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After the confirmation of lysosome, de Duve's team was troubled by the presence (in the rat liver cell fraction) of the enzyme ... Among other subjects, he studied the distribution of enzymes in rat liver cells using rate-zonal centrifugation. His work on ... I. The existence of a mitochondria-linked, enzymically inactive form of acid phosphatase in rat-liver tissue". The Biochemical ... The nature of the linkage between acid phosphatase and mitochondria in rat-liver tissue". The Biochemical Journal. 50 (2): 182- ...
Moyle and Mitchell isolated rat liver mitochondria to investigate their hypothesis that the calcium transporter is in fact a ... Moyle, Jennifer; Mitchell, Peter (1977). "The lanthanide-sensitive calcium phosphate porter of rat liver mitochondria". FEBS ... Mitchell, Peter; Moyle, Jennifer (December 1967). "Respiration-driven proton translocation in rat liver mitochondria". ... symporter that is insensitive to NEM and mersalyl catalyzed calcium translocation in the mitochondria of the rat liver. ...
Acid phosphatase Liver function tests PDB: 1ALK​: Kim EE, Wyckoff HW (March 1991). "Reaction mechanism of alkaline phosphatase ... Intestinal alkaline phosphatase (IAP) and the mechanism it uses to regulate pH and ATP hydrolysis in rat duodenum. Testing the ... However, the human liver enzyme and the placental enzyme only share 20% homology despite their structural similarities. ... "Alkaline phosphatase: Liver Function Test - Viral Hepatitis". www.hepatitis.va.gov. Retrieved 2016-05-02. Delmas PD (December ...
4-COT becomes covalently bound to DNA of rats and mice livers. Inhalation or skin contact with 4-COT produces acute toxic ... Toxicol., 1987, 2, 326-356 Bentley P. et al., Species differences in the toxicity of p-chloro-o-toluidine to rats and mice. ...
The researchers then incorporated the bioreactor into a rat model, connecting rats with induced liver failure to the system and ... 2005). "Outcome from molecular adsorbent recycling system (MARS) liver dialysis following drug-induced liver failure". Liver ... bioartificial liver device). This system is in trial to help people with acute liver failure (ALF) or acute-on-chronic liver ... either allowing the liver to regenerate properly upon acute liver failure, or to bridge the individual's liver functions until ...
Liver Physiol., 289 (5): 815-821, doi:10.1152/ajpgi.00001.2005, PMID 16020659. Amberg, G.C.; Santana, L.F. (2006), "Kv2 ... 2005) and enhances myogenic constriction in (rat) cerebral arteries (Amberg et al. 2006). No toxic effects of stromatoxin have ... "Kv2 subunits underlie slowly inactivating potassium current in rat neocortical pyramidal neurons", J. Physiol., 581 (3): 941- ... channels oppose myogenic constriction of rat cerebral arteries", Am. J. Physiol. Cell Physiol., 291 (2): 348-356, doi:10.1152/ ...
It became apparent that exenatide reduced liver fat in mice, rat and more recently in man. In 2016 work published showing that ... Exenatide reduces liver fat content. Fat accumulation in the liver or nonalcoholic fatty liver disease (NAFLD) is strongly ... Eli Lilly has stated the drug causes an increase in thyroid problems in rats given high doses. In March 2013, the FDA issued a ... Exenatide also suppresses pancreatic release of glucagon in response to eating, which helps stop the liver from overproducing ...
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Laperche, Yannick; Oudea, Marie-Claire; Lostanlen, Danielle (1977). "Toxic effects of indocyanine green on rat liver ... ICG is metabolized microsomally in the liver and only excreted via the liver and bile ducts; since it is not absorbed by the ... The intravenous LD50 values measured in animals are 60 mg/kg in mice and 87 mg/kg in rats. Occasionally - in one out of 42,000 ... ICG has a half-life of 150 to 180 seconds and is removed from circulation exclusively by the liver to bile. ICG is a ...
I. Purification and properties of the rat liver enzyme". Biochemistry. 9 (6): 1403-15. doi:10.1021/bi00808a015. PMID 4313883. ...
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Cook RJ, Wagner C (1984). "Glycine N-methyltransferase is a folate binding protein of rat liver cytosol". Proceedings of the ... The properties of GNMT protein from rabbits, rats and humans, either purified from liver/pancreas, or expressed in Escherichia ... Raha A, Wagner C, MacDonald RG, Bresnick E (1994). "Rat liver cytosolic 4 S polycyclic aromatic hydrocarbon-binding protein is ... Ogawa H, Fujioka M (1982). "Purification and properties of glycine N-methyltransferase from rat liver". The Journal of ...
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ApoB mRNA editing also occurs in mice, and rats. In contrast to humans editing occurs in liver in mice and rats up to a ... Baum CL, Teng BB, Davidson NO (November 1990). "Apolipoprotein B messenger RNA editing in the rat liver. Modulation by fasting ... The first is synthesized exclusively by the small intestine, the second by the liver. ApoB-100 is the largest of the apoB group ... The main function of the full length liver expressed ApoB100 is as a ligand for activation of the LDL-R. However, editing ...
Schlame M, Rüstow B (December 1990). "Lysocardiolipin formation and reacylation in isolated rat liver mitochondria". The ... in rat heart mitochondria. In 2003, the same lab purified and characterized an MLCL acyltransferase in pig liver mitochondria, ... MLCL AT-1 activity also increases in a rat model of spontaneously hypertensive heart failure. Since cardiolipin content is ... Ma BJ, Taylor WA, Dolinsky VW, Hatch GM (October 1999). "Acylation of monolysocardiolipin in rat heart". Journal of Lipid ...