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*  Ligand binding assay
"Detecting ligand interactions with G protein-coupled receptors in real-time on living cells". Biochemical and Biophysical ... is a method that is used to purify or enrich a specific protein, or a group of proteins, using an antibody from a complex ... high specific activity to detect low receptor densities, and receptor specificity. Levels of radioactivity for a radioligand ( ... The immobilized protein complex can be accomplished either in a single step or successively. IP can also be used in conjunction ...
*  GPER
G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans ... This protein is a member of the rhodopsin-like family of G protein-coupled receptors and is a multi-pass membrane protein that ... "Estrogen (G protein coupled) Receptor". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and ... Chimento A, Sirianni R, Casaburi I, Pezzi V (2014). "Role of estrogen receptors and g protein-coupled estrogen receptor in ...
*  G protein-coupled receptor
G-protein-coupled receptor kinases (GRKs) are key modulators of G-protein-coupled receptor (GPCR) signaling. They constitute a ... 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors (GPLR), constitute a large protein ... G protein-coupled receptors database List of MeSH codes (D12.776) Metabotropic receptor Orphan receptor Pepducins, a class of ... doi:10.1093/protein/7.2.195. PMID 8170923. Kolakowski LF (1994). "GCRDb: a G-protein-coupled receptor database". Receptors & ...
*  Adhesion G protein-coupled receptor
Adhesion G protein-coupled receptors (adhesion GPCRs) are a class of 33 human protein receptors with a broad distribution in ... "The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity". J Biol Chem. 286: 28914- ... "Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif". The ... Formal G protein-coupled signalling has been demonstrated for a number for adhesion GPCRs, however, the orphan receptor status ...
*  G protein-coupled receptors database
G protein-coupled receptors Isberg, Vignir; Vroling, Bas; Kant, Rob van der; Li, Kang; Vriend, Gert; Gloriam, David (2014-01-01 ... GPCRdb contains data, web tools and diagrams for G protein-coupled receptors (GPCRs). It stores a manual annotation of all GPCR ... "GPCRDB: an information system for G protein-coupled receptors". Nucleic Acids Research. 42 (D1): D422-D425. doi:10.1093/nar/ ... The GPCRdb browsing system is structured on the following data content: GPCRdb Receptors Signal Proteins Ligands Drugs Crystal ...
*  Proton-sensing G protein-coupled receptors
... are transmembrane receptors which sense acidic pH and include GPR132 (G2A), GPR4, ... The four known proton-sensing G protein-coupled receptors are Class A receptors in subfamily A15. Pain sensation can be ... Proton-sensing G protein-coupled receptors have been shown to be expressed in small-diameter neurons responsible for ... "Abnormalities in Osteoclastogenesis and Decreased Tumorigenesis in Mice Deficient for Ovarian Cancer G Protein-Coupled Receptor ...
*  G protein-coupled receptor kinase
Ma L, Gao J, Chen X (2005). "G Protein-Coupled Receptor Kinases". In Devi LA. The G Protein-Coupled Receptors Handbook ( ... "G Protein-Coupled Kinases and Desensitization of Receptors". In Bernstein G, Tatsuya H. G protein-coupled receptors. Boca Raton ... G protein-coupled receptor kinases (GRKs, GPCRKs) are a family of protein kinases that regulate the activity of G protein- ... Defects in GRK1 result in Oguchi disease 2. Downregulation and upregulation G protein-coupled receptor Phosphorylation Protein ...
*  Retinal G protein coupled receptor
RPE-retinal G protein-coupled receptor also known as RGR-opsin is a protein that in humans is encoded by the RGR gene. RGR- ... "Entrez Gene: RGR retinal G protein coupled receptor". Jiang M, Pandey S, Fong HK (Dec 1993). "An opsin homologue in the retina ... Yang M, Fong HK (Feb 2002). "Synthesis of the all-trans-retinal chromophore of retinal G protein-coupled receptor opsin in ... Hao, W; Fong, HK (5 March 1999). "The endogenous chromophore of retinal G protein-coupled receptor opsin from the pigment ...
*  G protein-coupled receptor kinase 7
This gene encodes a member of the G protein-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is ... G protein-coupled receptor kinase 7 also known as GRK7 is an enzyme which in humans is encoded by the GRK7 gene. ... "Species-specific differences in expression of G-protein-coupled receptor kinase (GRK) 7 and GRK1 in mammalian cone ... specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their ...
*  Retinoic acid-inducible orphan G protein-coupled receptor
The Retinoic Acid-Inducible orphan G-protein-coupled receptors (RAIG) are a group of four closely related G protein-coupled ... In addition, RAIG receptors interact with members of the frizzled class of G protein-coupled receptors and appear to activate ... "Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short ... "Retinoic Acid-Inducible G Protein-Coupled Receptors Bind to Frizzled Receptors and May Activate Non-canonical Wnt Signaling". ...
*  G protein-coupled bile acid receptor
The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor ... This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This protein functions as a cell surface ... 2007). "Cross-talk between G protein-coupled receptor and epidermal growth factor receptor signaling pathways contributes to ... 2003). "A G protein-coupled receptor responsive to bile acids". J. Biol. Chem. 278 (11): 9435-40. doi:10.1074/jbc.M209706200. ...
*  Melatonin
"Melatonin receptors , G protein-coupled receptors , IUPHAR/BPS Guide to Pharmacology". www.guidetopharmacology.org. Retrieved ... These are both G-protein coupled membrane receptors. When used several hours before sleep according to the phase response curve ... Many of its biological effects in animals are produced through activation of melatonin receptors, while others are due to its ... Any positive immunological effect is thought to be the result of melatonin acting on high-affinity receptors (MT1 and MT2) ...
