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*  Congenic
... strains are generated in the laboratory by mating two inbred strains (usually rats or mice), and back-crossing the ... Congenic mice or rats can then be compared to the pure recipient strain to determine whether they are phenotypically different ... Congenic strains are discussed in detail in Lee Silver's online book Mouse Genetics: Concepts and Applications: "Mouse Genetics ... November 1997). "Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains". Nat. Genet. 17 (3): ...
*  List of MeSH codes (B01)
... rats, inbred strains MeSH B01.050.157.760.080 --- rats, inbred aci MeSH B01.050.157.760.090 --- rats, inbred bb MeSH B01.050. ... rats, inbred strains MeSH B01.050.199.520.760.080 --- rats, inbred aci MeSH B01.050.199.520.760.090 --- rats, inbred bb MeSH ... rats, inbred buf MeSH B01.050.157.760.165 --- rats, inbred dahl MeSH B01.050.157.760.200 --- rats, inbred f344 MeSH B01.050. ... rats, inbred lew MeSH B01.050.157.760.290 --- rats, inbred oletf MeSH B01.050.157.760.300 --- rats, inbred shr MeSH B01.050. ...
*  Lewis (disambiguation)
... in fluid dynamics and transport phenomena Lewis rat, an inbred strain of laboratory rat Lewis structure, a diagram of a ...
*  GAERS
These initial observations led to the development of two breeding colonies: (i) a fully inbred strain of rats, with 100% of ... The development of two inbred strains from the same initial colony has appeared as a very powerful tool to study the possible ... a strain of non epileptic control animals selected from the same initial breeding colony of Wistar rats and called the NEC. ... Since then, the GAERS has been recognized as a very predictive model for Absence Epilepsy, along with the WAG/Rij rat model. ...
*  Sjeng Kerbusch
... of the WAG/Rij inbred rat strain: a classical mendelian crossbreeding study". Behavior Genetics. 22 (3): 361-8. doi:10.1007/ ... van Luijtelaar ELJM; van der Staay FJ; Kerbusch JML (August 1989). "Spatial memory in rats: a cross validation study". The ... Peeters BWMM; Kerbusch JML; van Luijtelaar ELJM; Vossen JMH; Coenen AML (May 1990). "Genetics of absence epilepsy in rats". ...
*  Tawny-bellied cotton rat
Other factors that make the species a desirable test subject are the existence of inbred strains, ease of handling, and ... The tawny-bellied cotton rat occurs in the same area as the closely related hispid cotton rat, with the former occupying the ... Cotton rats combine the best traits of human-like lung granuloma formation (trait of rabbits) and inexpensive care (trait of ... The tawny-bellied cotton rat is used as a model organism to develop and test human pathogen treatments. It is affected by many ...
*  Laboratory rat
Rat Genome Rat Genome Database Charles River Laboratories Harlan Sprague Dawley Jax Index of Inbred Rat Strains Knock Out Rat ... Biobreeding diabetes-prone rat (a.k.a. biobreeding rat or BBDP rat) is an inbred strain that spontaneously develops autoimmune ... A laboratory rat or lab rat is a rat of the species Rattus norvegicus (brown rat) which is bred and kept for scientific ... The Sprague Dawley rat and Long-Evans rats were developed from Wistar rats. Wistar rats are more active than others like ...
*  Strain (biology)
Strains are used in laboratory experiments. Mouse strains can be inbred, mutated or genetically engineered, while rat strains ... Coli Genetic Stock Center EcoliWiki E. coli strain index International Mouse Strain Resource (IMSR) Rat strain index. ... A mouse or a rat strain is a group of animals that is genetically uniform. ... The rice plants in the strain can be bred to other rice strains or cultivars, and if desirable plants are produced, these are ...
*  Calvin S. Hall
... of emotionality in rats and his discovery that a single dominant gene led to acoustical traumas in one inbred strain of mice". ... This work extended his mentor Tryon's earlier rat demonstration that they could be bred to do well or poorly in learning a maze ...
