Mann, Margaret C. (1922). Observations on an Inbred Strain of Drosophila Melanogaster. University of California. University of ... Mann, Margaret (1918). Division in the Unfertilized Egg of the Rat. University of California. ...
Mouse strains can be inbred, mutated, or genetically modified, while rat strains are usually inbred. A given inbred rodent ... Coli Genetic Stock Center EcoliWiki E. coli strain index International Mouse Strain Resource (IMSR) Rat strain index (Articles ... A laboratory mouse or rat strain is a group of animals that is genetically uniform. Strains are used in laboratory experiments ... In biology, a strain is a genetic variant, a subtype or a culture within a biological species. Strains are often seen as ...
Inbred and outbred mouse and rat strains have very different susceptibility to Sendai virus infection. Visualization of SeV ... All Sendai virus strains belong to the same serotype. The origin of many strains of SeV was described in 1978. Some strains ... Another strain is Tianjin strain, isolated in China in 2008. One of these strains was used for creation of replication ... It is reported that the BB1 strain derived from the Moscow virus strain. The strain BB1 was given to the researchers of ...
... and later to the common use of inbred rats by experimental psychologists." Wistar as a generic name for inbred strains such as ... Such strains are useful in the analysis of variance within an inbred strain or between inbred strains because any differences ... "History of inbred strains". isogenic.info. Retrieved 2017-11-30. Dixon LK (1993). "Use of recombinant inbred strains to map ... "History of inbred strains". Retrieved 2013-12-19. "History of inbred strains". isogenic.info. Retrieved 2017-11-30. Kirchmaier ...
Systematic inbreeding and maintenance of inbred strains of laboratory mice and rats is of great importance for biomedical ... 2006). "Selection and Inbreeding Depression: Effects of Inbreeding Rate and Inbreeding Environment". Evolution. 60 (5): 1014- ... The use of inbred strains is also important for genetic studies in animal models, for example to distinguish genetic from ... In order to achieve a mouse strain that is considered inbred, a minimum of 20 sequential generations of sibling matings must ...
Other factors that make the species a desirable test subject are the existence of inbred strains, ease of handling, and ... The tawny-bellied cotton rat occurs in the same area as the closely related hispid cotton rat, with the former occupying the ... Cotton rats combine the best traits of human-like lung granuloma formation (trait of rabbits) and inexpensive care (trait of ... The tawny-bellied cotton rat is used as a model organism to develop and test human pathogen treatments. It is affected by many ...
... of the WAG/Rij inbred rat strain: a classical mendelian crossbreeding study". Behavior Genetics. 22 (3): 361-8. doi:10.1007/ ... van Luijtelaar ELJM; van der Staay FJ; Kerbusch JML (August 1989). "Spatial memory in rats: a cross validation study". The ... Peeters BWMM; Kerbusch JML; van Luijtelaar ELJM; Vossen JMH; Coenen AML (May 1990). "Genetics of absence epilepsy in rats". ...
NCLAS also came into the limelight due to the WNIN/Ob obese rat strain which is the heaviest inbred rat model available. It has ... The scientists of NCLAS Developed obese and diabetic mutant rat models: WNIN/GR-Ob, WNIN/Ob, WNIN/Ob-IGT, to serve as pre- ... K. S. Jayaraman (2005). "'Sumo' rats set researchers on hunt for obesity genes". Nature Medicine. 11 (2): 108. doi:10.1038/ ... a novel rat model of premature aging". Neuroscience. 269: 256-264. doi:10.1016/j.neuroscience.2014.03.040. PMID 24709042. S2CID ...
... , also known as the BB or BBDP rat, is an inbred laboratory rat strain that spontaneously develops autoimmune ... 12 and 14 have been shown to be linked to Type 1 Diabetes in the BB rat. BB rats are the most extensively studied rat model of ... Like the NOD mice, BB rats are used as an animal model for Type 1 diabetes. The strain re-capitulates many of the features of ... Subsequent BB rat colonies were established. One in Worcester, Massachusetts, has been inbred and known as BBDP/Wor and another ...
Familiar albino animals include in-bred strains of laboratory animals (rats, mice and rabbits), but populations of naturally ... Examples include the BALB/c mouse and Wistar and Sprague Dawley rat strains, laboratory rabbits and ferrets. Some researchers ... rats, guinea pigs and cats. Examples of pet mammals artificially selected for albinism Intentionally bred albinistic strains of ... The Okinawa strain of this species is deficient in [His7]-corazonin and is albino. One of the typical features of Locusta ...
