Karlov D, Barygin O, Dron M, Palyulin V, Grigoriev V, Fedorov M (2019). "Short peptide with an inhibitory activity on the NMDA/ ... The NMDA receptor is an ionotropic receptor that allows for the transfer of electrical signals between neurons in the brain and ... Most NMDA receptor antagonists are metabolized in the liver. Frequent administration of most NMDA receptor antagonists can lead ... Since NMDA receptor overactivation is implicated in excitotoxicity, NMDA receptor antagonists have held much promise for the ...

These antidepressant effects have been linked to endogenous opioid peptides acting at ∆- and μ-opioid receptors, and so can ... The ∆-opioid receptor, also known as delta opioid receptor or simply delta receptor, abbreviated DOR or DOP, is an inhibitory 7 ... Portoghese PS, Sultana M, Takemori AE (Jan 1988). "Naltrindole, a highly selective and potent non-peptide delta opioid receptor ... However, there are now several selective ∆-opioid receptor agonists available, including peptides such as DPDPE and deltorphin ...

Watson, C. S. (1999). "Signaling Themes Shared Between Peptide and Steroid Hormones at the Plasma Membrane". Science Signaling ... Membrane steroid receptors (mSRs), also called extranuclear steroid receptors, are a class of cell surface receptors activated ... Cav1.2 Membrane corticosteroid receptors Membrane glucocorticoid receptors (mGRs) - caveolin-associated nuclear receptors; ... Known groups of mSRs, by ligand, include: Membrane sex steroid receptors Membrane estrogen receptors (mERs) - GPER, ER-X, ERx, ...

... which it achieved by activating the synthesis of antimicrobial peptides. The first reported human toll-like receptor was ... NOD-like receptor Immunologic adjuvant RIG-I-like receptor Toll-Like+Receptors at the U.S. National Library of Medicine Medical ... TLRs together with the Interleukin-1 receptors form a receptor superfamily, known as the "interleukin-1 receptor / toll-like ... Toll-like receptors and ligands database at University of Munich The Toll-Like Receptor Family of Innate Immune Receptors (pdf ...

They are also referred to as μ(mu)-opioid peptide (MOP) receptors. The prototypical μ-opioid receptor agonist is morphine, the ... The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low ... "Opioid Receptors: μ". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. mu ... δ-opioid receptor κ-opioid receptor GRCh38: Ensembl release 89: ENSG00000112038 - Ensembl, May 2017 GRCm38: Ensembl release 89 ...

"Secretin and vasoactive intestinal peptide receptors: members of a unique family of G protein-coupled receptors". ... The secretin receptor has been shown to interact with pituitary adenylate cyclase activating peptide. GRCh38: Ensembl release ... The secretin receptor is a protein that in humans is encoded by the SCTR gene. This protein is a G protein-coupled receptor ... IUPHAR GPCR Database - Secretin receptor secretin+receptor at the U.S. National Library of Medicine Medical Subject Headings ( ...

... is a peptide toxin from the venom of the scorpion Hadrurus gertschi. Hadrucalcin modifies the Ryanodine receptor ... Hadrucalcin is a peptide toxin from the scorpion calcin family. The mature hadrucalcin peptide is composed of 35 amino acids, ... a peptide from Hadrurus gertschi scorpion venom with pharmacological activity on ryanodine receptors. Br J Pharmacol. 2009;157( ... Hadrucalcin targets ryanodine receptor channels RyR1 and RyR2, found in the sarcoplasmic reticulum of skeletal muscle cells and ...

... Receptor-A (NPR-A), Natriuretic Peptide Receptor-B (NPR-B), and Natriuretic Peptide Receptor-C (NPR-C). NPR ... There are three main types of natriuretic peptides: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C- ... Natriuretic peptides and their receptors have many different effects on the body, such as controlling blood pressure and ... Each peptide has its own unique effects and interacts with specific receptors. Scientists have observed these effects by ...