*  Arrestin beta 2
Lefkowitz RJ (July 1998). "G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor ... arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause ... "Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking". ... "A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation". The Journal of ...
*  GPCR neuropeptide receptor
"G-Protein Coupled Receptors". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical ... GPCR neuropeptide receptors are G-protein coupled receptors which bind various neuropeptides. Members include: Neuropeptide B/W ... "Receptor for the pain modulatory neuropeptides FF and AF is an orphan G protein-coupled receptor". J. Biol. Chem. 275 (34): ... a novel G protein-coupled receptor related to asthma". Am. J. Respir. Cell Mol. Biol. 33 (3): 262-70. doi:10.1165/rcmb.2004- ...
*  Arrestin beta 1
1998). "Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor ... Lefkowitz RJ (1998). "G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling ... arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause ... Bennett TA, Maestas DC, Prossnitz ER (2000). "Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated ...
*  GPR112
G protein-coupled receptor 112 is a protein encoded by the ADGRG4 gene. GPR112 is a member of the adhesion GPCR family. ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... GPR112 G protein-coupled receptor 112". Hamann, J; Aust, G; Araç, D; Engel, FB; Formstone, C; Fredriksson, R; Hall, RA; Harty, ...
*  GPR97
G-protein coupled receptor 97 also known as adhesion G protein-coupled receptor G3 (ADGRG3) is a protein that in humans is ... Gupte J, Swaminath G, Danao J, Tian H, Li Y, Wu X (Apr 2012). "Signaling property study of adhesion G-protein-coupled receptors ... "Entrez Gene: GPR97 G protein-coupled receptor 97". Hamann J, Aust G, Araç D, Engel FB, Formstone C, Fredriksson R, Hall RA, ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ...
*  EMR3
Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... adhesion class G protein-coupled receptors take the stage". Science signaling. 6 (276): re3. doi:10.1126/scisignal.2003825. ... EGF-like module-containing mucin-like hormone receptor-like 3 is a protein encoded by the ADGRE3 gene. EMR3 is a member of the ... The protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. A potential ligand of ...
*  EMR1
Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... adhesion class G protein-coupled receptors take the stage". Science signaling. 6 (276): re3. doi:10.1126/scisignal.2003825. ... EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a protein encoded by the ADGRE1 gene. EMR1 ... "The eosinophil surface receptor epidermal growth factor-like module containing mucin-like hormone receptor 1 (EMR1): a novel ...
*  GPR128
G protein-coupled receptor 128 is a protein encoded by the ADGRG7 gene. GPR128 is a member of the adhesion GPCR family. ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Letters. ...
*  GPR114
G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. ... GPR114 G protein-coupled receptor 114". Fredriksson R, Lagerström MC, Höglund PJ, Schiöth HB (Nov 2002). "Novel human G protein ... Gupte J, Swaminath G, Danao J, Tian H, Li Y, Wu X (Apr 2012). "Signaling property study of adhesion G-protein-coupled receptors ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ...
*  GPR126
G protein-coupled receptor 126 also known as VIGR and DREG is a protein encoded by the ADGRG6 gene. GPR126 is a member of the ... Monk KR, Naylor SG, Glenn TD, Mercurio S, Perlin JR, Dominguez C, Moens CB, Talbot WS (Sep 2009). "A G protein-coupled receptor ... "Entrez Gene: GPR126 G protein-coupled receptor 126". Hamann J, Aust G, Araç D, Engel FB, Formstone C, Fredriksson R, Hall RA, ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ...
*  GPR56
G protein-coupled receptor 56 also known as TM7XN1 is a protein encoded by the ADGRG1 gene. GPR56 is a member of the adhesion ... Luo R, Jeong SJ, Jin Z, Strokes N, Li S, Piao X (Aug 2011). "G protein-coupled receptor 56 and collagen III, a receptor-ligand ... "The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity". The Journal of ... Iguchi T, Sakata K, Yoshizaki K, Tago K, Mizuno N, Itoh H (May 2008). "Orphan G protein-coupled receptor GPR56 regulates neural ...
*  GPR64
G protein-coupled receptor 64 also known as HE6 is a protein encoded by the ADGRG2 gene. GPR64 is a member of the adhesion GPCR ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... "G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1". The Journal of ...
*  EMR2
"Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif". The ... Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... ISBN 1-4419-7912-3. Langenhan T, Aust G, Hamann J (May 2013). "Sticky signaling--adhesion class G protein-coupled receptors ... cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor ...
*  Guineesine
"Small Molecules from Nature Targeting G-Protein Coupled Cannabinoid Receptors: Potential Leads for Drug Discovery and ... In addition, the analgesic and catatonic effects were reversed by the cannabinoid receptor type 1 (CB1) inverse agonist ...
*  CD97
Adhesion G protein-coupled receptors". Pharmacological Reviews. 67 (2): 338-67. doi:10.1124/pr.114.009647. PMC 4394687 . PMID ... adhesion class G protein-coupled receptors take the stage". Science signaling. 6 (276): re3. doi:10.1126/scisignal.2003825. ... "Structural and functional characterization of a novel T cell receptor co-regulatory protein complex, CD97-CD55". The Journal of ... Cluster of differentiation 97 is a protein also known as BL-Ac[F2] encoded by the ADGRE5 gene. CD97 is a member of the adhesion ...