... of emotionality in rats and his discovery that a single dominant gene led to acoustical traumas in one inbred strain of mice". ... This work extended his mentor Tryon's earlier rat demonstration that they could be bred to do well or poorly in learning a maze ...
Festing, M., "Inbred Strains of Mice and their Characteristics", The Jackson Laboratory . Retrieved 30 January 2008. Peichel CL ... Rats are also widely used for physiology, toxicology and cancer research, but genetic manipulation is much harder in rats than ... Laboratory mice, flies, fish, and worms are inbred through many generations to create strains with defined characteristics. ... and rats are all widely used. Studies of brain function, such as memory and social behavior, often use rats and birds. For some ...
The biobreeding rat (a.k.a. the biobreeding diabetes-prone rat or BBDP rat) is an inbred strain that spontaneously develops ... "Rat Genome", Nature Rat Genome Database, Medical College of Wisconsin Index of Inbred Rat Strains database, Jacskson Laboratory ... Holtzman albino strains, Long-Evans, and Lister black hooded rats. Inbred strains are also available, but are not as commonly ... and these rats are usually referred to as "stocks" rather than "strains". The Wistar rat is an outbred albino rat. This breed ...
Schwartz WJ, Zimmerman P. Circadian timekeeping in BALB/c and C57BL/6 inbred mouse strains. J Neurosci. 1990; 10: 3685-3694. ... They found in albino rats that Fos has altered immunoreactive levels in a phase-dependent manner when exposed to light. This ... Sumová A, Trávnícková Z, Peters R, Schwartz WJ, Illnerová H. The rat suprachiasmatic nucleus is a clock for all seasons. Proc ... Light regulates expression of a Fos-related protein in rat suprachiasmatic nuclei. Proc Natl Acad Sci USA. 1990; 87: 5959-5962 ...
Between 2005 and 2007, virtually all extant mouse and rat recombinant inbred strains were regenotyped at many thousands of SNP ... Recombinant inbred strains or lines were first developed using inbred strains of mice but are now used to study a wide range of ... In the case of a typical mouse recombinant inbred strain made by crossing maternal strain BALB/cBy (C) with paternal strain ... pairs of the F2 progeny are then mated to establish inbred strains through long-term inbreeding. Families of recombinant inbred ...
... strains are generated in the laboratory by mating two inbred strains (usually rats or mice), and back-crossing the ... Congenic mice or rats can then be compared to the pure recipient strain to determine whether they are phenotypically different ... Congenic strains are discussed in detail in Lee Silver's online book Mouse Genetics: Concepts and Applications: "Mouse Genetics ... November 1997). "Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains". Nat. Genet. 17 (3): ...
... rats, inbred strains MeSH B01.050.157.760.080 - rats, inbred aci MeSH B01.050.157.760.090 - rats, inbred bb MeSH B01.050. ... rats, inbred strains MeSH B01.050.199.520.760.080 - rats, inbred aci MeSH B01.050.199.520.760.090 - rats, inbred bb MeSH ... rats, inbred f344 MeSH B01.050.157.760.275 - rats, inbred lec MeSH B01.050.157.760.280 - rats, inbred lew MeSH B01.050.157.760. ... rats, inbred shr MeSH B01.050.157.760.360 - rats, inbred wf MeSH B01.050.157.760.390 - rats, inbred wky MeSH B01.050.199.040 - ...
... a dimensionless number in fluid dynamics and transport phenomena Lewis rat, an inbred strain of laboratory rat Lewis (TV series ...
"Inbred Strain - an overview , ScienceDirect Topics". Silver, L. (2001). "Inbred Strain". Brenner's Encyclopedia of Genetics. p ... "MGI-Guidelines for Nomenclature of Mouse and Rat Strains". www.informatics.jax.org. "Outbred stocks". 15 February 2019. Crow JF ... "000646 - AJ Strain Details". "002105 - New Zealand Obese Strain Details". "000928 - CAST Strain Details". "003715 - Strain ... "000658 - C3HFe Strain Details". "001976 - NOD Strain Details". "000670 - DBA1 Strain Details". "001026 - Strain Details". " ...
In 1999, they showed that different inbred strains of mice displayed very different pain sensitivity. Chief among these ... Quenqua, Douglas (2014-04-28). "For Lab Rats, a 'Male Scientist' Effect". The New York Times. ISSN 0362-4331. Retrieved 2020-07 ... Responses of 11 inbred mouse strains on 12 measures of nociception". Pain. 80 (1): 67-82. doi:10.1016/s0304-3959(98)00197-3. ... "Genetic sensitivity to hot-plate nociception in DBA/2J and C57BL/6J inbred mouse strains: possible sex-specific mediation by δ2 ...
