... , also known as pyruvate dehydrogenase E1 component subunit beta, mitochondrial or PDHE1 ... Mutations in the PDHB gene have been known to cause one form of pyruvate dehydrogenase deficiency. Pyruvate dehydrogenase ... Korotchkina LG, Patel MS (Feb 2008). "Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex ... Korotchkina LG, Patel MS (Feb 2008). "Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex ...

... , also known as pyruvate dehydrogenase E1 component subunit alpha, testis-specific ... Mutations in the PDHA2 gene have been known to cause one form of pyruvate dehydrogenase deficiency. Pyruvate dehydrogenase ... "Entrez Gene: pyruvate dehydrogenase (lipoamide) alpha 2". Dahl HH, Brown RM, Hutchison WM, Maragos C, Brown GK (October 1990 ... The pyruvate dehydrogenase complex is responsible for the oxidative decarboxylation of pyruvate, with the final product being ...

Mutations in the PDHA1 gene have been known to cause one form of pyruvate dehydrogenase deficiency. Pyruvate dehydrogenase ... "Entrez Gene: PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1". Maragos C, Hutchison WM, Hayasaka K, Brown GK, Dahl HH (Jul ... The pyruvate dehydrogenase complex is responsible for the oxidative decarboxylation of pyruvate, with the final product being ... Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial is an enzyme that in humans is encoded by the ...

It codes for an isozyme of pyruvate dehydrogenase kinase (PDK). Pyruvate dehydrogenase (PDH) is a part of a mitochondrial ... Pyruvate dehydrogenase lipoamide kinase isozyme 1, mitochondrial is an enzyme that in humans is encoded by the PDK1 gene. ... of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase". J. ... of pyruvate dehydrogenase kinase and the inner lipoyl-bearing domain of transacetylase component of pyruvate dehydrogenase ...

Pyruvate dehydrogenase lipoamide kinase isozyme 3, mitochondrial is an enzyme that in humans is encoded by the PDK3 gene. It ... "Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex". The ... "Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex". The ... codes for an isozyme of pyruvate dehydrogenase kinase.The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded ...

... is an enzyme that catalyzes the reaction of pyruvate and a lipoamide to give the acetylated ... Pyruvate dehydrogenase is usually encountered as a component, referred to as E1, of the pyruvate dehydrogenase complex (PDC). ... Human proteins that possess pyruvate dehydrogenase activity include: In bacteria, a form of pyruvate dehydrogenase (also called ... PDBe-KB provides an overview of all the structure information available in the PDB for Human pyruvate dehydrogenase (lipoamide ...

Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial (PDK4) is an enzyme that in humans is encoded by the PDK4 gene ... of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase". The ... of pyruvate dehydrogenase kinase and the inner lipoyl-bearing domain of transacetylase component of pyruvate dehydrogenase ... The pyruvate dehydrogenase (PDH) complex must be tightly regulated due to its central role in general metabolism. Within the ...

... pyruvate dehydrogenase (lipoamide)]-phosphatase, and [pyruvate dehydrogenase (lipoamide)]-phosphate phosphohydrolase. As of ... pyruvate dehydrogenase (acetyl-transferring)]-phosphatase (EC 3.1.3.43) catalyzes the reaction [pyruvate dehydrogenase (acetyl- ... Other names in common use include pyruvate dehydrogenase phosphatase, phosphopyruvate dehydrogenase phosphatase, [ ... Reed LJ, Damuni Z, Merryfield ML (1985). "Regulation of mammalian pyruvate and branched-chain α-keto acid dehydrogenase ...

Pyruvate dehydrogenase kinase isoform 2 (PDK2) also known as pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial ... of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase". The ... of pyruvate dehydrogenase kinase and the inner lipoyl-bearing domain of transacetylase component of pyruvate dehydrogenase ... The Pyruvate Dehydrogenase (PDH) complex must be tightly regulated due to its central role in general metabolism. Within the ...

... pyruvate dehydrogenase (lipoamide) MeSH D08.811.682.657.350.937 - pyruvate oxidase MeSH D08.811.682.657.350.968 - pyruvate ... pyruvate dehydrogenase (lipoamide)-phosphatase MeSH D08.811.277.352.650.700 - 6-phytase MeSH D08.811.277.352.650.850 - pten ... pyruvate dehydrogenase (lipoamide) MeSH D08.811.600.850 - sucrase-isomaltase complex MeSH D08.811.600.896 - tryptophan synthase ... dihydrolipoamide dehydrogenase MeSH D08.811.682.657.350.760 - 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) MeSH D08.811. ...

... alpha 1 Protocadherin alpha 1 Pulmonary surfactant-associated protein A1 Pyruvate dehydrogenase (lipoamide) alpha 1 RNA binding ... alpha 1 Aldehyde dehydrogenase 3 family, member A1 Aldehyde dehydrogenase 4 family, member A1 Aldehyde dehydrogenase 5 family, ... member A1 Aldehyde dehydrogenase 6 family, member A1 Aldehyde dehydrogenase 9 family, member A1 Aldehyde dehydrogenase 18 ... an actin-binding protein NADH dehydrogenase (ubiquinone), alpha 1 Nucleolar protein, member A1 PCDHA4 Phospholipase A1 ...

