Receptors,+Interleukin-15 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (CS1 maint: date and ... Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha ... PDB: 2B5I​Wang X, Rickert M, Garcia KC (November 2005). "Structure of the quaternary complex of interleukin-2 with its alpha, ... beta, and gammac receptors". Science. 310 (5751): 1159-63. Bibcode:2005Sci...310.1159W. doi:10.1126/science.1117893. PMID ...

"Identification of an interleukin-15alpha receptor-binding site on human interleukin-15". J. Biol. Chem. 279 (23): 24313-22. doi ... Jacob CO, Mykytyn K, Varcony T, Drabkin HA (1993). "Mapping of the interleukin 5 receptor gene to human chromosome 3 p25-p26 ... Two of these subunits, CD122 and CD132, are shared with the receptor for IL-2, but IL-2 receptor has an additional subunit ( ... Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene ...

... interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various ... "Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor". Science. 262 (5141): 1877-80. ... Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others. Interleukin-7 ... The interleukin-7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - ...

... a receptor subunit also shared by the receptors for interleukin 2 (IL2), interleukin 7 (IL7) and interleukin 15 (IL15). This ... Interleukin 21 receptor is a type I cytokine receptor. IL21R is its human gene. The protein encoded by this gene is a cytokine ... 2005). "Interleukin-21 receptor gene induction in human T cells is mediated by T-cell receptor-induced Sp1 activity". Mol. Cell ... 2004). "Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of ...

Its receptors were similarly renamed: Interleukin 8 receptor, alpha - CXCR1 Interleukin 8 receptor, beta - CXCR2 GRCh38: ... interleukin-1 beta, interleukin-6 and interleukin-8 in the pathogenesis of the otitis media with effusion". Eur. Cytokine Netw ... Brat DJ, Bellail AC, Van Meir EG (2005). "The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis ... Some benzodiazepines have inhibitory effects on the adenosine A2B receptor mediated secretion of interleukin-8 in human mast ...

NKG2G is a key stimulatory cell surface receptor. A low expression of the receptor is observed already in the early NK cells ... March 2011). "Interleukin 10 decreases MICA expression on melanoma cell surface". Immunology and Cell Biology. 89 (3): 447-57. ... For priming of T cells, binding of ligand on T cell receptors (TCR), co-stimulation by membrane receptors and cytokines are all ... NKG2D is an activating receptor (transmembrane protein) belonging to the NKG2 family of C-type lectin-like receptors. NKG2D is ...

As a signaling molecule, interleukin 11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; ... Sims NA, Jenkins BJ, Nakamura A, Quinn JM, Li R, Gillespie MT, Ernst M, Robb L, Martin TJ (July 2005). "Interleukin-11 receptor ... Barton VA, Hall MA, Hudson KR, Heath JK (November 2000). "Interleukin-11 signals through the formation of a hexameric receptor ... Yang YC, Yin T (December 1992). "Interleukin-11 and its receptor". BioFactors. 4 (1): 15-21. PMID 1292471. Bhatia M, Davenport ...

It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) ... Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of interleukins ... Renauld J (1995). "Interleukin-9: Structural characteristics and biologic properties". Cytokines: Interleukins and Their ... "A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth ...

IL-10 has been shown to interact with Interleukin 10 receptor, alpha subunit. The receptor complex for IL-10 also requires the ... Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001). "Interleukin-10 and the interleukin-10 receptor". Annual Review of ... Moore KW, de Waal Malefyt R, Coffman RL, O'Garra A (2001-01-01). "Interleukin-10 and the interleukin-10 receptor". Annual ... IL-10 signals through a receptor complex consisting of two IL-10 receptor-1 and two IL-10 receptor-2 proteins. Consequently, ...

Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also ... The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma ... "Entrez Gene: IL9R interleukin 9 receptor". Sliva, D; Gu M; Zhu Y X; Chen J; Tsai S; Du X; Yang Y C (February 2000). "14-3-3zeta ... Interleukin-9 receptor has been shown to interact with YWHAZ. Cluster of differentiation GRCh38: Ensembl release 89: ...

