Loading...
*  Glycogen phosphorylase
... has a pyridoxal phosphate (PLP, derived from Vitamin B6) at each catalytic site. Pyridoxal phosphate ... Palm D, Klein HW, Schinzel R, Buehner M, Helmreich, EJ (February 1990). "The role of pyridoxal 5'-phosphate in glycogen ... Glycogenolysis PDB: 3E3N​ Livanova NB, Chebotareva NA, Eronina TB, Kurganov BI (May 2002). "Pyridoxal 5′_Phosphate as a ...
*  Aspartate transaminase
ISBN 978-0-7167-8724-2. Hayashi H, Wada H, Yoshimura T, Esaki N, Soda K (1990). "Recent topics in pyridoxal 5'-phosphate enzyme ... is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and ...
*  Pyridoxal
... that are capable of producing pyridoxal. Pyridoxal is involved in what is believed to be the most ancient reaction of aerobic ... Pyridoxal is one form of vitamin B6. Some medically relevant bacteria, such as those in the genera Granulicatella and ... In in vitro culture, these pyridoxal-dependent bacteria may only grow in areas surrounding colonies of bacteria from other ... Abiotrophia, require pyridoxal for growth. This nutritional requirement can lead to the culture phenomenon of satellite growth ...
*  Pyridoxal phosphatase
In enzymology, a pyridoxal phosphatase (EC 3.1.3.74) is an enzyme that catalyzes the chemical reaction pyridoxal 5'-phosphate ... H2O ⇌ {\displaystyle \rightleftharpoons } pyridoxal + phosphate Thus, the two substrates of this enzyme are pyridoxal 5'- ... OS; Kim, DW; Kang, TC; Won, MH; Baek, NI; Moon, BJ; Choi, SY; Kwon, OS (2003). "Human pyridoxal phosphatase. Molecular cloning ... The systematic name of this enzyme class is pyridoxal-5'-phosphate phosphohydrolase. Other names in common use include vitamine ...
*  Pyridoxal oxidase
In enzymology, a pyridoxal oxidase (EC 1.2.3.8) is an enzyme that catalyzes the chemical reaction pyridoxal + H2O + O2 ⇌ {\ ... The systematic name of this enzyme class is pyridoxal:oxygen 4-oxidoreductase. This enzyme participates in vitamin B6 ... I. Preliminary studies of pyridoxal oxidase". Mol. Gen. Genet. 180 (2): 449-453. doi:10.1007/BF00425861. Molecular and Cellular ... Hanly EW (1980). "Preliminary characterization and physical properties of pyridoxal oxidase activity from Drosophila ...
*  Pyridoxal phosphate
... (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic ... PLP is synthesized from pyridoxal by the enzyme pyridoxal kinase, requiring one ATP molecule. PLP is metabolized in the liver. ... The pyridoxal-5′-phosphate-dependent enzymes (PLP enzymes) catalyze myriad biochemical reactions. Although the scope of PLP- ... Vitamin B6: Pyridoxal Phosphate Volume 1, Part B, Coenzymes and Cofactors. Wiley Interscience, New YorkYear: 1986 ISBN 978- ...
*  Pyridoxal kinase
Other names in common use include pyridoxal kinase (phosphorylating), pyridoxal 5-phosphate-kinase, pyridoxal phosphokinase, ... In enzymology, a pyridoxal kinase (EC 2.7.1.35) is an enzyme that catalyzes the chemical reaction ATP + pyridoxal ⇌ {\ ... displaystyle \rightleftharpoons } ADP + pyridoxal 5'-phosphate Thus, the two substrates of this enzyme are ATP and pyridoxal, ... "Biosynthesis of pyridoxal phosphate by liver sections of rat in vitro". Byull. Eksp. Biol. Med. 22: 40-43. Molecular and ...
*  Pyridoxal 4-dehydrogenase
In enzymology, a pyridoxal 4-dehydrogenase (EC 1.1.1.107) is an enzyme that catalyzes the chemical reaction pyridoxal + NAD+ ... The systematic name of this enzyme class is pyridoxal:NAD+ 4-oxidoreductase. This enzyme is also called pyridoxal dehydrogenase ... Pyridoxal dehydrogenase and 4-pyridoxolactonase". J. Biol. Chem. 244 (10): 2585-9. PMID 4306030. Molecular and Cellular Biology ... displaystyle \rightleftharpoons } 4-pyridoxolactone + NADH + H+ Thus, the two substrates of this enzyme are pyridoxal and NAD+ ...
*  Group III pyridoxal-dependent decarboxylases
Group I pyridoxal-dependent decarboxylases Group II pyridoxal-dependent decarboxylases Group IV pyridoxal-dependent ... Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into four groups based on amino acid sequence. Group ... The major domain contains a conserved lysine residue, which is the site of attachment of the pyridoxal-phosphate group. ... In molecular biology, group III pyridoxal-dependent decarboxylases are a family of bacterial enzymes comprising ornithine ...
*  Group II pyridoxal-dependent decarboxylases
Group I pyridoxal-dependent decarboxylases Group III pyridoxal-dependent decarboxylases Group IV pyridoxal-dependent ... Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into four groups based on amino acid sequence. Group ... In molecular biology, group II pyridoxal-dependent decarboxylases are family of enzymes including aromatic-L-amino-acid ... Sandmeier E, Hale TI, Christen P (May 1994). "Multiple evolutionary origin of pyridoxal-5'-phosphate-dependent amino acid ...
