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*  Protein primary structure
Amino acids are polymerised via peptide bonds to form a long backbone, with the different amino acid side chains protruding ... Similar to phosphorylated tyrosines, sulfated tyrosines are used for specific recognition, e.g., in chemokine receptors on the ... Protein sequencing Nucleic acid primary structure Translation Pseudo amino acid composition SANGER F (1952). "The arrangement ... listing the amino acids starting at the amino-terminal end through to the carboxyl-terminal end. Either a three letter code or ...
*  SLC1A1
Excitatory amino-acid transporter 3 is a member of the high-affinity glutamate transporters which plays an essential role in ... "Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat ... SLC1A1, also known as excitatory amino-acid transporter 3 (EAAT3), is a protein that in humans is encoded by the SLC1A1 gene. ... Excitatory amino acid transporter Glutamate transporter Solute carrier family GRCh38: Ensembl release 89: ENSG00000106688 - ...
*  Excitatory amino acid receptor ligand
... also known as glutamate receptors. They include excitatory amino acid receptor agonists and excitatory amino acid receptor ... Excitatory amino acid receptor ligands are ligands of excitatory amino acid receptors (EAARs), ...
*  Excitatory amino acid receptor antagonist
Phencyclidine Excitatory amino acid receptor agonist Excitatory amino acid reuptake inhibitor N-methyl-D-aspartate receptor ... An excitatory amino acid receptor antagonist, or glutamate receptor antagonist, is a chemical substance which antagonizes one ... Excitatory amino acid antagonists at the US National Library of Medicine Medical Subject Headings (MeSH). ... AP5 Barbiturates Dextromethorphan Dextrorphan Dizocilpine Ethanol Ibogaine Ifenprodil Ketamine Kynurenic acid Memantine Nitrous ...
*  Excitatory amino acid receptor agonist
... acid Kainic acid N-Methyl-D-aspartic acid Quisqualic acid Excitatory amino acid receptor antagonist Excitatory amino acid ... An excitatory amino acid receptor agonist, or glutamate receptor agonist, is a chemical substance which agonizes one or more of ... Excitatory amino acid agonists at the US National Library of Medicine Medical Subject Headings (MeSH) MeSH list of agents ... the glutamate receptors. Examples include: AMPA Glutamic acid Ibotenic ...
*  TAS1R1
... but are rather used to enhance receptor responses to many L-amino acids. TAS1R1 and TAS1R2 receptors have been shown to bind to ... The TAS1R1+3 receptor has been shown to respond to L-amino acids but not to their D-enantiomers or other compounds. This ... Nelson G, Chandrashekar J, Hoon MA, Feng L, Zhao G, Ryba NJ, Zuker CS (2002). "An amino-acid taste receptor". Nature. 416 (6877 ... Nelson G, Chandrashekar J, Hoon MA, Feng L, Zhao G, Ryba NJ, Zuker CS (2002). "An amino-acid taste receptor". Nature. 416 (6877 ...
*  Taste
Glutamate binds to a variant of G protein coupled glutamate receptors. It is thought that the amino acid L-glutamate bonds to a ... Savoriness The amino acid glutamic acid is responsible for savoriness, but some nucleotides (inosinic acid and guanylic acid) ... See TAS1R1 and TAS1R3 pages for a further explanation of the amino-acid taste receptor). Measuring the degree to which a ... March 2002). "An amino-acid taste receptor". Nature. 416 (6877): 199-202. doi:10.1038/nature726. PMID 11894099. Yamaguchi, ...
*  TAS1R3
... but are rather used to enhance receptor responses many to L-amino acids. The TAS1R2+3 receptor has been shown to respond to ... Nelson G, Chandrashekar J, Hoon MA, Feng L, Zhao G, Ryba NJ, Zuker CS (2002). "An amino-acid taste receptor". Nature. 416 (6877 ... Nelson G, Chandrashekar J, Hoon MA, Feng L, Zhao G, Ryba NJ, Zuker CS (2002). "An amino-acid taste receptor". Nature. 416 (6877 ... G protein-coupled receptor with seven trans-membrane domains and is a component of the heterodimeric amino acid taste receptor ...
*  Umami
2002). "An amino-acid taste receptor". Nature. 416 (6877): 199-202. Bibcode:2002Natur.416..199N. doi:10.1038/nature726. PMID ... Glutamate in acid form (glutamic acid) imparts little umami taste, whereas the salts of glutamic acid, known as glutamates, ... ISBN 978-0-547-08590-6. Smriga M, Mizukoshi T, Iwata D, Sachise E, Miyano H, Kimura T, Curtis R (August 2010). "Amino acids and ... Agostini C, Carratu B, Riva E, Sanzini E (August 2000). "Free amino acid content in standard infant formulas: comparison with ...