Many inbred strains exist, as well as lines selected for particular traits, often of ethological or medical interest, e.g. body ... Sigmodon hispidus (Cotton rat), formerly used in polio research. Mesocricetus auratus (Golden hamster), first used to study ... Main lab strain is 'K-12'. Bacillus subtilis, endospore forming Gram-positive bacterium. Main lab strain is '168'. Caulobacter ... Pseudomonas fluorescens, soil bacterium that readily diversifies into different strains in the lab. Azotobacter vinelandii, ...
These initial observations led to the development of two breeding colonies: (i) a fully inbred strain of rats, with 100% of ... The development of two inbred strains from the same initial colony has appeared as a very powerful tool to study the possible ... a strain of non epileptic control animals selected from the same initial breeding colony of Wistar rats and called the Non ... Since then, the GAERS has been recognized as a very predictive model for absence epilepsy, along with the WAG/Rij rat model. ...
In 2004, Hornig published a controversial paper concluding that, in a highly inbred strain of mice which is unusually ... based on neonatal rat infection with Borna disease virus. ... Neurotoxic effects of postnatal thimerosal are mouse strain ... Hornig M, Chian D, Lipkin WI (September 2004). "Neurotoxic effects of postnatal thimerosal are mouse strain dependent". Mol. ... Davis were unable to reproduce Hornig's results despite using the same strain of mice and ten times the amount of mercury used ...
... inbred mouse strain and the systematic generation of other inbred strains. The mouse has since been used extensively as a model ... supported Mouse Repository Rat Resource & Research Center - National Institutes of Health, supported Rat Repository NIH Model ... In addition, inbred mouse strains are used in the overwhelming majority of studies, while the human population is heterogeneous ... The classic model vertebrate is currently the mouse (Mus musculus). Many inbred strains exist, as well as lines selected for ...
Effects of Aspiculuris tetraptera and Syphacia obvelata on exploratory behaviour of an inbred mouse strain. Laboratory Animal ... An example of this behaviour is the attraction of rats to cat urine after infection with Toxoplasma gondii. However, the " ... Berdoy, M.F., Webster, J. P & MacDonald, D. W. (2000) Fatal Attraction in rats infected with Toxoplasma gondii. Proceedings of ...
In mice, large differences in learning ability exist among different inbred strains. These differences appear to be correlated ... As a result, the rat always has eight possible options. Elaborate controls are used to ensure that the rats are not simply ... Working memory is assessed when the rats enter each arm a single time. Re-entry into the arms would result in a working memory ... The design ensures that, after checking for food at the end of each arm, the rat is always forced to return to the central ...
West, D. B.; Boozer, C. N.; Moody, D. L.; Atkinson, R. L. (1992-06-01). "Dietary obesity in nine inbred mouse strains". The ... Rats have also been used in the diet-induced obesity model. Commonly used in medical research, rats were specifically chosen to ... Furthermore, the strain and sex of the rodent impacts the response to the model. Some common mouse strains show large ... This has led to cases of studies that used the same strain of mice concluding that the strain is prone to becoming obese in one ...
Weber M, Swerdlow NR (January 2008). "Rat strain differences in startle gating-disruptive effects of apomorphine occur with ... Paylor R, Crawley JN (July 1997). "Inbred strain differences in prepulse inhibition of the mouse startle response". ... The baseline startle response does not affect overall PPI levels - this finding was first discovered in rat studies and later ... ISBN 978-0-444-50676-4. Wu MF, Krueger J, Ison JR, Gerrard RL (April 1984). "Startle reflex inhibition in the rat: its ...
The availability of inbred and mutant mouse strains can be advantageous when examining the genetic basis of murine ... N. brasiliensis is adapted to infecting rats, so can continue laying eggs for prolonged periods of time. The immune response of ... Biphasic anorexia is also prevalent in laboratory rats infected with this parasite. The first phase coincides with the ... Tetramisole loaded into zeolite is more effective at killing adults of N. brasiliensis in rats than tetramisole alone. ...
Differences in Glo1 expression in mice appear to be caused by a copy number variant that is common among inbred strains of mice ... Experiments on three types of glyoxalase I (yeast, rat and mouse forms) supported the proton-transfer mechanism in every case. ... "Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains". ...