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*  Tridax procumbens
... in Sprague Dawley rats". Pharmacognosy Research. 5 (2): 113-7. doi:10.4103/0974-8490.110541. PMC 3685759 . PMID 23798886. Ali, ...
*  Genetically modified food controversies
Suzuki H, Mohr U, Kimmerle G (October 1979). "Spontaneous endocrine tumors in Sprague-Dawley rats". Journal of Cancer Research ... "Mortality and In-Life Patterns in Sprague-Dawley" (PDF). Huntingdon Life Sciences. Retrieved 26 October 2012. "Sprague Dawley ... Criticisms included insufficient statistical power and that Séralini's Sprague-Dawley rats were inappropriate for a lifetime ... Controversial Seralini GMO-rats paper to be retracted Pollack A (November 28, 2013). "Paper Tying Rat Cancer to Herbicide Is ...
*  Thalidomide
Study Drug Toxicity 1 49 King, C.T.G.; Kendrick, F.J. (1962). "Teratogenic effects of thalidomide in the Sprague Dawley rat". ... Similar results were also published showing these effects in rats and other species. In East Germany, the head of the central ... Effect of some therapeutic agents on the developing rat fetus. Toxicol. appl. Pharmacol. 7 409-17. Botting, Jack (April 2015 ...
*  Chlorzoxazone
Wan J, Ernstgård L, Song B, Shoaf S (2006). "Chlorzoxazone metabolism is increased in fasted Sprague-Dawley rats". J Pharm ... "Chlorzoxazone inhibit contraction of rat thoracic aorta". Eur J Pharmacol. 545 (2-3): 161-6. doi:10.1016/j.ejphar.2006.06.063. ...
*  2-Furoic acid
Hall, Iris; Wong, Oi; Reynolds, David; Chang, J. J. (2006). "Hypolipidemic Effects of 2-Furoic Acid in Sprague-Dawley Rats". ... Research on the effects of 2-furoic acid in rats showed an increase in bile salts and acute toxicity suggesting potential toxic ...
*  Laboratory rat
The Sprague Dawley rat and Long-Evans rats were developed from Wistar rats. Wistar rats are more active than others like ... Sprague Dawley®, Envigo, Inc.) is not. The average litter size of the Sprague Dawley rat is 11.0. These rats typically have a ... Rat Genome Rat Genome Database Charles River Laboratories Harlan Sprague Dawley Jax Index of Inbred Rat Strains Knock Out Rat ... This breed of rat was first produced by the Sprague-Dawley farms (later to become the Sprague-Dawley Animal Company) in Madison ...
*  Safrole
"Safrole-induced Oxidative Damage in the Liver of Sprague-Dawley Rats". Food and Chemical Toxicology. 37 (7): 697-702. doi: ... "Safrole-induced Oxidative Damage in the Liver of Sprague-Dawley Rats". Food and Chemical Toxicology. 37 (7): 697-702. doi: ... hydroxysafrole in rats. Further metabolites of safrole that have been found in urine of both rats and human include 1,2- ... In rats, safrole and related compounds produced both benign and malignant tumors after intake through the mouth. Changes in the ...
*  Xylazine
"Pharmacokinetics of ketamine and xylazine in young and old Sprague-Dawley rats". Journal of the American Association for ... In young rats, the half life is an hour. Xylazine has a large volume of distribution (Vd). The Vd is 1.9-2.5 for horse, cattle ... In scientific research, xylazine is a component of the most common anesthetic, ketamine-xylazine, which is used in rats, mice, ... in rat and human urine using GC-MS, LC-MSn, and LC-HR-MSn". Analytical and Bioanalytical Chemistry. 405 (30): 9779-89. doi: ...
*  Diet-induced obesity model
For example, in one experiment, male Sprague-Dawley rats were given either a low fat or a high fat diet, with the high fat diet ... "Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats". American Journal of Physiology. 273. " ... Rats have also been used in the diet-induced obesity model. Commonly used in medical research, rats were specifically chosen to ... The results of the study illustrate that the high fat diet rats had a higher adiposity index than the low fat diet rats. Dogs ...
*  Radiobiology evidence for protons and HZE nuclei
"In vivo mammary tumourigenesis in the Sprague-Dawley rat and microdosimetric correlates". Physics in Medicine and Biology. 49 ( ... Relative biological effectiveness factors comparing gamma rays to HZE ions were measured in mice or rats for tumors of the skin ... "The Low Carcinogenicity of Electron Radiation Relative to Argon Ions in Rat Skin". radiation research. 135: 178-188. doi: ...
*  Toluene toxicity
Laham, S; Potvin M (1987). "Biological conversion of benzaldehyde to benzylmercapturic acid in the Sprague-Dawley rat". Drug ... Studies in rats have shown that p-cresol is primarily conjugated with glucuronide to produce p-cresylglucuronide, though this ...
