These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and ... Protein SSX1 is a protein that in humans is encoded by the SSX1 gene. The product of this gene belongs to the family of highly ... "Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM ... 1995). "Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human ...

These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and ... Protein SSX5 is a protein that in humans is encoded by the SSX5 gene. The product of this gene belongs to the family of highly ... "The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear ... protein, SSX2IP". Genes, Chromosomes & Cancer. 34 (3): 285-98. doi:10.1002/gcc.10073. PMID 12007189. S2CID 11734893. Güre AO, ...

These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and ... Protein SSX4 is a protein that in humans is encoded by the SSX4 gene. The product of this gene belongs to the family of highly ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ... 2002). "The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel ...

These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and ... SSX family member 6, pseudogene is a protein that in humans is encoded by the SSX6 gene. This gene belongs to the family of ... highly homologous synovial sarcoma X (SSX) breakpoint proteins. ...

These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and ... Protein SSX2 is a protein that in humans is encoded by the SSX2 gene. The product of this gene belongs to the family of highly ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ... 2002). "The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel ...

This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the ... Retinoblastoma-binding protein 8 is a protein that in humans is encoded by the RBBP8 gene. The protein encoded by this gene is ... It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ...

"Entrez Gene: NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)". Wang M, Qanungo S, Crow MT, Watanabe M, Nieminen ... Nucleolar protein 3 is a protein that in humans is encoded by the NOL3 gene. Nol3 has been shown to be induced in multiple ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/ ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ...

Nuclear receptor co-repressor 2, PRKAR2A, and Zinc finger and BTB domain-containing protein 16. GRCh38: Ensembl release 89: ... Protein CBFA2T1 is a protein that in humans is encoded by the RUNX1T1 gene. The protein encoded by this gene is a putative zinc ... with serine/threonine protein kinases and heat shock protein HSP90 in human hematopoietic cell lines". Jpn. J. Cancer Res. 90 ( ... "Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins". Eur. J. Haematol. 71 (6): 439-47. ...

The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. ... Zinc finger protein 274 is a protein that in humans is encoded by the ZNF274 gene. This gene encodes a zinc finger protein ... ZNF274+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) FactorBook ZNF274 This article ... "Entrez Gene: ZNF274 zinc finger protein 274". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap ...

This single [repressor controls the transcription of the whole fad regulon. Binding of fadR is specifically inhibited by long ... In molecular biology, the fatty acid metabolism regulator protein FadR, is a bacterial transcription factor. Bacteria regulate ... This article incorporates text from the public domain Pfam and InterPro: IPR008920 (Protein families). ...

2000). "The FBP interacting repressor targets TFIIH to inhibit activated transcription". Mol. Cell. 5 (2): 331-41. doi:10.1016/ ... This protein has been shown to function as an ATP-dependent DNA helicase. Far upstream element-binding protein 1 has been shown ... Far upstream element-binding protein 1 is a protein that in humans is encoded by the FUBP1 gene. This gene encodes a ssDNA ... 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi: ...

The protein it encodes for is 344 amino acids in length. The protein itself is very acidic and is very rich in aspartic acid ... It also interacts with EWSR1, which functions as a transcriptional repressor. CCDC82 is a circulat-responsive gene. Circulat is ... Coiled-Coil Domain Containing protein 82 (CCDC82) is a protein that in humans, is encoded for by the gene of the same name, ... CCDC82 is known to interact with two proteins. It indirectly interacts with VHL, a gene that encodes for a tumor suppressor and ...

"Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins". Eur. J. Haematol. 71 (6): 439-47. ... Protein CBFA2T2 is a protein that in humans is encoded by the CBFA2T2 gene. In acute myeloid leukemia, especially in the M2 ... Zhang J, Kalkum M, Yamamura S, Chait BT, Roeder RG (2004). "E protein silencing by the leukemogenic AML1-ETO fusion protein". ... "Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins". Eur. J. Haematol. 71 (6): 439-47. ...

