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*  BAH domain
The BAH domain might therefore play an important role by linking DNA methylation, replication and transcriptional regulation. ... replication and transcriptional regulation". FEBS Lett. 446 (1): 189-93. doi:10.1016/S0014-5793(99)00132-5. PMID 10100640. This ... as well as several proteins involved in transcriptional regulation. The BAH domain appears to act as a protein-protein ...
*  GC skew
In addition to mutations during DNA replication, transcriptional mutations can create strand specific nucleotide composition ... DNA replication is semi-conservative and an asymmetric process itself. This asymmetry is due the formation of the replication ... and replication terminal. Most prokaryotes and archaea contain only one DNA replication origin. The GC skew is positive and ... GC or AT skew changes sign at the boundaries of the two replichores, which correspond to DNA replication origin or terminus. ...
*  Retinoblastoma protein
... has the ability to reversibly inhibit DNA replication through transcriptional repression of DNA replication factors. Rb is able ... Within 72-96 hours of active Rb induction in A2-4 cells, the target DNA replication factor proteins-MCMs, RPA34, DBF4, RFCp37, ... Rb's role in repressing the transcription of cell cycle progression genes leads to the S-phase arrest that prevents replication ... Sterner JM, Dew-Knight S, Musahl C, Kornbluth S, Horowitz JM (May 1998). "Negative Regulation of DNA Replication by the ...
*  Origin recognition complex
"The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing". Cell. 83 ... ORC bound at replication origins serves as the foundation for assembly of the pre-replication complex (pre-RC), which includes ... ORC is a central component for eukaryotic DNA replication, and remains bound to chromatin at replication origins throughout the ... and begin replication down the chromosome. In order to have bidirectional replication, this process happens twice at an origin ...
*  Histone octamer
... nucleosomal DNA from the external environment but also lower their accessibility to cellular replication and transcriptional ... The two can be separated quite easily and often are during replication and transcription. Specific remodeling proteins are ... and it happens genome-wide during replication. Remodeling proteins work in three distinct ways: they can slide the DNA along ... "Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300". ...
*  Xenopus
"Non-transcriptional control of DNA replication by c-Myc". Nature. 448 (7152): 445-51. doi:10.1038/nature05953. PMID 17597761. ... Transgenic Xenopus for studying transcriptional regulation of human disease genes: Xenopus embryos develop rapidly, so ... replication fork stalling (ATR) or DNA interstrand crosslinks (FA proteins and ATR). Notably, several mechanisms and components ... "Mechanism of replication-coupled DNA interstrand crosslink repair". Cell. 134 (6): 969-980. doi:10.1016/j.cell.2008.08.030. ...
*  Myc
"Non-transcriptional control of DNA replication by c-Myc". Nature. 448 (7152): 445-51. doi:10.1038/nature05953. PMID 17597761. ... In addition, myc has a direct role in the control of DNA replication. Myc is activated upon various mitogenic signals such as ... Izumi H, Molander C, Penn LZ, Ishisaki A, Kohno K, Funa K (April 2001). "Mechanism for the transcriptional repression by c-Myc ... Gaubatz S, Imhof A, Dosch R, Werner O, Mitchell P, Buettner R, Eilers M (April 1995). "Transcriptional activation by Myc is ...
*  Stomatitis
Iron is necessary for the upregulation of transcriptional elements for cell replication and repair. Lack of iron can cause ...
*  Transgenerational epigenetic inheritance
"Differential H4 acetylation of paternal and maternal chromatin precedes DNA replication and differential transcriptional ... During replication, DNA polymerases working on the leading and lagging strands are coupled by the DNA processivity factor ... Zhang Z, Shibahara K, Stillman B (November 2000). "PCNA connects DNA replication to epigenetic inheritance in yeast". Nature. ... "Epigenetic properties of white-opaque switching in Candida albicans are based on a self-sustaining transcriptional feedback ...
*  Anti-Q RNA
... "pT181 plasmid replication is regulated by a countertranscript-driven transcriptional attenuator". Cell. 59 (2): 395-404. doi: ...
*  Replication timing
Hiratani I, Takebayashi S, Lu J, Gilbert DM (2009) Replication timing and transcriptional control: beyond cause and effect-- ... The temporal order of replication of all the segments in the genome, called its replication-timing program, can now be easily ... Another intriguing aspect of replication timing is that the temporal order of replication is disrupted in most cancers and in ... Replication timing refers to the order in which segments of DNA along the length of a chromosome are duplicated. In eukaryotic ...
*  Virophage
... s use the transcriptional machinery of these giant viruses for their own replication instead of the host's ... Virophages rely on the viral replication factory of the co-infecting giant virus for their own replication. One of the ... The virophage was named Sputnik and its replication relied entirely on the co-infection of ACMV and its cytoplasmic replication ... Their dependence upon the giant virus for replication often results in the deactivation of the giant viruses. The virophage may ...
*  KHDRBS3
... in the post-transcriptional regulation of HIV replication". J. Biol. Chem. 277 (8): 5778-84. doi:10.1074/jbc.M106836200. PMID ...
*  Rev (HIV)
"A second post-transcriptional trans-activator gene required for HLTV-III replication". Nature. 321 (6068): 412-417. Bibcode: ... Since Rev is absolutely necessary for HIV-1 replication and it is expressed early on in infection, it has been suggested that ... "High transdominant RevM10 protein levels are required to inhibit HIV-1 replication in cell lines and primary T-cells: ...
