Loading...
*  Proopiomelanocortin
... ε-Melanocyte-Stimulating Hormone (ε-MSH, present in some teleosts ) Corticotropin (Adrenocorticotropic Hormone, or ACTH ... Each of these peptides is packaged in large dense-core vesicles that are released from the cells by exocytosis in response to ... Two humans with POMC deficiency have been treated with setmelanotide, a melanocortin-4 receptor agonist. Proopiomelanocortin ... α-Melanocyte-Stimulating Hormone, or α-MSH) β-Melanotropin (β-MSH) γ-Melanotropin (γ-MSH) 𝛿-Melanocyte-Stimulating Hormone (𝛿- ...
*  Critical illness-related corticosteroid insufficiency
This is partly due to an increased secretion of corticotropin-releasing hormone (CRH) and adrenocorticotropic hormone (ACTH). ... There is also an increase in the number and affinity of glucocorticoid receptors. Levels of corticosteroid-binding globulin ( ... May 2003). "Adrenocortical hormones in survivors and nonsurvivors of severe sepsis: diverse time course of ... Combined with decreased glucocorticoid receptor sensitivity and tissue response to corticosteroids, this adrenal insufficiency ...
*  Corticotropin-releasing hormone receptor
Corticotropin-releasing hormone receptors (CRHRs), also known as corticotropin-releasing factor receptors (CRFRs) are a G ... Corticotropin-releasing hormone receptors at the US National Library of Medicine Medical Subject Headings (MeSH). ... protein-coupled receptor family that binds corticotropin-releasing hormone (CRH). There are two receptors in the family, ... "Corticotropin-Releasing Factor Receptors". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and ...
*  Corticotropin-releasing hormone receptor 1
Corticotropin-releasing hormone Corticotropin-releasing hormone receptor Corticotropin-releasing hormone antagonist Antalarmin ... Corticotropin-releasing hormone receptor 1 has been shown to interact with Corticotropin-releasing hormone and Urocortin. ... The corticotropin-releasing hormone receptor binds corticotropin-releasing hormone, a potent mediator of endocrine, autonomic, ... Corticotropin-releasing hormone receptors at the US National Library of Medicine Medical Subject Headings (MeSH) CRF receptor ...
*  Corticotropin releasing hormone receptor 2
CRF2 receptors are type 2 G protein-coupled receptors for corticotropin-releasing hormone (CRH) that are resident in the plasma ... Corticotropin releasing hormone receptor GRCh38: Ensembl release 89: ENSG00000106113 - Ensembl, May 2017 GRCm38: Ensembl ... Corticotropin releasing hormone receptor 2 (CRHR2) is a protein, also known by the IUPHAR-recommended name CRF2, that is ... Corticotropin-releasing hormone receptors at the US National Library of Medicine Medical Subject Headings (MeSH) This article ...
*  Corticotropin-releasing hormone antagonist
... is a specific type of receptor antagonist that blocks the receptor sites for Corticotropin-releasing hormone (also known as ... Reul JM, Holsboer F (March 2002). "On the role of corticotropin-releasing hormone receptors in anxiety and depression". ... a nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing ... "Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, ...
*  Corticotropin-releasing hormone
... has been shown to interact with corticotropin-releasing hormone receptor 1. Corticotropin- ... corticotropin releasing hormone and corticotropin releasing hormone receptor genes are expressed in human skin". FEBS Lett. 374 ... Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may ... It is a releasing hormone that belongs to corticotropin-releasing factor family. In humans, it is encoded by the CRH gene. Its ...
*  Histidine decarboxylase
2005). "Corticotropin-releasing hormone receptor-1 and histidine decarboxylase expression in chronic urticaria". J. Invest. ... Finally, PLP re-forms its original Schiff base at lysine 305, and histamine is released. This mechanism is very similar to ... There are four different histamine receptors, H1, H2, H3, and H4, each of which carries a different biological significance. H1 ... Histamine Receptors". Pharmacological Reviews. 67 (3): 601-655. doi:10.1124/pr.114.010249. ISSN 1521-0081. PMC 4485016 . PMID ...