2002). "Characterization of calcitonin gene-related peptide (CGRP) receptors and their receptor-activity-modifying proteins ( ... "Entrez Gene: RCP9 calcitonin gene-related peptide-receptor component protein". Yallampalli C, Chauhan M, Thota CS, et al. (2003 ... 2003). "Investigation of CGRP receptors and peptide pharmacology in human coronary arteries. Characterization with a nonpeptide ... "Calcitonin gene-related peptide in pregnancy and its emerging receptor heterogeneity". Trends Endocrinol. Metab. 13 (6): 263-9 ...

Cody WL, Doherty AM (1995-01-01). "The development of potent peptide agonists and antagonists for the endothelin receptors". ... and endothelin receptor type B (ETB). These receptors are G-protein-coupled receptors. ETB receptors bind ETs and SRTXs with ... Davenport AP, Hoskins SL, Kuc RE, Plumpton C (November 1996). "Differential distribution of endothelin peptides and receptors ... In the case of ET/SRTX binding to a receptor and creation of a receptor-ligand complexes in various tissues, a very slow pace ...

2003). "Expression of prolactin-releasing peptide and its receptor in the human adrenal glands and tumor tissues of ... Prolactin-releasing peptide (PrRP) is a peptide hormone that in humans is encoded by the PRLH gene. PrRP stimulates prolactin ( ... 1999). "Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor". Regul. Pept. 83 (1): 1-10. doi:10.1016/ ... 2000). "Expression of prolactin-releasing peptide and its receptor messenger ribonucleic acid in normal human pituitary and ...

... receptor (MCHR) Melanin-concentrating hormone receptor 1 (MCHR1) Melanin-concentrating hormone ... Peptides. 30 (11): 2031-9. doi:10.1016/j.peptides.2009.05.028. PMID 19524001. S2CID 25313032. Naufahu J, Cunliffe AD, Murray JF ... Peptides. 30 (11): 2071-5. doi:10.1016/j.peptides.2009.04.025. PMID 19442695. S2CID 10189765. Melanin-concentrating+hormone at ... MCH is activated by binding to two G-coupled protein receptors (GCPRs), MCHR1 and MCHR2. MCHR2 has only been identified in ...

"Stimulation of endothelial cell prostaglandin production by angiotensin peptides. Characterization of receptors". Hypertension ... Effects of angiotensin converting enzyme inhibition and angiotensin II type 1 receptor blockade". Basic Research in Cardiology ...

Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B), also known as NPR2, is an atrial ... "Entrez Gene: NPR2 natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)". Tsuji T, Kunieda T ... "C-type natriuretic peptide and guanylyl cyclase B receptor". Peptides. 26 (6): 1024-34. doi:10.1016/j.peptides.2004.08.027. ... "Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B ...

Pogo AO, Chaudhuri A (1996). "Duffy and receptors for P. vivax and chemotactic peptides". Transfusion Clinique et Biologique. 2 ... Duffy Antigen Receptor for Chemokines). The chemokine binding site on the receptor appears to be localised to the amino ... The Duffy antigen has been found to act as a multispecific receptor for chemokines of both the C-C and C-X-C families, ... Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234), is a ...

Each receptor demonstrates a specific affinity for either neurokinin A or substance P peptides. Both peptides, however, can act ... most notably through the receptor NK2, though regulation of NK2 receptors seems to be mediated by the activity of NK1 receptors ... Regoli D, Boudon A, Fauchére J (1994). "Receptors and antagonists for substance P and related peptides". Pharmacol Rev. 46 (4 ... Journal Maggi C, Patacchini R, Rovero P, Giachetti A (1993). "Tachykinin receptors and tachykinin receptor antagonists". ...

They are calcitonin gene-related peptide (CGRP) receptor antagonists. Gepants have been suggested to have less pain relief at 2 ... and Calcitonin-Gene-Related Peptide (CGRP) Receptor Monoclonal Antibodies". Pharmaceutics. 12 (12): 1180. doi:10.3390/ ... It is theorized that by antagonizing the CGRP receptor of the trigeminal ganglia, lowered CGRP is released and less migraine ... These medications are selective 5-HT1B/1D receptor agonists with some activity at 5-HT1F. They produce an antimigraine effect ...