*  Albinism in biology
Familiar albino animals include in-bred strains of laboratory animals (rats, mice, guinea-pigs and rabbits), but populations of ... Examples include the BALB/c mouse and Wistar and Sprague Dawley rat strains, laboratory rabbits, guinea-pigs and ferrets. ... rats, guinea pigs and cats. Examples of pet mammals artificially selected for albinism Intentionally bred albinistic strains of ... The Okinawa strain of this species is deficient in [His7]-corazonin and is albino. One of the typical features of Locusta ...
*  Inbred strain
"History of inbred strains". Retrieved 2013-12-19. "Rat strains". isogenic.info. Retrieved 2017-11-30. "History of inbred ... Such strains are useful in the analysis of variance within an inbred strain or between inbred strains because any differences ... use Backcrossing Linebreeding Recombinant inbred strain Coisogenic strain Congenic strain Inbreeding depression Inbreeding ... "History of inbred strains". isogenic.info. Retrieved 2017-11-30. Dixon LK (1993). "Use of recombinant inbred strains to map ...
*  Biobreeding rat
... also known as the BB or BBDP rat is an inbred laboratory rat strain that spontaneously develops autoimmune Type ... 12 and 14 have been shown to be linked to Type 1 Diabetes in the BB rat. BB rats are the most extensively studied rat model of ... Like the NOD mice, BB rats are used as an animal model for Type 1 diabetes. The strain re-capitulates many of the features of ... Subsequent BB rat colonies were established. One in Worcester, Massachusetts, has been inbred and known as BBDP/Wor and another ...
*  Recombinant inbred strain
Between 2005 and 2007, virtually all extant mouse and rat recombinant inbred strains were regenotyped at many thousands of SNP ... Recombinant inbred strains or lines were first developed using inbred strains of mice but are now used to study a wide range of ... In the case of a typical mouse recombinant inbred strain made by crossing maternal strain BALB/cBy (C) with paternal strain ... pairs of the F2 progeny are then mated to establish inbred strains through long-term inbreeding. Families of recombinant inbred ...
*  National Institute of Nutrition, Hyderabad
NCLAS also came into the limelight due to the WNIN/Ob obese rat strain which is the heaviest inbred rat model available. It has ... Developed obese and diabetic mutant rat models: WNIN/GR-Ob, WNIN/Ob, WNIN/Ob-IGT, to serve as pre-clinical animal models in ... K. S. Jayaraman (2005). "'Sumo' rats set researchers on hunt for obesity genes". Nature Medicine. 11 (2): 108. doi:10.1038/ ... a novel rat model of premature aging". Neuroscience. 269: 256-64. doi:10.1016/j.neuroscience.2014.03.040. PMID 24709042. "New ...
*  List of model organisms
Many inbred strains exist, as well as lines selected for particular traits, often of medical interest, e.g. body size, obesity ... Cotton rat (Sigmodon hispidus) - formerly used in polio research. Dog (Canis lupus familiaris) - an important respiratory and ... Pseudomonas fluorescens, a soil bacterium that readily diversifies into different strains in the lab. Azotobacter vinelandii, a ... Quantitative genetics, Molecular evolution, Genomics) Naked mole-rat, (Heterocephalus glaber), studied for their characteristic ...
*  William J. Schwartz
Schwartz WJ, Zimmerman P. Circadian timekeeping in BALB/c and C57BL/6 inbred mouse strains. J Neurosci. 1990; 10: 3685-3694. ... They found in albino rats that Fos has altered immunoreactive levels in a phase-dependent manner when exposed to light. This ... Sumová A, Trávnícková Z, Peters R, Schwartz WJ, Illnerová H. The rat suprachiasmatic nucleus is a clock for all seasons. Proc ... Light regulates expression of a Fos-related protein in rat suprachiasmatic nuclei. Proc Natl Acad Sci USA. 1990; 87: 5959-5962 ...