*  Sauvagine
... has been shown to interact with Corticotropin releasing hormone receptors 1 and 2. Montecucchi PC, Henschen A. Amino ... as it produces similar physiological effects to endogenous neuropeptides such as Corticotropin-releasing hormone. Sauvagine ... DOI: 10.1016/j.yfrne.2006.09.002 Lovejoy DA, de Lannoy L. Evolution and phylogeny of the corticotropin-releasing factor (CRF) ... Comparison of the biologic actions of corticotropin-releasing factor and sauvagine. Regulatory Peptides. 1982; 4(2):107-114. ...
*  Julio Licinio
"Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican- ... "Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenase". ... Licinio, J.; Wong, M.-L.; Gold, P. W. (July 1991). "Localization of interleukin-1 receptor antagonist mRNA in rat brain". ... They also showed that interleukin 1 receptor antagonist is an endogenous neuroprotective agent. They have shown that the ...
*  UCN2
"Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor ... potential role of the type-2 corticotropin-releasing hormone receptor in the control of myometrial contractility". ... Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands". Pharmacol. Rev. 55 (1 ... an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor". Proc. Natl. ...
*  Corticosteroid
Two genes of interest are CHRH1 (corticotropin-releasing hormone receptor 1) and TBX21 (transcription factor T-bet). Both genes ... and Philip Showalter Hench were awarded the Nobel Prize for Physiology and Medicine in 1950 for their work on hormones of the ... The cortico- part of the name refers to the adrenal cortex, which makes these steroid hormones. Thus a corticosteroid is a " ... Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the ...
*  UCN3
"Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor ... Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands". Pharmacological Reviews ... "Corticotropin-releasing hormone system in human adipose tissue". The Journal of Clinical Endocrinology and Metabolism. 89 (2): ... an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor". Proceedings ...
*  Anterior pituitary
Aguilera, Greti (1998-10-01). "Corticotropin Releasing Hormone, Receptor Regulation and the Stress Response". Trends in ... The hypothalamus releases gonadotropin-releasing hormone (GnRH), which stimulates the release of luteinizing hormone (LH) and ... Corticotropin releasing hormone (CRH) from the hypothalamus stimulates ACTH release in a cascading effect that ends with the ... Stress induces a release of corticotropin-releasing hormone (CRH) and vasopressin from the hypothalamus, which activates the ...
*  CP-154,526
... is a potent and selective antagonist of the corticotropin releasing hormone receptor 1 developed by Pfizer. CP- ... Antalarmin Pexacerfont Corticotropin releasing hormone antagonist Schulz DW, Mansbach RS, Sprouse J, Braselton JP, Collins J, ... Navarro-Zaragoza J, Núñez C, Laorden ML, Milanés MV (May 2010). "Effects of corticotropin-releasing factor receptor-1 ... "Corticotropin-releasing factor-1 receptor involvement in behavioral neuroadaptation to ethanol: a urocortin1-independent ...
*  BIBP-3226
"Involvement of neuropeptide Y Y1 receptors in the regulation of neuroendocrine corticotropin-releasing hormone neuronal ... as well as blocking the Y1-mediated corticotropin releasing hormone release. It has also been used as a lead compound to ... It was the first non-peptide antagonist developed for the Y1 receptor and has been widely used to help determine its functions ... Kask A, Rägo L, Harro J (August 1998). "Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: ...
*  Dennis S. Charney
... a corticotropin-releasing hormone receptor antagonist. Horn TL, Harder JB, Johnson WD, Curry PT, Parchment RE, Morrissey RL, ...
*  Stefan R. Bornstein
1998). Chronic Effects of a Nonpeptide Corticotropin-Releasing Hormone Type I Receptor Antagonist on Pituitary-Adrenal Function ... King's College London Agonist of growth hormone-releasing hormone as a potential effector for survival and proliferation of ... 2011). Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenase. ... He was the first to investigate the interactions of the two central stress hormones adrenaline and cortisol in healthy as well ...
