the retinal pigment epithelium (RPE), the choriocapillaries, and the ... initiate rapid and effective treatment to preserve retinal function. ...
IRMA can be difficult to distinguish from and is likely a precursor to retinal neovascularization. One way to distinguish IRMA ... IRMA is deeper in the retina than neovascularization, has blurrier edges, is more of a burgundy than a red, does not appear on ... from retinal neovascularization is to perform fluorescein angiography. Since IRMA blood vessels are patent, unlike neovascular ... the optic disc, and is usually seen after a shorter period of poorly controlled diabetes than neovascularization. Shimouchi, ...
"Blockade of Sphingosine-1-phosphate Reduces Macrophage Influx and Retinal and Choroidal Neovascularization". Journal of ...
implemented a telemedicine retinal screening program for low-income patients with diabetes as part of those patients' annual ... Angiogenesis and neovascularization tend to be a later manifestation of non-proliferative retinopathy. Many types of non- ... Retinal light toxicity. Eye (Lond). 2011; 25(1):1-14. "Use of the Hand-Held Ophthalmoscope , Harrison's Principles of Internal ... "Remote Retinal Screening Facilitates Diagnosis and Treatment of Retinopathy for Poor and/or Uninsured Patients With Diabetes in ...
The disease is identified by its three characteristic steps: vasculitis, occlusion, and retinal neovascularization, leading to ... It is characterized by three overlapping stages of venous inflammation (vasculitis), occlusion, and retinal neovascularization ... There may also be other signs that are identified via eye examination that can show retinal tears and retinal detachment that ... Eye floaters may develop indicating the possibility of the progression of the disease to a point where retinal detachment is a ...
Her laboratory developed and sold the 'Kimba' and 'Akimba' mouse models for advanced retinal neovascularization. She pioneered ...
Age-related macular degeneration is a retinal disease leading to neovascularization and thus impaired vision. Current treatment ... Retinal pigment epithelial cells can express IL-33 at both mRNA and protein levels. IL-33 expression is upregulated during ...
"Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis". ...
A tractional retinal detachment occurs when fibrovascular tissue, caused by an injury, inflammation or neovascularization, ... Retinal Detachment Resource Guide from the National Eye Institute (NEI) Overview of retinal detachment from eMedicine Retinal ... There are 4 main types of retinal detachment: Rhegmatogenous retinal detachment - A rhegmatogenous retinal detachment occurs ... "Diabetic Retinopathy: Retinal Disorders: Merck Manual Home Edition". Retrieved 2007-06-04. "IU Opt Online CE: Retinal Vascular ...
"Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman ... Pierce, Eric A.; Masland, Richard H.; Miller, Joan W. (2014). Retinal Disorders: Genetic Approaches to Diagnosis and Treatment ... 1994). "Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders". ... These studies strongly correlated VEGF protein with pathological ocular neovascularization both in patients and in experimental ...
Autocrine succinate signaling promotes retinal neovascularization, triggering the activation of angiogenic factors such as ... In the retina, succinate accumulates in retinal ganglion cells in response to ischemic conditions. ...
Also, vision can be impaired if the streaks progress to the fovea and damage the retinal pigment epithelium. Retinal fundus ... If choroidal neovascularization is present, treatment options like anti-VEGF medication, laser photocoagulation, photodynamic ... They were first described by Robert Walter Doyne in 1889 in a patient with retinal hemorrhages. In 1892, ophthalmologist ... The condition is usually asymptomatic, but decrease in vision may occur due to choroidal neovascularization. Angioid streaks ...
ODD can compress and eventually compromise the vasculature and retinal nerve fibers. Rarely, choroidal neovascularization may ... The central retinal artery and vein can be seen in the middle of the disc as it exits the scleral canal with the optic nerve to ... It consists of over one million retinal ganglion cell axons. The optic nerve head, or optic disc is the anterior end of the ... They are thought to be the remnants of the axonal transport system of degenerated retinal ganglion cells. ODD have also been ...
... and off-label bevacizumab are currently used for treatment of various retinal disease. Anti-VEGF antibodies such as the ... Corneal neovascularization (CNV) is the in-growth of new blood vessels from the pericorneal plexus into avascular corneal ... Corneal neovascularization has become more common worldwide with an estimated incidence rate of 1.4 million cases per year, ... Treatments for corneal neovascularization are predominately off-lab with a multitude of complications as a result. The desired ...
... and localized distortion caused by scarring of the sub-retinal layers. Complications include subretinal neovascularization and ... "Retinal Physician - Central Serous Chorioretinopathy and Topical NSAIDs". Retinal Physician. Archived from the original on 30 ... Roider J, Brinkmann R, Wirbelauer C, Laqua H, Birngruber R (August 1999). "Retinal sparing by selective retinal pigment ... It would appear that the presence of the bacteria is well correlated with visual acuity and other retinal findings following an ...
... retinal neovascularization leading, and/or glaucoma. Retinal microvascular disease is noninflammatory and resembles that of ... Retinal vasculopathy with cerebral leukocencephalopathy and systemic manifestations (RVCL or RVCL-S, also previously known as ... "Retinal vasculopathy with cerebral leukodystrophy , Genetic and Rare Diseases Information Center (GARD) - an NCATS Program". " ... "Treating Retinal Vasculopathy with Cerebral Leukoencephalopathy". www.pennmedicine.org. Retrieved 2023-07-16. (Articles with ...
"Choroidal neovascularization in a patient with adult foveomacular dystrophy and a mutation in the retinal degeneration slow ... 1995). "A peripherin/retinal degeneration slow mutation (Pro-210-Arg) associated with macular and peripheral retinal ... 1991). "The human retinal degeneration slow (RDS) gene: chromosome assignment and structure of the mRNA". Genomics. 10 (3): 733 ... Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically ...
Other less common causes of visual loss include retinal detachment, glaucoma, band keratopathy, cataract, vitreous hemorrhage, ... epiretinal membrane and choroidal neovascularization. Clinical signs include redness of the eye, pain, blurring of vision, ... The inciting event appears to be peripheral retinal perivasculitis and vascular occlusion leading to ocular inflammation, ...
... neovascularization). This leads to retinal detachment in that part of the eye, which is observed as some loss of vision or ... Once retinal detachment occurs, the case becomes a surgical emergency.[citation needed] Additionally, if the nevus is present ... The retinal pigment epithelium (RPE) can be captured as well, using autofluorescence, because the light waves can detect ... These drugs inactivate the growth factor (VEGF) to reduce neovascularization and swelling. If the choroidal nevus does ...