*  Group IV pyridoxal-dependent decarboxylases
Group I pyridoxal-dependent decarboxylases Group II pyridoxal-dependent decarboxylases Group III pyridoxal-dependent ... Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into four groups based on amino acid sequence. Group ... The proteins contain a conserved lysine residue which is known, in mouse ODC to be the site of attachment of the pyridoxal- ... In molecular biology, group IV pyridoxal-dependent decarboxylases are a family of enzymes comprising ornithine decarboxylase EC ...
*  Group I pyridoxal-dependent decarboxylases
Group II pyridoxal-dependent decarboxylases Group III pyridoxal-dependent decarboxylases Group IV pyridoxal-dependent ... GDC consists of four proteins P, H, L and T. Pyridoxal-5'-phosphate-dependent amino acid decarboxylases can be divided into ... The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor, carbon dioxide is released and ... In molecular biology, the group I pyridoxal-dependent decarboxylases, also known as glycine cleavage system P-proteins, are a ...
*  Magnesium pyridoxal 5-phosphate glutamate
... (trade name Sedalipid) is a hypolipidemic agent. Schuitemaker GE, van der Pol GA, ... Aretz CP, Dinant GJ (2001). "A placebo-controlled, double-blind, randomised trial of magnesium-pyridoxal-5'-phosphate-glutamate ...
*  Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)
... (EC 4.3.3.6, PdxST) is an enzyme with systematic name D-ribose 5- ... Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) at the US National Library of Medicine Medical Subject Headings (MeSH) ... Hanes, J.W.; Keresztes, I.; Begley, T.P. (2008). "13C NMR snapshots of the complex reaction coordinate of pyridoxal phosphate ... Raschle, T.; Amrhein, N.; Fitzpatrick, T.B. (2005). "On the two components of pyridoxal 5′-phosphate synthase from Bacillus ...
*  Branched-chain amino acid aminotransferase
Toney MD (November 2011). "Pyridoxal phosphate enzymology". Biochimica et Biophysica Acta. Pyridoxal Phosphate Enzymology. 1814 ... Like other transaminase enzymes (as well as many enzymes of other classes), BCATs require the cofactor pyridoxal-5'-phosphate( ...
*  PDXK
Pyridoxal kinase is an enzyme that in humans is encoded by the PDXK gene. The protein encoded by this gene phosphorylates ... "Entrez Gene: PDXK pyridoxal (pyridoxine, vitamin B6) kinase". Chern CJ, Beutler E (1976). "Biochemical and electrophoretic ... 2004). "Expression of a novel pyridoxal kinase mRNA splice variant, PKH-T, in human testis". Asian J. Androl. 6 (2): 83-91. ... Lainé-Cessac P, Cailleux A, Allain P (1997). "Mechanisms of the inhibition of human erythrocyte pyridoxal kinase by drugs". ...
*  Cys/Met metabolism PLP-dependent enzyme family
A number of pyridoxal-dependent enzymes involved in the metabolism of cysteine, homocysteine and methionine have been shown to ... PLP is the active form of vitamin B6 (pyridoxine or pyridoxal). PLP is a versatile catalyst, acting as a coenzyme in a ... Toney MD (January 2005). "Reaction specificity in pyridoxal phosphate enzymes". Arch. Biochem. Biophys. 433 (1): 279-87. doi: ... John RA (April 1995). "Pyridoxal phosphate-dependent enzymes". Biochim. Biophys. Acta. 1248 (2): 81-96. doi:10.1016/0167-4838( ...
*  Histidine decarboxylase
"Pyridoxal phosphate-dependent decarboxylase". InterPro. Toney, Michael D. (2005-01-01). "Reaction specificity in pyridoxal ... HDC contains several regions that are sequentially and structurally similar to those in a number of other pyridoxal-dependent ... The enzyme employs a pyridoxal 5'-phosphate (PLP) cofactor, in similarity to many amino acid decarboxylases. Eukaryotes, as ... Histidine decarboxylase is a group II pyridoxal-dependent decarboxylase, along with aromatic-L-amino-acid decarboxylase, and ...
*  Cystathionine beta-lyase
The enzyme belongs to the γ-family of PLP-dependent enzymes due to its use of a pyridoxal-5'-phosphate (PLP) cofactor to cleave ... Clausen, T.; Huber, R.; Laber, B.; Pohlenz, H. D.; Messerschmidt, A. (1996-09-20). "Crystal structure of the pyridoxal-5'- ... John, R. A. (1995-04-27). "Pyridoxal phosphate-dependent enzymes". Biochimica et Biophysica Acta. 1248 (2): 81-96. doi:10.1016/ ... Alexander, F. W.; Sandmeier, E.; Mehta, P. K.; Christen, P. (1994-02-01). "Evolutionary relationships among pyridoxal-5'- ...
*  4-pyridoxolactonase
Pyridoxal dehydrogenase and 4-pyridoxolactonase". J. Biol. Chem. 244 (10): 2585-9. PMID 4306030. Molecular and Cellular Biology ...
*  Acetylornithine transaminase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 6 structures have been solved for this class of enzymes, with ...
*  Beta-alanine-pyruvate transaminase
It employs one cofactor, pyridoxal phosphate. HAYAISHI O, NISHIZUKA Y, TATIBANA M, TAKESHITA M, KUNO S (1961). "Enzymatic ...
*  Asparagine-oxo-acid transaminase
It employs one cofactor, pyridoxal phosphate. MEISTER A, FRASER PE (1954). "Enzymatic formation of L-asparagine by ...
*  Adenosylmethionine-8-amino-7-oxononanoate transaminase
It employs one cofactor, pyridoxal phosphate. As of late 2007, 11 structures have been solved for this class of enzymes, with ...
*  L-seryl-tRNASec selenium transferase
It employs one cofactor, pyridoxal phosphate. Forchhammer K, Bock A (1991). "Selenocysteine synthase from Escherichia coli. ...