Steckelings, U; Kaschina, E; Unger, T (2005). "The AT2 receptor-A matter of love and hate". Peptides. 26 (8): 1401-9. doi: ... Peptides. 26 (11): 2274-9. doi:10.1016/j.peptides.2005.04.025. PMID 16137788. "Master Journal List". Intellectual Property & ... "Differential BBB interactions of three ingestive peptides: Obestatin, ghrelin, and adiponectin". Peptides. 27 (4): 911-6. doi: ... "Peptides". 2020 Journal Citation Reports. Web of Science (Science ed.). Thomson Reuters. 2021. Official website (Articles with ...

... like receptor/receptor activity modifying protein complexes define calcitonin gene-related peptide and adrenomedullin receptors ... Calcitonin receptor-like (CALCRL), also known as the calcitonin receptor-like receptor (CRLR), is a human protein; it is a ... 2002). "Expression and distribution of calcitonin receptor-like receptor in human hairy skin". Peptides. 23 (1): 109-16. doi: ... Sams A, Jansen-Olesen I (1999). "Expression of calcitonin receptor-like receptor and receptor-activity-modifying proteins in ...

... is a calcitonin gene-related peptide receptor antagonist. It is sprayed into the nose. It is sold by Pfizer. The ... Calcitonin gene-related peptide receptor antagonists, Pfizer brands, Piperazines, Piperidines, Indazoles, Quinolines, Ureas, ...

"Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type ... "C-type natriuretic peptide and guanylyl cyclase B receptor". Peptides. 26 (6): 1024-34. doi:10.1016/j.peptides.2004.08.027. ... The precursor NPPC protein is cleaved to the 22 amino acid peptide C-type natriuretic peptide (CNP). Natriuretic peptides ... "Differential gene expression of the three natriuretic peptides and natriuretic peptide receptor subtypes in human liver". Gut. ...

Pardridge, W.M. (1986). "Receptor-mediated peptide transport through the blood-brain barrier". Endocrine Reviews. 7 (3): 314- ... Transcytosis can be receptor-mediated and consists of three steps: 1) receptor-mediated endocytosis of the molecule on one side ... undergoes RMT across the BBB via transport on brain endothelial receptors such as the insulin receptor or transferrin receptor ... Receptor-mediated transcytosis, or RMT, across the BBB is a potential pathway for drug delivery to the brain, particularly for ...

... is a protein/peptide-antigen receptor and graft-versus-host disease antigen that is composed of 2 subunits, DPα and DPβ ... class II receptor/antigens to a great many T-cells, each with unique T-cell receptor (TCR) variants. A few TCR variants that ... HLA-DP is an αβ-heterodimer cell-surface receptor. Each DP subunit (α-subunit, β-subunit) is composed of a α-helical N-terminal ... The α-helical domain forms the sides of the peptide binding groove. The β-sheet regions form the base of the binding groove and ...

Battey J, Wada E (1991). "Two distinct receptor subtypes for mammalian bombesin-like peptides". Trends Neurosci. 14 (12): 524- ... The final peptides are eight to fourteen residues long. Erspamer V, Erspamer GF, Mazzanti G, Endean R (1984). "Active peptides ... Bombesin-like peptides comprise a large family of peptides which were initially isolated from amphibian skin, where they ... Bombesin-like peptides, like many other active peptides, are synthesized as larger protein precursors that are enzymatically ...

"Evidence for stanniocalcin and a related receptor in annelids". Peptides. 25 (10): 1671-1679. doi:10.1016/j.peptides.2004.02. ... The peptide sequence is characterised by the presence of 11 half-Cys residues and one N-linked glycosylation site. The actual ... Stanniocalcin is a glycoprotein that exists in a homodimer, i.e. two similar peptide molecules combined. Each single molecule ... In breast cancer the elevated hormones correspond to increased estrogen receptors. Increased STC1 is specifically linked to ...

Peptide signaling plays a significant role in various aspects of plant growth and development and specific receptors for ... Studies suggest that the HAESA membrane-associated LRR-RLK is likely to be this peptide's receptor as it too is expressed in ... It has been demonstrated that PSK binds to a membrane bound LRR receptor like kinase (PSKR). POLARIS (PLS) - The PLS peptide ... SCR/SP11 like other small peptide hormones binds to a membrane bound LRR receptor like kinase (SRK). ROTUNDIFOLIA4/DEVIL1 (ROT4 ...

