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*  Angiotensin-converting enzyme 2
Renin-angiotensin system ACE inhibitors GRCh38: Ensembl release 89: ENSG00000130234 - Ensembl, May 2017 GRCm38: Ensembl release ... Lazartigues E, Feng Y, Lavoie JL (2007). "The two fACEs of the tissue renin-angiotensin systems: implication in cardiovascular ...
*  Captopril suppression test
Aldosterone production is suppressed by captopril through the renin-angiotensin-aldosterone system. CST results are used to ...
*  Angiotensin II receptor type 1
Arima S, Ito S (Nov 2001). "New insights into actions of the renin-angiotensin system in the kidney: concentrating on the Ang ... Khoury NM, Marvar PJ, Gillespie CF, Wingo A, Schwartz A, Bradley B, Kramer M, Ressler KJ (Jun 2012). "The renin-angiotensin ... Padmanabhan N, Padmanabhan S, Connell JM (Dec 2000). "Genetic basis of cardiovascular disease--the renin-angiotensin- ... renal renin inhibition, renal tubular sodium reuptake, modulation of central sympathetic nervous system activity, cardiac ...
*  Angiotensin II receptor
Wright JW, Harding JW (September 2011). "Brain renin-angiotensin-a new look at an old system". Prog. Neurobiol. 95 (1): 49-67. ... They are important in the renin-angiotensin system: they are responsible for the signal transduction of the vasoconstricting ... renal renin inhibition, renal tubular sodium reuptake, modulation of central sympathetic nervous system activity, cardiac ...
*  Captopril challenge test
The CCT is considered positive if the renin levels increase substantially or the baseline renin level is abnormally high. An ... The captopril challenge test (CCT) is a non-invasive medical test that measures the change in renin plasma-levels in response ... Plasma concentration of renin is measured prior to and following the administration of captopril. ...
*  Renin inhibitor
... s bind to the active site of renin and inhibit the binding of renin to angiotensinogen, which is the rate- ... Brown, M. J. (2006). "Direct renin inhibition - a new way of targeting the renin system". Journal of Renin-Angiotensin- ... Consequently, renin inhibitors prevent the formation of Ang I and Ang II. Renin inhibitors may also prevent Ang-(1-7), Ang-(1-9 ... Renin is a circulating enzyme that acts on a circulating peptide, angiotensinogen. Renin cleaves the peptide at the Leu10-Val11 ...
*  Essential hypertension
Renin elevation is another risk factor. Renin is an enzyme secreted by the juxtaglomerular apparatus of the kidney and linked ... Vitamin D inhibits renin secretion and its activity, it therefore acts as a "negative endocrine regulator of the renin- ... High renin levels predispose to hypertension by causing sodium retention through the following mechanism: Increased renin → ... Low-renin hypertension is more common in African Americans than white Americans, and may explain why African Americans tend to ...
*  Angiotensin II receptor type 2
It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. ...
*  Renin
The normal concentration of renin in adult human plasma is 1.98-24.6 ng/L in the upright position. Renin activates the renin- ... Angiotensin-converting enzyme Plasma renin activity Renin inhibitor Renin stability regulatory element (REN-SRE) GRCh38: ... all of which may produce renin. Renin is usually measured as the plasma renin activity (PRA). PRA is measured specially in case ... Mature renin contains 340 amino acids and has a mass of 37 kDa. The enzyme renin is secreted by pericytes (mural cells) (1) in ...
*  Gamma-Renin
"Purification and properties of renin and γ-renin from the mouse submaxillary gland". J. Biol. Chem. 258: 2209-2216. PMID ... Gamma-renin (EC 3.4.21.54) is an enzyme. This enzyme catalyses the following chemical reaction Cleavage of the Leu-Leu bond in ... Gamma-renin at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and Cellular Biology portal. ... Drinkwater, C.C.; Evans, B.A.; Richards, R.I. (1988). "Sequence and expression of mouse γ-renin". J. Biol. Chem. 263: 8565-8568 ...
*  Renin-e Bozorg
... (Persian: رنين بزرگ‎, also Romanized as Renīn-e Bozorg; also known as Renīn-e Shams od Dīn) is a village in ... Renin-e Bozorg can be found at GEOnet Names Server, at this link, by opening the Advanced Search box, entering "10406724" in ...
*  Renin-angiotensin system
The renin-angiotensin system (RAS) or the renin-angiotensin-aldosterone system (RAAS) is a hormone system that regulates blood ... Direct renin inhibitors can also be used for hypertension. The drugs that inhibit renin are aliskiren and the investigational ... Nguyen, G (March 2011). "Renin, (pro)renin and receptor: an update". Clinical Science. 120 (5): 169-78. doi:10.1042/CS20100432 ... release the enzyme renin. Renin cleaves a decapeptide from angiotensinogen, a globular protein. The decapeptide is known as ...
*  Plasma renin activity
... (PRA), also known as the renin (active) assay or random plasma renin, is a measure of the activity of the ... Renin Direct. New Assays for Aldosterone, Renin and Parathyroid Hormone University of Washington, Department of Laboratory ... Cloning and sequence analysis of cDNA for human renin precursor. ; PubMed. Pivotal role of the renin/prorenin receptor in ... Different secretory pathways of renin from mouse cells transfected with the human renin gene. 1988 Mar 5; PubMed Free text. ...
