Loading...
*  Biochemical cascade
There are two main types of purinergic receptors, P1 binding to adenosine, and P2 binding to ATP or ADP, presenting different ... Therefore, there are four main transmembrane receptor types: G protein coupled receptors (GPCRs), tyrosine kinase receptors ( ... PAR1 and PAR4 receptors), platelet-derived thromboxane A2 (TxA2) (TP receptor) and ADP (P2Y1 and P2Y12 receptors) that is ... Adenosine acts by binding to purinergic receptors and influencing adenilyl cyclase activity and the formation of cAMP and PKA ...
*  Purinergic signalling
There are three known distinct classes of purinergic receptors, known as P1, P2X, and P2Y receptors. Cell signalling events ... The purinergic signalling complex of a cell is sometimes referred to as the "purinome". Purinergic receptors, represented by ... Purinergic receptors are specific classes of membrane receptors that mediate various physiological functions such as the ... There are currently four types of adenosine receptors found in the heart. After binding onto a specific purinergic receptor, ...
*  Adenosine receptor
The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ... The adenosine A1 receptor has been found to be ubiquitous throughout the entire body. This receptor has an inhibitory function ... Adenosine receptors play a key role in the homeostasis of bone. The A1 receptor has been shown to stimulate osteoclast ... Similarly to A2A receptor, the A2B receptor promotes osteoblast differentiation. The osteoblast cell is derived from the ...
*  P2 receptor
... may refer to: P2Y receptors P2X receptors P is for purinergic, P2 refers to ATP receptors, as opposed to P1 ... P2X receptors are ATP activated channels that allows the passage of ions across cell membranes. P2Y receptors are ATP activated ... G protein-coupled receptors (GPCRs) that initiate an intracellular chain of reactions.. ...
*  Rostral ventromedial medulla
Histological staining by another research group examined the distribution of purinergic receptor subtypes throughout the RVM. ... a large majority were co-labeled with purinergic antibodies. Fifty-five percent of TPH+ neurons stained for P1, 63% for P2X1, ... Close, L.N. (January 2009). "Purinergic Receptor Immunoreactivity in the Rostral Ventromedial Medulla". Neuroscience. 158 (2): ... NK1 agonism induced hypersensitivity is dependent on 5-HT3 receptors, and modulated by GABAA and NMDA receptors as well. ...
*  Index of biochemistry articles
... purinergic P1 receptor - purinergic P2 receptor - purinergic receptor - pyridine - pyrimidine - pyruvate - pyruvate oxidation ... interleukin receptor - interleukin-1 receptor - interleukin-2 receptor - interleukin-3 - interleukin-3 receptor - intermediate ... G protein-coupled receptor - G3P - GABA - GABA receptor - GABA-A receptor - gag-onc fusion protein - galanin - gamete - gamma- ... IgE receptor - IGF type 1 receptor - IGF type 2 receptor - IgG - IgM - immediate-early protein - immune cell - immune system - ...
*  ENTPD1
Kukulski F, Lévesque SA, Sévigny J (2011-01-01). "Impact of ectoenzymes on p2 and p1 receptor signaling". Advances in ... "Comparative hydrolysis of P2 receptor agonists by NTPDases 1, 2, 3 and 8". Purinergic Signalling. 1 (2): 193-204. doi:10.1007/ ... For example, NTPDase1 hydrolyzes P2 receptor ligands, namely ATP, ADP, UTP and UDP with similar efficacy. NTPDase1 can ... Yegutkin GG (May 2008). "Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling ...
*  Damage-associated molecular pattern
Similarly, adenosine triggers degranulation through P1 receptors. Uric acid is also an endogenous danger signal released by ... that have reached the extracellular space can also serve as danger signals by signaling through purinergic receptors. ATP and ... Known receptors for HMGB1 include TLR2, TLR4 and RAGE (receptor for advanced glycation endproducts). HMGB1 can induce dendritic ... Extracellular ATP triggers mast cell degranulation by signaling through P2X7 receptors. ...
*  List of MeSH codes (D12.776.543)
... receptor, par-1 MeSH D12.776.543.750.810.150 -- receptors, cyclic amp MeSH D12.776.543.750.810.700 -- receptors, purinergic p1 ... receptors, cyclic amp MeSH D12.776.543.750.100.700.700 -- receptors, purinergic p1 MeSH D12.776.543.750.100.700.700.100 -- ... receptors, cyclic amp MeSH D12.776.543.750.720.700.700 -- receptors, purinergic p1 MeSH D12.776.543.750.720.700.700.100 -- ... receptor, adenosine a3 MeSH D12.776.543.750.720.700.720 -- receptors, purinergic p2 MeSH D12.776.543.750.725.500 -- receptor, ...
*  Purinergic receptor
There are three known distinct classes of purinergic receptors, known as P1, P2X, and P2Y receptors. P2X receptors are ligand- ... P1 receptors are preferentially activated by adenosine and P2Y receptors are preferentially more activated by ATP. P1 and P2Y ... IUPHAR GPCR Database - Adenosine receptors IUPHAR GPCR Database - P2Y receptors Purinergic Receptors at the US National Library ... P2 receptors) or adenosine (P1 receptors). P2 receptors have further been divided into five subclasses: P2X, P2Y, P2Z, P2U, and ...
*  Astrocyte
... and neurokinin 1 receptor (NK1R), as well as activation of metabotropic glutamate receptors and release of BDNF. Persistent ... The resultant patterning along the neuraxis leads to segmentation of the neuroepithelium into progenitor domains (p0, p1 p2, p3 ... "Astrocytic purinergic signaling coordinates synaptic networks". Science. 310 (5745): 113-6. doi:10.1126/science.1116916. PMID ... and kainate subtypes of ionotropic glutamate receptors follows. It is the activation of these receptors that potentiates the ...