During graduate school, Yapici was a member of the group that was the first to characterize the Drosophila sex peptide receptor ... During this time, Yapici helped to discover the receptor for sex peptide. In 2009, Yapici completed her graduate training and ... MIPs are ancestral ligands for the sex peptide receptor. Proceedings of the National Academy of Sciences U.S.A., 107, 6520-6525 ... "MIPs are ancestral ligands for the sex peptide receptor". Proceedings of the National Academy of Sciences of the United States ...

... is an experimental peptide drug derived from vasoactive intestinal peptide (VIP) that can change the behavior of ... LBT-3627 specifically targets the VIP2 receptor, unlike VIP. The drug also affects microglia. In addition, LBT-3627 is more ... "Research programme: peptide-based therapeutics - Longevity Biotech". AdisInsight. January 8, 2018. Highest Development Phases: ... Preclinical : Neurological disorders; Type 2 diabetes mellitus (Antiparkinsonian agents, Peptides, Receptor agonists). ...

Melanocortin receptor agonists, Peptide hormones, All stub articles, Biochemistry stubs). ... Peptides. 32 (5): 1068-1072. doi:10.1016/j.peptides.2011.02.006. PMC 3112371. PMID 21335042. Reudelhuber TL (April 2003). "Salt ... ISBN 978-0-12-385096-6. Jakubke HD, Sewald N (8 September 2008). Peptides from A to Z: A Concise Encyclopedia. John Wiley & ... γ-Melanocyte-stimulating hormone (γ-MSH) is an endogenous peptide hormone and neuropeptide. It is a melanocortin, specifically ...

Yamaguchi Y, Huffaker A, Bryan AC, Tax FE, Ryan CA (February 2010). "PEPR2 is a second receptor for the Pep1 and Pep2 peptides ... Yamaguchi Y, Pearce G, Ryan CA (June 2006). "The cell surface leucine-rich repeat receptor for AtPep1, an endogenous peptide ... PEPR 1 is a receptor kinase with extra cellular leucine rich repeat motif and functions as a receptor for AtPEPs. In addition, ... Plant membrane PRR mainly consist of receptor like kinases and receptor like proteins. They sense PAMPs such as chitin from ...

The angiotensin receptor is activated by the vasoconstricting peptide angiotensin II. The activated receptor in turn couples to ... Angiotensin II receptor type 1 (AT1) is the best characterized angiotensin receptor. It is encoded in humans by the AGTR1 gene ... "Angiotensin Receptors: AT1". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical ... Due to the hemodynamic pressure and volume effects mediated by AT1 receptors, AT1 receptor antagonists are widely prescribed ...

Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci ... Interleukin 21 receptor is a type I cytokine receptor. IL21R is its human gene. The protein encoded by this gene is a cytokine ... 2005). "Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity". Mol. Cell ... 2000). "Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain". Proc. Natl. Acad. Sci. U.S.A. 97 ( ...

... neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type ... Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on ... The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for ... Interleukin 8 receptor, alpha Interleukin 8 Interleukin Interleukin receptor Cluster of differentiation G protein-coupled ...

Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci ... Decoy receptor 2 (DCR2), also known as TRAIL receptor 4 (TRAILR4) and tumor necrosis factor receptor superfamily member 10D ( ... The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL- ... This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. GRCh38 ...

Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". ... Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this ... "Entrez Gene: FGFRL1 fibroblast growth factor receptor-like 1". Liu C, Gao J, Cui X, Li Z, Chen L, Yuan Y, et al. (March 2021 ... Kim I, Moon S, Yu K, Kim U, Koh GY (March 2001). "A novel fibroblast growth factor receptor-5 preferentially expressed in the ...

June 2009). "Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ". Proceedings of the ... These are G-protein-coupled receptors, which are often referred to as pheromone receptors since vomeronasal receptors have been ... Recent studies proved a new family of formyl peptide receptor like proteins in VNO membranes of mice, which points to a close ... Rivière S, Challet L, Fluegge D, Spehr M, Rodriguez I (May 2009). "Formyl peptide receptor-like proteins are a novel family of ...