*  William A. Haseltine
"A Second post-Transcriptional Trans-activator Gene required for HTLV III Replication". Nature. 321 (6068): 412-417. Bibcode: ... Retrovirus replication continued to be a focus of his early research as a Harvard professor. This research led to fundamental ... Haseltine, WA (1988). "Replication and Pathogenesis of the AIDS Virus. (Plenary Lecture presented at the IVth International ... Sodroski, JG; Rosen CR; Goh WC; Haseltine WA (1985). "The Human T-Cell Leukemia Virus x-lor Region Encodes a Transcriptional ...
*  Bacteriophage P2
Late gene transcription is initiated from four late promotersonce DNA replication has started and the transcriptional activator ... Besides cox, the early operon contains two other genes which are essential for P2 DNA replication, genes A and B. Replication ... Liu, Y. and E. Haggård-Ljungquist, Studies of bacteriophage P2 DNA replication: localization of the cleavage site of the A ... All the four promotors have a region with a partial dyad symmetry centered around 55 bp downstream from the transcriptional ...
*  Human cytomegalovirus
... which are involved in viral DNA replication and further transcriptional regulation. Late genes are expressed during the ... Major risk factors for HCMV drug resistance are the residual capacity of the host's immune system to control viral replication ... Synthesis of the viral double-stranded DNA genome occurs at the host cell nucleus within specialized viral replication ... Penfold, M. E.; Mocarski, E. S. (1997-12-08). "Formation of cytomegalovirus DNA replication compartments defined by ...
*  Cyclin-dependent kinase 6
Jiang W, Wells NJ, Hunter T (May 1999). "Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6". Proceedings ... After its phosphorylation, pRb releases its binding partner E2F, a transcriptional activator, which in turn activates DNA ... replication. The CDK6 complex ensures a point of switch to commit to division responding to external signals, like mitogens and ...
*  SV40 large T antigen
Contains transcriptional promoters and enhancers plus the unique origin of DNA replication. After entering the cell, the viral ... and T-antigen directs transcription and replication. SV40 DNA replication is initiated by binding of large T-antigen to the ... TAg is a product of an early gene transcribed during viral infection by SV40, and is involved in viral genome replication and ... The SV40 genome is very small and does not encode all the information necessary for DNA replication. Therefore, it is essential ...
*  E2F
Among E2F transcriptional targets are cyclins, CDKs, checkpoints regulators, DNA repair and replication proteins. Nonetheless, ... and chromosomal replication (replication origin-binding protein HsOrc1 and MCM5). When cells are not proliferating, E2F DNA ... E2F-6 acts as a transcriptional repressor, but through a distinct, pocket protein independent manner. E2F-6 mediates repression ... E2F targets genes that encode proteins involved in DNA replication (for example DNA polymerase, thymidine kinase, dihydrofolate ...
*  Transcriptomics technologies
DNA replication, RNA splicing and Transcriptional regulation). Many of these ncRNAs affect disease states, including cancer, ... Therefore, the transcriptional start site of genes can be identified when the tags are aligned to a reference genome. ... Nagalakshmi U, Wang Z, Waern K, Shou C, Raha D, Gerstein M, Snyder M (June 2008). "The transcriptional landscape of the yeast ... Both spotted oligonucleotide arrays and Affymetrix high-density arrays were the method of choice for transcriptional profiling ...
*  AAA proteins
They are involved in processes such as DNA replication, protein degradation, membrane fusion, microtubule severing, peroxisome ... transcriptional activation, protein refolding, disassembly of protein complexes and protein aggregates. Dyneins, one of the ... AAA proteins are involved in protein degradation, membrane fusion, DNA replication, microtubule dynamics, intracellular ...
*  Transactivation domain
"The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain". Cell. 58 (4): ... Fukasawa T, Fukuma M, Yano K, Sakurai H (Feb 2001). "A genome-wide analysis of transcriptional effect of Gal11 in Saccharomyces ... Kim YJ, Björklund S, Li Y, Sayre MH, Kornberg RD (May 1994). "A multiprotein mediator of transcriptional activation and its ... Lim MK, Tang V, Le Saux A, Schüller J, Bongards C, Lehming N (Nov 2007). "Gal11p dosage-compensates transcriptional activator ...
*  Replication protein A2
Cho JM, Song DJ, Bergeron J, Benlimame N, Wold MS, Alaoui-Jamali MA (Sep 2000). "RBT1, a novel transcriptional co-activator, ... Single-stranded binding protein Replication protein A Replication protein A1 Replication protein A3 GRCh38: Ensembl release 89 ... Replication protein A 32 kDa subunit is a protein that in humans is encoded by the RPA2 gene. RPA2 has been shown to interact ... "Entrez Gene: RPA2 Replication protein A2, 32kDa". Otterlei M, Warbrick E, Nagelhus TA, Haug T, Slupphaug G, Akbari M, Aas PA, ...
*  BZLF1
ZEBRA binds to the oriLyt (lytic origin of replication) of the EBV genome. It acts as an essential transcriptional regulator ... 2010).A subset of replication proteins enhances origin recognition and lytic replication by the Epstein-Barr virus ZEBRA ... ZEBRA (BamHI Z Epstein-Barr virus replication activator, also known as Zta and BZLF1)) is an early lytic protein of EBV encoded ... Wang'ondu et al.(2015). DNA Damage Signaling Is Induced in the Absence of Epstein-Barr Virus (EBV) Lytic DNA Replication and in ...
*  NFIX
Liu Y, Bernard HU, Apt D (1997). "NFI-B3, a novel transcriptional repressor of the nuclear factor I family, is generated by ... Müller K, Mermod N (2000). "The histone-interacting domain of nuclear factor I activates simian virus 40 DNA replication in ... interference with transcriptional activation by NFI/CTF in a cell-type specific manner". Nucleic Acids Res. 22 (19): 3825-33. ... "DNA binding and transcriptional activation by the Ski oncoprotein mediated by interaction with NFI". Nucleic Acids Res. 25 (19 ...