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*  CXC chemokine receptors
The chemokine receptor CXCR5 is expressed on B cells and CD4+ Tfh cells and is involved in lymphocyte homing and the ... "Chemokine Receptors". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. ... They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven ... However, CXCR6 is more closely related in structure to CC chemokine receptors than to other CXC chemokine receptors. CXCR7 was ...
*  CXCL13
... and elicits its effects by interacting with chemokine receptor CXCR5. CXCL13 and its receptor CXCR5 control the organization of ... selectively attracts B lymphocytes via BLR1/CXCR5". J. Exp. Med. 187 (4): 655-60. doi:10.1084/jem.187.4.655. PMC 2212150 . PMID ... "A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1". Nature. 391 (6669): 799-803. doi ...
*  Lymph node stromal cell
For example, Naive T cells express the CCR7 receptor for the chemokine CCL21. and B cells exhibit CXCR5 receptors for chemokine ... They also express the Fc receptors, CD16, CD23 and CD32; the complement receptors CD21 and CD35 and complement components. The ... and dendritic cells express a surface CCR7 receptor. This type of receptor interacts with the chemokine CCL21, produced by ... FRCs express chemokines such as CCL21 and CCL19 which assist the movement of T cells and dentritic cells with CCR7 receptors. ...
*  CXCR5
C-X-C chemokine receptor type 5 (CXC-R5) also known as CD185 (cluster of differentiation 185) or Burkitt lymphoma receptor 1 ( ... In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The BLR1 / CXCR5 gene is specifically expressed in Burkitt's ... Chan CC, Shen D, Hackett JJ, Buggage RR, Tuaillon N (February 2003). "Expression of chemokine receptors, CXCR4 and CXCR5, and ... Müller G, Lipp M (September 2001). "Signal transduction by the chemokine receptor CXCR5: structural requirements for G protein ...
*  Follicular B helper T cells
... and are identified by their constitutive expression of the B cell follicle homing receptor CXCR5. Upon cellular interaction and ... which binds and stimulates the B cell surface receptor CD40. TFH cell-dependent paracrine activation of B cell CD40 results in ... "Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor ( ...
*  TP53
Suppression of p53 in human breast cancer cells is shown to lead to increased CXCR5 chemokine receptor gene expression and ... "p53-dependent expression of CXCR5 chemokine receptor in MCF-7 breast cancer cells". Scientific Reports. 5 (5): 9330. doi: ... "Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ...
*  Follicular dendritic cells
B cells lacking CXCR5, the receptor for CXCL13, still enter the white pulp, but are mislocalized and disorganized. To generate ... TNF-a binds on the TNFRI receptor, while LT interacts with LTβ-receptor expressed on FDC precursors. In mice lacking B cells, ... Follicular DCs have high expression of complement receptors CR1 and CR2 (CD 35 and CD 21 respectively) and Fc-receptor FcγRIIb ... Follicular DCs receptors CR1, CR2 and FcγRIIb trap antigen opsonized by complement or antibodies. To become selected as a ...
*  Rhodopsin-like receptors
... receptor 3 (CXCR3) Chemokine (C-X-C motif) receptor 4 (CXCR4, Fusin) Chemokine (C-X-C motif) receptor 5 (CXCR5) Chemokine (C-X- ... chemokine receptor (DARC, DUFF) G Protein-coupled Receptor 30 (GPER, CML2, GPCR estrogen receptor) Angiotensin II receptor ... Opioid receptor InterPro: IPR001418 delta Opioid receptor (OPRD1, OPRD) kappa Opioid receptor (OPRK1, OPRK) mu Opioid receptor ... Motilin receptor (MLNR, GPR38) Anaphylatoxin receptors InterPro: IPR002234 C3a receptor (C3AR1, C3AR) C5a receptor (C5AR1, C5AR ...
*  RBP3
"Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature ...