Interferon regulatory factor 2 binding protein 2 is a protein that in humans is encoded by the IRF2BP2 gene. This gene encodes ... Childs KS, Goodbourn S (2003). "Identification of novel co-repressor molecules for Interferon Regulatory Factor-2". Nucleic ... Carneiro FR, Ramalho-Oliveira R, Mognol GP, Viola JP (2011). "Interferon regulatory factor 2 binding protein 2 is a new NFAT1 ... "Entrez Gene: Interferon regulatory factor 2 binding protein 2". Retrieved 2017-01-06. ...

2000). "The human transcriptional repressor protein NAB1: expression and biological activity". Biochim. Biophys. Acta. 1493 (3 ... NGFI-A-binding protein 1 is a protein that in humans is encoded by the NAB1 gene. NAB1 has been shown to interact with Zif268. ... "Entrez Gene: NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)". Bonaldo MF, Lennon G, Soares MB (1997). "Normalization ... Russo MW, Sevetson BR, Milbrandt J (Aug 1995). "Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated ...

"Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins". Eur. J. Haematol. 71 (6): 439-47. ... Protein CBFA2T3 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3) is a protein that in humans is encoded ... "Interactions between the leukaemia-associated ETO homologues of nuclear repressor proteins". Eur. J. Haematol. 71 (6): 439-47. ... CBFA2T3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CBFA2T3 genome location ...

"KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions". Current Genomics. 14 (4): 268-78. doi: ... The C8orf48 protein is predicted to be a nuclear protein particularly located in the nuclear lamina. This protein does not ... C8orf48 is a protein that in humans is encoded by the C8orf48 gene. C8orf48 is a nuclear protein specifically predicted to be ... The protein C8orf48 is 319 amino acids in length. The molecular weight of this protein is 36.9 kDa and the isoelectric point is ...

One such protein pathway is the REST co-repressor complex pathway. There are also several non-coding RNAs that regulate neural ... Neuroepigenetic mechanisms involve proteins or protein pathways that regulate gene expression by adding, editing or reading ... In response to DNA damage, the FUS protein also interacts with histone deacetylase I, a protein employed in epigenetic ... The protein encoded by the FUS gene is employed in the DNA damage response. It is recruited to DNA double-strand breaks and ...

KRAB-ZNF proteins are known to be repressors. Therefore, when a KRAB-ZNF protein, such as ZNF548, is bound to DNA and ... "Protein Abundance Database entry on ZNF548". PAXdb. "The Human Protein Atlas entry on ZNF548". The Human Protein Atlas. Sügis E ... COFACTOR: improved protein function prediction by combining structure, sequence and protein-protein interaction information. ... Zinc Finger Protein 548 (ZNF548) is a human protein encoded by the ZNF548 gene which is located on chromosome 19. It is found ...

In repressors E2F4 and E2F5, pocket protein binding (more often p107 and p130 than pRB) mediates recruitment of repression ... Most E2F have a pocket protein binding domain. Pocket proteins such as pRB and related proteins p107 and p130, can bind to E2F ... E2F7 and E2F8 proteins can function as repressors independently of DP interaction. They are unique in having a duplicated ... The balance between repressor and activator E2F regulate cell cycle progression. When activator E2F family proteins are knocked ...

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic ... Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in ... Eukaryotic translation initiation factor 4E-binding protein 1 (also known as 4E-BP1) is a protein that in humans is encoded by ... Feigenblum D, Schneider RJ (1996). "Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 ...

Veal E, Eisenstein M, Tseng ZH, Gill G (Sep 1998). "A cellular repressor of E1A-stimulated genes that inhibits activation by ... Retinoblastoma-like protein 2 is a protein that in humans is encoded by the RBL2 gene. Retinoblastoma-like protein 2 has been ... Li Y, Graham C, Lacy S, Duncan AM, Whyte P (Dec 1993). "The adenovirus E1A-associated 130-kD protein is encoded by a member of ... Li Y, Graham C, Lacy S, Duncan AM, Whyte P (Dec 1993). "The adenovirus E1A-associated 130-kD protein is encoded by a member of ...

"Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor". Nature. 534 (7608): 558-61. ... A Approximate molecular weight for human proteins. In addition to the major proteins encompassing the eIF4F trimer, the eIF4F ... The eIF4F proteins interact with a number of different binding partners, and there are multiple genetic isoforms of eIF4A, ... The eIF4F complex is composed of three non-identical subunits: the DEAD-box RNA helicase eIF4A, the cap-binding protein eIF4E, ...

Dennis CA, Glykos NM, Parsons MR, Phillips SE (March 2002). "The structure of AhrC, the arginine repressor/activator protein ... AhrC endodes an arginine repressor protein which represses synthesis of arginine biosynthetic enzymes and activates arginine ... It is a dual-function RNA which acts both as a protein-coding RNA and as a regulatory sRNA. SR1 RNA is involved in the ... Licht A, Brantl S (October 2009). "The transcriptional repressor CcpN from Bacillus subtilis uses different repression ...

Johnstone RW, Kerry JA, Trapani JA (1998). "The human interferon-inducible protein, IFI 16, is a repressor of transcription". J ... The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The ... IFI16+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ... Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional ...

Veal E, Eisenstein M, Tseng ZH, Gill G (Sep 1998). "A cellular repressor of E1A-stimulated genes that inhibits activation by ... "Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions". Proceedings ... Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 Large T-antigen, with ... Retinoblastoma-like 1 (p107), also known as RBL1, is a protein that in humans is encoded by the RBL1 gene. The protein encoded ...

November 2002). "Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity". Genes & ... Sonic hedgehog protein (SHH) is encoded for by the SHH gene. The protein is named after the character Sonic the Hedgehog. This ... SHH is located on chromosome seven and initiates the production of Sonic Hedgehog protein. This protein sends short- and long- ... Vitronectin is another protein that is induced by SHH; it acts as an obligate co-factor for SHH signaling in the neural tube. ...

"Dual interactions of the translational repressor Paip2 with poly(A) binding protein". Mol. Cell. Biol. 21 (15): 5200-13. doi: ... Polyadenylate-binding protein-interacting protein 2 is a protein that in humans is encoded by the PAIP2 gene. PAIP2 has been ... Onesto C, Berra E, Grépin R, Pagès G (2004). "Poly(A)-binding protein-interacting protein 2, a strong regulator of vascular ... "Entrez Gene: PAIP2 poly(A) binding protein interacting protein 2". Khaleghpour K, Kahvejian A, De Crescenzo G, Roy G, Svitkin ...

"Myogenic repressor I-mfa interferes with the function of Zic family proteins". Biochem. Biophys. Res. Commun. 320 (1): 233-40. ... This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, ... "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ...

This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding ... Emery P, Durand B, Mach B, Reith W (May 1996). "RFX proteins, a novel family of DNA binding proteins conserved in the ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ... The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to ...

"Coordinated histone modifications mediated by a CtBP co-repressor complex". Nature. 422 (6933): 735-8. doi:10.1038/nature01550 ... Zinc finger protein 516 is a protein that in humans is encoded by the ZNF516 gene. Zinc-finger proteins bind nucleic acids and ... This gene encodes a zinc-finger protein, and belongs to the Krüppel C2H2-type zinc-finger protein family. It may be involved in ... "Entrez Gene: Zinc finger protein 516". Shaffer JR, Feingold E, Wang X, Lee M, Tcuenco K, Weeks DE, Weyant RJ, Crout R, McNeil ...

Adipocyte Enhancer-Binding Protein is a zinc finger protein that in humans is encoded by the evolutionarily well-conserved gene ... AEBP2 is a DNA-binding transcriptional repressor. It may interact with and stimulate the activity of the PRC2 complex. AEBP2 ... and was therefore named Adipocyte Enhancer Binding Protein 2. AEBP2 is a potential targeting protein for the mammalian Polycomb ... Kim H, Kang K, Kim J (2009). "AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2". Nucleic Acids Res. ...