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*  Bradykinin receptor B1
"Two B1 and B2 bradykinin receptor antagonists fail to inhibit the Ca2+ response elicited by bradykinin in human skin ... BDKRB1 bradykinin receptor B1". Seabrook GR, Bowery BJ, Hill RG. "Bradykinin receptors in mouse and rat isolated superior ... Leeb T, Mathis SA, Leeb-Lundberg LM (1997). "The sixth transmembrane domains of the human B1 and B2 bradykinin receptors are ... Kang DS, Ryberg K, Mörgelin M, Leeb-Lundberg LM (2004). "Spontaneous formation of a proteolytic B1 and B2 bradykinin receptor ...
*  Bradykinin receptor B2
... is a G-protein coupled receptor for bradykinin, encoded by the BDKRB2 gene in humans. The B2 receptor is ... "Entrez Gene: BDKRB2 bradykinin receptor B2". "Bradykinin Receptors: B2". IUPHAR Database of Receptors and Ion Channels. ... also potentiates bradykinin action on B2 receptors. Kallidin also signals through the B2 receptor. An antagonist for the ... "Two B1 and B2 bradykinin receptor antagonists fail to inhibit the Ca2+ response elicited by bradykinin in human skin ...
*  Apelin
... and bradykinin B2 receptors". J. Biol. Chem. 279 (9): 7901-8. doi:10.1074/jbc.M306377200. PMID 14645236. O'Dowd BF, Heiber M, ... a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo". J. Biol. Chem. 279 (25): ... The apelin receptor is expressed early during the embryonic development of the heart, where it regulates the migration of cell ... Apelin receptor is also expressed in the neurons of brain areas involved in regulating water and food intake. Apelin injection ...
*  THOP1
"EP24.15 interacts with the angiotensin II type I receptor and bradykinin B2 receptor". Cell Biochem. Funct. 23 (3): 195-204. ...
*  Hereditary angioedema
Icatibant inhibits the bradykinin B2 receptor, and was approved in Europe and the USA. In hereditary angioedema, specific ... Icatibant (marketed as Firazyr) is a selective bradykinin receptor antagonist, which has been approved in Europe and was ... bradykinin receptor antagonist (Icatibant, Firazyr®, Jerini/Shire) in Europe; kallikrein inhibitor(Ecallantide, Kalbitor®, Dyax ... This results in increased amounts of bradykinin which promotes swelling. The condition may be inherited from a person's parents ...
*  Apelin receptor
2004). "Agonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptors". J. Biol. Chem. ... The apelin receptor (also known as the APJ receptor) is a G protein-coupled receptor which binds apelin and Apela/ELABELA/ ... "Apelin Receptor: APJ". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. ... 2004). "Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in ...
*  GRK5
"Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function". The Journal of ... "beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase- ... "Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C". The Journal ... "Involvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptor". The Journal of ...
*  GRK4
2001). "Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function". J. Biol. ... 2003). "Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4". Kidney Int. 62 (3): 790-8 ... 2006). "The D1 dopamine receptor is constitutively phosphorylated by G protein-coupled receptor kinase 4". Mol. Pharmacol. 69 ( ... G protein-coupled receptor kinase 4 is an enzyme that in humans is encoded by the GRK4 gene. This gene encodes a member of the ...
*  GRK6
2001). "Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function". J. Biol. ... 1998). "β2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor ... 1997). "Phosphorylation and desensitization of human endothelin A and B receptors. Evidence for G protein-coupled receptor ... G protein-coupled receptor kinase 6 is an enzyme that in humans is encoded by the GRK6 gene. This gene encodes a member of the ...
*  Beta adrenergic receptor kinase-2
2001). "Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function". J. Biol. ... "Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein ... Beta-adrenergic receptor kinase 2 (beta-ARK-2) also known as G-protein-coupled receptor kinase 3 (GRK3) is an enzyme that in ... 1998). "β2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor ...
*  Calreticulin
Abd Alla J, Reeck K, Langer A, Streichert T, Quitterer U (Sep 2009). "Calreticulin enhances B2 bradykinin receptor maturation ... binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor ... The amino terminus of calreticulin interacts with the DNA-binding domain of the glucocorticoid receptor and prevents the ... Thus, calreticulin can act as an important modulator of the regulation of gene transcription by nuclear hormone receptors. ...
*  Icatibant
... acts as a bradykinin inhibitor by blocking the binding of native bradykinin to the bradykinin B2 receptor. Icatibant ... which is a selective and specific antagonist of bradykinin B2 receptors. Bradykinin is a peptide-based hormone that is formed ... These symptoms are mediated by activation of bradykinin B2 receptors. ... Bradykinin plays an important role as the mediator of pain. Surplus bradykinin is responsible for the typical symptoms of ...
*  Menarini
"Antagonism of bradykinin B2 receptor prevents inflammatory responses in human endothelial cells by quenching the NF-kB pathway ...
*  List of MeSH codes (D12.776.543)
... receptor, bradykinin b1 MeSH D12.776.543.750.720.600.220.500 -- receptor, bradykinin b2 MeSH D12.776.543.750.720.600.250 -- ... receptor, bradykinin b1 MeSH D12.776.543.750.750.555.220.500 -- receptor, bradykinin b2 MeSH D12.776.543.750.750.555.250 -- ... receptor, bradykinin b1 MeSH D12.776.543.750.100.080.500 -- receptor, bradykinin b2 MeSH D12.776.543.750.100.125.100 -- ... receptors, bombesin MeSH D12.776.543.750.720.600.220 -- receptors, bradykinin MeSH D12.776.543.750.720.600.220.249 -- ...