*  Chemokine
Among other homeostatic chemokine receptors include: CCR9, CCR10, and CXCR5, which are important as part of the cell addresses ... Chemokine receptors are G protein-coupled receptors containing 7 transmembrane domains that are found on the surface of ... G proteins are coupled to the C-terminal end of the chemokine receptor to allow intracellular signaling after receptor ... associated with binding receptor and inflammatory chemokines. This often complicates research on receptor-specific therapeutics ...
*  BLR
... a hunting rifle Burkitt lymphoma receptor 1 (BLR1), also known as CXCR5 Blacklight: Retribution, a free first-person shooter ...
*  C-C chemokine receptor type 7
Müller G, Lipp M (Jun 2003). "Shaping up adaptive immunity: the impact of CCR7 and CXCR5 on lymphocyte trafficking". ... The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene ... C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. Two ligands have been identified for ... This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. CCR7 has been shown to stimulate ...
*  Idelalisib
It also inhibits several cell signaling pathways, including B-cell receptor (BCR) signaling and the CXCR4 and CXCR5 signaling, ...
*  Sjögren syndrome
B-cell activation through CXCR5-directed recruitment to lymphoid follicles and B-cell receptor (BCR) activation involving BLK, ... Takeda, K., Kaisho, T. & Akira, S. Toll-like receptors" Annu. Rev. Immunol 2003; 21, 335-376 Pflugfelder S. C.; et al. (1993 ... Associations with polymorphisms located at six independent loci were also detected; IRF5, STAT4, BLK, IL12A, TNIP1, and CXCR5. ... Perrier, S; Coussediere, C; Dubost, JJ; Albuisson, E; Sauvezie, B (1998). "IL-1 receptor antagonist (IL-1RA) gene polymorphism ...
*  CCR5
... and HIV co-receptor activity. HIV-1 most commonly uses the chemokine receptors CCR5 and/or CXCR4 as co-receptors to enter ... Lipp M, Müller G (2003). "Shaping up adaptive immunity: the impact of CCR7 and CXCR5 on lymphocyte trafficking". Verhandlungen ... It is a G protein-coupled receptor which functions as a chemokine receptor in the CC chemokine group. CCR5's cognate ligands ... Cutler CW, Jotwani R (2006). "Oral mucosal expression of HIV-1 receptors, co-receptors, and alpha-defensins: tableau of ...
*  Eugene C. Butcher
He and his research team have shown that lymphocytes use a variety of different adhesion molecules or "homing receptors" to ... "The germinal center response is impaired in the absence of T cell-expressed CXCR5." Eur J Immunol 2007; 37: 1: 100-9 ... The team is also exploring mechanisms that imprint lymphocyte homing and chemokine receptor expression during tissue-specific ... Their studies have shown that these adhesion receptors act coordinately with G protein-linked serpentine chemoattractant ...
*  Federica Sallusto
Rasheed AU, Rahn HP, Sallusto F, Lipp M, Muller G. Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T ... Role of chemokine receptors in positioning T cells for priming and Th1- or Th2-mediated responses. Immunol Today 1998, 19: 568- ... Chemoattractants and their receptors in homeostasis and inflammation. Curr Opin Immunol 2004, 16:724-731. Rivino L, Messi M, ... Sallusto F, Kremmer E, Palermo B, Hoy A, Ponath P, Qin S, Förster R, Lipp M, Lanzavecchia A. Switch in chemokine receptor ...
*  PEG10
... and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1". The ... "PEG10 activation by co-stimulation of CXCR5 and CCR7 essentially contributes to resistance to apoptosis in CD19+CD34+ B cells ... and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site ...
*  MEF2C
"Synergistic activation of the N-methyl-D-aspartate receptor subunit 1 promoter by myocyte enhancer factor 2C and Sp1". The ... and responsible for reduced CXCR5 gene promoter activity in B-cells during activation, that could lead to decreased autoimmune ... "Synergistic activation of the N-methyl-D-aspartate receptor subunit 1 promoter by myocyte enhancer factor 2C and Sp1". The ... "The A Allele of the Single-Nucleotide Polymorphism rs630923 Creates a Binding Site for MEF2C Resulting in Reduced CXCR5 ...