... structural basis for peptide selection by receptors involved in nitrogen uptake; structural basis for vitamin recognition and ... "The structural basis for peptide selection by the transport receptor OppA". The EMBO Journal. EMBO Press. 28 (9): 1332-1340. ...

... a family of receptors belonging to class A G-protein coupled receptors and they are activated by the closely related peptide ... "Neuropeptide Y Receptors". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical ... There are five known mammalian neuropeptide Y receptors designated Y1 through Y5. Four neuropeptide Y receptors each encoded by ... G protein-coupled receptors, All stub articles, Transmembrane receptor stubs). ...

Rivière S, Challet L, Fluegge D, Spehr M, Rodriguez I (May 2009). "Formyl peptide receptor-like proteins are a novel family of ... Adrenergic receptor Olfactory receptors Receptor tyrosine kinases Epidermal growth factor receptor Insulin Receptor Fibroblast ... Cell surface receptors (membrane receptors, transmembrane receptors) are receptors that are embedded in the plasma membrane of ... Integrins Low Affinity Nerve Growth Factor Receptor NMDA receptor Several Immune receptors Toll-like receptor T cell receptor ...

Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". ... Ectodysplasin A receptor (EDAR) is a protein that in humans is encoded by the EDAR gene. EDAR is a cell surface receptor for ... Ectodysplasin A2 receptor Monreal AW, Ferguson BM, Headon DJ, Street SL, Overbeek PA, Zonana J (August 1999). "Mutations in the ... It is structurally related to members of the TNF receptor superfamily. EDAR and other genes provide instructions for making ...

"Evidence for an endogenous peptide ligand and antagonist for PCP receptors". Prog. Clin. Biol. Res. 192: 495-8. PMID 3001770. ... α-Endopsychosin is an antagonist of the phencyclidine site of the NMDA receptor which was discovered in extracts of porcine ... The compound appears to be a peptide, but has yet to be purified and fully characterized. N,N-Dimethyltryptamine N- ... NMDA receptor antagonists, All stub articles, Biochemistry stubs). ...

... receptor Carraway R, Leeman SE (1973). "The isolation of a new hypotensive peptide, neurotensin, from bovine ... These large peptides appear to be less potent than their smaller counterparts, but are also less sensitive to degradation and ... While neurotensin receptor 1 (Ntsr1) mRNA in the paraventricular nucleus of the hypothalamus (PVN) was lowered, neurotensin, ... DNA promoter methylation has been shown to be a major regulator in the expression of neurotensin receptor 1 and 2 genes in ...

A synthetic SFLLRN peptide has been found to serve as an agonist for PAR1. The SFLLRN peptide mimics the first six residues of ... Proteinase-activated receptor 1 (PAR1) also known as protease-activated receptor 1 or coagulation factor II (thrombin) receptor ... Hoffman M, Church FC (August 1993). "Response of blood leukocytes to thrombin receptor peptides". Journal of Leukocyte Biology ... March 1994). "Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and ...

Leung, L. L.; Li, W. X.; McGregor, J. L.; Albrecht, G.; Howard, R. J. (5 September 1992). "CD36 peptides enhance or inhibit ... A two-step process of ligand-receptor interaction". Journal of Biological Chemistry. 267 (25): 18244-18250. doi:10.1016/S0021- ... a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes". Cell. 82 (1): 77-87. doi: ... "Involvement of CD36 on erythrocytes as a rosetting receptor for Plasmodium falciparum-infected erythrocytes". Blood. 80 (8): ...

Lipkowski AW, Tam SW, Portoghese PS (July 1986). "Peptides as receptor selectivity modulators of opiate pharmacophores". ... Since peptide compounds are unable to cross the blood-brain barrier, researchers developed naltrindole to be a non-peptide ... a highly selective and potent non-peptide delta opioid receptor antagonist". European Journal of Pharmacology. 146 (1): 185-6. ... Granier S, Manglik A, Kruse AC, Kobilka TS, Thian FS, Weis WI, Kobilka BK (May 2012). "Structure of the δ-opioid receptor bound ...

