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*  Aminooxyacetic acid
... is a general inhibitor of pyridoxal phosphate (PLP)-dependent enzymes (this includes GABA-T). It functions ...
*  Tryptophan synthase
The β subunits catalyze the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) ... The α subunits catalyze the reversible formation of indole and glyceraldehyde-3-phosphate (G3P) from indole-3-glycerol ...
*  Aspartate 4-decarboxylase
It employs one cofactor, pyridoxal phosphate. Kakimoto T, Kato J, Shibatani T, Nishimura N, Chibata I (1969). "Crystalline L- ...
*  Alanine-glyoxylate transaminase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 7 structures have been solved for this class of enzymes, with ...
*  Tyrosine decarboxylase
It employs one cofactor, pyridoxal phosphate. McGilvery RW; Cohen PP (1948). "The decarboxylation of L-phenylalanine by ...
*  2,2-dialkylglycine decarboxylase (pyruvate)
... pyridoxal phosphate. As of late 2007, 16 structures have been solved for this class of enzymes, with PDB accession codes 1D7R, ...
*  Alanine-oxo-acid transaminase
It employs one cofactor, pyridoxal phosphate. ALTENBERN RA, HOUSEWRIGHT RD (1953). "Transaminases in smooth Brucella abortus, ...
*  DTDP-4-amino-4,6-dideoxygalactose transaminase
It employs one cofactor, pyridoxal phosphate. Oashi H, Matsuhashi M, Matsuhashi S (1971). "Thymidine diphosphate 4-acetamido-4, ...
*  8-amino-7-oxononanoate synthase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 4 structures have been solved for this class of enzymes, with ... a pyridoxal-5'-phosphate-dependent enzyme involved in biotin biosynthesis, by substrate and intermediate analogs. Kinetic and ...
*  Glycine dehydrogenase (decarboxylating)
The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor. Carbon dioxide is released and ... It employs one cofactor, pyridoxal phosphate. Glycine decarboxylase is the P-protein of the glycine cleavage system in ... a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a ...
*  Diaminopropionate ammonia-lyase
It employs one cofactor, pyridoxal phosphate. Nagasawa T, Tanizawa K, Satoda T, Yamada H (1988). "Diaminopropionate ammonia- ... and sequence determination of the pyridoxal 5'-phosphate binding peptide". J. Biol. Chem. 263 (2): 958-64. PMID 3275662. ...
*  Serine-glyoxylate transaminase
It employs one cofactor, pyridoxal phosphate. Ireland RJ, Joy KW (1983). "Purification and properties of an asparagine ...
*  Indole test
Pyridoxal phosphate is required as a coenzyme. Like many biochemical tests on bacteria, results of an indole test are indicated ...
*  List of dopaminergic drugs
... pyridoxalpyridoxal phosphate) • Vitamin B9 (folic acid → tetrahydrofolic acid) • Vitamin C (ascorbic acid) • Zinc (Zn2+) ...
*  Serine
SHMT is a pyridoxal phosphate (PLP) dependent enzyme. Glycine can also be formed from CO2, NH4+, and mTHF in a reaction ...
*  Threonine ammonia-lyase
It employs a pyridoxal-5'-phosphate cofactor, similar to many enzymes involved in amino acid metabolism. It is found in ... While the threonine binding site is not perfectly understood, structural studies do reveal how the pyridoxal phosphate cofactor ... April 1998). "Structure and control of pyridoxal phosphate dependent allosteric threonine deaminase". Structure. 6 (4): 465-75 ... Eliot, Andrew C.; Kirsch, Jack F. (2004). "PYRIDOXAL PHOSPHATE ENZYMES: Mechanistic, Structural, and Evolutionary ...
*  Tryptophanase
It has 2 cofactors: pyridoxal phosphate, and Potassium. As of late 2007, 3 structures have been solved for this class of ...
*  Phosphatidylserine decarboxylase
It has 2 cofactors: pyridoxal phosphate, and Pyruvate. KANFER J, KENNEDY EP (1964). "METABOLISM AND FUNCTION OF BACTERIAL ...
*  Cofactor (biochemistry)
Eliot AC, Kirsch JF (2004). "Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations". Annu. Rev ... Noll KM, Rinehart KL, Tanner RS, Wolfe RS (1986). "Structure of component B (7-mercaptoheptanoylthreonine phosphate) of the ... Lipmann F (1941). "Metabolic generation and utilization of phosphate bond energy". Adv Enzymol. 1: 99-162. doi:10.4159/harvard. ... Friedkin M, Lehninger AL (1949). "Esterification of inorganic phosphate coupled to electron transport between ...
*  Hyperprolinemia
Pyridoxal phosphate de-activation by pyrroline-5-carboxylic acid. Increased risk of vitamin B6 deficiency and seizures in ...
*  YjeF N terminal protein domain
Examples of such include: pyridoxal phosphate biosynthetic protein PdxJ; phosphopanteine-protein transferase; ATP/GTP hydrolase ... In plants, the YjeF N-terminal domain is fused to a C-terminal putative pyridoxamine 5'-phosphate oxidase. In eukaryotes, ...
*  2,4-diaminopentanoate dehydrogenase
... pyridoxal phosphate, and pyridine nucleotide". J. Biol. Chem. 245 (22): 5914-26. PMID 4394942. Molecular and Cellular Biology ...
*  Cystathionine gamma-lyase
Pyridoxal phosphate is bound in the active site by Lys212. Cysteine is the rate-limiting substrate in the synthetic pathway for ... Pyridoxal phosphate is necessary to stabilize this carbanionic intermediate; otherwise the proton's pKa would be too high. The ... Pyridoxal phosphate is a prosthetic group of this enzyme. Cystathionine gamma-lyase also catalyses the following elimination ... Cystathionase uses pyridoxal phosphate to facilitate the cleavage of the sulfur-gamma carbon bond of cystathionine, resulting ...
*  D-ornithine 4,5-aminomutase
Somack R, Costilow RN (1973). "Purification and properties of a pyridoxal phosphate and coenzyme B 12 dependent D- -ornithine 5 ... It has 3 cofactors: pyridoxal phosphate, Cobamide coenzyme, and Dithiothreitol. ...
*  Cooperative binding
"Structure and control of pyridoxal phosphate dependent allosteric threonine deaminase". Structure. 6 (4): 465-475. doi:10.1016/ ...
*  Aspartate transaminase
ISBN 978-0-7167-8724-2. Hayashi H, Wada H, Yoshimura T, Esaki N, Soda K (1990). "Recent topics in pyridoxal 5'-phosphate enzyme ... is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and ... In the process, the cofactor shuttles between PLP and the pyridoxamine phosphate (PMP) form. The amino group transfer catalyzed ...
*  Histidinol-phosphate transaminase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 11 structures have been solved for this class of enzymes, with ... histidinol phosphate aminotransferase, imidazoleacetol phosphate transaminase, L-histidinol phosphate aminotransferase, ... 2-oxopropyl phosphate + L-glutamate Thus, the two substrates of this enzyme are L-histidinol phosphate and 2-oxoglutarate, ... In enzymology, a histidinol-phosphate transaminase (EC 2.6.1.9) is an enzyme that catalyzes the chemical reaction L-histidinol ...