*  Mady Hornig
In 2004, Hornig published a controversial paper concluding that, in a highly inbred strain of mice which is unusually ... based on neonatal rat infection with Borna disease virus. ... Neurotoxic effects of postnatal thimerosal are mouse strain ... Hornig M, Chian D, Lipkin WI (September 2004). "Neurotoxic effects of postnatal thimerosal are mouse strain dependent". Mol. ... Davis were unable to reproduce Hornig's results despite using the same strain of mice and ten times the amount of mercury used ...
*  Laboratory mouse
... inbred mouse strain and initiated the systematic generation of inbred strains. The mouse has since been used extensively as a ... "Rules and guidelines for nomenclature of mouse and rat strains". "Outbred stocks". Crow JF (August 2002). "C. C. Little, cancer ... There are hundreds of established inbred, outbred, and transgenic strains. A strain, in reference to rodents, is a group in ... Many (but not all) laboratory strains are inbred. The different strains are identified with specific letter-digit combinations ...
*  Diet-induced obesity model
West, D. B.; Boozer, C. N.; Moody, D. L.; Atkinson, R. L. (1992-06-01). "Dietary obesity in nine inbred mouse strains". The ... Rats have also been used in the diet-induced obesity model. Commonly used in medical research, rats were specifically chosen to ... Furthermore, the strain and sex of the rodent impacts the response to the model. Some common mouse strains show large ... This has led to cases of studies that used the same strain of mice concluding that the strain is prone to becoming obese in one ...
*  Obligate parasite
Effects of Aspiculuris tetraptera and Syphacia obvelata on exploratory behaviour of an inbred mouse strain. Laboratory Animal ... An example of this behaviour is the attraction of rats to cat urine after infection with Toxoplasma gondii. In some cases the ... Berdoy, M.F., Webster, J. P & MacDonald, D. W. (2000) Fatal Attraction in rats infected with Toxoplasma gondii. Proceedings of ...
*  Model organism
... inbred mouse strain and the systematic generation of other inbred strains. The mouse has since been used extensively as a model ... The rat (Rattus norvegicus) is particularly useful as a toxicology model, and as a neurological model and source of primary ... The classic model vertebrate is currently the mouse (Mus musculus). Many inbred strains exist, as well as lines selected for ... This usually will include characteristics such as short life-cycle, techniques for genetic manipulation (inbred strains, stem ...
*  Prepulse inhibition
Weber, M; Swerdlow, N (2008). "Rat strain differences in startle gating-disruptive effects of apomorphine occur with both ... Paylor, R; Crawley, Jacqueline N (1997). "Inbred strain differences in prepulse inhibition of the mouse startle response". ... Baseline startle response does not affect overall PPI levels - this finding was first discovered in rat studies and later ... Possible hearing impairment must be taken into account, as, for example, several strains of mice develop high frequency hearing ...
*  Radial arm maze
In mice, large differences in learning ability exist among different inbred strains. These differences appear to be correlated ... As a result, the rat always has eight possible options. Elaborate controls are used to ensure that the rats are not simply ... Working memory is assessed when the rats enter each arm a single time. Re-entry into the arms would result in a working memory ... The design ensures that, after checking for food at the end of each arm, the rat is always forced to return to the central ...
*  Nippostrongylus brasiliensis
The availability of inbred and mutant mouse strains can be advantageous when examining the genetic basis of murine ... N. brasiliensis are adapted to infecting rats and so can continue laying eggs for prolonged periods of time. The immune ... Biphasic anorexia is also prevalent in laboratory rats infected with this parasite. The first phase coincides with the ... Anorexia in rats infected with the nematode, Nippostrongylus brasiliensis: experimental manipulations. Parasitology 120:641-647 ...
*  Lactoylglutathione lyase
Differences in Glo1 expression in mice appear to be caused by a copy number variant that is common among inbred strains of mice ... Experiments on three types of glyoxalase I (yeast, rat and mouse forms) supported the proton-transfer mechanism in every case. ... "Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains". ...
*  Andrew Wakefield
"Monocyte/macrophage procoagulant activity as a measure of immune responsiveness in Lewis and brown Norway inbred rats. ... and wild strains of the aforementioned viruses) results in ileal lymphoid nodular hyperplasia, chronic colitis and pervasive ...