... pyruvate dehydrogenase (lipoamide) MeSH D05.500.562.750 - succinate cytochrome c oxidoreductase MeSH D05.500.562.750.249 - ... pyruvate dehydrogenase complex MeSH D05.500.562.625.500 - dihydrolipoamide dehydrogenase MeSH D05.500.562.625.750 - ... glycine dehydrogenase (decarboxylating) MeSH D05.500.562.468 - ketoglutarate dehydrogenase complex MeSH D05.500.562.468.500 - ... dihydrolipoamide dehydrogenase MeSH D05.500.562.452.175 - glycine decarboxylase complex h-protein MeSH D05.500.562.452.200 - ...

"The refined crystal STRUCTURE of pseudomonas Putida LIPOAMIDE DEHYDROGENASE complexed with NAD+ at 2.45 Å resolution". Proteins ... The reaction catalysed by pyruvate dehydrogenase complex is: The E1 subunit, called the pyruvate dehydrogenase subunit, has a ... In eukaryotes PDC is tightly regulated by its own specific pyruvate dehydrogenase kinase (PDK) and pyruvate dehydrogenase ... "How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase ...

Lipoamide is subsequently used as a cofactor for α-ketoglutarate dehydrogenase, the pyruvate dehydrogenase complex, and ... Dihydrolipoamide is a molecule oxidized by dihydrolipoyl dehydrogenase in order to produce lipoamide. ... branched-chain α-ketoacid dehydrogenase complex. Dihydrolipoic acid Lipoic acid Nomenclature of Organic Chemistry : IUPAC ...

Pyruvate dehydrogenase (lipoamide) alpha 1 Pyruvate dehydrogenase (lipoamide) alpha 2 Pyruvate dehydrogenase (lipoamide) beta ... Pyruvate dehydrogenase is a type of enzyme. Pyruvate dehydrogenase may also refer to: Pyruvate dehydrogenase (cytochrome) ... Pyruvate dehydrogenase (NADP+) This disambiguation page lists articles associated with the title Pyruvate dehydrogenase. If an ...

For example, the multienzyme complex pyruvate dehydrogenase at the junction of glycolysis and the citric acid cycle requires ... Other coenzymes, flavin adenine dinucleotide (FAD), biotin, and lipoamide, for instance, are tightly bound. Tightly bound ... ISBN 978-0-8247-4062-7. "Pyruvate Dehydrogenase Complex". Chemistry LibreTexts. 2013-10-02. Retrieved 2017-05-10. Denessiouk KA ... while it is less tightly bound in pyruvate dehydrogenase. ... An example of this are the dehydrogenases that use nicotinamide ...

In humans, arsenite inhibits pyruvate dehydrogenase (PDH complex) in the pyruvate-acetyl CoA reaction, by binding to the -SH ... group of lipoamide, a participant coenzyme. It also inhibits the oxoglutarate dehydrogenase complex by the same mechanism. The ...

Korotchkina LG, Patel MS (Feb 2008). "Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex ... and dihydrolipoyl dehydrogenase (EC 1.8.1.4) regenerates the lipoamide. Because dihydrolipoyl transacetylase is the second of ... There are three different enzyme components in the pyruvate dehydrogenase complex. Pyruvate dehydrogenase (EC 1.2.4.1) is ... is an enzyme component of the multienzyme pyruvate dehydrogenase complex. The pyruvate dehydrogenase complex is responsible for ...

E1 is pyruvate dehydrogenase, which uses thiamine pyrophosphate (TPP) as a cofactor to decarboxylate pyruvate and transfer the ... This results in the formation of acetyl lipoamide, equivalent to reduction of lipoamide (and oxidation of the hydroxyethyl ... Pyruvate catalytic reaction catalyzed by pyruvate dehydrogenase system is a special decarboxylation method, namely oxidative ... Oxidative metabolism entails the further catabolism of pyruvate. The pyruvate dehydrogenase, or PDH complex carries out the ...

People with pyruvate dehydrogenase deficiency usually have neurological problems as well. Most have delayed development of ... "Entrez Gene: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)". Frank RA, Price AJ, Northrop FD, Perham RN, Luisi ... Because of the severe health effects, many individuals with pyruvate dehydrogenase deficiency do not survive past childhood, ... Alpha-ketoglutarate dehydrogenase also known as 2-oxoglutarate dehydrogenase E1 component, mitochondrial is an enzyme that in ...

3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase, [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphate ... Reed LJ, Damuni Z, Merryfield ML (1985). "Regulation of mammalian pyruvate and branched-chain α-keto acid dehydrogenase ... branched-chain oxo-acid dehydrogenase phosphatase, branched-chain 2-keto acid dehydrogenase phosphatase, branched-chain α-keto ... This enzyme catalyses the following chemical reaction [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)] ...

"How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase ... Olsson JM, Xia L, Eriksson LC, Björnstedt M (April 1999). "Ubiquinone is reduced by lipoamide dehydrogenase and this reaction ... "How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase ... Xia L, Björnstedt M, Nordman T, Eriksson LC, Olsson JM (March 2001). "Reduction of ubiquinone by lipoamide dehydrogenase. An ...

Muiswinkel-Voetberg, H.; Visser, Jaap; Veeger, Cornelis (1973). "Conformational Studies on Lipoamide Dehydrogenase from Pig ... Ibsen, KH; Schiller, KW; Haas, TA (1971). "Interconvertible kinetic and physical forms of human erythrocyte pyruvate kinase". ... Muiswinkel-Voetberg, H.; Veeger, Cornelis (1973). "Conformational Studies on Lipoamide Dehydrogenase from Pig Heart. 2. ... "PH-dependent Substrate Preference of Pig Heart Lipoamide Dehydrogenase Varies with Oligomeric State: RESPONSE TO MITOCHONDRIAL ...