*  Renin-e Kuchek
... can be found at GEOnet Names Server, at this link, by opening the Advanced Search box, entering "10406724" in ... Renin-e Kuchek (Persian: رنين كوچك‎, also Romanized as Renīn-e Kūcheḵ) is a village in Gowharan Rural District, Gowharan ...
*  Aldosterone-to-renin ratio
... (ARR) is the mass concentration of aldosterone divided by the plasma renin activity in blood plasma ... The aldosterone/renin ratio is recommended as screening tool for primary hyperaldosteronism. Aldosterone-to-renin ratio can be ... If the inverse ratio (i.e. renin-to-aldosterone) ratio is used, a value lower than the cutoff indicates primary ... Also, the inverse value is occasionally given, that is, the renin-to-aldosterone ratio, whose value is the multiplicative ...
*  Renin stability regulatory element (REN-SRE)
... of the renin (REN) gene. It acts to regulate the levels of renin protein produced in the cell. Renin is secreted by renal ... untranslated region of human renin mRNA and differentially modulate renin expression". J. Biol. Chem. 278 (45): 44894-903. doi: ... The Renin stability regulatory element (REN-SRE) is a cis-acting element identified in the 3'untranslated region (3'UTR) ... Page for Renin stability regulatory element (REN-SRE) at Rfam. ...
*  Journal of the Renin-Angiotensin-Aldosterone System
... is a peer-reviewed academic journal that publishes papers in the field of ... Journal of the Renin-Angiotensin-Aldosterone System is abstracted and indexed in, among other databases: SCOPUS, and the Social ... Journal of the Renin-Angiotensin-Aldosterone System is a resource for biomedical professionals, including basic scientists and ... Journal of the Renin-Angiotensin-Aldosterone System also publishes research on other peptides, such as vasopressin, the ...
*  List of cities, towns and villages in Hormozgan Province
Renin-e Bozorg , Renin-e Kuchek , Reza Alichi , Rezayi , Rezvan , Rig Deraz , Rig Kag , Rig Muled , Rig , Rig , Rigu , Rigu , ...
*  ACTH stimulation test
... low renin and low ACTH indicates atrophy of aldosterone production from the prolonged lack of renin. Similar to the cortisol ... "Aldosterone and Renin". L.A. Cunningham; M.A. Holzwarth (1988). "Vasoactive intestinal peptide stimulates adrenal aldosterone ... This factoring indicates secondary hypoaldosteronism (sodium low, potassium and renin enzyme will be low). Usually doubling to ... potassium and renin enzyme will be high) and is an indicator of primary adrenal insufficiency or Addison's disease. ...
*  Aliskiren
Renin, the first enzyme in the renin-angiotensin-aldosterone system, plays a role in blood pressure control. It cleaves ... Aliskiren (trade names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for ... Therefore, pharmacologists have been looking for a drug to inhibit renin directly. Aliskiren is the first drug to do so. "First ... Aliskiren binds to the S3bp binding site of renin, essential for its activity. Binding to this pocket prevents the conversion ...
*  Discovery and development of angiotensin receptor blockers
Blood pressure and fluid and electrolyte homeostasis is regulated by the renin-angiotensin-aldosterone-system. Renin, an enzyme ... Renin and Angiotensin; Jackson E.K., 789-821) Editors; Brunton L.L., Lazo J.S., Parker K.L. New York McGraw Hill 2006. ISBN 0- ... In 1939, renin was found not to cause the rise in blood pressure, but was an enzyme which catalyzed the formation of the ... Their results suggested the kidneys produced a protein, which they named renin, that caused a rise in blood pressure. In the ...
*  Rajko Igić
His research career centered on the [Renin Angiotensin System , renin-angiotensin system]. While at the University in Tuzla in ... Activity of renin and angiotensin converting enzyme in retina and ciliary body. (In Serbo-croatian). Liječ Vjes 1977;99:482-4. ... Igić R, Škrbić R. The renin-angiotensin system and its blockers. Srp Arh Celok Lek 2014;142:756-63. The Destiny of Germans in ... ISBN 978-99955-57-64-5 Farmakologija renin-angiotenzin sistema. Banja Luka, Medicinski fakultet, 2014. Igić R, Erdos EG, Yeh HS ...
*  ACE inhibitor
... also used to treat CHF Renin inhibitor Jackson, Edwin K. (2006). "Chapter 30. Renin and Angiotensin". In Brunton, Laurence L.; ... Renin activates a circulating liver derived prohormone angiotensinogen by proteolytic cleavage of all but its first ten amino ... Renin-angiotensin-aldosterone system is a major blood pressure regulating mechanism. Markers of electrolyte and water imbalance ... Luno J, Praga M, de Vinuesa SG (2005). "The reno-protective effect of the dual blockade of the renin angiotensin system (RAS ...
*  Valsartan
Renin and Angiotensin". In Brunton, L. L.; Chabner, Bruce; Knollmann, Björn C. Goodman & Gilman's The Pharmacological Basis of ... The packaging for valsartan includes a warning stating the drug should not be used with the renin inhibitor aliskiren in people ... Other inhibitors of the renin-angiotensin system may increase the risks of low blood pressure, kidney problems, and ...
*  Reabsorption
Renin-angiotensin system: 1. The kidneys sense low blood pressure. 2. Release renin into the blood. 3. Renin causes production ...