*  Taste receptor
The TAS1R1+TAS1R3 heterodimer receptor functions as the savory receptor, responding to L-amino acid binding, especially L- ... Nelson G, Chandrashekar J, Hoon MA, Feng L, Zhao G, Ryba NJ, Zuker CS (Mar 2002). "An amino-acid taste receptor". Nature. 416 ( ... "The G-protein coupling properties of the human sweet and amino acid taste receptors". Developmental Neurobiology. 67 (7): 948- ... or umami taste receptor is a G protein-coupled receptor with seven transmembrane domains. Ligand binding at the taste receptors ...
*  Excitatory amino acid reuptake inhibitor
GABA reuptake inhibitor Glycine reuptake inhibitor Excitatory amino acid receptor agonist Excitatory amino acid receptor ... An excitatory amino acid reuptake inhibitor (EAARI) is a type of drug which inhibits the reuptake of the excitatory ... October 2005). "Characterization of novel aryl-ether, biaryl, and fluorene aspartic acid and diaminopropionic acid analogs as ... neurotransmitters glutamate and aspartate by blocking one or more of the excitatory amino acid transporters (EAATs). Examples ...
*  HA-966
Näsström J, Karlsson U, Post C (Feb 1992). "Antinociceptive actions of different classes of excitatory amino acid receptor ... 3-Amino-1-hydroxy-pyrrolidin-2-one is a molecule used in scientific research as a glycine receptor and NMDA receptor antagonist ... Bonta IL, De Vos CJ, Grijsen H, Hillen FC, Noach EL, Sim AW (Nov 1971). "1-Hydroxy-3-amino-pyrrolidone-2(HA-966): a new GABA- ... S-(−)-HA-966 has been described as a "γ-hydroxybutyric acid (GHB)-like agent" and a "potent y-butyrolactone-like sedative", but ...
*  Glutamate receptor-interacting protein
The AMPA receptor amino acid sequence that the GRIP protein binds to is ESVKI. The conserved serine amino acid in the C- ... Research on NMDA receptor localization paved the way for research on non-NMDA receptors such as AMPA receptors. Similar to NMDA ... Glutamate receptor-interacting protein (GRIP) refers to either a family of proteins that bind to the glutamate receptor or ... ABP-L, like GRIP-1b, associates with intracellular stores of AMPA receptors. pABP-L, however, associates with AMPA receptors as ...
*  TAS1R2
G protein-coupled receptor with seven trans-membrane domains and is a component of the heterodimeric amino acid taste receptor ... "The G-protein coupling properties of the human sweet and amino acid taste receptors". Developmental Neurobiology. 67 (7): 948- ... These results are inconclusive about the existence of another sweet taste receptor, but show that the TAS1R2+3 receptors are ... and guanidinoacetic acid. Research initially suggested that rat receptors did not respond to many other natural and artificial ...
*  Bicuculline
... excitatory amino acid) receptor function. The action of bicuculline is primarily on the ionotropic GABAA receptors, which are ... These receptors are the major targets for benzodiazepines and related anxiolytic drugs. The half-maximal inhibitory ... Sensitivity to bicuculline is defined by IUPHAR as a major criterion in the definition of GABAA receptors Picrotoxin Manske, R ... In addition to being a potent GABAA receptor antagonist, bicuculline can be used to block Ca2+-activated potassium channels. ...
*  Trk receptor
Normal Trk receptors do not contain amino acid or DNA sequences related to tropomyosin. The three most common types of trk ... Each type of Trk receptor tends to bind specific neurotrophins: TrkA is the receptor for NGF, TrkB the receptor for BDNF and NT ... Trk receptors All neurotrophins bind to a class of highly homologous receptor tyrosine kinases known as Trk receptors, of which ... the P75 neurotrophin receptor (P75NTR) can also reduce ligand-induced receptor ubiquitination, and delay receptor ...
*  GRID2
"The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family". FEBS Letters. 315 (3): 318-22. doi: ... Matsuda K, Yuzaki M (Mar 2012). "Cbln1 and the δ2 glutamate receptor--an orphan ligand and an orphan receptor find their ... This protein together with GluD1 belongs to the delta receptor subtype of ionotropic glutamate receptors. They possess 14-24% ... GRID2 glutamate receptor, ionotropic, delta 2". Hu W, Zuo J, De Jager PL, Heintz N (Jan 1998). "The human glutamate receptor ...
*  Cannabinoid receptor type 2
... the amino acid similarity between the two receptor subtypes is approximately 68%. The amino acid sequence of the CB2 receptor ... Approximately 360 amino acids comprise the human CB2 receptor, making it somewhat shorter than the 473-amino-acid-long CB1 ... The receptor was identified among cDNAs based on its similarity in amino-acid sequence to the cannabinoid receptor type 1 (CB1 ... The human CB1 and the CB2 receptors possess approximately 44% amino acid similarity. When only the transmembrane regions of the ...
