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*  Quantitative structure-activity relationship
Some examples are quantitative structure-reactivity relationships (QSRRs), quantitative structure-chromatography relationships ... QSCRs) and, quantitative structure-toxicity relationships (QSTRs), quantitative structure-electrochemistry relationships (QSERs ... one can find a mathematical relationship, or quantitative structure-activity relationship, between the two. The mathematical ... While many quantitative structure activity relationship analyses involve the interactions of a family of molecules with an ...
*  5-MeO-DET
Quantitative Structure-Activity Relationships. 18 (6): 548-560. doi:10.1002/(SICI)1521-3838(199912)18:6. 3.0.CO;2-B. Michael B ... P.K. Gessner; D.D. Godse; A.H. Krull; J.M. McMullan (March 1968). "Structure-activity relationships among 5-methoxy-N:N- ...
*  Partition coefficient
"Atomic Physicochemical Parameters for Three-Dimensional Structure-Directed Quantitative Structure-Activity Relationships I. ... Quantitative Structure-Activity Relationships. 7 (3): 133-144. doi:10.1002/qsar.19880070304. Andrés A, Rosés M, Ràfols C, Bosch ... "Use of distribution coefficients in quantitative structure-activity relationships". (primary). Journal of Medicinal Chemistry. ... ISBN 978-3-906390-22-2. Martin YC (2010). "Chapter 4: The Hydrophobic Properties of Molecules". Quantitative Drug Design: A ...
*  Dinoseb
Dinoterb Topliss, John (2012-12-02). Quantitative Structure-Activity Relationships of Drugs. Elsevier. p. 427. ISBN ... 2-(1-methylpropyl)phenol takes up the nitronium ion to form the arenium ion, which has three resonance structures. Water can ... This compound had a superior contact and stomach activity on insects and mites. Dinoseb became commercially available in 1945 ...
*  2,5-Dimethoxy-4-isopropylamphetamine
Analysis by quantitative structure-activity relationships". ACS Symposium Series. 413: 264-280. doi:10.1021/bk-1989-0413.ch018 ... "Structure-activity relations in psychotomimetic phenylalkylamines". Journal of Medicinal Chemistry. 17 (10): 1100-1111. doi: ... "A structure-affinity study of the binding of 4-substituted analogs of 1-(2,5-dimethoxyphenyl)-2-aminopropane at 5-HT2 serotonin ...
*  Adenine phosphoribosyltransferase
Liu Q, Hirono S, Moriguchi I (Aug 1990). "Quantitative structure-activity relationships for calmodulin inhibitors". Chemical & ... However, a recent effort to resolve the structure of human APRTase was unable to locate a single site for Mg2+, but did find ... Type I deficiency results in a complete loss of APRTase activity and can occur in patients that are homozygous or compound ... It is treatable with regular doses of allopurinol or febuxostat, which inhibit xanthine dehydrogenase activity to prevent the ...
*  Indane
Synthesis, activities, and analysis of quantitative structure-activity relationships". Journal of Medicinal Chemistry. 33 (9): ...
*  4-Fluoromethylphenidate
"Quantitative structure-activity relationship studies of threo-methylphenidate analogs". Bioorganic & Medicinal Chemistry. 18 ( ... 2. StructureActivity Relationship Studies of Aromatic Ring-Substituted Methylphenidate Analogs". Journal of Medicinal ... Satendra Singh (February 2000). "Chemistry, Design, and StructureActivity Relationship of Cocaine Antagonists". Chemical ...
*  Therapeutic Targets Database
Dudek AZ, Arodz T, Gálvez J (2006). "Computational methods in developing quantitative structure-activity relationships (QSAR): ... and reduced resistance activities by simultaneously modulating the activity of a primary target and the counteractive elements ... 3D structure, ligand binding properties, enzyme nomenclature and drug structure, therapeutic class, clinical development status ... 20 microM regardless of their possible activities against other targets. These multi-target agents can be retrieved from Multi- ...
*  Grunwald-Winstein equation
Free-energy relationship Hammett equation Quantitative structure-activity relationship Eric Anslyn, E.; Dougherty, D. A. Modern ... This relationship can be visualized through a Hammett Plot. However, if the solvent of the reaction is changed, but not the ... For many reactions and nucleophilic solvent systems, the relationships are not fully linear. This derives from the growing SN2 ... The Hammett equation (Equation 1) provides the relationship between the substituent on the benzene ring and the ionizing rate ...
*  Molecular Informatics
... quantitative structure-activity relationships, and combinatorial chemistry. It was established in 1981 as Quantitative ... Structure-Activity Relationships and renamed to QSAR & Combinatorial Science in 2003, before obtaining its present name in 2010 ...
*  Pesticide degradation
In the absence of such rate constants, quantitative structure-activity relationships(QSARs) may allow their estimation for a ... Canonica, S; Tratnyek, P. G. (2003). "Quantitative structure-activity relationships for oxidation reactions of organic ... Thus, although molecular structure generally predicts intrinsic reactivity, quantitative predictions are limited. ... A complementary, potentially more quantitative technique is to directly enumerate the biodegradative gene(s) via quantitative ...
*  Taft equation
Free-energy relationship Hammett equation Quantitative structure-activity relationship Eric Anslyn, E.; Dougherty, D. A. Modern ... organic chemistry in the study of reaction mechanisms and in the development of quantitative structure activity relationships ... employed in biological chemistry and medicinal chemistry for the development of quantitative structure activity relationships ( ... The Taft equation is a linear free energy relationship (LFER) used in physical ...
