*Neurofibromin 1

"Analysis of NF1 transcriptional regulatory elements". American Journal of Medical Genetics. Part A. 137 (2): 130-5. doi:10.1002 ... Aberrant splicing may also occur due to mutations within a splicing regulatory element. Intronic mutations that fall outside of ... HuR binds to AU-rich elements which are scattered throughout the 3' UTR and are thought to be negative regulators of transcript ... A study conducted in 2000 examined whether the involvement of the 3' UTR in post-transcriptional gene regulation had an effect ...

*Gene

Maston, G. A.; Evans, S. K.; Green, M. R. (2006). "Transcriptional Regulatory Elements in the Human Genome". Annual Review of ... Regulatory regions can even be on entirely different chromosomes and operate in trans to allow regulatory regions on one ... with regulatory elements classified as gene-associated regions. In all organisms, two steps are required to read the ... For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into ...

*Gene structure

Maston, G. A.; Evans, S. K.; Green, M. R. (2006). "Transcriptional Regulatory Elements in the Human Genome". Annual Review of ... Maston, Glenn A.; Evans, Sara K.; Green, Michael R. (2006). "Transcriptional Regulatory Elements in the Human Genome". Annual ... Regulatory elements can overlap one another, with a section of DNA able to interact with many competing activators and ... For genes with multiple regulatory sequences, the rate of transcription is the product of all of the elements combined. Binding ...

*Enhancer (genetics)

Maston, G. A.; Evans, S. K.; Green, M. R. (2006). "Transcriptional Regulatory Elements in the Human Genome". Annual Review of ... Maston, Glenn A.; Evans, Sara K.; Green, Michael R. (2006-01-01). "Transcriptional Regulatory Elements in the Human Genome". ... S. "Identifying transcriptional cis ‐regulatory modules in animal genomes". WIREs Dev Biol. 4 (2014): 59-84. doi:10.1002/wdev. ... 2011). "Nodal cis-regulatory elements reveal epiblast and primitive endoderm heterogeneity in the peri-implantation mouse ...

*Noncoding DNA

Maston, Glenn; Sarah Evans; Michael Green (23 May 2006). "Transcriptional regulatory elements in the Human Genome" (PDF). ... Cis-regulatory elements are sequences that control the transcription of a nearby gene. Many such elements are involved in the ... Cis-elements may be located in 5' or 3' untranslated regions or within introns. Trans-regulatory elements control the ... Stojic, L. "Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related ...

*Silencer (genetics)

Maston, Glenn; Sarah Evans; Michael Green (23 May 2006). "Transcriptional regulatory elements in the Human Genome" (PDF). ... which are the classical silencer element and the non-classical negative regulatory element (NRE). In classical silencers, the ... Another regulatory element located upstream of the gene is an enhancer. Enhancers function as a "turn on" switch in gene ... Though these two regulatory elements work against each other, both sequence types affect the promoter region in very similar ...

*ChIA-PET

Maston et al., (2006). Transcriptional Regulatory Elements in the Human Genome. Annu. Rev: Genomics. Hum Genet. (7); 29-59. ... Figure 7. Proposed mechanism showing how distal regulatory elements can initiate long-range chromatin interactions involving ... insulators and boundary elements, and transcription-factor binding sites (TFBS). Uncovering the interplay between regulatory ... which could increase the local concentration of regulatory proteins for enhanced transcriptional activation. This mechanism ...

*Regulator gene

"Discovery and Characterization of Human Exonic Transcriptional Regulatory Elements". PLoS ONE. 7 (9). doi:10.1371/journal.pone. ... Insulators, also called boundary elements, are DNA sequences that create cis-regulatory boundaries that prevent the regulatory ... Ahituv, Nadav (2012). "Gene Regulatory Elements" (PDF). Gene Regulatory Sequences and Human Disease (2012). doi:10.1007/978-1- ... Positive regulators are regulatory elements that permit RNA polymerase binding to the promoter region, thus allowing ...

*REDfly

The REDfly is database of transcriptional cis-regulatory elements for Drosophila Transcriptional regulation transcription ... toward a comprehensive database of transcriptional regulatory elements in Drosophila". Nucleic Acids Res. England. 39 (Database ...

*Sterol regulatory element-binding protein 2

"Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2". The Journal of Biological ... Sterol regulatory element-binding protein 2 (SREBP-2) also known as sterol regulatory element binding transcription factor 2 ( ... Kotzka J, Müller-Wieland D, Roth G, Kremer L, Munck M, Schürmann S, Knebel B, Krone W (Jan 2000). "Sterol regulatory element ... Hua X, Wu J, Goldstein JL, Brown MS, Hobbs HH (Feb 1995). "Structure of the human gene encoding sterol regulatory element ...

*Hepatitis B virus

Smith GJ, Donello JE, Lück R, Steger G, Hope TJ (1998). "The hepatitis B virus post-transcriptional regulatory element contains ... "Solution structure of stem-loop alpha of the hepatitis B virus post-transcriptional regulatory element". Nucleic Acids Research ... but some evidence suggests that it may function as a transcriptional transactivator. Several non-coding RNA elements have been ...