*  Tobacco smoking
"Acrylonitrile-induced oxidative stress and oxidative DNA damage in male Sprague-Dawley rats". Toxicol. Sci. 111 (1): 64-71. doi ... Using rat studies, withdrawal after repeated exposure to nicotine results in less responsive nucleus accumbens cells, which ... "Imaging localised dynamic changes in the nucleus accumbens following nicotine withdrawal in rats". NeuroImage. 22 (2): 847-854 ...
*  Smoking
"Acrylonitrile-induced oxidative stress and oxidative DNA damage in male Sprague-Dawley rats". Toxicol. Sci. 111 (1): 64-71. doi ...
*  Phensuximide
"Urinary tract effects of phensuximide in the Sprague-Dawley and Fischer 344 rat". J Appl Toxicol. 6 (5): 349-56. doi:10.1002/ ...
*  Heterocyclic amine
... in male Sprague-Dawley rats". Journal of Toxicology and Environmental Health. Part a. 64 (8): 645-60. doi:10.1080/ ...
*  Atomoxetine
In Sprague Dawley rats, atomoxetine reduces NR2B protein content without altering transcript levels. Aberrant glutamate and ... In rats, atomoxetine increased prefrontal cortex catecholamine concentrations without altering dopamine levels in the striatum ... However, both mouse and rat microdialysis studies have failed to find an increase in extracellular serotonin in the prefrontal ... Atomoxetine's ability to increase prefrontal cortex firing rate in anesthetized rats could not be blocked by D1 or α2- ...
*  Solanum ptychanthum
"Subchronic toxicity study of eastern black nightshade (Solanum ptychanthum) berries in Sprague-Dawley rats." Journal of Food ... A. Davis, K. Renner, C. Sprague, L. Dyer, D. Mutch (2005). Integrated Weed Management. MSU. Solanum ptychanthum at the ...
*  The Thumbs
Sprague Dawley Rats - 7" EP Sneezeguard Records Sweet Merciful Crap - 7" EP Soda Jerk Records All Lesser Devils - 7"/CD EP ... Sprague Dawley Rats "If It's Not Punk, It's Junk" CD (GFY Records, 1997.) Song- Shuck "Exploitational Sampler" CD (Creep ... Sprague Dawley Rats recording (1996), Sweet Merciful Crap (1997), Make America Strong (1998) Lee Ashlin - Drums scattered ...
*  Chlordane
"Trans-Nonachlor and cis-Nonachlor Toxicity in Sprague-Dawley Rats: Comparison with Technical Chlordane". Toxicological Sciences ...
*  2C-H
It features competitive antagonist activity at 5-HT serotonin receptor in Sprague-Dawley rat stomachs. It exhibits binding ... It has binding affinity towards 5-HT2C and 5-HT2A receptors in rats. ... affinity against rat 5-hydroxytryptamine 2C receptors using [3H]mesulergine as a radioligand. As of October 31, 2016; 2C-H is a ...
*  Glossostemon bruguieri
Water extract of G. bruguieri roots has reversed induced juvenile osteopenia in Sprague Dawley rats. However, human clinical ... Induced Juvenile Osteopenia in Rats; the Potential Therapeutic Effect of Egyptian Moghat Roots Water Extract (Glossostemon ...
*  Proteinuria
Also leptin administration to normotensive Sprague Dawley rats during pregnancy significantly increases urinary protein ... Leptin increases blood pressure and markers of endothelial activation during pregnancy in rats". BioMed Research International ...
*  Persicaria minor
... mechanisms underlying gastroprotective activities of the fractions obtained from Polygonum minus in Sprague Dawley rats". ...
*  Icariin
"Effects of icariin on hypothalamic-pituitary-adrenal axis action and cytokine levels in stressed Sprague-Dawley rats". Biol. ... It also has neuroprotective effects in rats. Liu JJ, Li SP, Wang YT (2006). "Optimization for quantitative determination of ... as well as mimicking the effects of testosterone in rats. In vitro evidence suggests it is a weak antioxidant. It has ... "Effect of lipid-based suspension of Epimedium koreanum Nakai extract on sexual behavior in rats". J Ethnopharmacol. 114 (3): ...
*  Tris(1,3-dichloro-2-propyl)phosphate
... phosphate in Sprague-Dawley rat". International Journal of Toxicology. 19 (13674): 119-125. California Office of Environmental ... in the rat". Toxicology and Applied Pharmacology. 57 (3): 401-13. doi:10.1016/0041-008X(81)90238-6. ISSN 0041-008X. PMID ... and excretion of flame retardants halogenated alkyl phosphate in rats". Eisei Kagaku. 34 (2): 102-114. doi:10.1248/jhs1956.34. ...
*  Reduced muscle mass, strength and performance in space
... is somewhat different from the more selective Type I myofiber atrophy observed in unloaded Sprague-Dawley and Wistar rat muscle ... The center of gravity in rats is much lower than normal. They no longer support their body weight and initiate movement off the ... To our knowledge the only other species besides the rat that has been involved in spaceflight studies on skeletal muscle is the ... McDonald, KS; Delp, MD; Fitts, RH (June 1992). "Effect of hindlimb unweighting on tissue blood flow in the rat". Journal of ...