"CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in ... and gamma subunit immunoreceptor tyrosine-based activation motif in signaling of myeloid high affinity Fc receptor for IgG (Fc ... Rap guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the RAPGEF1 gene. The protein encoded by ... Ehrhardt A, Ehrhardt GR, Guo X, Schrader JW (Oct 2002). "Ras and relatives--job sharing and networking keep an old family ...

TRIM24 Tripartite motif-containing 24 (TRIM24) TRIM28 Tripartite motif-containing 28 (TRIM28) TRIM33 Tripartite motif- ... Vadlamudi RK, Wang RA, Mazumdar A, Kim Y, Shin J, Sahin A, Kumar R (2001). "Molecular cloning and characterization of PELP1, a ... "The coregulator exchange in transcriptional functions of nuclear receptors". Genes Dev. 14 (2): 121-41. doi:10.1101/gad.14.2. ... The LXXLL binding motifs have been shown by X-ray crystallography to bind to a groove on the surface of ligand binding domain ...

It is only partially preserved and has been restored as gud-dam iriki [...], originally possibly gud-dam iriki ba-ra-è, "Gudam ... However, he did tentatively voice support for the proposal that he might be related to the well-attested motif in Mesopotamian ... offering to bring her cattle and sheep from the mountains in exchange. The final section of the story is poorly preserved, ... as it constitutes a reversal of the well attested motif of a mother praising a victorious protagonist, and that his status will ...

The SNARE motifs form a four-helix bundle that contributes to the fusion of two membranes. More specifically, the N-terminal ... This is the way cell cargo is exchanged. This particular entry focuses on the N-terminal domain of Syntaxin 6. Members of this ... Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (April 1996). "A "double adaptor" method for improved shotgun library ... Their exact function has not been determined, though it is known that they regulate the SNARE motif, as well as mediate various ...

A large variety of decorations and motifs are attested. This pottery is very similar to certain types of the Mycenaean pottery ... "Cypriote Imports at Ras Shamra," Israel Exploration Journal 31 1981 Artzy, M., Asaro, F., and Perlman, I., 1973, The origin of ... Exchange and Politico-Economic Change, Monographs in World Archaeology 21, Prehistory Press, Madison, Wisconsin Merrillees, R.S ... many types of pottery previously believed to have originated in Ras Shamra-Ugarit, now in Syria, had actually been made in ...

Hall RA, Ostedgaard LS, Premont RT, Blitzer JT, Rahman N, Welsh MJ, Lefkowitz RJ (July 1998). "A C-terminal motif found in the ... and RACK1 binding to Na+/H+ exchange regulatory factor". The Journal of Biological Chemistry. 277 (25): 22925-22933. doi: ... The amino-terminus is part of the lasso motif which anchors into the cell membrane. The carboxyl terminal of the protein is ... Zhang H, Peters KW, Sun F, Marino CR, Lang J, Burgoyne RD, Frizzell RA (August 2002). "Cysteine string protein interacts with ...

The motif is a venerable mythic motif, the interrupted message, and raises the question of what would have happened if only, if ... Based on these exchanges, Larsen concludes that Frazer's deliberate use of Judeo-Christian terminology in the place of native ... But the rat god, Ra Kalavo, would not permit this, insisting that men should die like rats. In Australia, the Wotjobaluk ... This Bura story has the common mythic motif of a vital message which is diverted by a trickster. In Togoland, the messengers ...

"Tacita Dean RA". Royal Academy of the Arts. Retrieved 6 March 2017. Tacita Dean, Julie Mehretu, June 8 - July 20, 2018 Marian ... In 2000, Dean was awarded a one-year German Academic Exchange Service (DAAD) scholarship to Berlin, where she moved that year ... exploiting the metaphorical richness of such motifs as the ocean, lighthouses and shipwrecks. Re-turning to her attraction with ... Tacita Charlotte Dean CBE, RA (born 1965) is a British visual artist who works primarily in film. She was a nominee for the ...