*  SLC1A5
Kudo Y, Boyd CA (August 2002). "Changes in expression and function of syncytin and its receptor, amino acid transport system B( ... "The RD114/simian type D retrovirus receptor is a neutral amino acid transporter". Proceedings of the National Academy of ... "Truncated forms of the dual function human ASCT2 neutral amino acid transporter/retroviral receptor are translationally ... Neutral amino acid transporter B(0) is a protein that in humans is encoded by the SLC1A5 gene. Glutamate transporter Solute ...
*  Glycine receptor
The glycine receptor (abbreviated as GlyR or GLR) is the receptor of the amino acid neurotransmitter glycine. GlyR is an ... The receptor can be activated by a range of simple amino acids including glycine, β-alanine and taurine, and can be selectively ... Kuhse, J; Laube B; Magalei D; Betz H (1993). "Assembly of the inhibitory glycine receptor: identification of amino acid ... Receptors of this family are arranged as five subunits surrounding a central pore, with each subunit composed of four α helical ...
*  Benita Katzenellenbogen
"Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein". ... Characterization of the Estrogenic Potencies and Receptor Interactions of a Series of Fungal β-Resorcylic Acid Lactones". ... "Impact of Estrogen Receptor β on Gene Networks Regulated by Estrogen Receptor α in Breast Cancer Cells". Endocrinology. 147 (10 ... "Mechanistic Aspects of Estrogen Receptor Activation Probed with Constitutively Active Estrogen Receptors: Correlations with DNA ...
*  Selfotel
CGS 19755, a selective and competitive N-methyl-D-aspartate-type excitatory amino acid receptor antagonist. Journal of ... Tolerance to the cataleptic effect of the N-methyl-D-aspartate (NMDA) receptor antagonists in pigeons: cross-tolerance between ... PMID 11172782 Ikonomidou C, Turski L. Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain ... CGS 19755: a novel competitive N-methyl-D-aspartate (NMDA) receptor antagonist with anticonvulsant, anxiolytic and anti- ...
*  GPRC6A
... a promiscuous L-alpha-amino acid receptor with preference for basic amino acids". Mol. Pharmacol. 67 (3): 589-97. doi:10.1124/ ... a promiscuous L-alpha-amino acid receptor with preference for basic amino acids". Mol. Pharmacol. 67 (3): 589-97. doi:10.1124/ ... This protein functions as a receptor of L-α-amino acids, cations (e.g., calcium), osteocalcin, and steroids. It is a membrane ... G protein-coupled receptor family C group 6 member A (GPRC6A) is a protein that in humans is encoded by the GPRC6A gene. ...
*  Formyl peptide receptor 2
The 7 mouse FPR receptors have ≥50% amino acid sequence identity with each other as well as with the three human FPR receptors ... The human FPR2 gene encodes the 351 amino acid receptor, FPR2, within an intronless open reading frame. It forms a cluster with ... Eicosanoid receptor Formyl peptide receptor Lipoxin Resolvin Formyl peptide receptor 1 Formyl peptide receptor 3 GRCh38: ... FPR2 and FPR3 are termed formyl peptide receptors base on the similarities of their amino acid sequences to that of FPR1 rather ...
*  Glutamate receptor
"Identification of amino acids in the glutamate receptor, GluR3, important for antibody-binding and receptor-specific activation ... Crowder JM, Croucher MJ, Bradford HF, Collins JF (June 1987). "Excitatory amino acid receptors and depolarization-induced Ca2+ ... amino acid substitutions in the glutamate receptor family". BMC Evol. Biol. 9: 224. doi:10.1186/1471-2148-9-224. PMC 2753569 . ... "Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas". Eur. J. ...
*  Phage display
PelB (an amino acid signal sequence that targets the protein to the periplasm where a signal peptidase then cleaves off PelB) ... Then the expression of single chain Fv's (scFv), and single chain T cell receptors (scTCR) were expressed both with and without ... Usually peptides that can be fused to pVIII are 6-8 amino acids long. The size restriction seems to have less to do with ... Moreover, pIII allows for the insertion of larger protein sequences (>100 amino acids) and is more tolerant to it than pVIII. ...
*  Kynurenine 3-monooxygenase
Stone, T. W.; Perkins, M. N. (1981). "Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS". Eur. J. ... the neuroprotectant kynurenic acid through kynurenine amino transferases, or anthranilic acid by kynureninase. Kynurenine 3- ... "The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: ... Arg 83 and Tyr 97 also form polar contacts with the carboxylate in the amino acid moiety on the substrate. Kynurenine-3- ...