... but its effect is primarily on neuronal receptors rather than muscular nicotinic receptors. Conversely, β- and γ-bungarotoxins ... Pharmacology and Therapeutic Potential of Venom Peptides. 181: 114168. doi:10.1016/j.bcp.2020.114168. ISSN 0006-2952. PMID ... They discovered that this venom consisted of a mixture of individual toxins that act at different sites and receptors to ... In actuality, venom contains several distinct bungarotoxins, each varying in which receptors they act on and how powerful they ...

Scott V, Kimura N, Stark JA, Luckman SM (July 2005). "Intravenous peptide YY3-36 and Y2 receptor antagonism in the rat: effects ... "Anxiolytic-like effect of the selective neuropeptide Y Y2 receptor antagonist BIIE0246 in the elevated plus-maze". Peptides. 27 ... 12): 3202-7. doi:10.1016/j.peptides.2006.07.020. PMID 16959374. Félétou M, Levens NR (October 2005). "Neuropeptide Y2 receptors ... BIIE-0246 is a drug used in scientific research which acts as a potent and selective antagonist for the Neuropeptide Y receptor ...

... is a synthetic peptide and GnRH analogue. It is used as the acetate salt. Gonadotropin-releasing hormone receptor § ... Peptides, Veterinary drugs, All stub articles, Genito-urinary system drug stubs). ...

Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A), also known as NPR1, is an atrial ... "Entrez Gene: NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)". BioGPS > NPR1 ... Garg R, Pandey KN (2005). "Regulation of guanylyl cyclase/natriuretic peptide receptor-A gene expression". Peptides. 26 (6): ... Pandey KN (2005). "Internalization and trafficking of guanylyl cyclase/natriuretic peptide receptor-A". Peptides. 26 (6): 985- ...

The receptor is called the gastrin-releasing peptide (GRP) receptor. This receptor is stress-vulnerable and should be targeted ... Breedlove helped to find the receptor that is affected by the PTSD. This was found through a series of stress tests on rats. ... Once the GRP was stimulated in the male rats, androgen receptors worked, and erectile dysfunction was cured. During the ... Stress Affects a Gastrin-Releasing Peptide System in the Spinal Cord That Mediates Sexual Function: Implications for ...

Peptides, Peptide hormones, Mammal genes, Melanocortin receptor antagonists). ... Pritchard LE, White A (October 2005). "Agouti-related protein: more than a melanocortin-4 receptor antagonist?". Peptides. 26 ( ... Agouti signalling peptide adopts an inhibitor cystine knot motif. Along with the homologous Agouti-related peptide, these are ... Peptides. 26 (10): 1771-81. doi:10.1016/j.peptides.2004.12.024. PMID 15961186. S2CID 9749408. Millhauser GL, McNulty JC, ...

... is a potent, non-peptide, selective vasopressin receptor antagonist. It is a member of the vaptan class of drugs. V2 ... Lixivaptan (VPA-985) is an orally-active, non-peptide, selective vasopressin 2 receptor antagonist being developed as an ... Because intracellular cAMP is a secondary messenger for vasopressin acting at V2R (vasopressin receptor 2), V2 receptor ... V2 receptor antagonists may have utility as therapies for ADPKD. Genetic mutations associated with ADPKD cause an increase in ...

Design of nonpeptidal ligands for a peptide receptor: cholecystokinin antagonists. Journal of Medicinal Chemistry. 1987 Jul;30( ... It acts as a selective antagonist for the cholecystokinin receptor CCKA, and has been used as a lead compound for the ... Molecular modelling of asperlicin derived cholecystokinin A receptor antagonists. European Journal of Pharmacology. 1992 Aug 3; ...

... interaction with a peptide model of the human TLR4 ectodomain". Journal of Trace Elements in Medicine and Biology. 44: 151-160 ... TLR4 is a transmembrane protein, member of the toll-like receptor family, which belongs to the pattern recognition receptor ( ... MyD88 signaling involves the activation of IL-1 Receptor-Associated Kinases (IRAKs) and the adaptor molecules TNF Receptor- ... Pålsson-McDermott EM, O'Neill LA (October 2004). "Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 ...