Quisqualic acid
Being a 3, 5 disubstituted oxadiazole, quisqualic acid is a stable compound. One way of synthesizing quisqualic acid is by ... L-quisqualic acid, was isolated. Quisqualic acid is functionally similar to glutamate, which is an endogenous agonist of ... the overactivation of these receptors by quisqualic acid can suggest a potential role in movement disorders. Quisqualic acid is ... Quisqualic acid is thought to mimic L-glutamic acid, which is a neurotransmitter in the insect neuromuscular junction and ...
Ibotenic acid
Conotoxin Grayanotoxin Quisqualic acid Tetrodotoxin "Ibotenic acid". pubchem.ncbi.nlm.nih.gov. Stebelska, Katarzyna (August ... Ibotenic acid or (S)-2-amino-2-(3-hydroxyisoxazol-5-yl)acetic acid, also referred to as ibotenate, is a chemical compound and ... At least some ingested ibotenic acid is likely decarboxylated into muscimol so some of the effects of ingesting ibotenic acid ... The reaction yields threo-3-hydroxyglutamic acid, which is converted into ibotenic acid, likely by enzymes encoded in the ...
Cysteine synthase
"Enzymatic-synthesis of the neuroexcitatory amino-acid quisqualic by cysteine synthase". Phytochemistry. 25 (12): 2759-2763. doi ... This enzyme participates in 3 metabolic pathways: cysteine metabolism, selenoamino acid metabolism, and sulfur metabolism. It ...
Ligand-gated ion channel
Ligands include: Agonists: Glutamate, AMPA, 5-Fluorowillardiine, Domoic acid, Quisqualic acid, etc. Antagonists: CNQX, ... aminocyclopropanecarboxylic acid; D-cycloserine; L-aspartate; quinolinate, etc. Partial agonists : N-methyl-D-aspartic acid ( ... Honoré T, Lauridsen J, Krogsgaard-Larsen P (January 1982). "The binding of [3H]AMPA, a structural analogue of glutamic acid, to ... The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (also known as AMPA receptor, or quisqualate receptor) is a ...
Quisqualamine
... α-Decarboxylation of excitatory amino acids can produce derivatives with inhibitory effects. Indeed, unlike quisqualic acid, ... Quisqualic acid Muscimol Evans RH, Francis AA, Hunt K, Martin MR, Watkins JC (June 1978). "Quisqualamine, a novel gamma- ... Whether it binds to and acts upon any of the metabotropic glutamate receptors like its analogue quisqualic acid however is ... Quisqualamine is the α-decarboxylated analogue of quisqualic acid, as well as a relative of the neurotransmitters glutamate and ...
Combretaceae
Many plants in the former Quisqualis genus contain the excitotoxin quisqualic acid, a potent AMPA agonist. The family name ...
Metabotropic glutamate receptor
... are stimulated most strongly by the excitatory amino acid analog L-quisqualic acid. Stimulating the receptors causes the ... L-quisqualic acid and recombinant receptors" (subscription required). Zeitschrift für Naturforschung C. 57 (3-4): 348-55. doi: ... Like all glutamate receptors, mGluRs bind with glutamate, an amino acid that functions as an excitatory neurotransmitter. The ... Gabriel L, Lvov A, Orthodoxou D, Rittenhouse AR, Kobertz WR, Melikian HE (September 2012). "The acid-sensitive, anesthetic- ...
Non-proteinogenic amino acids
... including quisqualic acid, canavanine and azetidine-2-carboxylic acid.Cephalosporin C has an α-aminoadipic acid (homoglutamate ... ic acid.) Most natural amino acids are α-amino acids in the L conformation, but some exceptions exist. Some non-α-amino acids ... Thialysine quisqualic acid canavanine azetidine-2-carboxylic acid cephalosporin C penicillamine Naturally-occurring cyanotoxins ... Chemically synthesized amino acids can be called unnatural amino acids. Unnatural amino acids can be synthetically prepared ...