*  G protein-coupled receptor
In kidney cells, the bradykinin receptor B2 has been shown to interact directly with a protein tyrosine phosphatase. The ... transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors ( ... G protein-coupled receptors database List of MeSH codes (D12.776) Metabotropic receptor Orphan receptor Pepducins, a class of ... is a receptor that can bind with stimulative signal molecules, while inhibitory hormone receptor (Ri) is a receptor that can ...
*  Bradykinin receptor
There are two Bradykinin receptors: the B1 receptor and the B2 receptor. Bradykinin receptor B1 (B1) is a G-protein coupled ... also potentiates bradykinin action on B2 receptors. Icatibant is a second generation B2 receptor antagonist which has undergone ... The bradykinin receptor family is a group of G-protein coupled receptors whose principal ligand is the protein bradykinin. ... The B1 receptor is one of two G protein-coupled receptors that have been found which bind bradykinin and mediate responses to ...
*  Jerini
... is an inhibitor of the action of the hormone bradykinin on its B2 receptor. This compound was in-licensed from Aventis in 2001 ...
*  Rhodopsin-like receptors
IPR003904 Bradykinin receptor InterPro: IPR000496 Bradykinin receptor B1 (BDKRB1, BRB1) Bradykinin receptor B2 (BDKRB2, BRB2) ... chemokine receptor (DARC, DUFF) G Protein-coupled Receptor 30 (GPER, CML2, GPCR estrogen receptor) Angiotensin II receptor ... kappa Opioid receptor (OPRK1, OPRK) mu Opioid receptor (OPRM1, OPRM) Nociceptin receptor (OPRL1, OPRX) Somatostatin receptor ... Motilin receptor (MLNR, GPR38) Anaphylatoxin receptors InterPro: IPR002234 C3a receptor (C3AR1, C3AR) C5a receptor (C5AR1, C5AR ...
*  Epoxyeicosatrienoic acid
... bradykinin or acetylcholine acting through their respective Bradykinin receptor B2 and muscarinic acetylcholine receptor M1 or ... some studies implicate EET binding to an unidentified Cell surface receptor and/or Gs protein-linked G protein-coupled receptor ... "CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho- ... express hyperactive sEH and show reduced vasodilation responses to bradykinin. Other studies find that women with pregnancy- ...
*  Bradykinin
The B2 receptor is constitutively expressed and participates in bradykinin's vasodilatory role. The kinin B1 and B2 receptors ... The B1 receptor (also called bradykinin receptor B1) is expressed only as a result of tissue injury, and is presumed to play a ... Bradykinin is a 9-amino acid peptide chain. The amino acid sequence of bradykinin is: Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg ( ... Bradykinin also causes natriuresis, contributing to the drop in blood pressure. Bradykinin raises internal calcium levels in ...
*  B2
... a subgroup of the Anatomical Therapeutic Chemical Classification System Bradykinin receptor B2, a human gene Proanthocyanidin ... B2, B02, B.II, B.2 or B-2 may refer to: B-2 Spirit, an American stealth bomber of the United States Air Force AEG B.II, a ... B2, a B type proanthocyanidin Thromboxane B2, an inactive metabolite/product of thromboxane A2 Vitamin B2 B2, a postcode area ... B2 (New York City bus) serving Brooklyn B2, the IATA airline designator code for Belavia Belarusian Airlines B2, East coast ...
*  Safotibant
This means that LF22-0542 is at least 4000 times selective for the B1 receptor over the B2 receptor. Systemic administration of ... a Novel Nonpeptidic Bradykinin B1 Receptor Antagonist". The Journal of Pharmacology and Experimental Therapeutics. 318 (1): 195 ... or rat B2 receptors at concentrations up to 10 μM. ... of 0.35 and 6.5 nM at cloned human and mouse B1 receptors, ... Safotibant (INN) also known by the research code LF22-0542 is a non-peptide bradykinin B1 antagonist. It displayed binding Ki ...
*  ACE inhibitor
... may increase levels of bradykinin while blocking the generation of angiotensin II and its activity at the AT1 receptor. This ' ... http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20%28General%20Monographs-%20A%29/ACE% ... Angiotensin II receptor antagonist Discovery and development of angiotensin receptor blockers Loop diuretic, also used to treat ... The inactivation of bradykinin and the conversion of angiotensin I to angiotensin II in the lungs was thought to be caused by ...
*  List of MeSH codes (D12.644)
... tnf receptor-associated factor 1 MeSH D12.644.360.024.500.750 --- tnf receptor-associated factor 2 MeSH D12.644.360.024.500.875 ... ephrin-b2 MeSH D12.644.276.500.800 --- ephrin-b3 MeSH D12.644.276.625 --- epidermal growth factor MeSH D12.644.276.750 --- ... bradykinin MeSH D12.644.276.875.169.400 --- kallidin MeSH D12.644.276.875.654 --- kininogens MeSH D12.644.276.875.654.350 --- ... tnf receptor-associated factor 3 MeSH D12.644.360.024.500.937 --- tnf receptor-associated factor 5 MeSH D12.644.360.024.500.968 ...
*  B1
... , B.I, B.1 or B-1 may refer to: Bradykinin receptor B1, a human gene Cinnamtannin B1, a condensed tannin found in cinnamon ... a medical-based Paralympic classification for blind sport B-1/B-2 Visa, issued by the United States to a foreign citizen ...
*  Natural product
These first messengers interact with cellular receptors which are composed of proteins. Cellular receptors in turn activate ... Vitamin B2 (riboflavin) is a constituent of FMN and FAD which are necessary for many redox reactions. Vitamin B3 (nicotinic ... Captopril is based on the peptidic bradykinin potentiating factor isolated from venom of the Brazilian arrowhead viper ( ... Because of these specific chemical-target interactions, venom constituents have proved important tools for studying receptors, ...