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*  RALA
"Identification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from ... "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of ... "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of ... Wang KL, Roufogalis BD (May 1999). "Ca2+/calmodulin stimulates GTP binding to the ras-related protein ral-A". The Journal of ...
*  RALB
... v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)". Simicek M, Lievens S, Laga M, Guzenko ... "Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of ... Ras-related protein Ral-B (RalB) is a protein that in humans is encoded by the RALB gene on chromosome 2. This protein is one ... Hsieh CL, Swaroop A, Francke U (1990). "Chromosomal localization and cDNA sequence of human ralB, a GTP binding protein". Somat ...
*  RRAS
"The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene. 21 ( ... Yu Y, Feig LA (2002). "Involvement of R-Ras and Ral GTPases in estrogen-independent proliferation of breast cancer cells". ... "The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1". Oncogene. 21 ( ... Ras-related protein R-Ras is a protein that in humans is encoded by the RRAS gene. RRAS has been shown to interact with: ARAF, ...
*  Paracrine signalling
In turn, the intermediate protein stimulates GDP-bound Ras to the activated GTP-bound Ras. GAP eventually returns Ras to its ... and Ral pathway. Each pathway leads to the activation of transcription factors which enter the nucleus to alter gene expression ... Wnt proteins binds to its transmembrane receptor of the Frizzled family of proteins. The binding of Wnt to a Frizzled protein ... The BMPs bind to the bone morphogenetic protein receptor type II (BMPR2). Some of the proteins of the BMP family are BMP4 and ...
*  Alan Hall
Ral-dependent branching implicated the phosphorylation of growth-associated protein GAP-43. Finally, Ral mutants unable to bind ... In 1993, Alan Hall was awarded the Feldberg Foundation Prize for his work on the role GTP-binding proteins played on signal ... In parallel with this experiment, Hall showed that the presence of Rac, another Ras-related GTP-binding protein, is implicated ... Ridley, Anne; Hall, Alan (7 August 1992). "The small GTP-binding protein rho regulates the assembly of focal adhesions and ...
*  Small GTPase
A typical G-protein is active when bound to GTP and inactive when bound to GDP (i.e. when the GTP is hydrolyzed to GDP). The ... Ral, Rit, Rap, Rheb, and Rad. Miro is a recent contributor to the superfamily. Each subfamily shares the common core G domain, ... GTP-binding protein regulators Wennerberg K, Rossman KL, Der CJ (March 2005). "The Ras superfamily at a glance". J. Cell Sci. ... Therefore, a G-protein can be switched on and off. GTP hydrolysis is accelerated by GTPase activating proteins (GAPs), while ...
*  List of MeSH codes (D08)
... ral gtp-binding proteins MeSH D08.811.277.040.330.300.400.462 --- ran gtp-binding protein MeSH D08.811.277.040.330.300.400.475 ... gtp-binding protein alpha subunit, gi2 MeSH D08.811.277.040.330.300.200.100.300 --- gtp-binding protein alpha subunits, gq-g11 ... gtp-binding protein alpha subunits, g12-g13 MeSH D08.811.277.040.330.300.200.100.200 --- gtp-binding protein alpha subunits, gi ... rab gtp-binding proteins MeSH D08.811.277.040.330.300.400.400.025 --- rab1 gtp-binding proteins MeSH D08.811.277.040.330.300. ...
*  List of MeSH codes (D12.776.476)
... rac gtp-binding proteins MeSH D12.776.476.525.700.100.100 -- rac1 gtp-binding protein MeSH D12.776.476.525.700.200 -- rhoa gtp- ... proto-oncogene proteins c-vav MeSH D12.776.476.325.300.600 -- ral guanine nucleotide exchange factor MeSH D12.776.476.325. ... rab1 gtp-binding proteins MeSH D12.776.476.525.400.050 -- rab2 gtp-binding protein MeSH D12.776.476.525.400.100 -- rab3 gtp- ... rab3a gtp-binding protein MeSH D12.776.476.525.400.150 -- rab4 gtp-binding proteins MeSH D12.776.476.525.400.200 -- rab5 gtp- ...
*  RAPGEF2
... is a cyclic AMP binding protein. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP- ... Spaargaren M, Bischoff JR (December 1994). "Identification of the guanine nucleotide dissociation stimulator for Ral as a ... 1999). "nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding ... serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between ...
*  Phospholipase D1
... and Rho family monomeric GTP-binding proteins and protein kinase C-alpha". J. Biol. Chem. 272 (6): 3860-8. doi:10.1074/jbc. ... Suzuki J, Yamazaki Y, Li G, Kaziro Y, Koide H, Guang L (2000). "Involvement of Ras and Ral in chemotactic migration of skeletal ... Hughes WE, Parker PJ (2001). "Endosomal localization of phospholipase D 1a and 1b is defined by the C-termini of the proteins, ... Bae CD, Min DS, Fleming IN, Exton JH (1998). "Determination of interaction sites on the small G protein RhoA for phospholipase ...
*  List of MeSH codes (D12.776.157)
... rab4 gtp-binding proteins MeSH D12.776.157.325.515.400.200 -- rab5 gtp-binding proteins MeSH D12.776.157.325.515.450 -- ral gtp ... ran gtp-binding protein MeSH D12.776.157.325.515.475 -- rap gtp-binding proteins MeSH D12.776.157.325.515.475.100 -- rap1 gtp- ... gtp-binding protein alpha subunits, g12-g13 MeSH D12.776.157.325.332.100.200 -- gtp-binding protein alpha subunits, gi-go MeSH ... gtp-binding protein alpha subunit, gi2 MeSH D12.776.157.325.332.100.300 -- gtp-binding protein alpha subunits, gq-g11 MeSH ...
*  List of MeSH codes (D12.644)
... rab5 gtp-binding proteins MeSH D12.644.360.525.450 --- ral gtp-binding proteins MeSH D12.644.360.525.462 --- ran gtp-binding ... rab gtp-binding proteins MeSH D12.644.360.525.400.025 --- rab1 gtp-binding proteins MeSH D12.644.360.525.400.050 --- rab2 gtp- ... rac1 gtp-binding protein MeSH D12.644.360.525.700.200 --- rhoa gtp-binding protein MeSH D12.644.360.525.700.300 --- rhob gtp- ... rap gtp-binding proteins MeSH D12.644.360.525.475.100 --- rap1 gtp-binding proteins MeSH D12.644.360.525.500 --- ras proteins ...
*  EXOC4
"Exocyst complex subunit sec8 binds to postsynaptic density protein-95 (PSD-95): a novel interaction regulated by cypin ( ... Brymora A, Valova VA, Larsen MR, Roufogalis BD, Robinson PJ (2001). "The brain exocyst complex interacts with RalA in a GTP- ... Polzin A, Shipitsin M, Goi T, Feig LA, Turner TJ (2002). "Ral-GTPase influences the regulation of the readily releasable pool ... The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting ...
*  KRAS
... binds GTP present in the cytosol and the GEF is released from ras-GTP. Other members of the Ras family include: HRAS and ... KRAS can bind to proteins of the Guanine Nucleotide Exchange Factor (GEF) class (such as SOS1), which forces the release of ... Spaargaren M, Bischoff JR (December 1994). "Identification of the guanine nucleotide dissociation stimulator for Ral as a ... KRAS binds to GTP in its active state. It also possesses an intrinsic enzymatic activity which cleaves the terminal phosphate ...