Convulsant
AMPA Domoic acid Kainic acid NMDA Quinolinic acid Quisqualic acid Tetrazolylglycine Acetylcholine receptor agonists are drugs ... For example, kainic acid can lead to status epilepticus in animals as it is a cyclic analog of l-glutamate and an agonist for ... "Kainic Acid - an overview , ScienceDirect Topics". www.sciencedirect.com. Retrieved 2022-01-15. "GABA-A Receptor Antagonists - ... 3-Mercaptopropionic acid Allylglycine Glycine receptor antagonists are drugs which inactivates the glycine receptors. ...
Domoic acid
Canadian Reference Materials Pseudo-nitzschia Quisqualic acid Brevetoxin Ciguatoxin Okadaic acid Saxitoxin Maitotoxin Clayden J ... Domoic acid (DA) is a kainic acid-type neurotoxin that causes amnesic shellfish poisoning (ASP). It is produced by algae and ... In addition domoic acid was used to poison a witness in the Elementary Season 1 Episode 13: "The Red Team". Domoic acid ... Domoic acid is an excitatory amino acid analogue of glutamate; a neurotransmitter in the brain that activates glutamate ...
Metabotropic glutamate receptor 4
Hermit MB, Greenwood JR, Bräuner-Osborne H (Aug 2004). "Mutation-induced quisqualic acid and ibotenic acid affinity at the ... Cinnabarinic acid, a tryptophan metabolite LSP1-2111: agonist LSP4-2022: agonist LSP2-9166: mixed agonist at mGluR4 and mGluR7 ... "Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors". ... metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues". The ...
Combretum indicum
... contain the chemical quisqualic acid, which is an agonist for the AMPA receptor, a kind of glutamate receptor in the brain. The ...
C4H7N3O3
... the α-decarboxylated analogue of quisqualic acid This set index page lists chemical structure articles associated with the same ...
Excitatory amino acid receptor agonist
Examples include: AMPA Glutamic acid Ibotenic acid Kainic acid N-Methyl-D-aspartic acid Quisqualic acid Excitatory amino acid ... Amino acids, Excitatory amino acid receptor agonists, All stub articles, Nervous system drug stubs). ... An excitatory amino acid receptor agonist, or glutamate receptor agonist, is a chemical substance which agonizes one or more of ... receptor antagonist Excitatory amino acid reuptake inhibitor Excitatory+amino+acid+agonists at the U.S. National Library of ...
AMPA receptor
... the endogenous agonist Ibotenic acid - a naturally occurring agonist found in Amanita muscaria Quisqualic acid - a naturally ... A 38-amino acid sequence found prior to (i.e., before the N-terminus of) the fourth membranous domain in all four AMPAR ... Decanoic acid and the AMPA receptor antagonist drug perampanel act at separate sites on the AMPA receptor, and so it is ... While the amino acid sequence of the subunit indicated that there seemed to be four transmembrane domains (parts of the protein ...
List of MeSH codes (D03)
... quisqualic acid MeSH D03.383.129.462.580.693 - sydnones MeSH D03.383.129.462.580.693.450 - molsidomine MeSH D03.383.129.462.600 ... pipemidic acid MeSH D03.383.725.547.650 - piromidic acid MeSH D03.383.725.547.900 - 3-pyridinecarboxylic acid, 1,4-dihydro-2,6- ... niflumic acid MeSH D03.066.515.635 - pipemidic acid MeSH D03.066.515.650 - piromidic acid MeSH D03.066.515.950 - xanthinol ... nalidixic acid MeSH D03.438.810.835.055.550 - nedocromil MeSH D03.438.810.835.055.580 - oxolinic acid MeSH D03.438.810.835.188 ...
Plant defense against herbivory
The geranium, for example, produces the amino acid, quisqualic acid in its petals to defend itself from Japanese beetles. ... Oxalyldiaminopropionic acid is a neurotoxic amino acid produced as a defensive metabolite in the grass pea (Lathyrus sativus). ... In addition, some plants use fatty acid derivatives, amino acids and even peptides as defenses. The cholinergic toxin, ... The tree cells respond by increasing the concentration of salicylic acid (hormone) production. Salicylic acid is a phytohormone ...