... (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory ... "Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E". Immunity. 35 (4): 611-21. ... July 2006). "Cutting edge: interleukin 17 signals through a heteromeric receptor complex". Journal of Immunology. 177 (1): 36-9 ... November 1997). "Molecular characterization of the human interleukin (IL)-17 receptor". Cytokine. 9 (11): 794-800. doi:10.1006/ ...

Interleukin 6 receptor (IL6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. Interleukin 6 ... The interleukin-6 receptor can serve as an alpha-receptor for CTNF". J. Biol. Chem. 278 (11): 9528-35. doi:10.1074/jbc. ... The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer ... Interleukin-6 receptor has been shown to interact with Interleukin 6 and ciliary neurotrophic factor. Cluster of ...

The interleukin-23 receptor is a type I cytokine receptor. It is encoded in human by the IL23R gene. In complex with the ... IL23R interleukin 23 receptor". Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, et al. (June 2002). "A receptor ... Overview of all the structural information available in the PDB for UniProt: Q5VWK5 (Interleukin-23 receptor) at the PDBe-KB. ( ... interleukin-12 receptor β1 subunit (IL-12Rβ1), it is activated by the cytokine interleukin 23 (IL-23). The IL23R mRNA is 2.8 ...

... interleukin-8 receptor A (IL-8RA) and interleukin-8 receptor B (IL-8RB). These receptors are generally found on human ... "Structure and Functional Expression of a Human Interleukin-8 Receptor". Science - via ProQuest. Receptors,+Interleukin-8 at the ... The interleukin-8 receptors (IL-8R) are two 7-transmembrane proteins in the G-protein coupled-receptor family: ... IL-8RA is highly specific for interleukin-8 and only responds when this particular ligand is bound to its receptor site, ...

May 1994). "Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor". Science. 264 ( ... Together with Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-7 (IL-7), Interleukin-9 (IL-9), granulocyte colony- ... Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with ... A hematopoietin receptor, the IL-15 receptor, that binds IL-15 propagates its function. Some subunits of the IL-15 receptor are ...

Interleukin 8 receptor, alpha Interleukin 8 Interleukin Interleukin receptor Cluster of differentiation G protein-coupled ... "Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to ... "Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to ... Interleukin 8 receptor, beta is a chemokine receptor. IL8RB is also known as CXCR2, and CXCR2 is now the IUPHAR Committee on ...

IL-1RN is an agent that binds non-productively to the cell surface interleukin-1 receptor (IL-1R), the same receptor that binds ... The interleukin-1 receptor antagonist protein (IL-1RN) is a protein that in humans is encoded by the IL1RN gene. IL-1RN was ... "Entrez Gene: IL1RN interleukin 1 receptor antagonist". Langdahl BL, Løkke E, Carstens M, Stenkjaer LL, Eriksen EF (March 2000 ... Interleukin+1+Receptor+Antagonist+Protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles ...

"The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor ... Interleukin 10 receptor, beta subunit is a subunit for the interleukin-10 receptor. IL10RB is its human gene. IL10RB has also ... 1998). "The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor". J. Exp. Med. 187 (4): 571-8. doi: ... "Entrez Gene: IL10RB interleukin 10 receptor, beta". Lutfalla G, McInnis MG, Antonarakis SE, Uzé G (1995). "Structure of the ...

... is a subunit for the interleukin-10 receptor. IL10RA, is its human gene. IL10RA has also ... Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Interleukin 10 receptor, alpha subunit ... Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (1994). "A receptor for interleukin 10 is related to interferon receptors". ... IL10RA interleukin 10 receptor, alpha". Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, Moore KW (December 1993). "A receptor for ...

Interleukin 11 receptor, alpha subunit is a subunit of the interleukin 11 receptor. IL11RA is its human gene. Interleukin 11 is ... This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor ... "Entrez Gene: IL11RA interleukin 11 receptor, alpha". Chérel M, Sorel M, Lebeau B, et al. (1995). "Molecular cloning of two ... 2007). "Expression of interleukin-11 (IL-11) and IL-11 receptor alpha in human gastric carcinoma and IL-11 upregulates the ...