*  Dante Cicchetti
Interactive effects of corticotropin releasing hormone receptor 1, serotonin transporter linked polymorphic region, and child ... corticotropin releasing hormone, dopamine, and oxytocin genes. Development and Psychopathology, 24(2). Cicchetti, D., Rogosch, ...
*  Antalarmin
... a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: Suppression of pituitary ACTH release and peripheral ... Corticotropin-releasing factor (CRF), also known as Corticotropin-releasing hormone, is an endogenous peptide hormone released ... "Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, ... triggers the release of corticotropin (ACTH), another hormone involved in the physiological response to stress. Chronic release ...
*  Astressin-B
... a nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing ... Miwa Y, Nagase K, Oyama N, Akino H, Yokoyama O (March 2011). "Effect of corticotropin-releasing factor receptor antagonist on ... Astressin-B (AST) is a nonselective corticotropin releasing hormone antagonist that reduces the synthesis of ACTH and cortisol ... "CRF Receptor Antagonist Astressin-B Reverses and Prevents Alopecia in CRF Over-Expressing Mice". PLoS ONE. 6: e16377. doi: ...
*  5-HT2C receptor
Stimulation of 5-HT2C receptors leads to increase of corticotropin releasing hormone (CRH) and vasopressin mRNA in the ... 5-HT receptor 5-HT2 receptor Anxiety/Aggression-Driven Depression Norepinephrine-dopamine disinhibitor GRCh38: Ensembl release ... Combination of the hormones decrease the receptor concentration in the ventral hippocampus in rats and could thus affect mood. ... Activation of this receptor by serotonin inhibits dopamine and norepinephrine release in certain areas of the brain. 5-HT2C ...
*  Beta adrenergic receptor kinase-2
2005). "Regulation of corticotropin-releasing hormone receptor type 1alpha signaling: structural determinants for G protein- ... "Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein ... Beta-adrenergic receptor kinase 2 (beta-ARK-2) also known as G-protein-coupled receptor kinase 3 (GRK3) is an enzyme that in ... 1998). "β2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor ...
*  Index of biochemistry articles
... corticotropin - corticotropin receptor - corticotropin-releasing hormone - corticotropin-releasing hormone receptor - ... thyroid hormone receptor - thyrotropin - thyrotropin receptor - thyrotropin-releasing hormone receptor - thyroxine - Timeline ... pituitary hormone receptor - pituitary hormone-regulating hormone receptor - plant protein - plasma membrane - plasmid - ... somatostatin receptor - somatotropin - somatotropin receptor - somatotropin-releasing hormone - somatropin - sp1 transcription ...
*  Verucerfont
... and activates the two corticotropin-releasing hormone receptors CRH-1 and CRH-2. This then triggers the release of ... Corticotropin releasing factor (CRF), also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is ... Antalarmin Corticotropin releasing hormone antagonists List of investigational anxiolytics Pexacerfont Zorrilla, Eric P.; ... Verucerfont blocks the CRH-1 receptor, and so reduces ACTH release following chronic stress. It is under investigation as a ...
*  Cushing's syndrome
... of the hypothalamus releases corticotropin-releasing hormone (CRH), which stimulates the pituitary gland to release ... This atrophy is associated with areas of high glucocorticoid receptor concentrations such as the hippocampus and correlates ... Voyadzis JM, Guttman-Bauman I, Santi M, Cogen P (2004). "Hypothalamic hamartoma secreting corticotropin-releasing hormone. Case ... Corticotropin releasing hormone) (tertiary hypercortisolism/hypercorticism). This causes the blood ACTH levels to be elevated ...
*  17q21.31 microdeletion syndrome
These include: The uncharacterised protein C17orf69 (also known as FLJ25168). Corticotropin releasing hormone receptor 1 (CRHR1 ...