An LXXLL signature motif is present within the SAP domain of all PIAS proteins. This signature motif has been shown to mediate ... Klopocki E, Schulze H, Strauss G, Ott CE, Hall J, Trotier F, Fleischhauer S, Greenhalgh L, Newbury-Ecob RA, Neumann LM, ... Glass CK, Rosenfeld MG (Jan 2000). "The coregulator exchange in transcriptional functions of nuclear receptors". Genes & ... The LXXLL motif represents the minimal requirement for the interaction with the NFκB p65 subunit and for the inhibition of NFκB ...

Duke-Cohan JS, Kang H, Liu H, Rudd CE (May 2006). "Regulation and function of SKAP-55 non-canonical motif binding to the SH3c ... Additional work has implicated SKAP1 in binding to the exchange factor RasGRP1 and in regulating ERK activation in T-cells. ... "SKAP55 modulates T cell antigen receptor-induced activation of the Ras-Erk-AP1 pathway by binding RasGRP1". Molecular ... "SH3 domain recognition of a proline-independent tyrosine-based RKxxYxxY motif in immune cell adaptor SKAP55". The EMBO Journal ...

Eukaryotic Linear Motif resource motif class TRG_Cilium_Arf4_1 This article incorporates text from the public domain Pfam and ... Kahn RA, Kern FG, Clark J, Gelmann EP, Rulka C (1991). "Human ADP-ribosylation factors. A functionally conserved family of GTP- ... ARFs regularly associate with two types of protein, those involved in catalyzing GTP/GDP exchange, and those that serve other ... Boman AL, Kahn RA; Kahn (1995). "Arf proteins: The membrane traffic police?". Trends in Biochemical Sciences. 20 (4): 147-150. ...

Ng C, Jackson RA, Buschdorf JP, Sun Q, Guy GR, Sivaraman J (Mar 2008). "Structural basis for a novel intrapeptidyl H-bond and ... Hu J, Hubbard SR (2005). "Structural characterization of a novel Cbl phosphotyrosine recognition motif in the APS family of ... Yabana N, Shibuya M (2002). "Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange ...

LIPs contain an NPM-motif in place of the second conserved NPA-motif typical of the majority of MIPs. Aquaporins have been ... Parisi M, Dorr RA, Ozu M, Toriano R (December 2007). "From membrane pores to aquaporins: 50 years measuring water fluxes". J ... Paganelli CV, Solomon AK (November 1957). "The rate of exchange of tritiated water across the human red cell membrane". J. Gen ... from the two sides of the NPA motif. Its usual position is 8 Å on the outer side of the NPA motif; it is typically the tightest ...

Ras gene - Ras protein - reading frame - receptor (biochemistry) - receptor antagonist - receptor protein-tyrosine kinase - ... sequence motif - sequencing - serine - serotonin - serotonin receptor - serpin - sexual reproduction - SH3 domain - SI - sigma ... hydrogen-deuterium exchange - hydrolysis - hydrolytic enzyme - hydrophilic - hydrophobe - hydrophobic - hydrophobicity analysis ... structural motif - substance P - substrate - sugar - sulfur - supercoil - superfamily - superoxide - surface immunoglobulin - ...

The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) ... Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-scale ... Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 ... Meacci E, Tsai SC, Adamik R, Moss J, Vaughan M (1997). "Cytohesin-1, a cytosolic guanine nucleotide-exchange protein for ADP- ...

Some methods can capture the signal recorded in motifs of variable size, thus capturing both rare and discriminative motifs ... Nelson KE, Clayton RA, Gill SR, Gwinn ML, Dodson RJ, Haft DH, et al. (May 1999). "Evidence for lateral gene transfer between ... For example, it has been shown that horizontal transfer between closely related species results in more exchange of ORF ... Welch RA, Burland V, Plunkett G, Redford P, Roesch P, Rasko D, et al. (December 2002). "Extensive mosaic structure revealed by ...