The receptor for interleukin-4 is known as the IL-4Rα. This receptor exists in 3 different complexes throughout the body. Type ... Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor ... Interleukin-4 from Gentaur Recombinant Human Interleukin-4 from Cornell University Interleukin-4 from Allergy Glossary at ... Puri S, Joshi BH, Sarkar C, Mahapatra AK, Hussain E, Sinha S (May 2005). "Expression and structure of interleukin 4 receptors ...

... which is called type I IL-1 receptor (IL-1RI). There is a third ligand of this receptor - the Interleukin 1 receptor antagonist ... "Interleukins and interleukin receptors - HUGO Gene Nomenclature Committee". www.genenames.org. Archived from the original on 15 ... April 2002). "Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but ... The amount of IL-18 receptor mRNA in the endometrium as well as the ratio of the amount of binding protein to interleukin is ...

The IL-17 receptor family consists of five, broadly distributed receptors (IL-17RA, B, C, D and E) that present with individual ... Moseley TA, Haudenschild DR, Rose L, Reddi AH (April 2003). "Interleukin-17 family and IL-17 receptors". Cytokine & Growth ... Signal transduction by these receptors is as diverse as their distribution. These receptors do not exhibit a significant ... Mudigonda P, Mudigonda T, Feneran AN, Alamdari HS, Sandoval L, Feldman SR (October 2012). "Interleukin-23 and interleukin-17: ...

Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 ... Interleukin 5 receptor alpha subunit has been shown to interact with: Interleukin 5, Janus kinase 2, Protein unc-119 homolog, ... The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is ... "Multisite mutagenesis of interleukin 5 differentiates sites for receptor recognition and receptor activation". Biochemistry. 39 ...

Friedmann MC, Migone TS, Russell SM, Leonard WJ (March 1996). "Different interleukin 2 receptor beta-chain tyrosines couple to ... Patients are typically treated for five consecutive days, three times a day, for fifteen minutes. The following approximately ... Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5-16 kDa protein ... Malek TR, Castro I (August 2010). "Interleukin-2 receptor signaling: at the interface between tolerance and immunity". Immunity ...

IL-29 receptor signals through JAK-STAT pathways leading to activated expression of interferon-stimulated genes and production ... Interleukin-29 (IL-29) is a cytokine and it belongs to type III interferons group, also termed interferons λ (IFN-λ). IL-29 ( ... "Entrez Gene: interleukin 29 (interferon". Wang JM, Huang AF, Xu WD, Su LC (December 2019). "Insights into IL-29: Emerging role ... It binds to a heterodimeric receptor composed of one subunit IFNL1R specific for IFN-λ and a second subunit IL10RB shared among ...

Zhu MH, Berry JA, Russell SM, Leonard WJ (April 1998). "Delineation of the regions of interleukin-2 (IL-2) receptor beta chain ... cardiotrophin-1 receptor (CT-1R), ciliary neurotrophic factor receptor (CNTF-R), neurotrophin-1 receptor (NNT-1R) and Leptin-R ... Ueda T, Bruchovsky N, Sadar MD (March 2002). "Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK ... Friedmann MC, Migone TS, Russell SM, Leonard WJ (1996). "Different interleukin 2 receptor beta-chain tyrosines couple to at ...

"JAK3 associates with the human interleukin 4 receptor and is tyrosine phosphorylated following receptor triggering". Oncogene. ... JAK3 is involved in signal transduction by receptors that employ the common gamma chain (γc) of the type I cytokine receptor ... Cytokine binding induces the association of separate cytokine receptor subunits and the activation of the receptor-associated ... They are cytosolic tyrosine kinases that are specifically associated with cytokine receptors. Since cytokine receptor proteins ...

Johnston JA, Wang LM, Hanson EP, Sun XJ, White MF, Oakes SA, Pierce JH, O'Shea JJ (December 1995). "Interleukins 2, 4, 7, and ... Insulin receptor substrate 1 plays a key role in transmitting signals from the insulin receptor (IR) and insulin-like growth ... IRS-1 integrates signalling from insulin receptor (InsR), insulin-like growth factor-1 receptor (IGF1R) and many other cytokine ... Tyrosine phosphorylation of the insulin receptors or IGF-1 receptors, upon extracellular ligand binding, induces the ...

November 1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". ... "Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 ... Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B- ... May 1998). "Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency". Science. 280 (5368): 1432-5. ...