*  Sean Ekins
2002). "Quantitative structure activity relationships for the glucuronidation of simple phenols by expressed human UGT1A6 and ... 1999). "Three dimensional-quantitative structure activity relationship analyses of substrates for CYP2B6". Pharm Exp Ther. 288 ... 2002). "Three dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein". Mol Pharmacol. 61: ... Ekins, G. Wikel J.H.; Bravi, S.; Wrighton, SA (1999). "Three dimensional quantitative structure activity relationship (3D-QSAR ...
*  Biological aspects of fluorine
Gabriel, J. L.; Miller, T. F.; Wolfson, M. R. Jr; Shaffer, T. H. (1996). "Quantitative structure-activity relationships of ... ISBN 0-13-033451-0. Danielson, Mark A.; Falke, Joseph J. (1996). "Use of 19F NMR to probe protein structure and conformational ... PFC concentrations were generally higher in areas with more human population or industrial activity, and areas with more PFOS ... Fluorine-19 is commonly used in NMR study of metabolism, protein structures and conformational changes. In addition, inert ...
*  Corwin Hansch
Quantitative Structure Activity Relationships (QSAR). Fragment based regression analysis for quantitative structure-activity ... Hansch may be best known as the father of the concept of quantitative structure-activity relationship (QSAR), the quantitative ... Hansch Analysis - Hansch analysis is the investigation of the quantitative relationship between the biological activity of a ... relationship (Hansch-analysis) He died of pneumonia on May 8, 2011 in Claremont, California at 92. His research group at Pomona ...
*  Poly(amidoamine)
Towards quantitative structure activity relationships". Toxicology in Vitro. 24 (1): 169-77. doi:10.1016/j.tiv.2009.09.014. ... The fragmentation of some branches of the dendrimer is thought to loosen up the overall structure (fewer amide bonds and space ... The tertiary amines on the interior of the dendrimer can also participate in the buffering activity, causing the molecule to ... Influence of polymer structure on cell viability and hemolysis". Biomaterials. 24 (7): 1121-31. doi:10.1016/S0142-9612(02)00445 ...
*  Fish acute toxicity syndrome
In toxicology, the quantitative structure-activity relationship (QSAR) approach is a method for predicting toxicity based on ... For instance, FATS data is used to develop quantitative structure-activity relationship (QSAR) models. QSAR models developed ... Netzeva TI, Pavan M, Worth AP (January 2008). "Review of (Quantitative) Structure-Activity Relationships for Acute Aquatic ... Based on the QSAR approach, differences in the chemical structure can be used to predict the activity of toxicants. The ...
*  Copper in health
... quantitative structure-activity relationships". Journal of Inorganic Biochemistry. 77 (3-4): 125-33. doi:10.1016/S0162-0134(99) ... "Synthesis and structure-activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives ... Reduced lysyl oxidase activity results in defective collagen and elastin polymerization and corresponding connective-tissue ... The study of copper's genetic diseases, which are the focus of intense international research activity, has shed insight into ...
*  Metabotropic glutamate receptor 2
"Investigation on quantitative structure activity relationships and pharmacophore modeling of a series of mGluR2 antagonists". ... robust in-vivo activity. LY-487,379: devoid of orthosteric activity; along with related 3-pyridylmethylsulfonamides the first ... Due to this, lisuride is capable of reducing the hallucinogenic effects of these drugs through competitive agonistic activity ( ... frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s)". Psychopharmacology. 179 (1 ...
*  Alkenal
"Quantitative structure-activity relationship for 4-hydroxy-2-alkenal induced cytotoxicity in L6 muscle cells". Chemico- ...
*  Iodoacetic acid
Richard, Ann M.; Hunter, E. Sidney, III (1996). "Quantitative Structure-Activity Relationships for the Developmental Toxicity ... In 1966 Charles A. Apffel, Barry G. Arnason & John H. Peters showed anti-tumor activity for iodoacetate. Iodide is a naturally ... Fahim, F. A.; Esmat, A. Y.; Mady, E. A.; Ibrahim, E. K. (2003). "Antitumor Activities of Iodoacetate and Dimethylsulphoxide ... activity, while it also significantly decreased the levels of plasma glucose and liver total protein, RNA and DNA, compared to ...
*  SULT1A3
Molecular modeling and quantitative structure-activity relationship analysis demonstrate a molecular basis for sulfotransferase ... The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase ... 1999). "Crystal structure of human catecholamine sulfotransferase". J. Mol. Biol. 293 (3): 521-30. doi:10.1006/jmbi.1999.3153. ... Bernier F, Leblanc G, Labrie F, Luu-The V (1994). "Structure of human estrogen and aryl sulfotransferase gene. Two mRNA species ...
*  Spinosad
... biochemistry and quantitative structure-activity relationships of spinosyns and spinosoids". pest manag sci. 57. ,access-date= ... The apparent lack of spinosyn A metabolism may contribute to its high level of activity, and may compensate for the slow rate ... Spinosad is a mixture of chemical compounds in the spinosyn family that has a generalized structure consisting of a unique ... of the insect nervous system that are distinct from those at which other insecticides have their activity. Spinosoid binding ...
*  Chemist
... and their quantitative structure-activity relationships. Organic chemistry is the study of the structure, properties, ... Analytical chemistry is the analysis of material samples to gain an understanding of their chemical composition and structure. ... Inorganic chemistry is also the study of atomic and molecular structure and bonding. Medicinal chemistry is the science ... working under the guidance of senior chemists in a research-oriented activity), or, alternatively, they may work on distinct ( ...
*  Human geography
... the latter concentrating upon the study of human activities, by the application of qualitative and quantitative research ... Economic geography examines relationships between human economic systems, states, and other factors, and the biophysical ... Palm, Risa (2016-09-05). "Urban geography: city structures". Progress in Geography. doi:10.1177/030913258200600104. Kaplan, ... These are areas where the majority of economic activities are in the secondary sector and tertiary sectors. In case of urban ...