*Hepatitis B virus PRE alpha

"The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for ... "Solution structure of stem-loop alpha of the hepatitis B virus post-transcriptional regulatory element". Nucleic Acids Research ... key parts of the HBV post-transcriptional regulatory element". RNA biology. 13 (9): 743-7. doi:10.1080/15476286.2016.1166330. ... Lim, CS; Brown, CM (September 2016). "Hepatitis B virus nuclear export elements: RNA stem-loop α and β, ...

*CLIPZ

... is a database of post-transcriptional regulatory elements (RNA-binding proteins) built from cross-linking and ...

*Avian HBV RNA encapsidation signal epsilon

Smith Gj, 3rd; Donello, JE; Lück, R; Steger, G; Hope, TJ (1998). "The hepatitis B virus post-transcriptional regulatory element ... It includes the major elements shown in Figures 1 and 2. HBV RNA encapsidation signal epsilon Schmid, B; Rösler, C; Nassal, M ( ... best discriminates between the true instances of the element in sequence databases and background. The secondary structure ...

*Hepatitis B virus PRE beta

"The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for ... Chen, A; Panjaworayan T-Thienprasert, N; Brown, CM (7 July 2014). "Prospects for inhibiting the post-transcriptional regulation ...

*CYP3A7

"Two linked mutations in transcriptional regulatory elements of the CYP3A5 gene constitute the major genetic determinant of ...

*ACTA2

1991). "Transcriptional regulatory elements in the 5' upstream and first intron regions of the human smooth muscle (aortic type ... 1998). "Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein". Oncogene. 16 (10 ...

*DNA polymerase beta

"Hairpin structure within the 3'UTR of DNA polymerase beta mRNA acts as a post-transcriptional regulatory element and interacts ... it was shown that this stem loop structure acts as a RNA destabilizing element. In addition to these cis-regulatory elements ... Rfam entry for the stem loopII (M2) regulatory element in POLB. ... gene expression is also regulated at the post transcriptional ... POLB gene is upregulated by CREB1 transcription factor's binding to the cAMP response element(CRE) present in the promoter of ...

*Sterol regulatory element-binding protein 1

... and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1)". The Journal of Biological ... Sterol regulatory element-binding transcription factor 1 (SREBF1) also known as sterol regulatory element-binding protein 1 ( ... Kotzka J, Müller-Wieland D (Apr 2004). "Sterol regulatory element-binding protein (SREBP)-1: gene regulatory target for insulin ... called sterol regulatory element-1 (SRE1). This element is a decamer flanking the LDL receptor gene and other genes involved in ...

*Hepatitis B virus PRE 1151-1410

"A conserved RNA structural element within the hepatitis B virus post-transcriptional regulatory element enhance nuclear export ... Hepatitis B virus PRE 1151-1410 (HBV post-transcriptional regulatory element, nucleotides 1151-1410) is a part of 500 base pair ... Hence it was proposed to be the core HBV PRE element. PRE1151-1410 contains 3 known regulatory elements: PRE SL-alpha ( ... However, the function is controversial and new regulatory elements have been predicted within PRE. PRE 1151-1410 enhances ...

*Lipogenesis

"Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level". The Journal of Biological ... Foretz, M.; Guichard, C.; Ferré, P.; Foufelle, F. (1999-10-26). "Sterol regulatory element binding protein-1c is a major ... "Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes ... "Sterol regulatory element-binding proteins: activators of cholesterol and fatty acid biosynthesis". Current Opinion in ...

*Epstein-Barr virus nuclear antigen 2

EBNA-LP stimulates EBNA2 activation of the LMP1 promoter and of the LMP1/LMP2B bidirectional transcriptional regulatory element ... Specific responsive elements that share the core sequence GTGGGAA have been discovered in several of the promoters activated by ... EBNA2 requires C-promoter binding factor 1 (CBF1) to aid in binding to its cis-responsive DNA element, the C promoter (Cp). ... Additionally, EBNA2 interacts with an EBNA2 responsive cis-element of the TP1 promoter. Interactions with both the TP1 and LMP/ ...

*NKRF (gene)

This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate ... transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a ... 2007). "NRF IRES activity is mediated by RNA binding protein JKTBP1 and a 14-nt RNA element". RNA. 13 (8): 1328-40. doi:10.1261 ... 2002). "Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: The role ...

*Promoter (genetics)

... are typically located upstream of the gene and can have regulatory elements several kilobases away from the transcriptional ... The TATA element and BRE typically are located close to the transcriptional start site (typically within 30 to 40 base pairs). ... Promoters represent critical elements that can work in concert with other regulatory regions (enhancers, silencers, boundary ... The sequence at -10 (the -10 element) has the consensus sequence TATAAT. The sequence at -35 (the -35 element) has the ...

*FLP-FRT recombination

cis-regulatory elements play a major role in the transcriptional activation of genes in plants, and many are not well ... one base pair away from the upstream element and in the same orientation: 5'GAAGTTCCTATTCcGAAGTTCCTATTCtctagaaaGtATAGGAACTTC3' ...

*Interferon

Binding of ISGF3 and other transcriptional complexes activated by IFN signaling to these specific regulatory elements induces ... elements in gene promoters. Type I IFNs can induce expression of genes with either ISRE or GAS elements, but gene induction by ... Inside the nucleus, the ISGF3 complex binds to specific nucleotide sequences called IFN-stimulated response elements (ISREs) in ... type II IFN can occur only in the presence of a GAS element. In addition to the JAK-STAT pathway, IFNs can activate several ...