Churchill JD, Bowne SJ, Sullivan LS, Lewis RA, Wheaton DK, Birch DG, et al. (February 2013). "Mutations in the X-linked ... The C-terminal domain of the RPGRconst isoform contains a CTIL motif (812CTIL815) which recruits prenyl-binding protein PDE6D ... characteristic of the highly conserved guanine nucleotide exchange factors. Mutations in this gene have been associated with X- ... Glomset JA, Farnsworth CC (1994). "Role of protein modification reactions in programming interactions between ras-related ...

The ligand exchange mechanism allows for faster exchange than a diffusion mechanism and imparts specificity for both the metal ... The metal binding motif is largely solvent exposed in Apo-ATOX1 and a conformational change is induced upon coordination to Cu( ... Alvarez HM, Xue Y, Robinson CD, Canalizo-Hernández MA, Marvin RG, Kelly RA, Mondragón A, Penner-Hahn JE, O'Halloran TV (Jan ... Since the ligand exchange accelerates that transfer and the reaction has a shallow thermodynamic gradient, it is said to be ...

... including highly stylized plant and animal motifs such as resting birds, gazelles, and cheetahs. Other motifs are undoubtedly ... The product of this hunt may have been exchanged for plant products cultivated further north. Primarily for food, it is also ... Some sites, such as Hadji Muhammed and Ras al Amiya, were discovered by accident during modern construction. In the desert ... These motifs can also represent men, women, birds, fish, antelopes, or scorpions. Some necklaces even have reliefs of human ...

Kahn RA, Kern FG, Clark J, Gelmann EP, Rulka C (1991). "Human ADP-ribosylation factors. A functionally conserved family of GTP- ... ARF4 has been shown to interact with Epidermal growth factor receptor and with RVxP motifs. GRCh38: Ensembl release 89: ... with members of the cytohesin family of guanine nucleotide exchange factors". J. Biol. Chem. 275 (22): 16827-36. doi:10.1074/ ... Lebeda RA, Haun RS (1999). "Cloning and characterization of the human ADP-ribosylation factor 4 gene". Gene. 237 (1): 209-14. ...

The activated Gα subunit exchanges GTP in place of GDP which in turn triggers the dissociation of Gα subunit from the Gβγ dimer ... Characteristic motifs indicate that three of the five GRAFS families, Rhodopsin, Adhesion, and Frizzled, evolved from the ... Smith JS, Nicholson LT, Suwanpradid J, Glenn RA, Knape NM, Alagesan P, et al. (November 2018). "Biased agonists of the ... The cell maintains a 10:1 ratio of cytosolic GTP:GDP so exchange for GTP is ensured. At this point, the subunits of the G- ...

... RA (born 1965) is a British painter. Anderson is a British born painter. He focuses his artwork on telling ... This double-sided heritage informs many of the motifs often expressed in Anderson's work. He experiments with the markers of ... New Art Exchange, Nottingham (2016) Backdrop, CAM, St. Louis (2015) Reporting Back, Ikon Gallery, Birmingham (2013) Subtitles, ... While recent works, such as Studio Drawing 15 (2016) mark a shift toward abstraction in his oeuvre, the motifs of the ...

Bednar J, Horowitz RA, Grigoryev SA, Carruthers LM, Hansen JC, Koster AJ, Woodcock CL (November 1998). "Nucleosomes, linker DNA ... Cytoplasmic factors appear to be necessary for the dynamic exchange of histone H1 on chromatin, but these have yet to be ... In addition, experiments on reconstituted chromatin reveal a characteristic stem motif at the dyad in the presence of H1. ... Steinbach OC, Wolffe AP, Rupp RA (September 1997). "Somatic linker histones cause loss of mesodermal competence in Xenopus". ...

A dynamic exchange of partners". J. Biol. Chem. 278 (41): 39265-8. doi:10.1074/jbc.C300098200. PMID 12930846. Gulbis JM, Kelman ... Serrano M, Hannon GJ, Beach D (December 1993). "A new regulatory motif in cell-cycle control causing specific inhibition of ... Watanabe H, Pan ZQ, Schreiber-Agus N, DePinho RA, Hurwitz J, Xiong Y (February 1998). "Suppression of cell transformation by ... Many proteins interact with PCNA via the two known PCNA-interacting motifs PCNA-interacting peptide (PIP) box and AlkB ...

MKK7 has three conserved D-motifs (MAPK-recruiting short linear motifs) on its intrinsically disordered N-terminus. D-motifs ... Foltz IN, Gerl RE, Wieler JS, Luckach M, Salmon RA, Schrader JW (April 1998). "Human mitogen-activated protein kinase kinase 7 ... Jaffe AB, Hall A, Schmidt A (March 2005). "Association of CNK1 with Rho guanine nucleotide exchange factors controls signaling ... that specifically recognize their cognate D-motifs. The D-motifs found in MKK7 are highly specific for JNKs, but have a ...

"RA Exchange" podcast with Martyn, and an official Ableton session with Ellie Herring. The Cambridge-based makerspace Danger ... Marimba - Two Pat Fontes - Hudson House Pizza TECHNCN - Turning Point Adam Noya - Back Up Dumka - Motif Fuzzy Fotch - Yo Cut ... "Together Festival 2016: Five key performances · Event Review ⟋ RA". Reed, James (7 February 2010). "Putting it all Together". ... "Together Boston 2014 · Event Review ⟋ RA". "The Boston Calendar Best of Awards -- #BestInBoston". "Together Festival: How ...

The motif SDGGGX2DX2R is present in all RDR interference group members within this conserved region and may play an important ... Sommerfelt MA, Weiss RA (May 1990). "Receptor interference groups of 20 retroviruses plating on human cells". Virology. 176 (1 ... The placental barrier enables nutrient and waste exchange, while blocking maternal immune and other cells, particles and ... The two subunits form a heterodimer and are likely linked by a disulfide bond between two conserved cysteine rich motifs: CXXC ...

These two HKD motifs confer hydrolytic activity to PLD, and are critical for its enzymatic activity both in vitro and in vivo. ... These small monomeric GTPases are members of the Rho and ARF families of the Ras superfamily. Some of these proteins, such as ... Strictly speaking, phospholipase D is a transphosphatidylase: it mediates the exchange of polar headgroups covalently attached ... The active site of PLDs consists of four highly conserved amino acid sequences (I-IV), of which motifs II and IV are ...

Philibert RA, Ryu GY, Yoon JG, Sandhu H, Hollenbeck N, Gunter T, Barkhurst A, Adams W, Madan A (Jul 2007). "Transcriptional ... AAA_11 and AAA_12 contain a P-loop motif which are involved in conjugative transfer proteins. Other helicase domains are also ... Mechanistically, ZGRF1 physically interacts with the RAD51 recombinase and stimulates strand exchange by RAD51-RAD54. ZGRF1 ... These paralogs operate under a SPF1 RNA helicase motif. Mov10, a paralog, and probable RNA helicase is required for RNA- ...

In this common motif, MAPK is activated by an earlier kinase in the cascade, called MAPK kinase, or MAPKK. Similarly, MAPKK is ... The transition between the active and inactive states is facilitated by guanine nucleotide exchange factors (GEFs) and GTPase ... such as Ran and Ras, can exist in either a GTP-bound form (active) or a GDP-bound form (inactive), and the conversion between ... A ubiquitous signaling motif that exhibits ultrasensitivity is the MAPK (mitogen-activated protein kinase) cascade, which can ...

Clark KL, Halay ED, Lai E, Burley SK (July 1993). "Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles ... including FoxO3 and FoxM that repress the cell survival pathways Ras and PPI3K/AKT/IKK. Drugs such as Paclitaxel, Imatinib, and ... "Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism". Cell. 146 (4): 544- ...